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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2017 Volume 13 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

IκB‑α: At the crossroad between oncogenic and tumor‑suppressive signals (Review)

Alessandro Morotti, Sabrina Crivellaro, Cristina Panuzzo, Giovanna Carrà, Angelo Guerrasio, Giuseppe Saglio
Pages: 531-534
Published online on: 06 December 2016

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Review

Familial risk for lung cancer (Review)

Madiha Kanwal, Xiao‑Ji Ding, Yi Cao
Pages: 535-542
Published online on: 20 December 2016

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Review Open Access

From inflammation to gastric cancer: Role of Helicobacter pylori (Review)

Xiao-Ying Zhang, Pei-Ying Zhang, Mourad A.M. Aboul-Soud
Pages: 543-548
Published online on: 15 December 2016

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Review

A novel hysteroscopic approach for ovarian cancer screening/early diagnosis (Review)

Salvatore Gizzo, Marco Noventa, Michela Quaranta, Amerigo Vitagliano, Carlo Saccardi, Pietro Litta, Donato Antona
Pages: 549-553
Published online on: 14 December 2016

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Article Open Access

Anti‑tumor effects of metformin on head and neck carcinoma cell lines: A systematic review

Daniela Fortunato Rêgo, Silvia Taveira Elias, Angélica Amorim Amato, Graziela De Luca Canto, Eliete Neves Silva Guerra
Pages: 554-566
Published online on: 20 December 2016

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Article Open Access

Effect of targeted silencing of IL-8 on in vitro migration and invasion of SKOV3 ovarian cancer cells

Yanyu Li, Ling Liu, Zeyuan Yin, Hui Xu, Shuang Li, Wei Tao, Hui Cheng, Lei Du, Xueyuan Zhou, Bei Zhang
Pages: 567-572
Published online on: 16 December 2016

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Article Open Access

MicroRNA‑320a downregulation mediates human liver cancer cell proliferation through the Wnt/β‑catenin signaling pathway Retraction in /10.3892/ol.2025.15284

Caicheng Lu, Zengwei Liao, Minxian Cai, Guirong Zhang
Pages: 573-578
Published online on: 12 December 2016

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Article Open Access

Human serum albumin-mediated apoptin delivery suppresses breast cancer cell growth in vitro and in vivo

Fang Wu, Yizhi Liu, Jian Li, Lei Hou, Fuxi Lei, Shangke Huang, Lu Feng, Xinhan Zhao
Pages: 579-586
Published online on: 07 December 2016

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Article Open Access

DKK4 enhances resistance to chemotherapeutics 5‑Fu and YN968D1 in colorectal cancer cells

Shengli He, Jie Shen, Nanhua Hu, Xuanfu Xu, Jin Li
Pages: 587-592
Published online on: 06 December 2016

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Article Open Access

A malignant inflammatory myofibroblastic tumor of the hypopharynx harboring the 3a/b variants of the EML4‑ALK fusion gene

Lucia Anna Muscarella, Giulio Rossi, Domenico Trombetta, Annamaria La Torre, Leonarda Di Candia, Maria Cecilia Mengoli, Angelo Sparaneo, Vito Michele Fazio, Paolo Graziano
Pages: 593-598
Published online on: 14 December 2016

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Article Open Access

Melittin inhibits the invasion of MCF‑7 cells by downregulating CD147 and MMP‑9 expression

Jianjun Wang, Fengyu Li, Jiang Tan, Xuewei Peng, Lili Sun, Ping Wang, Shengnan Jia, Qingmiao Yu, Hongliang Huo, Hongyan Zhao
Pages: 599-604
Published online on: 20 December 2016

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Article Open Access

Danshensu, a major water‑soluble component of Salvia miltiorrhiza, enhances the radioresponse for Lewis Lung Carcinoma xenografts in mice

Hong‑Ying Cao, Rui‑Lin Ding, Meng Li, Mao‑Nan Yang, Ling‑Lin Yang, Jing‑Bo Wu, Bo Yang, Jing Wang, Cui‑Lian Luo, Qing‑Lian Wen
Pages: 605-612
Published online on: 16 December 2016

