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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2016 Volume 12 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

RNA interference in head and neck oncology (Review)

Agnieszka Sobecka, Wojciech Barczak, Wiktoria Maria Suchorska
Pages: 3035-3040
Published online on: 02 September 2016

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Article Open Access

Genetics and epigenetics of melanoma (Review) Retraction in /10.3892/ol.2020.12045

Xiao-Ying Zhang, Pei-Ying Zhang
Pages: 3041-3044
Published online on: 05 September 2016

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Review Open Access

The Ras/Raf/MEK/ERK signaling pathway and its role in the occurrence and development of HCC (Review)

Lei Li, Guo‑Dong Zhao, Zhe Shi, Li‑Li Qi, Li‑Yuan Zhou, Ze‑Xian Fu
Pages: 3045-3050
Published online on: 09 September 2016

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Review Open Access

New emerging therapies in the management of chronic lymphocytic leukemia (Review)

Xiao‑Lin Li, Ci‑Xian Zhang
Pages: 3051-3054
Published online on: 09 September 2016

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Article Open Access

Recent perspectives of epithelial ovarian carcinoma (Review) Retraction in /10.3892/ol.2020.12046

Xiao-Ying Zhang, Pei-Ying Zhang
Pages: 3055-3058
Published online on: 09 September 2016

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Review Open Access

Radiation induces the generation of cancer stem cells: A novel mechanism for cancer radioresistance (Review)

Fengsheng Li, Kunming Zhou, Ling Gao, Bin Zhang, Wei Li, Weijuan Yan, Xiujun Song, Huijie Yu, Sinian Wang, Nan Yu, Qisheng Jiang
Pages: 3059-3065
Published online on: 12 September 2016

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Article Open Access

Increased expression of long non-coding RNA XIST predicts favorable prognosis of cervical squamous cell carcinoma subsequent to definitive chemoradiation therapy

Reiko Kobayashi, Ryu Miyagawa, Hideomi Yamashita, Teppei Morikawa, Kae Okuma, Masashi Fukayama, Kuni Ohtomo, Keiichi Nakagawa
Pages: 3066-3074
Published online on: 26 August 2016

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Article

Analysis of the molecular mechanism of osteosarcoma using a bioinformatics approach

Jianxun Yang, Ning Wang
Pages: 3075-3080
Published online on: 29 August 2016

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Article Open Access

Heteroplasmy of mutant mitochondrial DNA A10398G and analysis of its prognostic value in non-small cell lung cancer

Yuexiao Qi, Yuehua Wei, Qiaoli Wang, Hui Xu, You Wang, Anqi Yao, Hui Yang, Yan Gao, Fuxiang Zhou
Pages: 3081-3088
Published online on: 05 September 2016

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Article Open Access

Prognostic significance of the expression of nuclear eukaryotic translation initiation factor 5A2 in human melanoma

Shahram Khosravi, Magdalena Martinka, Youwen Zhou, Christopher J. Ong
Pages: 3089-3100
Published online on: 29 August 2016

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Article Open Access

Diagnostic usefulness of the Risk of Ovarian Malignancy Algorithm using the electrochemiluminescence immunoassay for HE4 and the chemiluminescence microparticle immunoassay for CA125

Anita Chudecka‑Głaz, Aneta Cymbaluk‑Płoska, Katarzyna Luterek‑Puszyńska, Janusz Menkiszak
Pages: 3101-3114
Published online on: 29 August 2016

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Article Open Access

FISH testing of HER2 immunohistochemistry 1+ invasive breast cancer with unfavorable characteristics

Stella Petroni, Lucia Caldarola, Rachele Scamarcio, Francesco Giotta, Agnese Latorre, Anita Mangia, Giovanni Simone
Pages: 3115-3122
Published online on: 13 September 2016

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Article Open Access

The targetable role of herpes virus-associated ubiquitin-specific protease (HAUSP) in p190 BCR-ABL leukemia

Giovanna Carrà, Cristina Panuzzo, Sabrina Crivellaro, Deborah Morena, Riccardo Taulli, Angelo Guerrasio, Giuseppe Saglio, Alessandro Morotti
Pages: 3123-3126
Published online on: 01 September 2016

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Article Open Access

Efficacy and safety of aflibercept in metastatic colorectal cancer pretreated with bevacizumab: A report of five cases

Julia Alcaide, Mayte Delgado, Marta Legerén, José Miguel Jurado, Isabel Blancas, Teresa Pereda, Jorge López, Margarita Garrido, María J. Sánchez, José L. García, Antonio Rueda
Pages: 3127-3134
Published online on: 30 August 2016

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Article Open Access

Expression patterns of maspin and mutant p53 are associated with the development of gestational trophoblastic neoplasia

Pengming Sun, Qibin Wu, Guanyu Ruan, Xiu Zheng, Yiyi Song, Jianfan Zhun, Lixiang Wu, Walter H. Gotlieb
Pages: 3135-3142
Published online on: 01 September 2016

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Article Open Access

Validation of the diagnostic utility of urinary midkine for the detection of bladder cancer

Dana Vu Van, Ulrike Heberling, Manfred P. Wirth, Susanne Fuessel
Pages: 3143-3152
Published online on: 23 August 2016

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Article Open Access

In vitro antitumor activity of Latcripin-15 regulator of chromosome condensation 1 domain protein

Li Tian, Xiaoli Wang, Xingyun Li, Ben Liu, Wei Zhang, Jing Cao, Anhong Ning, Min Huang, Mintao Zhong
Pages: 3153-3160
Published online on: 08 September 2016

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Article Open Access

Low extracellular lysyl oxidase expression is associated with poor prognosis in patients with prostate cancer

Wei Zheng, Xuejian Wang, Qiwei Chen, Kun Fang, Lina Wang, Feng Chen, Xiancheng Li, Ziyao Li, Jianbo Wang, Yingxi Liu, Deyong Yang, Xishuang Song
Pages: 3161-3166
Published online on: 12 September 2016

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Article Open Access

NaHCO3 enhances the antitumor activities of cytokine-induced killer cells against hepatocellular carcinoma HepG2 cells

Ya Hong Yuan, Chun Fang Zhou, Jiang Yuan, Li Liu, Xing Rong Guo, Xiao Li Wang, Yan Ding, Xiao Nan Wang, Dong Sheng Li, Han Jun Tu
Pages: 3167-3174
Published online on: 09 September 2016

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Article Open Access

Analysis of clinicopathological characteristics associated with the outcome of oral squamous cell carcinoma and the establishment of tissue microarrays

Xin Jin, Dongjuan Liu, Xin Zhao, Yu Zhou, Lu Jiang, Jing Li, Xin Zeng, Qianming Chen
Pages: 3175-3182
Published online on: 12 September 2016

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Article Open Access

Aspirin inhibits the proliferation and migration of gastric cancer cells in p53-knockout mice

Xue-Fu Li, Bing-Zhong Xu, Shi-Zhen Wang
Pages: 3183-3186
Published online on: 30 August 2016

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Article Open Access

Treatment effects of oxaliplatin combined with gemcitabine on colorectal cancer and its influence on HMGB1 expression

Shuangshuang Wen, Xiaopeng Du, Yanyan Gou, Lin Jiang
Pages: 3187-3190
Published online on: 26 August 2016

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Article Open Access

The effect and clinical efficacy of lienal polypeptide injection combined with FOLFOX chemotherapy regimen in colon cancer patients

Juan Zhou, Guoping Niu, Yunfeng Pei, Chunping Cao, Chen Ding, Guangming Sun, Jing Guo, Yong Liu, Yang Yu
Pages: 3191-3194
Published online on: 29 August 2016

