Journal Articles

Open Access

Genetic alterations and epigenetic alterations of cancer‑associated fibroblasts (Review)

Heng Du, Guowei Che

Pages: 3-12 Published online on: 30 November 2016
Open Access

C‑type lectins facilitate tumor metastasis (Review)

Dongbing Ding, Yao Yao, Songbai Zhang, Chunjie Su, Yonglian Zhang

Pages: 13-21 Published online on: 24 November 2016
Open Access

Role of free testosterone levels in patients with metastatic castration-resistant prostate cancer receiving second-line therapy

Christoph A. von Klot, Markus A. Kuczyk, Alena Boeker, Christoph Reuter, Florian Imkamp, Thomas R.W. Herrmann, Hossein Tezval, Mario W. Kramer, Sven Perner, Axel S. Merseburger

Pages: 22-28 Published online on: 17 November 2016
Open Access

Efficacy of computed tomography features in predicting stage III thymic tumors

Yan Shen, Jianding Ye, Wentao Fang, Yu Zhang, Xiaodan Ye, Yonghong Ma, Libo Chen, Minghua Li

Pages: 29-36 Published online on: 23 November 2016

Role of gambogic acid and NaI131 in A549/DDP cells

Jing Huang, Xiaoli Zhu, Huan Wang, Shuhua Han, Lu Liu, Yan Xie, Daozhen Chen, Qiang Zhang, Li Zhang, Yue Hu

Pages: 37-44 Published online on: 25 November 2016
Open Access

Enhanced expression of hydroxylated ceramide in well‑differentiated endometrial adenocarcinoma

Toshiki Tajima, Masaki Miyazawa, Masaru Hayashi, Satoshi Asai, Masae Ikeda, Masako Shida, Takeshi Hirasawa, Masao Iwamori, Mikio Mikami

Pages: 45-50 Published online on: 22 November 2016
Open Access

CRKL overexpression promotes cell proliferation and inhibits apoptosis in endometrial carcinoma

Le Cai, He Wang, Qing Yang

Pages: 51-56 Published online on: 17 November 2016
Open Access

Effects of 17β-estradiol and tamoxifen on gastric cancer cell proliferation and apoptosis and ER-α36 expression

Xuming Wang, Qiuyue Chen, Xuan Huang, Feng Zou, Zhengqi Fu, Ying Chen, Yan Li, Zhaoyi Wang, Lijiang Liu

Pages: 57-62 Published online on: 23 November 2016
Open Access

Different but synergistic effects of bone marrow‑derived VEGFR2+ and VEGFR2‑CD45+ cells during hepatocellular carcinoma progression

Xiaolin Zhu, Hongyuan Zhou, Jingtao Luo, Yunlong Cui, Huikai Li, Wei Zhang, Feng Fang, Qiang Li, Ti Zhang

Pages: 63-68 Published online on: 22 November 2016
Open Access

Therapeutic response to a novel enzyme‑targeting radiosensitization treatment (KORTUC II) for residual lesions in patients with stage IV primary breast cancer, following induction chemotherapy with epirubicin and cyclophosphamide or taxane

Nobutaka Aoyama, Yasuhiro Ogawa, Miki Yasuoka, Hitomi Iwasa, Kana Miyatake, Rika Yoshimatsu, Tomoaki Yamanishi, Norihiko Hamada, Taiji Tamura, Kana Kobayashi, Yoriko Murata, Takuji Yamagami, Mitsuhiko Miyamura

Pages: 69-76 Published online on: 01 December 2016
Open Access

Correlation between liver cancer pain and the HIF-1 and VEGF expression levels

Geng Zhang, Gui-Yin Feng, Yan-Ru Guo, Dong-Qi Liang, Yuan Yuan, Hai-Lun Wang

Pages: 77-80 Published online on: 21 November 2016
Open Access

miR‑433 reduces cell viability and promotes cell apoptosis by regulating MACC1 in colorectal cancer

Jiaxin Li, Xuping Mao, Xing Wang, Ganggang Miao

Pages: 81-88 Published online on: 30 November 2016
Open Access

Effect of miR-23a on anoxia-induced phenotypic transformation of smooth muscle cells of rat pulmonary arteries and regulatory mechanism