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Article Open Access

Resveratrol promotes regression of renal carcinoma cells via a renin‑angiotensin system suppression‑dependent mechanism

Jianchang Li, Mingning Qiu, Lieqian Chen, Lei Liu, Guobin Tan, Jianjun Liu
Pages: 613-620
Published online on: 20 December 2016

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Article Open Access

Expression of Axl and its prognostic significance in human breast cancer

Gaoyuan Jin, Zhenzhen Wang, Jianguang Wang, Like Zhang, Yanbin Chen, Pengfei Yuan, Dechun Liu
Pages: 621-628
Published online on: 20 December 2016

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Article Open Access

Identification of genes associated with tongue cancer in patients with a history of tobacco and/or alcohol use

Yin Zhao, Dongna Fu, Chengbi Xu, Jingpu Yang, Zonggui Wang
Pages: 629-638
Published online on: 14 December 2016

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Article Open Access

Imbalanced adaptive responses associated with microsatellite instability in cholangiocarcinoma

Watcharin Loilome, Sasithorn Kadsanit, Kanha Muisook, Puangrat Yongvanit, Nisana Namwat, Anchalee Techasen, Anucha Puapairoj, Narong Khuntikeo, Pichai Phonjit
Pages: 639-646
Published online on: 08 December 2016

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Article Open Access

Aspirin enhances the cytotoxic activity of bortezomib against myeloma cells via suppression of Bcl-2, survivin and phosphorylation of AKT

Jiang‑Hua Ding, Li‑Ya Yuan, Guo‑An Chen
Pages: 647-654
Published online on: 08 December 2016

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Article Open Access

Anti-metastatic activity of fangchinoline in human gastric cancer AGS cells

Zhengrong Chen, Tengfei He, Kui Zhao, Chungen Xing
Pages: 655-660
Published online on: 02 December 2016

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Article Open Access

LASS2 inhibits growth and invasion of bladder cancer by regulating ATPase activity Corrigendum in /10.3892/ol.2022.13188

Haifeng Wang, Yigang Zuo, Mingxia Ding, Changxing Ke, Ruping Yan, Hui Zhan, Jingyu Liu, Wei Wang, Ning Li, Jiansong Wang
Pages: 661-668
Published online on: 20 December 2016

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Article Open Access

Plasma miR‑145, miR‑20a, miR‑21 and miR‑223 as novel biomarkers for screening early‑stage non‑small cell lung cancer

Hui Zhang, Feng Mao, Tuyang Shen, Qingquan Luo, Zhengping Ding, Liqiang Qian, Jia Huang
Pages: 669-676
Published online on: 06 December 2016

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Article Open Access

Evaluation of nano‑magnetic fluid on malignant glioma cells

Hongsheng Xu, Hailiang Zong, Chong Ma, Xing Ming, Ming Shang, Kai Li, Xiaoguang He, Lei Cao
Pages: 677-680
Published online on: 19 December 2016

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Article Open Access

Ginsenoside Rh2 enhances the antitumor immunological response of a melanoma mice model

Meng Wang, Shi‑Ju Yan, Hong‑Tao Zhang, Nan Li, Tao Liu, Ying‑Long  Zhang, Xiao‑Xiang Li, Qiong Ma, Xiu‑Chun Qiu, Qing‑Yu Fan, Bao‑An Ma
Pages: 681-685
Published online on: 12 December 2016

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Article Open Access

Downregulation of feline sarcoma-related protein inhibits cell migration, invasion and epithelial-mesenchymal transition via the ERK/AP-1 pathway in bladder urothelial cell carcinoma

Xudong Hu, Zhiqiang Zhang, Zhaofeng Liang, Dongdong Xie, Tao Zhang, Dexin Yu, Caiyun Zhong
Pages: 686-694
Published online on: 05 December 2016

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Article Open Access

EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong‑Hui Li, Wen‑He Huang, Jun‑Dong Wu, Cai‑Wen Du, Guo‑Jun Zhang
Pages: 695-703
Published online on: 12 December 2016

