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Significance of clearing differentiated thyroid carcinoma lymph node by high‑frequency color Doppler ultrasonography

  • Authors:
    • Bing Liu
    • Huadong Qin
    • Bin Zhang
    • Tiefeng Shi
    • Chuanle Li
    • Yao Liu
    • Meiyue Song
  • View Affiliations / Copyright

    Affiliations: Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China, Department of Pathology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China
    Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 253-257
    |
    Published online on: November 30, 2016
       https://doi.org/10.3892/ol.2016.5450
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Abstract

We compared the clinical effects and prognosis of patients receiving lymph node dissection after surgical removal of the thyroid tissues and those not receiving it after the removal. A total of 80 patients diagnosed with differentiated thyroid carcinoma (DTC) by our hospital from March 2012 to March 2014 were successively included in the study. The cases were divided into the control group (n=36 cases) and observation group (n=44 cases), and the two groups underwent total or subtotal resection of the thyroid. In the control group, patients underwent preoperative high‑frequency color ultrasonography, and the most suspicious lymph node was removed. In the observation group, patients underwent preoperative high‑frequency color ultrasonography, and the surgeons cleared the lymph node of the widest range. Difference in clinical effects and prognosis of the two groups were compared. After nearly a year's follow‑up observation, the tumor recurrence rate of the observation group was significantly lower than that of the control group and the survival rate of the observation group was significantly higher than that of the control group (P<0.05). The rate of surgery complications and comparative difference of the two patient groups had no statistical significance (P>0.05). When comparing the data of lymphatic metastasis tested by preoperative high‑frequency color ultrasonography with intraoperative diagnosed figures, sensitivity was 97.4%, specificity 33.3%, positive predictive value 90.2% and the negative predictive value 66.7%. In conclusion, removal of the lymph node for DTC patients having undergone thyroid tissue excision with preoperative high‑frequency color ultrasonography can be beneficial to improve the effects along with reduction in the recurrence rate.
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1 

Siegel R, Naishadham D and Jemal A: Cancer statistics, 2012. CA Cancer J Clin. 62:10–29. 2012. View Article : Google Scholar : PubMed/NCBI

2 

Carty SE, Cooper DS, Doherty GM, Duh QY, Kloos RT, Mandel SJ, Randolph GW, Stack BC Jr, Steward DL, Terris DJ, et al: American Thyroid Association Surgery Working Group; American Association of Endocrine Surgeons; American Academy of Otolaryngology-Head and Neck Surgery; American Head and Neck Society: Consensus statement on the terminology and classification of central neck dissection for thyroid cancer. Thyroid. 19:1153–1158. 2009. View Article : Google Scholar : PubMed/NCBI

3 

Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ, Mazzaferri EL, McIver B, Pacini F, Schlumberger M, et al: American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer: Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 19:1167–1214. 2009. View Article : Google Scholar : PubMed/NCBI

4 

Rotstein L: The role of lymphadenectomy in the management of papillary carcinoma of the thyroid. J Surg Oncol. 99:186–188. 2009. View Article : Google Scholar : PubMed/NCBI

5 

Yüce I, Cağli S, Bayram A, Karasu F and Güney E: Regional metastatic pattern of papillary thyroid carcinoma. Eur Arch Otorhinolaryngol. 267:437–441. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Pisello F, Geraci G, Lo Nigro C, Li Volsi F, Modica G and Sciumè C: Neck node dissection in thyroid cancer. A review. G Chir. 31:112–118. 2010.PubMed/NCBI

7 

Vergez S, Sarini J, Percodani J, Serrano E and Caron P: Lymph node management in clinically node-negative patients with papillary thyroid carcinoma. Eur J Surg Oncol. 36:777–782. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Ferlito A, Robbins KT, Silver CE, Hasegawa Y and Rinaldo A: Classification of neck dissections: An evolving system. Auris Nasus Larynx. 36:127–134. 2009. View Article : Google Scholar : PubMed/NCBI

9 

Hughes DT and Doherty GM: Central neck dissection for papillary thyroid cancer. Cancer Control. 18:83–88. 2011.PubMed/NCBI

10 

Moo TA and Fahey TJ III: Lymph node dissection in papillary thyroid carcinoma. Semin Nucl Med. 41:84–88. 2011. View Article : Google Scholar : PubMed/NCBI

11 

Clark OH: Thyroid cancer and lymph node metastases. J Surg Oncol. 103:615–618. 2011. View Article : Google Scholar : PubMed/NCBI

12 

Zhang B, Niu HM, Wu Q, Zhou J, Jiang YX, Yang X, Li JC, Zhao RN, Wang M, Li KN, et al: Comparison of clinical and ultrasonographic features of poorly differentiated thyroid carcinoma and papillary thyroid carcinoma. Chin Med J (Engl). 129:169–173. 2016. View Article : Google Scholar : PubMed/NCBI