Li Yan, Haixiang Gao, Chunzhi Li, Xiaowen Han, Xiaoyong Qi

Pages: 89-98 Published online on: 28 November 2016
Open Access

Effects of anti‑CD44 monoclonal antibody IM7 carried with chitosan polylactic acid-coated nano‑particles on the treatment of ovarian cancer

Yizhuo Yang, Xinghui Zhao, Xiuli Li, Zhifeng Yan, Zhongyu Liu, Yali Li

Pages: 99-104 Published online on: 22 November 2016
Open Access

Profiling of microRNAs in AML cells following overexpression or silencing of the VEGF gene

Li Li, Lixia Zhu, Yungui Wang, De Zhou, Jingjing Zhu, Wanzhuo Xie, Xiujin Ye

Pages: 105-110 Published online on: 22 November 2016
Open Access

Effects of the overexpression of IFITM5 and IFITM5 c.‑14C>T mutation on human osteosarcoma cells

Bao‑Yan Liu, Yan‑Qin Lu, Feng Han, Yong Wang, Xin‑Kai Mo, Jin‑Xiang Han

Pages: 111-118 Published online on: 23 November 2016
Open Access

Goniothalamin induces mitochondria-mediated apoptosis associated with endoplasmic reticulum stress-induced activation of JNK in HeLa cells

Thanet Sophonnithiprasert, Wilawan Mahabusarakam, Yukio Nakamura, Ramida Watanapokasin

Pages: 119-128 Published online on: 11 November 2016
Open Access

Combined detection of the expression of Nm23‑H1 and p53 is correlated with survival rates of patients with stage II and III colorectal cancer

Yinying Wu, Yi Li, Xiaoai Zhao, Danfeng Dong, Chunhui Tang, Enxiao Li, Qianqian Geng

Pages: 129-136 Published online on: 23 November 2016
Open Access

Clinical application of transanal ileal tube placement using X-ray monitoring

Dechun Li, Hongtao Du, Guoqing Shao, Yuanshun Xu, Ruihong Li, Qingzhong Tian

Pages: 137-140 Published online on: 29 November 2016
Open Access

Expression and clinical significance of PcG-associated protein RYBP in hepatocellular carcinoma

Xiaonian Zhu, Meng Yan, Wei Luo, Wei Liu, Yuan Ren, Chunhua Bei, Guifang Tang, Ruiling Chen, Shengkui Tan

Pages: 141-150 Published online on: 11 November 2016
Open Access

The effect of miR-146a on STAT1 expression and apoptosis in acute lymphoblastic leukemia Jurkat cells

Weihong Yan, Hua Guo, Feng Suo, Chunling Han, Hua Zheng, Tong Chen

Pages: 151-154 Published online on: 18 November 2016
Open Access

Evaluation of minimally invasive laser ablation in children with osteoid osteoma

Hao Wu, Cheng Lu, Ming Chen

Pages: 155-158 Published online on: 22 November 2016
Open Access

Bioinformatics analysis of key genes and latent pathway interactions based on the anaplastic thyroid carcinoma gene expression profile

Yun Huang, Yiming Tao, Xinying Li, Shi Chang, Bo Jiang, Feng Li, Zhi‑Ming Wang

Pages: 167-176 Published online on: 30 November 2016
Open Access

'Obligate' anaerobic Salmonella strain YB1 suppresses liver tumor growth and metastasis in nude mice

Chang‑Xian Li, Bin Yu, Lei Shi, Wei Geng, Qiu‑Bin Lin, Chang‑Chun Ling, Mei Yang, Kevin T. P. Ng, Jian‑Dong Huang, Kwan Man

Pages: 177-183 Published online on: 30 November 2016
Open Access

Bilateral ovarian carcinomas differ in the expression of metastasis-related genes

Marianne Lislerud Smebye, Lisbeth Haugom, Ben Davidson, Claes Göran Trope, Sverre Heim, Rolf Inge Skotheim, Francesca Micci