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Article Open Access

Association between XRCC1 and ERCC1 single‑nucleotide polymorphisms and the efficacy of concurrent radiochemotherapy in patients with esophageal squamous cell carcinoma

Xue Huang, Changmin Liu, Yayun Cui, Heping Zhang, Yongping Liu, Xifa Zhou, Judong Luo
Pages: 704-714
Published online on: 14 December 2016

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Article Open Access

Expression of CHODL in hepatocellular carcinoma affects invasion and migration of liver cancer cells

Zejian Huang, Ning Zhang, Wenda Li, Jun Cao, Lei Zhang, Yajin Chen
Pages: 715-721
Published online on: 06 December 2016

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Article Open Access

MicroRNA‑93‑5p increases multidrug resistance in human colorectal carcinoma cells by downregulating cyclin dependent kinase inhibitor 1A gene expression

Shi‑Jun Wang, Yun‑Fei Cao, Zu‑Qing Yang, Zhi‑Yuan Jiang, Bin Cai, Jiao Guo, Sen Zhang, Xiao‑Long Zhang, Feng Gao
Pages: 722-730
Published online on: 06 December 2016

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Article Open Access

Forkhead transcription factor 1 inhibits endometrial cancer cell proliferation via sterol regulatory element‑binding protein 1

Yifang Zhang, Lili Zhang, Hengzi Sun, Qingtao Lv, Chunping Qiu, Xiaoxia Che, Zhiming Liu, Jie Jiang
Pages: 731-737
Published online on: 12 December 2016

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Article Open Access

Alkaloids of fascaplysin are effective conventional chemotherapeutic drugs, inhibiting the proliferation of C6 glioma cells and causing their death in vitro

Igor Bryukhovetskiy, Irina Lyakhova, Polina Mischenko, Elena  Milkina, Sergei  Zaitsev, Yuri Khotimchenko, Andrey Bryukhovetskiy, Alexander  Polevshchikov, Igor Kudryavtsev, Maxim Khotimchenko, Maxim Zhidkov
Pages: 738-746
Published online on: 09 December 2016

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Article Open Access

Multicenter phase II study of infusional 5‑fluorouracil (5‑FU), leucovorin, and oxaliplatin, plus biweekly cetuximab as first‑line treatment in patients with metastatic colorectal cancer (CELINE trial)

Masanori Kotake, Toru Aoyama, Yoshinori Munemoto, Kenji Doden, Masato Kataoka, Kenji Kobayashi, Genichi Nishimura, Hidehito Fujita, Keishi Nakamura, Akira Takehara, Chihiro Tanaka, Junichi Sakamoto, Naoki Nagata, Koji Oba, Ken Kondo
Pages: 747-753
Published online on: 14 December 2016

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Article Open Access

Ursolic acid sensitizes radioresistant NSCLC cells expressing HIF‑1α through reducing endogenous GSH and inhibiting HIF‑1α

Bing Song, Qian Zhang, Maohu Yu, Xinrong Qi, Gang Wang, Linlin Xiao, Qiyi Yi, Wensen Jin
Pages: 754-762
Published online on: 07 December 2016

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Article Open Access

P300 promotes migration, invasion and epithelial-mesenchymal transition in a nasopharyngeal carcinoma cell line

Zhi‑Wei Liao, Lei Zhao, Mu‑Yan Cai, Mian Xi, Li‑Ru He, Fang Yu, Tong‑Chong Zhou, Meng‑Zhong Liu
Pages: 763-769
Published online on: 13 December 2016

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Article

Autophagy impacts on oxaliplatin-induced hepatocarcinoma apoptosis via the IL-17/IL-17R-JAK2/STAT3 signaling pathway

Jinghua Wu, Jiapei Guo, Qing Cao, Yi Wang, Junmao Chen, Zhigang Wang, Zhiyong Yuan
Pages: 770-776
Published online on: 08 December 2016

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Article Open Access

Bioinformatic identification of candidate genes induced by trichostatin A in BGC-823 gastric cancer cells

Yunlong Li, Lisha Zhang, Chunfa Yang, Riheng Li, Longbin Shang, Xiaoming Zou
Pages: 777-783
Published online on: 12 December 2016