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Article Open Access

Expression and significance of SOX2 in non-small cell lung carcinoma

Jie Ying, Chao Shi, Chuan‑Sheng Li, Li‑Ping Hu, Wei‑Dong Zhang
Pages: 3195-3198
Published online on: 30 August 2016

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Article Open Access

HuR and podoplanin expression is associated with a high risk of malignant transformation in patients with oral preneoplastic lesions

Umma Habiba, Tetsuya Kitamura, Aya Yanagawa‑Matsuda, Fumihiro Higashino, Kyoko Hida, Yasunori Totsuka, Masanobu Shindoh
Pages: 3199-3207
Published online on: 29 August 2016

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Article Open Access

Increased expression of microRNA-148a in osteosarcoma promotes cancer cell growth by targeting PTEN

Hao Zhang, Yang Wang, Tianming Xu, Chen Li, Jiang Wu, Qianyun He, Guangchao Wang, Chen Ding, Kang Liu, Hao Tang, Fang Ji
Pages: 3208-3214
Published online on: 26 August 2016

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Article Open Access

Possible role of thymidine phosphorylase in gynecological tumors as an individualized treatment strategy

Masako Shida, Masanori Yasuda, Mariko Fujita, Masaki Miyazawa, Hiroshi Kajiwara, Takeshi Hirasawa, Masae Ikeda, Naruaki Matsui, Toshinari Muramatsu, Mikio Mikami
Pages: 3215-3223
Published online on: 02 September 2016

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Case Report Open Access

Metastasis of renal cell carcinoma to the parathyroid gland 16 years after radical nephrectomy: A case report

Liborio Torregrossa, Maria Isabella Rotondo, Andrea Cacciato Insilla, David Galleri, Federica Guidoccio, Paolo Miccoli, Virginia A. Livolsi, Fulvio Basolo
Pages: 3224-3228
Published online on: 31 August 2016

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Article Open Access

Methylation of promoter region of CDX2 gene in colorectal cancer

Yunshuai Wang, Zhaohui Li, Wenxian Li, Shuaifeng Liu, Baowei Han
Pages: 3229-3233
Published online on: 09 September 2016

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Article Open Access

mTOR downstream effectors, 4EBP1 and eIF4E, are overexpressed and associated with HPV status in precancerous lesions and carcinomas of the uterine cervix

Aristidis Asimomytis, Maria Karanikou, Alexander Rodolakis, Anna Vaiopoulou, Paraskevi Tsetsa, George Creatsas, Theodoros Stefos, Aristidis Antsaklis, Efstratios Patsouris, George Z. Rassidakis
Pages: 3234-3240
Published online on: 29 August 2016

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Article Open Access

Tumor-penetration and antitumor efficacy of cetuximab are enhanced by co-administered iRGD in a murine model of human NSCLC

Yang Zhang, Jie Yang, Manhua Ding, Liantao Li, Zheng Lu, Qing Zhang, Junnian Zheng
Pages: 3241-3249
Published online on: 02 September 2016

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Article Open Access

Microarray analysis of differentially-expressed genes and linker genes associated with the molecular mechanism of colorectal cancer

Xingjie Shen, Meng Yue, Fansheng Meng, Jingyu Zhu, Xiaoyan Zhu, Yakun Jiang
Pages: 3250-3258
Published online on: 12 September 2016

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Article Open Access

Periareolar incision for the management of benign breast tumors

Xiangnan Kong, Xi Chen, Liyu Jiang, Tingting Ma, Baosan Han, Qifeng Yang
Pages: 3259-3263
Published online on: 12 September 2016

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Article Open Access

Beside P53 and PTEN: Identification of molecular alterations of the RAS/MAPK and PI3K/AKT signaling pathways in high-grade serous ovarian carcinomas to determine potential novel therapeutic targets

Shuhui Chen, Elisa Cavazza, Catherine Barlier, Julia Salleron, Pierre Filhine‑Tresarrieu, Céline Gavoille, Jean‑Louis Merlin, Alexandre Harlé
Pages: 3264-3272
Published online on: 02 September 2016

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Article Open Access

Predictive value of microparticle-associated tissue factor activity for permeability glycoprotein-mediated multidrug resistance in cancer

Antonio Angelini, Sebastiano Miscia, Maria Antonietta Centurione, Roberta Di Pietro, Lucia Centurione
Pages: 3273-3277
Published online on: 08 September 2016

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Article Open Access

Targeting of the leukemia microenvironment by c(RGDfV) overcomes the resistance to chemotherapy in acute myeloid leukemia in biomimetic polystyrene scaffolds

Zhao‑Hua Shen, Dong‑Feng Zeng, Xiao-Yan Wang, Ying‑Ying Ma, Xi Zhang, Pei‑Yan Kong
Pages: 3278-3284
Published online on: 24 August 2016

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Article Open Access

Systematic tracking of disrupted modules identifies significant genes and pathways in hepatocellular carcinoma

Meng‑Hui Zhang, Qin‑Hai Shen, Zhao‑Min Qin, Qiao‑Ling Wang, Xi Chen
Pages: 3285-3295
Published online on: 23 August 2016

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Article Open Access

Quantitative label-free mass spectrometry analysis of formalin-fixed, paraffin-embedded tissue representing the invasive cutaneous malignant melanoma proteome

Paul Dowling, Benvon Moran, Edel McAuley, Paula Meleady, Michael Henry, Martin Clynes, Mairin McMenamin, Niamh Leonard, Mary Monks, Bairbre Wynne, Patrick Ormond, Annemarie Larkin
Pages: 3296-3304
Published online on: 07 September 2016

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Article Open Access

Testin (TES) as a candidate tumour suppressor and prognostic marker in human astrocytoma

Giedrius Steponaitis, Arunas Kazlauskas, Daina Skiriute, Indre Valiulyte, Kestutis Skauminas, Arimantas Tamasauskas, Paulina Vaitkiene
Pages: 3305-3311
Published online on: 01 September 2016

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Article

Expression level of CRKL and AXL combined with exon 19 deletion in EGFR and ALK status confer differential prognosis of lung adenocarcinoma subtypes

Yi‑Ran Cai, Yu‑Jie Dong, Hong‑Bo Wu, Da‑Ping Yu, Li‑Juan Zhou, Dan Su, Li Zhang, Xue‑Jing Chen
Pages: 3312-3322
Published online on: 02 September 2016

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Article Open Access

Colorectal cancer patients exhibit increased levels of galanin in serum and colon tissues

Przemysław Kwiatkowski, Janusz Godlewski, Jacek Kieżun, Bartłomiej Emil Kraziński, Zbigniew Kmieć
Pages: 3323-3329
Published online on: 23 August 2016

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Article Open Access

Involvement of TP53 and TP16 expression in human papillomavirus-associated non-small cell lung cancer

Ming Li, Xiao‑Lei Zhang, Fang Deng, Li‑Ting Qian, Shui‑Ping Meng, Wu‑Lin Shan, Bao‑Long Wang
Pages: 3330-3336
Published online on: 05 September 2016

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Article Open Access

Expression of glucose transporter-1 is correlated with hypoxia-inducible factor 1α and malignant potential in pancreatic neuroendocrine tumors

Minoru Fujino, Shinichi Aishima, Koji Shindo, Yasunori Oda, Katsuya Morimatsu, Kosuke Tsutsumi, Takao Otsuka, Masao Tanaka, Yoshinao Oda
Pages: 3337-3343
Published online on: 05 September 2016

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Article Open Access

Therapeutic targeting of liver cancer with a recombinant DNA vaccine containing the hemagglutinin-neuraminidase gene of Newcastle disease virus via apoptotic-dependent pathways

Li‑Gang Chen, Yuan‑Sheng Liu, Tang‑Hui Zheng, Xu Chen, Ping Li, Chuan‑Xing Xiao, Jian‑Lin Ren
Pages: 3344-3350
Published online on: 09 September 2016

