Globose, cystic olfactory ensheathing cell tumor: A case report and literature review

Liu,Yaoling; Wei,Minghai; Yang,Kang; Tan,Zeshi; Sun,Xu; Li,Xinyu; Che,Ningwei; Luan,Lan; Wang,Guanyu; Wang,Xiaofeng; Sun,Yuqiang; Yin,Jian

doi:10.3892/ol.2016.5131

November-2016 Volume 12 Issue 5

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

November-2016 Volume 12 Issue 5

Full Size Image

Case Report

Globose, cystic olfactory ensheathing cell tumor: A case report and literature review

Authors:
- Yaoling Liu
- Minghai Wei
- Kang Yang
- Zeshi Tan
- Xu Sun
- Xinyu Li
- Ningwei Che
- Lan Luan
- Guanyu Wang
- Xiaofeng Wang
- Yuqiang Sun
- Jian Yin
View Affiliations / Copyright

Affiliations: Department of Neurosurgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, P.R. China
Pages: 3981-3986
|
Published online on: September 14, 2016

https://doi.org/10.3892/ol.2016.5131
Expand metrics +

Abstract

Olfactory ensheathing cell tumor (OECT) is one of the most rare intracranial, extra-axial tumors located in the anterior cranial fossa. The present study reports a case of a 34‑year‑old female patient who presented with a history of hyposmia for 1 year, as well as a gradual dizziness and emotional lability for 2 months. Magnetic resonance imaging of the brain revealed a globose, well‑defined cystic mass at the midline of the anterior cranial fossa, which was confirmed as an OECT by histology and was completely resected by bifrontal craniotomy. According to the immunostaining results, the tumor was positive for vimentin and S100 protein, and negative for epithelial membrane antigen, glial fibrillary acidic protein and cluster of differentiation 57 (also known as Leu‑7). The presentation, imaging findings, histopathological examination and histogenesis of OECT are discussed in the present study, along with a literature review.

View Figures

View References

1	Wewetzer K, Verdú E, Angelov DN and Navarro X: Olfactory ensheathing glia and Schwann cells: Two of a kind? Cell Tissue Res. 309:337–345. 2002. View Article : Google Scholar : PubMed/NCBI
2	Yasuda M, Higuchi O, Takano S and Matsumura A: Olfactory ensheathing cell tumor: A case report. J Neurooncol. 76:111–113. 2006. View Article : Google Scholar : PubMed/NCBI
3	Salunke P, Patra DP, Futane S and Nada R: Olfactory region schwannoma: Excision with preservation of olfaction. J Neurosci Rural Pract. 5:281–283. 2014. View Article : Google Scholar : PubMed/NCBI
4	Figueiredo EG, Soga Y, Amorim RL, Oliveira AM and Teixeira MJ: The puzzling olfactory groove schwannoma: A systematic review. Skull Base. 21:31–36. 2011. View Article : Google Scholar : PubMed/NCBI
5	Ippili K, Ratnam BG, Gowrishankar S, Ranjan A and Lath R: Olfactory ensheathing cell tumor. Neurol India. 57:76–78. 2009. View Article : Google Scholar : PubMed/NCBI
6	Darie I, Riffaud L, Saïkali S, Brassier G and Hamlat A: Olfactory ensheathing cell tumour: Case report and literature review. J Neurooncol. 100:285–289. 2010. View Article : Google Scholar : PubMed/NCBI
7	Lin SC, Chen MH, Lin CF and Ho DM: Olfactory ensheathing cell tumor with neurofibroma-like features: A case report and review of the literature. J Neurooncol. 97:117–122. 2010. View Article : Google Scholar : PubMed/NCBI
8	Yamaguchi T, Fujii H, Dziurzynski K, Delashaw JB and Watanabe E: Olfactory ensheathing cell tumor: Case report. Skull Base. 20:357–361. 2010. View Article : Google Scholar : PubMed/NCBI
9	Ogino-Nishimura E, Nakagawa T, Mikami Y and Ito J: Olfactory ensheathing cell tumor arising from the olfactory mucosa. Case Rep Med. 2012:4268532012.PubMed/NCBI
10	Al-Ghanem R, Ramos-Pleguezuelos FM, Pérez-Darosa SI, Galicia-Bulnes JM, Cabrerizo-Carvajal F and El-Rubaidi OA: Olfactory ensheathing cell tumour: Case report and literature review. Neurocirugia (Astur). 24:130–134. 2013.(In Spanish). View Article : Google Scholar : PubMed/NCBI
11	Qi X, Wan Y, Yan Q, Wang Y and Yang S: Cystic olfactory ensheathing cell tumor: A case report. Acta Neurol Belg. 115:191–193. 2015. View Article : Google Scholar : PubMed/NCBI
12	Li YP, Jiang S, Zhou PZ and Ni YB: Solitary olfactory schwannoma without olfactory dysfunction: A new case report and literature review. Neurol Sci. 33:137–142. 2012. View Article : Google Scholar : PubMed/NCBI
13	Vincent AJ, Taylor JM, Choi-Lundberg DL, West AK and Chuah MI: Genetic expression profile of olfactory ensheathing cells is distinct from that of Schwann cells and astrocytes. Glia. 51:132–147. 2005. View Article : Google Scholar : PubMed/NCBI
14	Bianco JI, Perry C, Harkin DG, Mackay-Sim A and Féron F: Neurotrophin 3 promotes purification and proliferation of olfactory ensheathing cells from human nose. Glia. 45:111–123. 2004. View Article : Google Scholar : PubMed/NCBI
15	Wang Z, Zhang W, You G, Wang J, Li G, Gao Z and Xie J: Olfactory schwannoma: A report of two cases and literature review. Neurol India. 62:429–431. 2014. View Article : Google Scholar : PubMed/NCBI
16	Johnson MD, Glick AD and Davis BW: Immunohistochemical evaluation of Leu-7, myelin basic-protein, S100-protein, glial-fibrillary acidic-protein, and LN3 immunoreactivity in nerve sheath tumors and sarcomas. Arch Pathol Lab Med. 112:155–160. 1988.PubMed/NCBI
17	Santhosh K, Kesavadas C, Radhakrishnan VV, Thomas B, Kapilamoorthy TR and Gupta AK: Usefulness of T2*-weighted MR sequence for the diagnosis of subfrontal schwannoma. J Neuroradiol. 34:330–333. 2007. View Article : Google Scholar : PubMed/NCBI
18	Yamahata H, Hirahara K, Tomosugi T, Yamada M, Ishii T, Ishigami T, Uetsuhara K, Sueyoshi K, Matsukida S, Yatsushiro K and Arita K: Subfrontal schwannoma mimicking neuroblastoma: Case report. Skull Base Rep. 1:59–64. 2011. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Globose, cystic olfactory ensheathing cell tumor: A case report and literature review

This article is mentioned in:

Abstract

Figure 1

Figure 2

Related Articles