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Article Open Access

Effect of cancer/testis antigen NY‑SAR‑35 on the proliferation, migration and invasion of cancer cells

Myung‑Ha Song, Ye‑Rin Kim, Jae‑Ho Bae, Chang‑Hun Lee, Sang‑Yull Lee
Pages: 784-790
Published online on: 14 December 2016

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Article Open Access

Induction of apoptosis by FFJ‑5, a novel naphthoquinone compound, occurs via downregulation of PKM2 in A549 and HepG2 cells

Xiaoli Wei, Ming Li, Mingming Ma, Huina Jia, Yu Zhang, Wenyi Kang, Tianxiao Wang, Xiaoyan Shi
Pages: 791-799
Published online on: 20 December 2016

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Article

2‑Deoxyglucose and sorafenib synergistically suppress the proliferation and motility of hepatocellular carcinoma cells

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Pages: 800-804
Published online on: 16 December 2016

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Article

Comparative clinicopathological characteristics of colon and rectal T1 carcinoma

Katsuro Ichimasa, Shin‑Ei Kudo, Hideyuki Miyachi, Yuta Kouyama, Takemasa Hayashi, Kunihiko Wakamura, Tomokazu Hisayuki, Toyoki Kudo, Masashi Misawa, Yuichi Mori, Shingo Matsudaira, Eiji Hidaka, Shigeharu Hamatani, Fumio Ishida
Pages: 805-810
Published online on: 06 December 2016

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Article

Human antigen R as a predictive marker for response to gemcitabine‑based chemotherapy in advanced cisplatin‑resistant urothelial cancer

Yasuyoshi Miyata, Kensuke Mitsunari, Asai Akihiro, Shin‑Ichi Watanabe, Tomohiro Matsuo, Kojiro Ohba, Hideki Sakai
Pages: 811-818
Published online on: 12 December 2016

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Article

Prognostic significance of KLF4 expression in gastric cancer

Isaya Hashimoto, Takuya Nagata, Shinichi Sekine, Makoto Moriyama, Kazuto Shibuya, Shozo Hojo, Koshi Matsui, Isaku Yoshioka, Tomoyuki Okumura, Takashi Hori, Yutaka Shimada, Kazuhiro Tsukada
Pages: 819-826
Published online on: 14 December 2016

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Article

Overexpression of KAI1 inhibits retinoblastoma metastasis in vitro

Hui Yan, Xunda Ji, Jing Li, Lei Zhang, Peiquan Zhao
Pages: 827-833
Published online on: 16 December 2016

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Article

Stromal expression of Fer suppresses tumor progression in renal cell carcinoma and is a predictor of survival

Kensuke Mitsunari, Yasuyoshi Miyata, Shin‑Ichi Watanabe, Akihiro Asai, Takuji Yasuda, Shigeru Kanda, Hideki Sakai
Pages: 834-840
Published online on: 12 December 2016

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Article

Trametes robiniophila may induce apoptosis and inhibit MMPs expression in the human gastric carcinoma cell line MKN‑45

Xuening Ji, Chunxia Pan, Xiaowen Li, Yunbin Gao, Lu Xia, Xiulian Quan, Jinyan Lv, Ruoyu Wang
Pages: 841-846
Published online on: 20 December 2016

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Article

Bone metastasis from lung cancer identified by genetic profiling

Zhu‑Lin Liu, Chun Wang, Hui‑Jiao Chen, Xue Li, Li‑Jun Dai, Zhen‑Yu Ding
Pages: 847-850
Published online on: 02 December 2016

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Article

MicroRNA‑149 targets specificity protein 1 to suppress human tongue squamous cell carcinoma cell proliferation and motility

Jingxin Chen, Jimin Chen, Weizhong Li
Pages: 851-856
Published online on: 20 December 2016

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Article

Influence of gap junction intercellular communication composed of connexin 43 on the antineoplastic effect of adriamycin in breast cancer cells

