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Case Report Open Access

Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review

  • Authors:
    • Yaonan Zhang
    • Zongyang Qu
    • Fang Fang
  • View Affiliations / Copyright

    Affiliations: Department of Orthopedics, Beijing Hospital, Beijing 100730, P.R. China, Department of Anesthesiology, Beijing Hospital, Beijing 100730, P.R. China, Department of Pathology, Beijing Hospital, Beijing 100730, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3687-3694
    |
    Published online on: September 27, 2016
       https://doi.org/10.3892/ol.2016.5194
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Abstract

Langerhans cell sarcoma (LCS) is a neoplastic proliferation of Langerhans cells with notably malignant cytological features. Reports of LCS are sparsely available in English literature; to the best of our knowledge, only 55 cases have been reported. The present study reports a case of LCS originating from subcutaneous tissue of the left knee in a 75‑year‑old man. The diagnosis of LCS was supported by the results of magnetic resonance imaging, histological and immunohistochemical studies. The tumor began to metastasize to inguinal lymph nodes and eventually involved multiple organs. Chemotherapy and radiotherapy were administered but were ineffective, and the patient died within 2 years of diagnosis. The present case should aid in expanding the currently available knowledge concerning LCS.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang Y, Qu Z and Fang F: Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review. Oncol Lett 12: 3687-3694, 2016.
APA
Zhang, Y., Qu, Z., & Fang, F. (2016). Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review. Oncology Letters, 12, 3687-3694. https://doi.org/10.3892/ol.2016.5194
MLA
Zhang, Y., Qu, Z., Fang, F."Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review". Oncology Letters 12.5 (2016): 3687-3694.
Chicago
Zhang, Y., Qu, Z., Fang, F."Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review". Oncology Letters 12, no. 5 (2016): 3687-3694. https://doi.org/10.3892/ol.2016.5194
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang Y, Qu Z and Fang F: Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review. Oncol Lett 12: 3687-3694, 2016.
APA
Zhang, Y., Qu, Z., & Fang, F. (2016). Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review. Oncology Letters, 12, 3687-3694. https://doi.org/10.3892/ol.2016.5194
MLA
Zhang, Y., Qu, Z., Fang, F."Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review". Oncology Letters 12.5 (2016): 3687-3694.
Chicago
Zhang, Y., Qu, Z., Fang, F."Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review". Oncology Letters 12, no. 5 (2016): 3687-3694. https://doi.org/10.3892/ol.2016.5194
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