Pages: 184-190 Published online on: 14 November 2016
Open Access

Sometimes it is better to wait: First Italian case of a newborn with transient abnormal myelopoiesis and a favorable prognosis

Guglielmo Salvatori, Silvia Foligno, Pietro Sirleto, Silvia Genovese, Serena Russo, Valentina Coletti, Andrea Dotta, Matteo Luciani

Pages: 191-195 Published online on: 21 November 2016
Open Access

Influence of VEGFR single nucleotide polymorphisms on the efficacy of sunitinib therapy against renal cell carcinoma

Rui Liu, Xiaojie Wang, Wei Li, Tao Shou, Likun Zhou, Yunfen Li, Ming Bai, Qiang Pei

Pages: 201-205 Published online on: 18 November 2016
Open Access

Increased chemosensitivity and radiosensitivity of human breast cancer cell lines treated with novel functionalized single‑walled carbon nanotubes

Yijun Jia, Ziyi Weng, Chuanying Wang, Mingjie Zhu, Yunshu Lu, Longlong Ding, Yongkun Wang, Xianhua Cheng, Qing Lin, Kejin Wu

Pages: 206-214 Published online on: 21 November 2016
Open Access

Molecular heterogeneity in the novel fusion gene APIP-FGFR2: Diversity of genomic breakpoints in gastric cancer with high-level amplifications at 11p13 and 10q26

Takashi Okuda, Tomohiko Taki, Kazuhiro Nishida, Yoshiaki Chinen, Hisao Nagoshi, Chouhei Sakakura, Masafumi Taniwaki

Pages: 215-221 Published online on: 15 November 2016
Open Access

Increased expression of S100A6 promotes cell proliferation in gastric cancer cells

Xiao‑Hong Wang, Hong Du, Lin Li, Duan‑Fang Shao, Xi‑Yao Zhong, Ying Hu, Yi‑Qiang Liu, Xiao‑Fang Xing, Xiao‑Jing Cheng, Ting Guo, Shen Li, Zi‑Yu Li, Zhao‑De Bu, Xian‑Zi Wen, Lian‑Hai Zhang, Jia‑Fu Ji

Pages: 222-230 Published online on: 22 November 2016
Open Access

Comparison of the breast and areola approaches for endoscopic thyroidectomy in patients with microcarcinoma

Gaolei Jia, Zhilong Tian, Hailin Xi, Su Feng, Xiaokai Wang, Xinbao Gao

Pages: 231-235 Published online on: 28 November 2016
Open Access

CEP55 overexpression predicts poor prognosis in patients with locally advanced esophageal squamous cell carcinoma

Wenpeng Jiang, Zhou Wang, Yang Jia

Pages: 236-242 Published online on: 22 November 2016
Open Access

DHA blocks TPA-induced cell invasion by inhibiting MMP-9 expression via suppression of the PPAR‑γ/NF-κB pathway in MCF-7 cells

Jin‑Ki Hwang, Hong‑Nu Yu, Eun‑Mi Noh, Jeong‑Mi Kim, On‑Yu Hong, Hyun Jo Youn, Sung Hoo Jung, Kang‑Beom Kwon, Jong‑Suk Kim, Young‑Rae Lee

Pages: 243-249 Published online on: 11 November 2016
Open Access

Factors related to endocrine changes and hormone substitution treatment during pre- and post-operation stages in craniopharyngioma

Fenglei Sun, Xintang Sun, Xiaolong Du, Hongshun Xing, Bin Yang

Pages: 250-252 Published online on: 22 November 2016
Open Access

Significance of clearing differentiated thyroid carcinoma lymph node by high‑frequency color Doppler ultrasonography

Bing Liu, Huadong Qin, Bin Zhang, Tiefeng Shi, Chuanle Li, Yao Liu, Meiyue Song

Pages: 253-257 Published online on: 30 November 2016

Cell death in a co‑culture of hepatocellular carcinoma cells and human umbilical vascular endothelial cells in a medium lacking glucose and arginine

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige

Pages: 258-262 Published online on: 30 November 2016
Open Access

The diagnostic utility of PAX8 immunostaining of malignant peritoneal mesothelioma presenting as serous ovarian carcinoma: A single‑center report of two cases