Guojun Jiang, Shuying Dong, Meiling Yu, Xi Han, Chao Zheng, Xiaoguang Zhu, Xuhui Tong
Pages: 857-866
Published online on: 07 December 2016

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Article

Elevated microRNA-125b levels predict a worse prognosis in HER2-positive breast cancer patients

Yanwei Luo, Xinye Wang, Weihong Niu, Heran Wang, Qiuyuan Wen, Songqing Fan, Ran Zhao, Zheng Li, Wei Xiong, Shuping Peng, Zhaoyang Zeng, Xiaoling Li, Guiyuan Li, Ming Tan, Ming Zhou
Pages: 867-874
Published online on: 12 December 2016

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Article

Wild-type p53-induced phosphatase 1 is a prognostic marker and therapeutic target in bladder transitional cell carcinoma

Zhi‑Peng Wang, Shu‑Yuan Chen, Ye Tian
Pages: 875-880
Published online on: 08 December 2016

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Article

Patients with normal‑range CA19‑9 levels represent a distinct subgroup of pancreatic cancer patients

Guopei Luo, Kaizhou Jin, Meng Guo, He Cheng, Zuqiang Liu, Zhiwen Xiao, Yu Lu, Jiang Long, Liang Liu, Jin Xu, Chen Liu, Yutang Gao, Quanxing Ni, Xianjun Yu
Pages: 881-886
Published online on: 14 December 2016

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Article Open Access

Gastrointestinal stromal tumor with a PDGFRA mutation masquerading as gastric plexiform fibromyxoma: A comparative clinicopathological study of two cases

Jun Zhou, Jingjing Xu, Guozhong Jiang, Yihui Ma, Jingwen Qi, Wencai Li, Dandan Zhang
Pages: 887-892
Published online on: 12 December 2016

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Article

Potential regulation of glioma through the induction of apoptosis signaling via Egl‑9 family hypoxia‑inducible factor 3

Ke Mao, Chao You, Ding Lei, Heng Zhang
Pages: 893-897
Published online on: 14 December 2016

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Article

CD147 promotes the proliferation, invasiveness, migration and angiogenesis of human lung carcinoma cells

Shaoxing Yang, Fei Qi, Chuanhao Tang, Hong Wang, Haifeng Qin, Xiaoyan Li, Jianjie Li, Weixia Wang, Changyun Zhao, Hongjun Gao
Pages: 898-904
Published online on: 14 December 2016

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Article

Clinical significance of platelet‑derived growth factor receptor‑β gene expression in stage II/III gastric cancer with S‑1 adjuvant chemotherapy

Akio Higuchi, Takashi Oshima, Kazue Yoshihara, Kentaro Sakamaki, Toru Aoyama, Nobuyasu Suganuma, Naoto Yamamoto, Tsutomu Sato, Haruhiko Cho, Manabu Shiozawa, Takaki Yoshikawa, Yasushi Rino, Chikara Kunisaki, Toshio Imada, Munetaka Masuda
Pages: 905-911
Published online on: 14 December 2016

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Article

Reproducibility of the EGFR immunohistochemistry scores for tumor samples from patients with advanced non-small cell lung cancer

Alejandro Avilés‑Salas, Saé Muñiz‑Hernández, Héctor Aquiles Maldonado‑Martínez, José G. Chanona‑Vilchis, Laura‑Alejandra Ramírez‑Tirado, Norma Hernández‑Pedro, Rita Dorantes‑Heredia, José Manuel Ruíz‑Morales, Daniel Motola‑Kuba, Oscar Arrieta
Pages: 912-920
Published online on: 16 December 2016

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Article

Inhibition of store‑operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate

Wei Huang, Caiping Ren, Guoling Huang, Jie Liu, Weidong Liu, Lei Wang, Bin Zhu, Xiangling Feng, Jia Shi, Jinlong Li, Xiaomeng Xia, Wei Jia, Jiawen Chen, Yuxiang Chen, Xingjun Jiang
Pages: 921-929
Published online on: 07 December 2016

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Article

Regulation of cell migration via the EGFR signaling pathway in oral squamous cell carcinoma cells