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Article Open Access

APRIL, BCMA and TACI proteins are abnormally expressed in non-small cell lung cancer

Hengli Dou, Zhaohua Yan, Meng Zhang, Xiaoxin Xu
Pages: 3351-3355
Published online on: 06 September 2016

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Article Open Access

Role of specific DNA mutations in the peripheral blood of colorectal cancer patients for the assessment of tumor stage and residual disease following tumor resection

Gregor Norcic, Franc Jelenc, Petra Cerkovnik, Vida Stegel, Srdjan Novakovic
Pages: 3356-3362
Published online on: 01 September 2016

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Article Open Access

Fluoro-edenite induces fibulin-3 overexpression in non-malignant human mesothelial cells

Venerando Rapisarda, Rossella Salemi, Andrea Marconi, Carla Loreto, Adriana C. Graziano, Venera Cardile, Maria S. Basile, Saverio Candido, Luca Falzone, Demetrios A. Spandidos, Concettina Fenga, Massimo Libra
Pages: 3363-3367
Published online on: 26 August 2016

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Article Open Access

The effect of activated Mφ1 on γδT cell-mediated killing of gastric cancer cells in vitro

Wu Xia, Sun Han, Zhang Bao, Jia Fangyuan, Wu Ping
Pages: 3368-3372
Published online on: 30 August 2016

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Article Open Access

Anti-tumoral activity of native compound morelloflavone in glioma

Xianfeng Li, Hongyan Ai, Deke Sun, Tao Wu, Jian He, Zhai Xu, Li Ding, Ling Wang
Pages: 3373-3377
Published online on: 05 September 2016

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Article

Discovery of genes from feces correlated with colorectal cancer progression

Chia‑Long Lee, Chi‑Jung Huang, Shung‑Haur Yang, Chun‑Chao Chang, Chi‑Cheng Huang, Chih‑Cheng Chien, Ruey‑Neng Yang
Pages: 3378-3384
Published online on: 31 August 2016

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Article

Early diagnosis and treatment of gastrointestinal neuroendocrine tumors

Hong Shen, Zhuo Yu, Jing Zhao, Xiu‑Zhen Li, Wen‑Sheng Pan
Pages: 3385-3392
Published online on: 29 August 2016

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Article

A novel mutation of the FAT2 gene in spinal meningioma

Genshu Tate, Koji Kishimoto, Toshiyuki Mitsuya
Pages: 3393-3396
Published online on: 30 August 2016

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Article

Downregulated microRNA-26a modulates prostate cancer cell proliferation and apoptosis by targeting COX-2

Jing Zhang, Jinghao Liang, Jianguo Huang
Pages: 3397-3402
Published online on: 31 August 2016

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Article

Ubenimex enhances the radiosensitivity of renal cell carcinoma cells by inducing autophagic cell death

Shuai Liu, Xiaoqing Wang, Jiaju Lu, Liping Han, Yongfei Zhang, Zheng Liu, Sentai Ding, Zhao Liu, Dongbin Bi, Zhihong Niu
Pages: 3403-3410
Published online on: 22 August 2016

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Article

Surgical treatment of rare giant malignant tumors of the scalp: A report of 3 cases with different tumor types

Xiaoliang Liu, Wenzhong Li, Hepei Yuan, Weihong Gu, Dawei Chen
Pages: 3411-3416
Published online on: 09 September 2016

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Article

Pituicytoma: A report of three cases and literature review

Xiaoyu Yang, Xiaoliang Liu, Wensen Li, Dawei Chen
Pages: 3417-3422
Published online on: 12 September 2016

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Article

Celastrol negatively regulates cell invasion and migration ability of human osteosarcoma via downregulation of the PI3K/Akt/NF-κB signaling pathway in vitro

Xiaolong Yu, Qiang Wang, Xin Zhou, Changlin Fu, Ming Cheng, Runsheng Guo, Hucheng Liu, Bin Zhang, Min Dai
Pages: 3423-3428
Published online on: 26 August 2016

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Article

Expression of aldehyde dehydrogenase family 1 member A1 and high mobility group box 1 in oropharyngeal squamous cell carcinoma in association with survival time

Xu Qian, Annekatrin Coordes, Andreas M. Kaufmann, Andreas E. Albers
Pages: 3429-3434
Published online on: 07 September 2016

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Article

SIX1 is overexpressed in endometrial carcinoma and promotes the malignant behavior of cancer cells through ERK and AKT signaling

Xiaochuan Xin, Yue Li, Xianghong Yang
Pages: 3435-3440
Published online on: 07 September 2016

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Article Open Access

Influence of ezrin-shRNA in combination with HSP70 on the apoptosis and proliferation of osteosarcoma cells

Qin Yao, Yihua Pei, Huiqin Zhuo, Bozhen Xie
Pages: 3441-3448
Published online on: 08 September 2016

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Article

The relationship between tumor volume changes and serial plasma osteopontin detection during radical radiotherapy of non-small-cell lung cancer

Christian Ostheimer, Franziska Schweyer, Thomas Reese, Matthias Bache, Dirk Vordermark
Pages: 3449-3456
Published online on: 08 September 2016

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Article

MicroRNA-150 upregulation reduces osteosarcoma cell invasion and metastasis by downregulating Ezrin

Ce Zhan, Cheng Li, Hao Zhang, Hao Tang, Fang Ji, Su‑Chi Qiao, Wei‑Dong Xu, Zhi‑Wei Wang
Pages: 3457-3462
Published online on: 25 August 2016

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Article

Inhibition of PTTG1 expression by microRNA suppresses proliferation and induces apoptosis of malignant glioma cells

Xing Su, Jianguo Chen, Lanchun Ni, Wei Shi, Jinlong Shi, Xiaojiang Liu, Yu Zhang, Peipei Gong, Hui Zhu, Qingfeng Huang
Pages: 3463-3471
Published online on: 22 August 2016

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Case Report

Conversion of aspergilloma to chronic necrotizing pulmonary aspergillosis following treatment with sunitinib: A case report

Yeon Wook Kim, Hyun Woo Lee, Jaeyoung Cho, Han‑Sol Choi, Jungsil Lee, Sung Soo Park, Eun Young Heo, Kwang Nam Jin, Deog Kyeom Kim
Pages: 3472-3474
Published online on: 26 August 2016

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Case Report

Synchronous papillary urothelial carcinoma of the bladder and squamous cell carcinoma with sarcomatoid differentiation: A case report

Mahizer Yaldiz, Nur Cihan Cosansu, Berna Solak, Zeynep Kahyaoglu, Mustafa Teoman Erdem
Pages: 3475-3477
Published online on: 30 August 2016

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Article

Acute effect of lactic acid on tumor-endothelial cell metabolic coupling in the tumor microenvironment

Guanqun Zhu, Degui Wang, Shenqian Li, Xuecheng Yang, Yanwei Cao, Yonghua Wang, Haitao Niu
Pages: 3478-3484
Published online on: 26 August 2016

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Article Open Access

PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition

Shuanhu Wang, Chenglong Li, Wenbin Wang, Chungen Xing
Pages: 3485-3491
Published online on: 21 October 2016

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Article

Clinical implication of Tiam1 overexpression in the prognosis of patients with serous ovarian carcinoma

Huiwen Li, Xuelian Cui, Dingbao Chen, Yang Yang, Junjie Piao, Zhenhua Lin, Guanghai Yan, Danhua Shen
Pages: 3492-3498
Published online on: 05 September 2016

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Article

Notch4 inhibition reduces migration and invasion and enhances sensitivity to docetaxel by inhibiting Akt/fascin in pancreatic cancer cells