13 

Barbu CG, Florin A, Neamţu MC, Avramescu ET, Terzea D, Miron A, Dănciulescu Miulescu R, Poiană C and Fica S: Papillary thyroid carcinoma with anaplastic dedifferentiation in the lymph node metastasis - a rare form of presentation even for a tall cell variant. Rom J Morphol Embryol. 56:527–531. 2015.PubMed/NCBI

14 

Wang Q, Zhu X and Tan Z: The clinical significance of the Delphian lymph node metastasis in papillary thyroid carcinoma. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 29:378–381. 2015.(In Chinese). PubMed/NCBI

15 

Liang XN, Guo RJ, Li S, Zheng ZM and Liang HD: Binary logistic regression analysis of solid thyroid nodules imaged by high-frequency ultrasonography, acoustic radiation force impulse, and contrast-enhanced ultrasonography. Eur Rev Med Pharmacol Sci. 18:3601–3610. 2014.PubMed/NCBI

16 

Ying M, Bhatia KS, Lee YP, Yuen HY and Ahuja AT: Review of ultrasonography of malignant neck nodes: Greyscale, Doppler, contrast enhancement and elastography. Cancer Imaging. 13:658–669. 2014. View Article : Google Scholar : PubMed/NCBI

17 

Isik S, Akbaba G, Berker D, Tutuncu YA, Ozuguz U, Aydin Y, Peksoy I and Guler S: Thyroid-related factors that influence preoperative localization of parathyroid adenomas. Endocr Pract. 18:26–33. 2012. View Article : Google Scholar : PubMed/NCBI

18 

Lee CW, Gong G and Roh JL: Intraoperative diagnosis of central compartment lymph node metastasis predicts recurrence of patients with papillary thyroid carcinoma and clinically node-negative lateral neck and may guide extent of initial surgery. World J Surg. 39:194–202. 2015. View Article : Google Scholar : PubMed/NCBI

19 

Li ZJ, An CM, Yan DG, Zhang XW, Zhang ZM, Xu ZG and Tang PZ: Significance of selective neck dissection in patients with cN0 thyroid carcinoma. Zhonghua Zhong Liu Za Zhi. 35:783–786. 2013.(In Chinese). PubMed/NCBI

20 

Chaojie Z, Shanshan L, Zhigong Z, Jie H, Shuwen X, Peizhi F, Jing X, Xiaowen G, Yang L and Wei Z: Evaluation of the clinical value of carbon nanoparticles as lymph node tracer in differentiated thyroid carcinoma requiring reoperation. Int J Clin Oncol. 17:32–34. 2015.

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Copy and paste a formatted citation
Spandidos Publications style
Liu B, Qin H, Zhang B, Shi T, Li C, Liu Y and Song M: Significance of clearing differentiated thyroid carcinoma lymph node by high‑frequency color Doppler ultrasonography. Oncol Lett 13: 253-257, 2017.
APA
Liu, B., Qin, H., Zhang, B., Shi, T., Li, C., Liu, Y., & Song, M. (2017). Significance of clearing differentiated thyroid carcinoma lymph node by high‑frequency color Doppler ultrasonography. Oncology Letters, 13, 253-257. https://doi.org/10.3892/ol.2016.5450
MLA
Liu, B., Qin, H., Zhang, B., Shi, T., Li, C., Liu, Y., Song, M."Significance of clearing differentiated thyroid carcinoma lymph node by high‑frequency color Doppler ultrasonography". Oncology Letters 13.1 (2017): 253-257.
Chicago
Liu, B., Qin, H., Zhang, B., Shi, T., Li, C., Liu, Y., Song, M."Significance of clearing differentiated thyroid carcinoma lymph node by high‑frequency color Doppler ultrasonography". Oncology Letters 13, no. 1 (2017): 253-257. https://doi.org/10.3892/ol.2016.5450
Copy and paste a formatted citation
x
Spandidos Publications style
Liu B, Qin H, Zhang B, Shi T, Li C, Liu Y and Song M: Significance of clearing differentiated thyroid carcinoma lymph node by high‑frequency color Doppler ultrasonography. Oncol Lett 13: 253-257, 2017.
APA
Liu, B., Qin, H., Zhang, B., Shi, T., Li, C., Liu, Y., & Song, M. (2017). Significance of clearing differentiated thyroid carcinoma lymph node by high‑frequency color Doppler ultrasonography. Oncology Letters, 13, 253-257. https://doi.org/10.3892/ol.2016.5450
MLA
Liu, B., Qin, H., Zhang, B., Shi, T., Li, C., Liu, Y., Song, M."Significance of clearing differentiated thyroid carcinoma lymph node by high‑frequency color Doppler ultrasonography". Oncology Letters 13.1 (2017): 253-257.
Chicago
Liu, B., Qin, H., Zhang, B., Shi, T., Li, C., Liu, Y., Song, M."Significance of clearing differentiated thyroid carcinoma lymph node by high‑frequency color Doppler ultrasonography". Oncology Letters 13, no. 1 (2017): 253-257. https://doi.org/10.3892/ol.2016.5450
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