|
1
|
Senthi S, Haasbeek CJ, Slotman BJ and
Senan S: Outcomes of stereotactic ablative radiotherapy for central
lung tumours: A systematic review. Radiother Oncol. 106:276–282.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Shen Z, Wu X, Wang Z, Li B and Zhu X:
Effect of miR-18a overexpression on the radiosensitivity of
non-small cell lung cancer. Int J Clin Exp Pathol. 8:643–648.
2015.PubMed/NCBI
|
|
3
|
Subtil FS, Wilhelm J, Bill V, Westholt N,
Rudolph S, Fischer J, Scheel S, Seay U, Fournier C, Taucher-Scholz
G, et al: Carbon ion radiotherapy of human lung cancer attenuates
HIF-1 signaling and acts with considerably enhanced therape-utic
efficiency. FASEB J. 28:1412–1421. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Cannon DM, Mehta MP, Adkison JB, Khuntia
D, Traynor AM, Tomé WA, Chappell RJ, Tolakanahalli R, Mohindra P,
Bentzen SM and Cannon GM: Dose-limiting toxicity after
hypofractionated dose-escalated radiotherapy in non-small-cell lung
cancer. J Clin Oncol. 31:4343–4348. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kim E, Youn H, Kwon T, Son B, Kang J, Yang
HJ, Seong KM, Kim W and Youn B: PAK1 tyrosine phosphorylation is
required to induce epithelial-mesenchymal transition and
radioresistance in lung cancer cells. Cancer Res. 74:5520–5531.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Sekhar KR, Benamar M, Venkateswaran A,
Sasi S, Penthala NR, Crooks PA, Crooks PA, Hann SR, Geng L, Balusu
R, et al: Targeting nucleophosmin 1 represents a rational strategy
for radiationsensitization. Int J Radiat Oncol Biol Phys.
89:1106–1114. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Theys J, Yahyanejad S, Habets R, Span P,
Dubois L, Paesmans K, Kattenbeld B, Cleutjens J, Groot AJ,
Schuurbiers OC, et al: High NOTCH activity induces radiation
resistance in non small cell lung cancer. Radiother Oncol.
108:440–445. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Okaichi K, Nose K, Kotake T, Izumi N and
Kudo T: Phosphorylation of p53 modifies sensitivity to ionizing
radiation. Anticancer Res. 31:2255–2258. 2011.PubMed/NCBI
|
|
9
|
Jamal M, Rath BH, Williams ES, Camphausen
K and Tofilon PJ: Microenvironmental regulation of glioblastoma
radioresponse. Clin Cancer Res. 16:6049–6059. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Ayouaz A, Raynaud C, Heride C, Revaud D
and Sabatier L: Telomeres: Hallmarks of radiosensitivity.
Biochimie. 90:60–72. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Quintana-Cabrera R and Bolaños JP:
Glutathione and γ-glutamylcysteine in the antioxidant and survival
functions of mitochondria. Biochem Soc Trans. 41:106–110. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Pereira CV, Nadanaciva S, Oliveira PJ and
Will Y: The contribution of oxidative stress to drug-induced organ
toxicity and its detection in vitro and in vivo. Expert Opin Drug
Metab Toxicol. 8:219–237. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Slemmer JE, Shacka JJ, Sweeney MI and
Weber JT: Antioxidants and free radical scavengers for the
treatment of stroke, traumatic brain injury and aging. Curr Med
Chem. 15:404–414. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Wells PG, Bhuller Y, Chen CS, Jeng W,
Kasapinovic S, Kennedy JC, Kim PM, Laposa RR, McCallum GP, Nicol
CJ, et al: Molecular and biochemical mechanisms in teratogenesis
involving reactive oxygen species. Toxicol Appl Pharmacol 207 (2
Suppl). 354–366. 2005. View Article : Google Scholar
|
|
15
|
Ogunrinu TA and Sontheimer H: Hypoxia
increases the dependence of glioma cells on glutathione. J Biol
Chem. 285:37716–37724. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Honda T, Coppola S, Ghibelli L, Cho SH,
Kagawa S, Spurgers KB, Brisbay SM, Roth JA, Meyn RE, Fang B and
McDonnell TJ: GSH depletion enhances adenoviral bax-induced
apoptosis in lung cancer cells. Cancer Gene Ther. 11:249–255. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lee JH, Tak JK, Park KM and Park JW:
N-t-Butyl hydroxylamine regulates ionizing radiation-induced
apoptosis in U937 cells. Biochimie. 89:1509–1516. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Karthikeyan S, Kanimozhi G, Prasad NR and
Mahalakshmi R: Radiosensitizing effect of ferulic acid on human
cervical carcinoma cells in vitro. Toxicol In Vitro. 25:1366–1375.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Keshmiri-Neghab H, Goliaei B and Nikoofar
A: Gossypol enhances radiation induced autophagy in glioblastoma
multiforme. Gen Physiol Biophys. 33:433–442. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Elbaz HA, Lee I, Antwih DA, Liu J,
Hüttemann M and Zielske SP: Epicatechin stimulates mitochondrial
activity and selectively sensitizes cancer cells to radiation. PLoS
One. 9:e883222014. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zang LL, Wu BN, Lin Y, Wang J, Fu L and
Tang ZY: Research progress of ursolic acid's anti-tumor actions.