Cui‑Juan Qian, Yi‑Yi Chen, Xin Zhang, Fu‑Qiang Liu, Ting‑Ting Yue, Bei Ye, Jun Yao
Pages: 3499-3505
Published online on: 07 September 2016

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Article

Tumor necrosis factor α-induced protein 8-like 1 promotes apoptosis by regulating B-cell leukemia/lymphoma-2 family proteins in RAW264.7 cells

Yinan Wang, Yao Liu, Chunfang Hu, Xiaoyan Ni, Xiaobo Huang
Pages: 3506-3512
Published online on: 05 September 2016

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Article

Thymosin α1 therapy subsequent to radical hepatectomy in patients with hepatitis B virus-associated hepatocellular carcinoma: A retrospective controlled study

Yong‑Rong Liang, Zhe Guo, Jing‑Hang Jiang, Bang‑De Xiang, Le‑Qun Li
Pages: 3513-3518
Published online on: 12 September 2016

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Article

Oleanolic acid suppresses vascular smooth muscle cell proliferation by increasing lincRNA-p21 expression

Di Han, Xuejuan Zhang, Jietao Zhang, Xiaozi Guo, Yu Zheng, Shihua Sui, Jiaping Zheng
Pages: 3519-3522
Published online on: 06 September 2016

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Article

Chromosome 16q genes CDH1, CDH13 and ADAMTS18 are correlated and frequently methylated in human lymphoma

Lobna Alkebsi, Hiroshi Handa, Akihiko Yokohama, Takayuki Saitoh, Norifumi Tsukamoto, Hirokazu Murakami
Pages: 3523-3530
Published online on: 09 September 2016

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Article

miR-223 decreases cell proliferation and enhances cell apoptosis in acute myeloid leukemia via targeting FBXW7

Yi Xiao, Changliang Su, Taoran Deng
Pages: 3531-3536
Published online on: 09 September 2016

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Article

Anticancer effect of icaritin inhibits cell growth of colon cancer through reactive oxygen species, Bcl‑2 and cyclin D1/E signaling

Chaofeng Li, Weichao Peng, Xin Song, Qian Wang, Wenyue Wang
Pages: 3537-3542
Published online on: 05 September 2016

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Article

miR-520e regulates cell proliferation, apoptosis and migration in breast cancer

Ming Yi, Minghua Li, Xia Long, Jing Ye, Junwei Cui, Wei Wei, Huijuan Wan, Meijun Yin, Shuying Gao, Zhengming Su, Fangting Zhang
Pages: 3543-3548
Published online on: 05 September 2016

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Article

Differences in tumor stroma derived from irradiated versus non-irradiated fibroblasts in a co-culture model with head and neck squamous cell carcinoma

Thomas Gehrke, Agmal Scherzad, Stephan Hackenberg, Philipp Schendzielorz, Rudolf Hagen, Norbert Kleinsasser
Pages: 3549-3554
Published online on: 01 September 2016

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Article

Management of pediatric head and neck rhabdomyosarcoma: A case-series of 36 patients

Joanna Radzikowska, Wojciech Kukwa, Andrzej Kukwa, Anna M. Czarnecka, Maciej Kawecki, Fei Lian, Cezary Szczylik, Antoni Krzeski
Pages: 3555-3562
Published online on: 01 September 2016

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Article

Long term results of hepatic resection or orthotopic liver transplantation in patients with liver metastases from gastrointestinal neuroendocrine tumors

Enrico Maria Pasqual, Serena Bertozzi, Ambrogio P. Londero, Stefano Bacchetti, Dario Lorenzin, Alberto Pasqualucci, Federico Moccheggiani, Alen Federici, Marco Vivaverlli, Andrea Risaliti
Pages: 3563-3570
Published online on: 25 August 2016

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Article

Antitumor effects and mechanisms of Ganoderma extracts and spores oil

Chun Chen, Peng Li, Ye Li, Guan Yao, Jian‑Hua Xu
Pages: 3571-3578
Published online on: 29 August 2016

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Article

Networks analysis of genes and microRNAs in human Wilms' tumors

Jimin He, Xiaoxin Guo, Linlin Sun, Kuhao Wang, Haiying Yao
Pages: 3579-3585
Published online on: 07 September 2016

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Article

Triptolide exerts pro-apoptotic and cell cycle arrest activity on drug-resistant human lung cancer A549/Taxol cells via modulation of MAPK and PI3K/Akt signaling pathways

Chen Qiong Xie, Ping Zhou, Jian Zuo, Xiang Li, Yong Chen, Jian Wei Chen
Pages: 3586-3590
Published online on: 07 September 2016

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Article

Immunohistochemical expression and serum level of survivin protein in colorectal cancer patients

Katarzyna Jakubowska, Anna Pryczynicz, Violetta Dymicka‑Piekarska, Waldemar Famulski, Katarzyna Guzińska‑Ustymowicz
Pages: 3591-3597
Published online on: 01 September 2016

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Article

Antitumor activity of 7RH, a discoidin domain receptor 1 inhibitor, alone or in combination with dasatinib exhibits antitumor effects in nasopharyngeal carcinoma cells

Qiu‑Ping Lu, Wen‑Dan Chen, Jie‑Ren Peng, Yao‑Dong Xu, Qian Cai, Gong‑Kan Feng, Ke Ding, Xiao‑Feng Zhu, Zhong Guan
Pages: 3598-3608
Published online on: 05 September 2016

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Article

Second-look surgery following Hartmann's procedure for obstructive left-sided colorectal cancer

Naohito Beppu, Fumihiko Kimura, Nagahide Matsubara, Masashi Noda, Naohiro Tomita, Hidenori Yanagi, Naoki Yamanaka
Pages: 3609-3613
Published online on: 05 September 2016

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Article

Plumbagin inhibits cell proliferation and promotes apoptosis in multiple myeloma cells through inhibition of the PI3K/Akt-mTOR pathway

Hongwei Wu, Xiaozhen Dai, Enren Wang
Pages: 3614-3618
Published online on: 26 August 2016

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Article

MicroRNA-133b inhibits the migration and invasion of non small cell lung cancer cells via targeting FSCN1 Retraction in /10.3892/ol.2021.12929

Xucheng Yang, Pengfei Lei, Yong Huang, Zijian Zhang, Yingying Zhang
Pages: 3619-3625
Published online on: 25 August 2016

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Article

Proliferation and metastatic potential of endometrial cancer cells in response to metformin treatment in a high versus normal glucose environment

Amanda de Barros Machado, Vania dos Reis, Sebastian Weber, Julia Jauckus, Ilma Simoni Brum, Helena von Eye Corleta, Thomas Strowitzki, Edison Capp, Ariane Germeyer
Pages: 3626-3632
Published online on: 23 August 2016

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Article

MicroRNA-138 inhibits proliferation, migration and invasion through targeting hTERT in cervical cancer

Na Zhou, Dan Fei, Shan Zong, Mingyue Zhang, Ying Yue
Pages: 3633-3639
Published online on: 23 August 2016

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Article

Regulatory network of microRNAs and genes in testicular cancer

Yansong Zhao, Zhiwen Xu, Ning Wang, Shang Wang
Pages: 3640-3646
Published online on: 24 August 2016

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Review

Toll-like receptors and cutaneous melanoma (Review)

Ilaria Coati, Serena Miotto, Irene Zanetti, Mauro Alaibac
Pages: 3655-3661
Published online on: 21 September 2016

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Review

Molecular alterations in the carcinogenesis and progression of hepatocellular carcinoma: Tumor factors and background liver factors (Review)

Yoshikuni Inokawa, Kenichi Inaoka, Fuminori Sonohara, Masamichi Hayashi, Mitsuro Kanda, Shuji Nomoto
Pages: 3662-3668
Published online on: 15 September 2016