Kohei Nakamura, Kentaro Nakayama, Risa Nagaoka, Kiyoka Nishisako, Masako Ishikawa, Hiroshi Katagiri, Tomoka Ishibashi, Emi Sato, Chika Amano, Satoru Kyo

Pages: 263-266 Published online on: 30 November 2016

Multiple pulmonary emboli as a result of renal cell carcinoma: A case report

Bing Li, Hong Zeng, Mei Ding, Ping Yang, Yuquan He

Pages: 267-270 Published online on: 21 November 2016

Recognition of tumor antigens in 4T1 cells by natural IgM from three strains of mice with different susceptibilities to spontaneous breast cancer

Mariana Díaz‑Zaragoza, Ricardo Hernández‑Ávila, Pedro Ostoa‑Saloma

Pages: 271-274 Published online on: 23 November 2016
Open Access

Circulating tumor cells expressing cancer stem cell marker CD44 as a diagnostic biomarker in patients with gastric cancer

Toru Watanabe, Tomoyuki Okumura, Katsuhisa Hirano, Tetsuji Yamaguchi, Shinichi Sekine, Takuya Nagata, Kazuhiro Tsukada

Pages: 281-288 Published online on: 24 November 2016

Comparative proteomic analysis of paclitaxel resistance‑related proteins in human breast cancer cell lines

Hiroya Fujioka, Akiko Sakai, Satoru Tanaka, Kosei Kimura, Akiko Miyamoto, Mitsuhiko Iwamoto, Kazuhisa Uchiyama

Pages: 289-295 Published online on: 30 November 2016

Neuroprotective effect of matrine on MPTP-induced Parkinson's disease and on Nrf2 expression

Fanhua Meng, Jianhui Wang, Fuxiang Ding, Yunliang Xie, Yingjie Zhang, Jie Zhu

Pages: 296-300 Published online on: 14 November 2016

Cervical intraepithelial neoplasia in pregnancy: Interference of pregnancy status with p16 and Ki-67 protein expression

Andrea Ciavattini, Francesco Sopracordevole, Jacopo Di Giuseppe, Lorenzo Moriconi, Guendalina Lucarini, Francesca Mancioli, Antonio Zizzi, Gaia Goteri

Pages: 301-306 Published online on: 29 November 2016

Adefovir dipivoxil-induced Fanconi syndrome and its predictive factors: A study of 28 cases

Yong Lin, Fan Pan, Yingchao Wang, Ziqian Chen, Chun Lin, Lvfeng Yao, Xin Zhang, Rui Zhou, Chen Pan

Pages: 307-314 Published online on: 17 November 2016

A methodological procedure for evaluating the impact of hemolysis on circulating microRNAs

Sara Pizzamiglio, Susanna Zanutto, Chiara M. Ciniselli, Antonino Belfiore, Stefano Bottelli, Manuela Gariboldi, Paolo Verderio

Pages: 315-320 Published online on: 30 November 2016
Open Access

ALDH1 and podoplanin expression patterns predict the risk of malignant transformation in oral leukoplakia

Umma Habiba, Kyoko Hida, Tetsuya Kitamura, Aya Yanagawa Matsuda, Fumihiro Higashino, Yoichi M. Ito, Yoichi Ohiro, Yasunori Totsuka, Masanobu Shindoh

Pages: 321-328 Published online on: 10 November 2016
Open Access

MicroRNA‑101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A

Lumin Wang, Jiayi Yao, Hongfei Sun, Kang He, Dongdong Tong, Tusheng Song, Chen Huang

Pages: 329-338 Published online on: 23 November 2016

Tumor necrosis factor receptor 2 promotes growth of colorectal cancer via the PI3K/AKT signaling pathway

Tao Zhao, Huihui Li, Zifeng Liu

Pages: 342-346 Published online on: 21 November 2016

Inhibitory effect of dexamethasone on residual Lewis lung cancer cells in mice following palliative surgery