Yuichi Ohnishi, Hiroki Yasui, Kenji Kakudo, Masami Nozaki
Pages: 930-936
Published online on: 14 December 2016

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Article

Characteristic expression of fukutin in gastric cancer among atomic bomb survivors

Trang T.B. Pham, Naohide Oue, Manabu Yamamoto, Megumu Fujihara, Teruyoshi Ishida, Shoichiro Mukai, Naoya Sakamoto, Kazuhiro Sentani, Wataru Yasui
Pages: 937-941
Published online on: 20 December 2016

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Article

DHX32 expression is an indicator of poor breast cancer prognosis

Meng Wang, Guojun Zhang, Yajie Wang, Ruimin Ma, Limin Zhang, Hong Lv, Fang Fang, Xixiong Kang
Pages: 942-948
Published online on: 14 December 2016

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Article

TCN, an AKT inhibitor, exhibits potent antitumor activity and enhances radiosensitivity in hypoxic esophageal squamous cell carcinoma in vitro and in vivo

Qing Guo, Jia He, Feng Shen, Wei Zhang, Xi Yang, Chi Zhang, Qu Zhang, Jun‑Xing Huang, Zheng‑Dong Wu, Xin‑Chen Sun, Sheng‑Bin Dai
Pages: 949-954
Published online on: 20 December 2016

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Article

Interleukin‑1β activates focal adhesion kinase and Src to induce matrix metalloproteinase‑9 production and invasion of MCF‑7 breast cancer cells

Naing Naing Mon, Takeshi Senga, Satoko Ito
Pages: 955-960
Published online on: 20 December 2016

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Article

Molecular mechanisms of cholangiocarcinoma cell inhibition by medicinal plants

Surang Leelawat, Kawin Leelawat
Pages: 961-966
Published online on: 12 December 2016

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Article

Hypoxia regulates CD44 expression via hypoxia-inducible factor-1α in human gastric cancer cells

Gai Liang, Shuang Li, Wei Du, Qinghua Ke, Jun Cai, Jiyuan Yang
Pages: 967-972
Published online on: 08 December 2016

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Article

Pro-apoptotic and anti-proliferative effects of corn silk extract on human colon cancer cell lines

Hao Guo, Hong Guan, Wenqin Yang, Han Liu, Huiling Hou, Xue Chen, Zhenyan Liu, Chuangang Zang, Yuchao Liu, Jicheng Liu
Pages: 973-978
Published online on: 05 December 2016

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Case Report

Complete response to capecitabine in a frail, elderly patient with metastatic colorectal cancer: A case report

Morena Fasano, Alessio Fabozzi, Guido Giordano, Filippo Venturini, Gaetano Aurilio, Flavia Cantile, Teresa Fabozzi, Vincenzo Ricci, Giuseppe Santabarbara, Floriana Morgillo, Fortunato Ciardiello, Ferdinando De Vita
Pages: 979-983
Published online on: 20 December 2016

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Article

Sorafenib therapy following resection prolongs disease‑free survival in patients with advanced hepatocellular carcinoma at a high risk of recurrence

Yadi Liao, Yun Zheng, Wei He, Qijiong Li, Jingxian Shen, Jian Hong, Ruhai Zou, Jiliang Qiu, Binkui Li, Yunfei Yuan
Pages: 984-992
Published online on: 20 December 2016

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Article

Single nucleotide polymorphisms of the haptoglobin gene in non-small cell lung cancer treated with personalized peptide vaccination

Kayoko Waki, Teppei Yamada, Koichi Yoshiyama, Yasuhiro Terazaki, Shinjiro Sakamoto, Shunichi Sugawara, Shinzo Takamori, Kyogo Itoh, Akira Yamada
Pages: 993-999
Published online on: 07 December 2016

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Article

Prognostic significance of the preoperative lymphocyte‑to‑monocyte ratio in patients with colorectal cancer

Masatsune Shibutani, Kiyoshi Maeda, Hisashi Nagahara, Yasuhito Iseki, Tetsuro Ikeya, Kosei Hirakawa
Pages: 1000-1006
Published online on: 12 December 2016