Chin J Integr Med. 20:72–79. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wang W, Zhao C, Jou D, Lü J, Zhang C, Lin
L and Lin J: Ursolic acid inhibits the growth of colon
cancer-initiating cells by targeting STAT3. Anticancer Res.
33:4279–4284. 2013.PubMed/NCBI
|
|
23
|
Huang CY, Lin CY, Tsai CW and Yin MC:
Inhibition of cell proliferation, invasion and migration by ursolic
acid in human lung cancer cell lines. Toxicol In Vitro.
25:1274–1280. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Park JH, Kwon HY, Sohn EJ, Kim KA, Kim B,
Jeong SJ, Song JH, Koo JS and Kim SH: Inhibition of Wnt/β-catenin
signaling mediates ursolic acid-induced apoptosis in PC-3 prostate
cancer cells. Pharmacol Rep. 65:1366–1374. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Xavier CP, Lima CF, Pedro DF, Wilson JM,
Kristiansen K and Pereira-Wilson C: Ursolic acid induces cell death
and modulates autophagy through JNK pathway in apoptosis-resistant
colorectal cancer cells. J Nutr Biochem. 24:706–712. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Li J, Liang X and Yang X: Ursolic acid
inhibits growth and induces apoptosis in gemcitabine-resistant
human pancreatic cancer via the JNK and PI3K/Akt/NF-κB pathways.
Oncol Rep. 28:501–510. 2012.PubMed/NCBI
|
|
27
|
Li Y, Xing D, Chen Q and Chen WR:
Enhancement of chemotherapeutic agent-induced apoptosis by
inhibition of NF-kappaB using ursolic acid. Int J Cancer.
127:462–473. 2010.PubMed/NCBI
|
|
28
|
Koh SJ, Tak JK, Kim ST, Nam WS, Kim SY,
Park KM and Park JW: Sensitization of ionizing radiation-induced
apoptosis by ursolic acid. Free Radic Res. 46:339–345. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Huq F, Yu JQ, Beale P, Chan C, Arzuman L,
Nessa MU and Mazumder ME: Combinations of platinums and selected
phytochemicals as a means of overcoming resistance in ovarian
cancer. Anticancer Res. 34:541–545. 2014.PubMed/NCBI
|
|
30
|
Romm H, Barnard S, Boulay-Greene H, De
Amicis A, De Sanctis S, Franco M, Herodin F, Jones A, Kulka U,
Lista F, et al: Laboratory intercomparison of the cytokinesis-block
micronucleus assay. Radiat Res. 180:120–128. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Qi R and Jin W, Wang J, Yi Q, Yu M, Xu S
and Jin W: Oleanolic acid enhances the radiosensitivity of tumor
cells under mimetic hypoxia through the reduction in intracellular
GSH content and HIF-1α expression. Oncol Rep. 31:2399–2406.
2014.PubMed/NCBI
|
|
32
|
Wang J, Yu M, Xiao L, Xu S, Yi Q and Jin
W: Radiosensitizing effect of oleanolic acid on tumor cells through
the inhibition of GSH synthesis in vitro. Oncol Rep. 30:917–924.
2013.PubMed/NCBI
|
|
33
|
Shan JZ, Xuan YY, Ruan SQ and Sun M:
Proliferation-inhibiting and apoptosis-inducing effects of ursolic
acid and oleanolic acid on multi-drug resistance cancer cells in
vitro. Chin J Integr Med. 17:607–611. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Berghoff AS, Ilhan-Mutlu A, Wöhrer A,
Hackl M, Widhalm G, Hainfellner JA, Dieckmann K, Melchardt T, Dome
B, Heinzl H, et al: Prognostic significance of Ki67 proliferation
index, HIF1 alpha index and microvascular density in patients with
non-small cell lung cancer brain metastases. Strahlenther Onkol.
190:676–685. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Yoshimura M, Itasaka S, Harada H and
Hiraoka M: Microenvironment and radiation therapy. Biomed Res Int.