Ningbo Sun, Huaijun Ji, Wei Wang, Qiang Zhu, Ming Cao, Qi Zang

Pages: 356-362 Published online on: 23 November 2016

H19 promotes endometrial cancer progression by modulating epithelial-mesenchymal transition

Le Zhao, Zhen Li, Wei Chen, Wen Zhai, Jingjing Pan, Huan Pang, Xu Li

Pages: 363-369 Published online on: 16 November 2016

Anticancer activity of sesquiterpenoids extracted from Solanum lyratum via the induction of mitochondria-mediated apoptosis

Min Chen, Jian Wu, Xing‑Xing Zhang, Qiong Wang, Shi‑Hai Yan, Hai‑Dan Wang, Sheng‑Lin Liu, Xi Zou

Pages: 370-376 Published online on: 21 November 2016

Role of Annexin A2 in the EGF-induced epithelial-mesenchymal transition in human CaSki cells

Lei Cui, Jian Song, Liting Wu, Luhui Cheng, Aijun Chen, Yanlin Wang, Yingdi Huang, Liming Huang

Pages: 377-383 Published online on: 21 November 2016

Gambogic acid inhibits the growth of ovarian cancer tumors by regulating p65 activity

Qiusha Tang, Mudan Lu, Huan Zhou, Daozhen Chen, Lu Liu

Pages: 384-388 Published online on: 24 November 2016

Solid lipid nanoparticles with TPGS and Brij 78: A co-delivery vehicle of curcumin and piperine for reversing P-glycoprotein-mediated multidrug resistance in vitro

Jingling Tang, Hongyu Ji, Jinmei Ren, Mengting Li, Nannan Zheng, Linhua Wu

Pages: 389-395 Published online on: 23 November 2016

Transcription factor Oct4 promotes osteosarcoma by regulating lncRNA AK055347

Hongwu Fan, Guangyao Liu, Changfu Zhao, Xuefeng Li, Xiaoyu Yang

Pages: 396-402 Published online on: 21 November 2016

HDAC2 regulates cell proliferation, cell cycle progression and cell apoptosis in esophageal squamous cell carcinoma EC9706 cells

Shenglei Li, Feng Wang, Yunhui Qu, Xiaoqi Chen, Ming Gao, Jianping Yang, Dandan Zhang, Na Zhang, Wencai Li, Hongtao Liu

Pages: 403-409 Published online on: 25 November 2016

Anti-tumor and anti-invasion effects of a combination of 4-methylumbelliferone and ionizing radiation in human fibrosarcoma cells

Ryo Saga, Satoru Monzen, Mitsuru Chiba, Hironori Yoshino, Toshiya Nakamura, Yoichiro Hosokawa

Pages: 410-416 Published online on: 15 November 2016

miR-506 suppresses neuroblastoma metastasis by targeting ROCK1

Dianguo Li, Yanhua Cao, Jinliang Li, Jialong Xu, Qian Liu, Xiaogang Sun

Pages: 417-422 Published online on: 29 November 2016

Per2 participates in AKT-mediated drug resistance in A549/DDP lung adenocarcinoma cells

Bo Chen, Yaoxi Tan, Yan Liang, Yan Li, Lei Chen, Shuangshuang Wu, Wei Xu, Yan Wang, Weihong Zhao, Jianqing Wu

Pages: 423-428 Published online on: 24 November 2016

Percutaneous microwave ablation for benign focal liver lesions: Initial clinical results

Zhigang Cheng, Ping Liang, Xiaoling Yu, Zhiyu Han, Fangyi Liu, Jie Yu, Xin Li

Pages: 429-434 Published online on: 22 November 2016

miR-143 inhibits bladder cancer cell proliferation and enhances their sensitivity to gemcitabine by repressing IGF-1R signaling

Hengbing Wang, Qi Li, Xiaobing Niu, Gongcheng Wang, Sinian Zheng, Guangbo Fu, Zengjun Wang

Pages: 435-440 Published online on: 16 November 2016

Effects of physical activity on systemic oxidative/DNA status in breast cancer survivors

Barbara Tomasello, Giuseppe Antonio Malfa, Angela Strazzanti, Santi Gangi, Claudia Di Giacomo, Francesco Basile, Marcella Renis

