Recurrent myoepithelial carcinoma of the submandibular gland treated by rAd‑p53 combined with radiotherapy: A case report
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- Published online on: June 16, 2016 https://doi.org/10.3892/ol.2016.4746
- Pages: 915-917
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Abstract
The aim of the present study was to report the case of a patient with recurrent myoepithelial carcinoma of the submandibular gland without progression for five years following treatment. A 71‑year‑old male patient presented to hospital with a painless swelling in the region of the right submandibular gland, and received a radical neck dissection on January 29, 2008. A nodule of ~7x4x2 cm was identified at the site of the right submandibular gland, and the pathological results revealed a diagnosis of myoepithelial carcinoma of the right submandibular gland with no lymph node metastasis. However, this case developed local recurrence with wide‑spread metastasis in the lungs. Between April and October 2008, the patient underwent several treatment regimens and demonstrated no improvement following 6 cycles of chemotherapy. From then on, the patient was treated with recombinant adenoviral‑p53 (rAd‑p53) combined with radiotherapy using a 6 millivolt medical linear accelerator. The foci were relieved and the cancer demonstrated no signs of progression during the 5‑year follow‑up. rAd‑p53 combined with radiotherapy was useful for treating myoepithelial carcinoma of the submandibular gland.