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Review Open Access

Sensitization strategies in lung cancer (Review) Retraction in /10.3892/ol.2025.15198

Xiao‑Ying Zhang, Peiying Zhang
Pages: 3669-3673
Published online on: 16 September 2016

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Review Open Access

Recent perspectives of breast cancer prognosis and predictive factors (Review)

Su‑Sheng Cao, Cun‑Tao Lu
Pages: 3674-3678
Published online on: 19 September 2016

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Article Open Access

Receptor tyrosine kinases in carcinogenesis (Review) Retraction in /10.3892/ol.2020.12062

Xiao-Ying Zhang, Pei-Ying Zhang
Pages: 3679-3682
Published online on: 28 September 2016

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Article Open Access

Scorpion venoms in gastric cancer (Review) Retraction in /10.3892/ol.2020.12063

Xiao-Ying Zhang, Pei-Ying Zhang
Pages: 3683-3686
Published online on: 14 September 2016

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Case Report Open Access

Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review

Yaonan Zhang, Zongyang Qu, Fang Fang
Pages: 3687-3694
Published online on: 27 September 2016

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Article Open Access

Inhibition of cell proliferation and tumor growth of colorectal cancer by inhibitors of Wnt and Notch signaling pathways

Yuliang Xiao, Xiaojing Yang, Yinglei Miao, Xikun He, Ming Wang, Weihong Sha
Pages: 3695-3700
Published online on: 22 September 2016

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Article Open Access

In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao‑Bei Cai, Zhang Zhang, Rui Wei
Pages: 3701-3706
Published online on: 26 September 2016

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Article Open Access

Effect of surgical wound fluids after intraoperative electron radiotherapy on the cancer stem cell phenotype in a panel of human breast cancer cell lines

Karolina Zaleska, Wiktoria Maria Suchorska, Anna Przybyła, Dawid Murawa
Pages: 3707-3714
Published online on: 21 September 2016

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Article Open Access

Expression and survival significance of B-cell-specific Moloney murine leukemia virus integration site 1 and matrix metalloproteinase-9 in non-small-cell lung cancer

Mingkui Mu, Yang Song, Bin Zhang
Pages: 3715-3722
Published online on: 29 September 2016

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Article Open Access

Cisplatin-induced regulation of signal transduction pathways and transcription factors in p53-mutated subclone variants of hepatoma cells: Potential application for therapeutic targeting

Jinn‑Rung Kuo, Hung‑Sheng Shang, Chun‑Te Ho, Kun‑Goung Lai, Tsan‑Zon Liu, Yin‑Ju Chen, Jeng‑Fong Chiou
Pages: 3723-3730
Published online on: 23 September 2016

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Article Open Access

Expression profile of SPACA5/Spaca5 in spermatogenesis and transitional cell carcinoma of the bladder

Xiao‑Yue Zhang, Qiu‑Xia Yan, Xiao‑Yan Guo, Cai‑Rong Chen, Run‑Qiang Chen, Zhi‑Ming Cai, Ai‑Fa Tang
Pages: 3731-3738
Published online on: 21 September 2016

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Article Open Access

EHHM, a novel phenolic natural product from Livistona chinensis, induces autophagy-related apoptosis in hepatocellular carcinoma cells

Xinsheng Cheng, Feng Zhong, Kun He, Shibo Sun, Hongbo Chen, Jie Zhou
Pages: 3739-3748
Published online on: 22 September 2016

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Article Open Access

Adenovirus‑mediated interleukin 21 gene transfer enhances antitumor immunity and reduces tumorigenicity of Hepa1‑6 in mice

Jiyu Ju, Lina Wang, Dalin Di, Weiling Xiao, Meiyu Peng, Yishuai Liu, Xiaoyan Fu, Chunling Zhao, Xuebin Qin
Pages: 3749-3754
Published online on: 15 September 2016

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Article Open Access

Deficiency of SUMO-specific protease 1 induces arsenic trioxide-mediated apoptosis by regulating XBP1 activity in human acute promyelocytic leukemia

Fei‑Fei Wang, Ming‑Zhu Liu, Yi Sui, Qing Cao, Bo Yan, Mei‑Ling Jin, Xi Mo
Pages: 3755-3762
Published online on: 21 September 2016

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Article Open Access

Quantitative contrast-enhanced ultrasonography for the differential diagnosis of endometrial hyperplasia and endometrial neoplasms

Ying Liu, Yi Xu, Wen Cheng, Xinghan Liu
Pages: 3763-3770
Published online on: 29 September 2016

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Article Open Access

Celastrus orbiculatus extract triggers apoptosis and autophagy via PI3K/Akt/mTOR inhibition in human colorectal cancer cells

Lin Yang, Yanqing Liu, Mei Wang, Yayun Qian, Xiaojun Dai, Yaodong Zhu, Jue Chen, Shiyu Guo, Tadashi Hisamitsu
Pages: 3771-3778
Published online on: 29 September 2016

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Article Open Access

Osthole induces lung cancer cell apoptosis through inhibition of inhibitor of apoptosis family proteins

Xiao‑Man Xu, Man‑Li Zhang, Yi Zhang, Li Zhao
Pages: 3779-3784
Published online on: 22 September 2016

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Article Open Access

Advantages and disadvantages of F-18 fluorodeoxyglucose positron emission tomography/computed tomography in carcinoma of unknown primary

Xiaozhou Yu, Xiaofeng Li, Xiuyu Song, Dong Dai, Lei Zhu, Yanjia Zhu, Jian Wang, Huiqin Zhao, Wengui Xu
Pages: 3785-3792
Published online on: 29 September 2016

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Article Open Access

Effect of matrine combined with cisplatin on the expression of XIAP in human rhabdomyosarcoma RD cells

Li Li, Tianyang Xue, Wei Xu, Bin Zhou
Pages: 3793-3798
Published online on: 19 September 2016

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Article Open Access

Improved laparoscopic nephron-sparing surgery for renal cell carcinoma based on the precise anatomy of the nephron

Gang Guo, Wei Cai, Xu Zhang
Pages: 3799-3803
Published online on: 21 September 2016

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Article Open Access

Periostin and tumor-stroma interactions in non-small cell lung cancer

Ulrich Nitsche, Daniela Stangel, Zheng Pan, Anna Melissa Schlitter, Irene Esposito, Ivonne Regel, Susanne Raulefs, Helmut Friess, Jörg Kleeff, Mert Erkan
Pages: 3804-3810
Published online on: 14 September 2016

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Article Open Access

Crk-like adapter protein is overexpressed in cervical carcinoma, facilitates proliferation, invasion and chemoresistance, and regulates Src and Akt signaling

Hong Ji, Bo Li, Shitai Zhang, Zheng He, Yang Zhou, Ling Ouyang
Pages: 3811-3817
Published online on: 21 September 2016

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Article Open Access

Effect of silencing SATB1 on proliferation, invasion and apoptosis of A549 human lung adenocarcinoma cells

Bo Huang, Hongli Zhou, Siwang Wang, Xian Ping Lang, Xiaodong Wang
Pages: 3818-3824
Published online on: 22 September 2016

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Article Open Access

High PARP-1 expression is associated with tumor invasion and poor prognosis in gastric cancer

Ying Liu, Yu Zhang, Ying Zhao, Dongna Gao, Jing Xing, Hui Liu
Pages: 3825-3835
Published online on: 22 September 2016

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Article Open Access

Cyclooxygenase-2 is associated with malignant phenotypes in human lung cancer

Weiying Li, Wentao Yue, Hui Wang, Baitang Lai, Xuehui Yang, Chunyan Zhang, Yue Wang, Meng Gu
Pages: 3836-3844
Published online on: 29 September 2016