Pages: 441-448 Published online on: 30 November 2016

Protective effects of sodium selenite supplementation against irradiation-induced damage in non-cancerous human esophageal cells

Irma M. Puspitasari, Chiho Yamazaki, Rizky Abdulah, Mirasari Putri, Satomi Kameo, Takashi Nakano, Hiroshi Koyama

Pages: 449-454 Published online on: 24 November 2016

ETS‑related gene is a novel prognostic factor in childhood acute lymphoblastic leukemia

Hai‑Zhao Zhao, Ming Jia, Ze‑Bin Luo, Xiao‑Jun Xu, Si‑Si Li, Jing‑Ying Zhang, Xiao‑Ping Guo, Yong‑Min Tang

Pages: 455-462 Published online on: 18 November 2016

Association of leptin, visfatin, apelin, resistin and adiponectin with clear cell renal cell carcinoma

Hai‑Ping Zhang, Jian Zou, Zhuo‑Qun Xu, Jun Ruan, Shu‑Dong Yang, Ying Yin, Hui‑Jun Mu

Pages: 463-468 Published online on: 22 November 2016

Cigarette smoke extract-induced proliferation of normal human urothelial cells via the MAPK/AP‑1 pathway

Hao Geng, Li Zhao, Zhaofeng Liang, Zhiqiang Zhang, Dongdong Xie, Liangkuan Bi, Yi Wang, Tao Zhang, Lei Cheng, Dexin Yu, Caiyun Zhong

Pages: 469-475 Published online on: 22 November 2016

Host knockout of E-prostanoid 2 receptors reduces tumor growth and causes major alterations of gene expression in prostaglandin E2-producing tumors

Annika Gustafsson Asting, Britt‑Marie Iresjö, Camilla Nilsberth, Ulrika Smedh, Kent Lundholm

Pages: 476-482 Published online on: 30 November 2016

Downregulation of caveolin-1 increases the sensitivity of drug-resistant colorectal cancer HCT116 cells to 5-fluorouracil

Zhaoyang Li, Ning Wang, Changxin Huang, Yanhong Bao, Yiqian Jiang, Guiting Zhu

Pages: 483-487 Published online on: 16 November 2016

Analysis of molecular markers as predictive factors of lymph node involvement in breast carcinoma

Luciana Marques Paula, Luis Henrique Ferreira de Moraes, Abaeté Leite do Canto, Laurita dos Santos, Airton Abrahão Martin, Silvia Regina Rogatto, Renata de Azevedo Canevari

Pages: 488-496 Published online on: 28 November 2016

Y-box-binding protein 1 contributes to IL-7-mediated survival signaling in B-cell precursor acute lymphoblastic leukemia

Amina Kariminia, Sabine M. Ivison, Vivian M. Leung, Susanna Sung, Nicole Couto, Jacob Rozmus, Nina Rolf, Aru Narendran, Sandra E. Dunn, Gregor S.D. Reid, Kirk R. Schultz

Pages: 497-505 Published online on: 28 November 2016

Prognostic significance of Notch ligands in patients with non‑small cell lung cancer

Joanna Pancewicz‑Wojtkiewicz, Andrzej Eljaszewicz, Oksana Kowalczuk, Wieslawa Niklinska, Radoslaw Charkiewicz, Miroslaw Kozłowski, Agnieszka Miasko, Marcin Moniuszko

Pages: 506-510 Published online on: 23 November 2016

Bovine lactoferricin P13 triggers ROS‑mediated caspase‑dependent apoptosis in SMMC7721 cells

Lixiang Meng, Geliang Xu, Jiansheng Li, Wenbin Liu, Weidong Jia, Jinliang Ma, Decheng Wei

Pages: 511-517 Published online on: 22 November 2016

Isoimperatorin induces apoptosis of the SGC-7901 human gastric cancer cell line via the mitochondria-mediated pathway

Kehui Tong, Chang Xin, Wenzhong Chen

Pages: 518-524 Published online on: 15 November 2016
Journal Cover

January-2017
Volume 13 Issue 1

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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