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Case Report

Carcinoma-like nonfunctional pheochromocytoma in the right adrenal gland: A case report

Corrigendum in: /10.3892/ol.2016.5144
  • Authors:
    • Shingo Moriyama
    • Hideki Takeshita
    • Saori Araki
    • Takuo Tokairin
    • Makoto Kagawa
    • Koji Chiba
    • Akiko Adachi
    • Akira Noro
  • View Affiliations / Copyright

    Affiliations: Department of Urology, Saitama Red Cross Hospital, Saitama 338‑8553, Japan, Department of Pathology, Saitama Red Cross Hospital, Saitama 338‑8553, Japan
  • Pages: 1489-1492
    |
    Published online on: June 23, 2016
       https://doi.org/10.3892/ol.2016.4776
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Abstract

Evaluation of the malignant potential of a pheochromocytoma (PCC) remains controversial. PCC is regarded as a neuroendocrine tumor (NET), and the classification of NETs has gradually been defined over the last decade, particularly for gastroenteropancreatic NET. The present study describes a case of locally advanced, carcinoma‑like, nonfunctional PCC, which may be regarded as neuroendocrine carcinoma (NEC) rather than a malignant PCC. A 72‑year‑old man was referred to Saitama Red Cross Hospital (Saitama, Japan), presenting with a 2‑month history of right flank pain. Computed tomography revealed a right adrenal gland tumor, which measured 6.0 cm in diameter, invading the hilum of the right kidney, liver and inferior vena cava (IVC). Radical surgery was performed with en bloc resection of the right kidney, and adjacent parts of the liver and IVC. Immunohistochemical examination demonstrated that all of the resected tissues were positive for cytokeratin AE1/AE3, chromogranin A, synaptophysin, cluster of differentiation 56 and Ki-67, and the specimen had a Ki‑67 index of 80%. A diagnosis of carcinoma‑like PCC or NEC of the adrenal gland was confirmed. Reports of NEC of the adrenal gland are extremely rare in the literature, and classification of PCC as a NET has not yet been fully discussed. The present case may therefore contribute to the classification of NETs in the adrenal gland.
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Copy and paste a formatted citation
Spandidos Publications style
Moriyama S, Takeshita H, Araki S, Tokairin T, Kagawa M, Chiba K, Adachi A and Noro A: Carcinoma-like nonfunctional pheochromocytoma in the right adrenal gland: A case report Corrigendum in /10.3892/ol.2016.5144. Oncol Lett 12: 1489-1492, 2016.
APA
Moriyama, S., Takeshita, H., Araki, S., Tokairin, T., Kagawa, M., Chiba, K. ... Noro, A. (2016). Carcinoma-like nonfunctional pheochromocytoma in the right adrenal gland: A case report Corrigendum in /10.3892/ol.2016.5144. Oncology Letters, 12, 1489-1492. https://doi.org/10.3892/ol.2016.4776
MLA
Moriyama, S., Takeshita, H., Araki, S., Tokairin, T., Kagawa, M., Chiba, K., Adachi, A., Noro, A."Carcinoma-like nonfunctional pheochromocytoma in the right adrenal gland: A case report Corrigendum in /10.3892/ol.2016.5144". Oncology Letters 12.2 (2016): 1489-1492.
Chicago
Moriyama, S., Takeshita, H., Araki, S., Tokairin, T., Kagawa, M., Chiba, K., Adachi, A., Noro, A."Carcinoma-like nonfunctional pheochromocytoma in the right adrenal gland: A case report Corrigendum in /10.3892/ol.2016.5144". Oncology Letters 12, no. 2 (2016): 1489-1492. https://doi.org/10.3892/ol.2016.4776
Copy and paste a formatted citation
x
Spandidos Publications style
Moriyama S, Takeshita H, Araki S, Tokairin T, Kagawa M, Chiba K, Adachi A and Noro A: Carcinoma-like nonfunctional pheochromocytoma in the right adrenal gland: A case report Corrigendum in /10.3892/ol.2016.5144. Oncol Lett 12: 1489-1492, 2016.
APA
Moriyama, S., Takeshita, H., Araki, S., Tokairin, T., Kagawa, M., Chiba, K. ... Noro, A. (2016). Carcinoma-like nonfunctional pheochromocytoma in the right adrenal gland: A case report Corrigendum in /10.3892/ol.2016.5144. Oncology Letters, 12, 1489-1492. https://doi.org/10.3892/ol.2016.4776
MLA
Moriyama, S., Takeshita, H., Araki, S., Tokairin, T., Kagawa, M., Chiba, K., Adachi, A., Noro, A."Carcinoma-like nonfunctional pheochromocytoma in the right adrenal gland: A case report Corrigendum in /10.3892/ol.2016.5144". Oncology Letters 12.2 (2016): 1489-1492.
Chicago
Moriyama, S., Takeshita, H., Araki, S., Tokairin, T., Kagawa, M., Chiba, K., Adachi, A., Noro, A."Carcinoma-like nonfunctional pheochromocytoma in the right adrenal gland: A case report Corrigendum in /10.3892/ol.2016.5144". Oncology Letters 12, no. 2 (2016): 1489-1492. https://doi.org/10.3892/ol.2016.4776
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