2013:6853082013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
van Baardwijk A, Dooms C, van Suylen RJ,
Verbeken E, Hochstenbag M, Dehing-Oberije C, Rupa D, Pastorekova S,
Stroobants S, Buell U, et al: The maximum uptake of
(18)F-deoxyglucose on positron emission tomography scan correlates
with survival, hypoxia inducible factor-1alpha and GLUT-1 in
non-small cell lung cancer. Eur J Cancer. 43:1392–1398. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Zeng L, Ou G, Itasaka S, Harada H, Xie X,
Shibuya K, Kizaka-Kondoh S, Morinibu A, Shinomiya K and Hiraoka M:
TS-1 enhances the effect of radiotherapy by suppressing
radiation-induced hypoxia-inducible factor-1 activation and
inducing endothelial cell apoptosis. Cancer Sci. 99:2327–2335.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Rolfo A, Many A, Racano A, Tal R,
Tagliaferro A, Ietta F, Wang J, Post M and Caniggia I:
Abnormalities in oxygen sensing define early and late onset
preeclampsia as distinct pathologies. PLoS One. 5:e132882010.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Semenza GL: HIF-1 mediates metabolic
responses to intratumoral hypoxia and oncogenic mutations. J Clin
Invest. 123:3664–3671. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
40
|
Jin WS, Kong ZL, Shen ZF, Jin YZ, Zhang WK
and Chen GF: Regulation of hypoxia inducible factor-1α expression
by the alteration of redox status in HepG2 cells. J Exp Clin Cancer
Res. 30:612011. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Wei L, Lu J, Feng L, Li S, Shan J and Li
Y: Construction of recombinant adenovirus vector containing a
modified gene that codes for human hypoxia-inducible factor-1alpha
without oxygen-dependent degradation. Plasmid. 63:20–26. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Kassi E, Sourlingas TG, Spiliotaki M,
Papoutsi Z, Pratsinis H, Aligiannis N and Moutsatsou P: Ursolic
acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast
cancer cells. Cancer Invest. 27:723–733. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Biddlestone-Thorpe L, Sajjad M, Rosenberg
E, Beckta JM, Valerie NC, Tokarz M, Adams BR, Wagner AF, Khalil A,
Gilfor D, et al: ATM kinase inhibition preferentially sensitizes
p53-mutant glioma to ionizing radiation. Clin Cancer Res.
19:3189–3200. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Kim JC, Ali MA, Nandi A, Mukhopadhyay P,
Choy H, Cao C and Saha D: Correlation of HER1/EGFR expression and
degree of radiosensitizing effect of the HER1/EGFR-tyrosine kinase
inhibitor erlotinib. Indian J Biochem Biophys. 42:358–365.
2005.PubMed/NCBI
|
|
45
|
Kashino G, Prise KM, Suzuki K, Matsuda N,
Kodama S, Suzuki M, Nagata K, Kinashi Y, Masunaga S, Ono K and
Watanabe M: Effective suppression of bystander effects by DMSO
treatment of irradiated CHO cells. J Radiat Res. 48:327–333. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Thierens H and Vral A: The micronucleus
assay in radiation accidents. Ann Ist Super Sanita. 45:260–264.
2009.PubMed/NCBI
|
|
47
|
Romm H, Barnard S, Boulay-Greene H, De
Amicis A, De Sanctis S, Franco M, Herodin F, Jones A, Kulka U,
Lista F, et al: Laboratory intercomparison of the cytokinesis-block
micronucleus assay. Radiat Res. 180:120–128. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Singh A, Bodas M, Wakabayashi N, Bunz F
and Biswal S: Gain of Nrf2 function in non-small-cell lung cancer
cells confers radioresistance. Antioxid Redox Signal. 13:1627–1637.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Das B, Yeger H, Tsuchida R, Torkin R, Gee
MF, Thorner PS, Shibuya M, Malkin D and Baruchel S: A
hypoxia-driven vascular endothelial growth factor/Flt1 autocrine
loop interacts with hypoxia-inducible factor-1alpha through
mitogen-activated protein kinase/extracellular signal-regulated
kinase 1/2 pathway in neuroblastoma. Cancer Res. 65:7267–7275.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Lin CC, Huang CY, Mong MC, Chan CY and Yin
MC: Antiangiogenic potential of three triterpenic acids in human
liver cancer cells. J Agric Food Chem. 59:755–762. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Guo S, Miyake M, Liu KJ and Shi H:
Specific inhibition of hypoxia inducible factor 1 exaggerates cell
injury induced by in vitro ischemia through deteriorating cellular
redox environment. J Neurochem. 108:1309–1321. 2009. View Article : Google Scholar : PubMed/NCBI
|