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Article Open Access

Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis

Afsoon Taghavi, Mohammad Esmaeil Akbari, Mohammad Hashemi‑Bahremani, Nahid Nafissi, Ahad Khalilnezhad, Seyed Mohammad Poorhosseini, Feyzollah Hashemi‑Gorji, Vahid Reza Yassaee
Pages: 3845-3855
Published online on: 30 September 2016

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Case Report Open Access

Letrozole as second-line hormonal treatment for recurrent low-grade endometrial stromal sarcoma: A case report and review of the literature

Kohei Nakamura, Kentaro Nakayama, Masako Ishikawa, Noriyoshi Ishikawa, Hiroshi Katagiri, Atsuko Katagiri, Tomoka Ishibashi, Emi Sato, Kohji Iida, Razia Sultana, Satoru Kyo
Pages: 3856-3860
Published online on: 26 September 2016

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Article Open Access

The prognostic significance of estrogen receptor β in head and neck squamous cell carcinoma

Kresimir Grsic, Iva Ledinsky Opacic, Sanda Sitic, Marija Milkovic Perisa, Petar Suton, Bozena Sarcevic
Pages: 3861-3865
Published online on: 15 September 2016

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Article Open Access

Comparative analysis of gene expression profiles of gastric cardia adenocarcinoma and gastric non-cardia adenocarcinoma

Bin Song, Juan Du, Neng Deng, Ji‑Chen Ren, Zhen‑Bo Shu
Pages: 3866-3874
Published online on: 21 September 2016

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Article Open Access

Diagnosis of pancreatic lesions collected by endoscopic ultrasound-guided fine-needle aspiration using next-generation sequencing

Eri Kameta, Kazuya Sugimori, Takashi Kaneko, Tomohiro Ishii, Haruo Miwa, Takeshi Sato, Yasuaki Ishii, Soichiro Sue, Tomohiko Sasaki, Yuki Yamashita, Wataru Shibata, Naomichi Matsumoto, Shin Maeda
Pages: 3875-3881
Published online on: 21 September 2016

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Article Open Access

Identification of targets of miRNA-221 and miRNA-222 in fulvestrant-resistant breast cancer

Pengfei Liu, Manna Sun, Wenhua Jiang, Jinkun Zhao, Chunyong Liang, Huilai Zhang
Pages: 3882-3888
Published online on: 23 September 2016

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Article Open Access

Evaluation of the association between HIF-1α and HER-2 expression, hormone receptor status, Ki-67 expression, histology and tumor FDG uptake in breast cancer

Sevi̇m Sureyya Cerci, Kemal Kursat Bozkurt, Hasan Erol Eroglu, Celal Cerci, Evri̇m Erdemoglu, Pinar Talip Bulbul, Meltem Cetin, Recep Cetin, Ibrahim Metin Ciris, Mahmut Bulbul
Pages: 3889-3895
Published online on: 28 September 2016

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Article Open Access

RNAi-mediated gene silencing of vascular endothelial growth factor C suppresses growth and induces apoptosis in mouse breast cancer in vitro and in vivo

Yong‑Chao Liu, Wen‑Hui Ma, Yin‑Lin Ge, Mei‑Lan Xue, Zheng Zhang, Jin‑Yu Zhang, Lin Hou, Run‑Hong Mu
Pages: 3896-3904
Published online on: 21 September 2016

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Article Open Access

Overexpression of microRNA‑24 increases the sensitivity to paclitaxel in drug‑resistant breast carcinoma cell lines via targeting ABCB9

Jian‑Ping Gong, Liu Yang, Jun‑Wei Tang, Peng Sun, Qing Hu, Jian‑Wei Qin, Xiao‑Ming Xu, Bei‑Cheng Sun, Jin‑Hai Tang
Pages: 3905-3911
Published online on: 15 September 2016

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Article Open Access

Serum miR‑300 as a diagnostic and prognostic biomarker in osteosarcoma

Jian‑Dong Liu, Qun Xin, Chun‑Sheng Tao, Pei‑Feng Sun, Peng Xu, Bing Wu, Liang Qu, Shu-Zhong Li
Pages: 3912-3918
Published online on: 29 September 2016

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Article Open Access

A single-center retrospective study of pediatric hepatoblastoma

Yi Zhang, Weiling Zhang, Suoqin Tang, Liping Chen, You Yi, Pinwei Zhang, Aiping Liu, Tian Zhi, Dongsheng Huang
Pages: 3919-3925
Published online on: 27 September 2016

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Article Open Access

MicroRNA-298 inhibits malignant phenotypes of epithelial ovarian cancer by regulating the expression of EZH2

Fenmei Zhou, Juan Chen, Hairong Wang
Pages: 3926-3932
Published online on: 29 September 2016

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Article Open Access

Value of window technique in diagnosis of the ground glass opacities in patients with non-small cell pulmonary cancer

Gang Yao
Pages: 3933-3935
Published online on: 14 September 2016

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Article Open Access

Expression of GOLPH3 protein in colon cancer tissues and its association with the prognosis of patients

Bo Zhou, Gongping Wang, Shegan Gao, Ye Chen, Canhui Jin, Zengfang Wang, Yantong Yang, Zhikun Ma, Wei Zhang, Xiaoshan Feng
Pages: 3936-3940
Published online on: 29 September 2016

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Article Open Access

Drug resistance analysis of gefitinib-targeted therapy in non-small cell lung cancer

Shuliang Liu, Hongji Yang, Xingping Ge, Lingfei Su, Aifeng Zhang, Liang Liang
Pages: 3941-3943
Published online on: 22 September 2016

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Article Open Access

Evaluation of the efficacy of paclitaxel with curcumin combination in ovarian cancer cells

Zeng Liu, Yuan-Yuan Zhu, Zhao-Yuan Li, Si-Qing Ning
Pages: 3944-3948
Published online on: 26 September 2016

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Article

Inhibitory effects of Chinese nutritional herbs in isogenic breast carcinoma cells with modulated estrogen receptor function

Nitin Telang, Guo Li, Meena Katdare, Daniel Sepkovic, Leon Bradlow, George Wong
Pages: 3949-3957
Published online on: 28 September 2016

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Article

Role of microRNA-4458 in patients with non-small-cell lung cancer

Lidao Bao, Linlin Wang, Guomin Wei, Yuehong Wang, Gerile Wuyun, Agula Bo
Pages: 3958-3966
Published online on: 22 September 2016

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Article

Expression of semaphorin 6D and its receptor plexin-A1 in gastric cancer and their association with tumor angiogenesis

Yanjie Lu, Qian Xu, Lei Chen, Yanzhen Zuo, Shaochen Liu, Yatao Hu, Xiaoru Li, Yuhong Li, Xiangyang Zhao
Pages: 3967-3974
Published online on: 29 September 2016

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Article

Metaplastic carcinoma of the breast: Imaging and pathological features

Tiantian Bian, Qing Lin, Zengjie Wu, Chunxiao Cui, Chunhua Qi, Li Li, Xiaohui Su
Pages: 3975-3980
Published online on: 22 September 2016

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Case Report

Globose, cystic olfactory ensheathing cell tumor: A case report and literature review

Yaoling Liu, Minghai Wei, Kang Yang, Zeshi Tan, Xu Sun, Xinyu Li, Ningwei Che, Lan Luan, Guanyu Wang, Xiaofeng Wang, Yuqiang Sun, Jian Yin
Pages: 3981-3986
Published online on: 14 September 2016

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Article

Prioritization of non-coding disease-causing variants and long non-coding RNAs in liver cancer

Hua Li, Zekun He, Yang Gu, Lin Fang, Xin Lv
Pages: 3987-3994
Published online on: 14 September 2016

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Article

C5a receptor expression is associated with poor prognosis in urothelial cell carcinoma patients treated with radical cystectomy or nephroureterectomy

