Perineal leiomyoma in a postmenopausal woman: A case report

Sui,Yan‑Xia; Sun,Chao; Lv,Shu‑Lan; Batchu,Nasra; Zou,Jun‑Kai; Du,Jiang; Song,Qing; Li,Qi‑Ling

doi:10.3892/ol.2016.4830

September-2016 Volume 12 Issue 3

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September-2016 Volume 12 Issue 3

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Case Report

Perineal leiomyoma in a postmenopausal woman: A case report

Authors:
- Yan‑Xia Sui
- Chao Sun
- Shu‑Lan Lv
- Nasra Batchu
- Jun‑Kai Zou
- Jiang Du
- Qing Song
- Qi‑Ling Li
View Affiliations / Copyright

Affiliations: Department of Obstetrics and Gynecology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China
Pages: 2045-2047
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Published online on: July 8, 2016

https://doi.org/10.3892/ol.2016.4830
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Abstract

Leiomyomas in the female reproductive system are commonly located in the uterus and typically regress following the menopause. Vulval leiomyomas are rare, and to the best of our knowledge, perineal leiomyomas in postmenopausal women have not been previously reported in the literature. The present case describes a 60‑year‑old Chinese woman who experienced perineal tenderness and lumbosacral radiating pain. The patient, who went through the menopause 12 years previously, had presented with a painful perineal mass for 1 year, which was subsequently diagnosed as a postmenopausal perineal leiomyoma. The mass was locally resected, and histopathological examination of the lesion resulted in a diagnosis of benign epithelioid leiomyoma. Immunohistochemical staining identified that the leiomyoma was positive for estrogen receptor and negative for progesterone receptor expression. The patient was followed up for 1 year and did not experience any pain or recurrence. The symptoms of local and lumbosacral radiating pain are extremely rare and may be induced by peripheral nerve stimulation. The etiology of postmenopausal perineal leiomyoma may be associated with infection, dietary, stress and environmental factors, and the role of estrogen cannot be overemphasized in cases of postmenopausal leiomyoma.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Perineal leiomyoma in a postmenopausal woman: A case report

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