Yoshihiro Wada, Yoshihiro Maeda, Tatsuko Kubo, Ken Kikuchi, Masatoshi Eto, Takahisa Imamura
Pages: 3995-4000
Published online on: 15 September 2016

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Case Report

Primary renal lymphoma: A case report and literature review

Xiaodong Chen, Danfei Hu, Laifu Fang, Yichen Chen, Xiaohang Che, Jin Tao, Guobin Weng, Xiaolei Ye
Pages: 4001-4008
Published online on: 22 September 2016

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Case Report

Small cell lung cancer transformation and the T790M mutation: A case report of two acquired mechanisms of TKI resistance detected in a tumor rebiopsy and plasma sample of EGFR-mutant lung adenocarcinoma

Greta Alì, Rossella Bruno, Mirella Giordano, Irene Prediletto, Letizia Marconi, Simonetta Zupo, Franco Fedeli, Alessandro Ribechini, Antonio Chella, Gabriella Fontanini
Pages: 4009-4012
Published online on: 26 September 2016

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Article

Mitofusin-2 prevents skeletal muscle wasting in cancer cachexia

Qiu‑Lei Xi, Bo Zhang, Yi Jiang, Hai‑Sheng Zhang, Qing‑Yang Meng, Ying Chen, Yu‑Song Han, Qiu‑Lin Zhuang, Jun Han, Hai‑Yu Wang, Jing Fang, Guo‑Hao Wu
Pages: 4013-4020
Published online on: 26 September 2016

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Article

Decreased expression of the CHD5 gene and its clinicopathological significance in breast cancer: Correlation with aberrant DNA methylation

Zhongliang Ma, Jinlian Song, Simin Liu, Linlin Han, Yangping Chen, Yaqiu Wang, Chundong Yu, Lin Hou
Pages: 4021-4026
Published online on: 16 September 2016

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Article

Primary mesenchymal tumors of the pancreas in a single center over 15 years

Hongkai Zhang, Shuangni Yu, Wenze Wang, Yin Cheng, Yu Xiao, Zhaohui Lu, Jie Chen
Pages: 4027-4034
Published online on: 20 September 2016

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Article

A promoter polymorphism in the hMLH1 gene (-93G/A) associated with sporadic colorectal cancer

Li‑Li Zhang, Xue‑Jun Tang, Xiao‑Yun Wang, Ying‑Wei Zhu, Xiao‑Bin Peng, Lei Gong
Pages: 4035-4040
Published online on: 26 September 2016

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Article

Role of miR-196 and its target gene HoxB8 in the development and proliferation of human colorectal cancer and the impact of neoadjuvant chemotherapy with FOLFOX4 on their expression

Songfei Shen, Jie Pan, Xingrong Lu, Pan Chi
Pages: 4041-4047
Published online on: 29 September 2016

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Case Report

Unusual lower back pain with monocytosis: A case report

Sheng‑Cheng Wu, Tzu‑Chuan Huang, Wen‑Ya Yu, Yi‑Ying Wu
Pages: 4048-4050
Published online on: 26 September 2016

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Case Report

Classical intracranial chondrosarcoma: A case report

Jingyang Chi, Mingchao Zhang, Jianmin Kang
Pages: 4051-4053
Published online on: 20 September 2016

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Article

Co-culture of hepatoma cells with hepatocytic precursor (stem-like) cells inhibits tumor cell growth and invasion by downregulating Akt/NF-κB expression

Cheng‑Jun Sui, Miao Xu, Wei‑Qing Li, Jia‑Mei Yang, Hong‑Zhu Yan, Hui‑Min Liu, Chun‑Yan Xia, Hong‑Yu Yu
Pages: 4054-4060
Published online on: 13 September 2016

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Article

HOTAIR, a long non-coding RNA driver of malignancy whose expression is activated by FOXC1, negatively regulates miRNA-1 in hepatocellular carcinoma

Dong‑Na Su, Shi‑Pin Wu, Hong‑Tao Chen, Jin‑Hua He
Pages: 4061-4067
Published online on: 13 September 2016

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Article

Dysregulation of long non‑coding RNA profiles in human colorectal cancer and its association with overall survival

Lei Yang, Lingling Xu, Qian Wang, Min Wang, Guangyu An
Pages: 4068-4074
Published online on: 15 September 2016

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Article

A case of distal extrahepatic cholangiocarcinoma with two positive resection margins

Wayne A. Warner, Wesley Ramcharan, Dave Harnanan, Srikanth Umakanthan, Ravi Maharaj
Pages: 4075-4079
Published online on: 22 September 2016

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Article

High expression of CD39 in gastric cancer reduces patient outcome following radical resection

Xiao‑Yan Cai, Xue‑Fei Wang, Jun Li, Jiang‑Nan Dong, Jiang‑Qi Liu, Neng‑Ping Li, Bei Yun, Rong‑Long Xia, Jing Qin, Yi‑Hong Sun
Pages: 4080-4086
Published online on: 26 September 2016

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Article

Establishment of specific cytotoxic T lymphocyte culture system and its inhibitory effect on ovarian cancer

Mingxing Sui, Lihui Si, Tianmin Xu, Manhua Cui
Pages: 4087-4093
Published online on: 28 September 2016

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Article

Cryptotanshinone inhibits lung tumor growth by increasing CD4+ T cell cytotoxicity through activation of the JAK2/STAT4 pathway

Yonghong Man, Le Yang, Dongxian Zhang, Yongyi Bi
Pages: 4094-4098
Published online on: 12 September 2016

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Article

Regulatory network analysis of genes and microRNAs in human hepatoblastoma

Jimin He, Xiaoxin Guo, Linlin Sun, Ning Wang, Jiwei Bao
Pages: 4099-4106
Published online on: 27 September 2016

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Article

Potential impact of mTOR inhibitors on cervical squamous cell carcinoma: A systematic review

Daniele Xavier Assad, Silvia Taveira Elias, Andréia Cristina Melo, Carlos Gil Ferreira, Graziela De Luca Canto, Eliete Neves Silva Guerra
Pages: 4107-4116
Published online on: 20 September 2016

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Article

Curcumin potentiates the effect of chemotherapy against acute lymphoblastic leukemia cells via downregulation of NF‑κB

Helia Judith Pimentel-Gutiérrez, Lucina Bobadilla-Morales, César Cenobio Barba-Barba, Citlalli Ortega-De-La-Torre, Fernando Antonio Sánchez-Zubieta, Jorge Román Corona-Rivera, Betsy Annel González-Quezada, Juan S. Armendáriz-Borunda, Rocío Silva-Cruz, Alfredo Corona-Rivera
Pages: 4117-4124
Published online on: 30 September 2016

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Article

9-AAA inhibits growth and induces apoptosis in human melanoma A375 and rat prostate adenocarcinoma AT‑2 and Mat-LyLu cell lines but does not affect the growth and viability of normal fibroblasts

Włodzimierz Korohoda, Anna Hapek, Monika Pietrzak, Damian Ryszawy, Zbigniew Madeja
Pages: 4125-4132
Published online on: 28 September 2016

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Article

Expression of MMP9, SERPINE1 and miR‑134 as prognostic factors in esophageal cancer

Anna Agnieszka Klimczak‑Bitner, Radzisław Kordek, Jan Bitner, Jacek Musiał, Janusz Szemraj
Pages: 4133-4138
Published online on: 29 September 2016

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Article

Curcumin suppresses colon cancer cell invasion via AMPK-induced inhibition of NF-κB, uPA activator and MMP9

Weihua Tong, Quan Wang, Donghui Sun, Jian Suo
Pages: 4139-4146
Published online on: 16 September 2016

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Article

Resveratrol reverses P-glycoprotein-mediated multidrug resistance of U2OS/ADR cells by suppressing the activation of the NF-κB and p38 MAPK signaling pathways Corrigendum in /10.3892/ol.2024.14225

Rui Zhang, Ming Lu, Zhen Zhang, Xiliang Tian, Shouyu Wang, Decheng Lv
Pages: 4147-4154
Published online on: 14 September 2016

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Article

Expression and clinicopathological significance of the lncRNA HOXA11-AS in colorectal cancer

Tong Li, Chengfei Xu, Bin Cai, Meng Zhang, Feng Gao, Jialiang Gan
Pages: 4155-4160
Published online on: 14 September 2016

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Article

Sprouty4 mRNA variants and protein expressions in breast and lung‑derived cells

Angelina Doriguzzi, Jihen Salhi, Hedwig Sutterlüty‑Fall
Pages: 4161-4166
Published online on: 30 September 2016

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Article

Runx2 expression: A mesenchymal stem marker for cancer

Maria Teresa Valenti, Paola Serafini, Giulio Innamorati, Anna Gili, Samuele Cheri, Claudio Bassi, Luca Dalle Carbonare
Pages: 4167-4172
Published online on: 23 September 2016

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Article

Effects of microRNA-21 on the biological functions of T-cell acute lymphoblastic lymphoma/leukemia

Cunzhen Shi, Xudong Zhang, Xin Li, Lei Zhang, Ling Li, Zhenchang Sun, Xiaorui Fu, Jingjing Wu, Yu Chang, Wencai Li, Qingjiang Chen, Mingzhi Zhang
Pages: 4173-4180
Published online on: 21 September 2016

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Article

MicroRNA-181b is downregulated in non-small cell lung cancer and inhibits cell motility by directly targeting HMGB1

Yun Liu, Xu Hu, Daokui Xia, Songlin Zhang
Pages: 4181-4186
Published online on: 28 September 2016

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Article

Corosolic acid inhibits the proliferation of osteosarcoma cells by inducing apoptosis

Yong Jia, Hua Yuan, Shouqin Shan, Gang Xu, Jie Yu, Chenguang Zhao, Xiang Mou
Pages: 4187-4194
Published online on: 26 September 2016

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Article

Nedaplatin enhanced apoptotic effects of ABT-737 in human cancer cells via Mcl-1 inhibition

Chong Zhang, Yang‑Ling Li, Xu Weng, Li‑Yan Li, Ming‑Xian Zhou, Da‑Yong Zhang, Neng‑Ming Lin
Pages: 4195-4202
Published online on: 20 September 2016

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Article

MicroRNA-199a-5p inhibits cisplatin-induced drug resistance via inhibition of autophagy in osteosarcoma cells

Yusheng Li, Wei Jiang, Yuling Hu, Zixun Da, Chao Zeng, Min Tu, Zhenhan Deng, Wenfeng Xiao
Pages: 4203-4208
Published online on: 22 September 2016

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Article

Evaluation of recurrent disease in the re-staging of colorectal cancer by 18F-FDG PET/CT: Use of CEA and CA 19-9 in patient selection

Agostino Chiaravalloti, Alessandro Fiorentini, Erika Palombo, Davide Rinino, Annamaria Lacanfora, Roberta Danieli, Carmen Di Russo, Daniele Di Biagio, Ettore Squillaci, Orazio Schillaci
Pages: 4209-4213
Published online on: 15 September 2016

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Case Report

Trousseau's syndrome caused by bladder cancer producing granulocyte colony-stimulating factor and parathyroid hormone-related protein: A case report

Tomonori Kato, Kenji Yasuda, Hiroaki Iida, Akihiko Watanabe, Yasuyoshi Fujiuchi, Shigeharu Miwa, Johji Imura, Akira Komiya
Pages: 4214-4218
Published online on: 20 September 2016

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Article

Growth differentiating factor-15 (GDF-15): A potential biomarker and therapeutic target for cancer-associated weight loss

Lorena Lerner, Jeno Gyuris, Richard Nicoletti, James Gifford, Brian Krieger, Aminah Jatoi
Pages: 4219-4223
Published online on: 23 September 2016

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Article

Promotion of metastasis of thyroid cancer cells via NRP-2-mediated induction

Dom‑Gene Tu, Wen‑Wei Chang, Ming‑Shiou Jan, Chi‑Wen Tu, Yin‑Che Lu, Chien‑Kuo Tai
Pages: 4224-4230
Published online on: 20 September 2016

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Article

UGT1A1*6, UGT1A7*3 and UGT1A9*1b polymorphisms are predictive markers for severe toxicity in patients with metastatic gastrointestinal cancer treated with irinotecan-based regimens

Chengxu Cui, Chang Shu, Dandan Cao, Yi Yang, Junbao Liu, Shuping Shi, Zhujun Shao, Nan Wang, Ting Yang, Hao Liang, Shanshan Zou, Songnian Hu
Pages: 4231-4237
Published online on: 14 September 2016

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Article

Exploring the impact of EGFR T790M neighboring SNPs on ARMS-based T790M mutation assay

Sanpeng Xu, Yaqi Duan, Liping Lou, Fengjuan Tang, Juan Shou, Guoping Wang
Pages: 4238-4244
Published online on: 26 September 2016

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Article

Routine blood examinations combined with morphological analysis for the diagnosis of myelodysplastic/myeloproliferative neoplasms

Huanling Wu, Hui Sun, Zhifen Zhang, Xiangli Li, Yuantang Li, Li Li, Rui Xu, Zie Wang, Wenjun Tian
Pages: 4245-4251
Published online on: 21 September 2016

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Article

A novel curcumin analogue is a potent chemotherapy candidate for human hepatocellular carcinoma

Ji‑An Zhao, Mei‑Xiang Sang, Cui‑Zhi Geng, Shi‑Jie Wang, Bao‑En Shan
Pages: 4252-4262
Published online on: 13 September 2016

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Article

In vitro evaluation of a combination treatment involving anticancer agents and an aurora kinase B inhibitor

Senna Sakai, Hiroto Izumi, Yukiko Yoshiura, Yoshifumi Nakayama, Takahiro Yamaguchi, Yoshikazu Harada, Chiho Koi, Hiroyuki Kurata, Yasuo Morimoto
Pages: 4263-4269
Published online on: 20 September 2016

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Article

Vitamin C induces apoptosis in AGS cells via production of ROS of mitochondria

Jae Young Lim, Donghyun Kim, Bok Ran Kim, Jin Su Jun, Jung Sook Yeom, Ji Sook Park, Ji‑Hyun Seo, Chan Hoo Park, Hyang Ok Woo, Hee‑Shang Youn, Seung‑Chul Baik, Woo‑Kon Lee, Myung‑Je Cho, Kwang‑Ho Rhee
Pages: 4270-4276
Published online on: 29 September 2016

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Correction Open Access

[Corrigendum] Carcinoma-like nonfunctional pheochromocytoma in the right adrenal gland: A case report

Shingo Moriyama, Hideki Takeshita, Saori Araki, Takuo Tokairin, Makoto Kagawa, Koji Chiba, Akiko Adachi, Akira Noro
Pages: 4277-4277
Published online on: 16 September 2016

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Correction Open Access

[Corrigendum] Oncogenic role of the Notch pathway in primary liver cancer (Review)

Jie Lu, Yujing Xia, Kan Chen, Yuanyuan Zheng, Jianrong Wang, Wenxia Lu, Qin Yin, Fan Wang, Yingqun Zhou, Chuanyong Guo
Pages: 4278-4278
Published online on: 16 September 2016

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January-2026 Volume 31 Issue 1

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CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

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SCImago Journal Rank (SJR): 0.663

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Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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Review Open Access

From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
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Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
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Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
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Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
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Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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