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Article

Arctigenin, a natural lignan compound, induces G0/G1 cell cycle arrest and apoptosis in human glioma cells Retraction in /10.3892/ol.2023.14173

Aisha Maimaitili, Zunhua Shu, Xiaojiang Cheng, Kadeer Kaheerman, Alifu Sikandeer, Weimin Li
Pages: 1007-1013
Published online on: 08 December 2016

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Article

Primary breast lymphoma: A single center study

Na Zhang, Caineng Cao, Yuan Zhu, Peng Liu, Luying Liu, Ke Lu, Jialin Luo, Ning Zhou
Pages: 1014-1018
Published online on: 12 December 2016

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Article

Pinus massoniana bark extract inhibits migration of the lung cancer A549 cell line

Ping Mao, Ershao Zhang, Yang Chen, Likun Liu, Daqing Rong, Qingfeng Liu, Weiling Li
Pages: 1019-1023
Published online on: 16 December 2016

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Article

Apigenin enhances the cisplatin cytotoxic effect through p53‑modulated apoptosis

Rui Liu, Ping Ji, Bin Liu, Haishi Qiao, Xia Wang, Likun Zhou, Ting Deng, Yi Ba
Pages: 1024-1030
Published online on: 14 December 2016

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Pathological response to neoadjuvant chemotherapy and survival in patients with breast cancer: A multicentric retrospective study

Evrard Narcisse Séka, Danielle Asmao Traoré, Corneille Téa Saki, Kadjatou Traoré, Amara Gozana Tuo, Brahima Doukouré
Article Number: 93
Published online on: 02 January 2026

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Case Report

Curative surgery enabled by radiotherapy in rectal cancer: A case report

Sofia E. Sánchez‑De‑Toca Gómez, Fernando Mendoza Moreno, Patricia Urbón Sánchez, Felix Mañes Jiménez, Yousef Allaoua Massaoui, Lucas Casalduero García, Pablo Barat Betrán, Alejandra Julia Lopez Marsellá, María Mejías Ledesma, Alberto Vilar Tabanera, Manuel Diez Alonso, Alberto Gutiérrez Calvo
Article Number: 92
Published online on: 31 December 2025

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Case Report Open Access

Metastatic urothelial carcinoma of the urethra and glans penis with reported implantation via the urine: A case report

Piotr Kalinowski, Paweł Nalej, Beata Grochulska‑Nalazek, Tomasz Kalinowski, Tomasz Demkow, Olga Kuczkiewicz‑Siemion, Roman Romaniuk
Article Number: 91
Published online on: 31 December 2025

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Article Open Access

Serum expression levels of HOTAIR and miR‑646 in endometrial cancer

Rizki̇ Hari̇smunandar, Hande Karpuzoğlu, Yağmur Mi̇nareci̇, Hamdullah Sözen, Samet Topuz, Canan Küçükgergi̇n, A. Fati̇h Aydin
Article Number: 90
Published online on: 30 December 2025

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Article

Predictive value analysis of CEA, CA125 and CYFRA21‑1 levels in evaluating the efficacy of tislelizumab combined with gemcitabine‑cisplatin chemotherapy in patients with advanced non‑small cell lung cancer

Langyue Wang, Tianyu Gou, Yang Cui, Meng Li, Yu Wang
Article Number: 89
Published online on: 30 December 2025

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Case Report Open Access

Individualized management strategies for advanced non‑small cell lung cancer with EGFR exon 19 deletion and L861Q compound mutations based on circulating tumor DNA monitoring: A case report

Xiaobang Zhu, Ye Sun, Ruirui Cai, Wenbin Zhang, Xiangwei Zhang, Ailing Song, Xiaoyan Chen, Cuicui Liu, Jianping Zhou
Article Number: 88
Published online on: 23 December 2025

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Case Report

Metastasis of lung adenocarcinoma to follicular thyroid carcinoma combined with papillary thyroid carcinoma in the contralateral lobe: A case report

Cuicui Wang, Yihang Yang, Liquan Bi, Xiaohong Liu
Article Number: 87
Published online on: 23 December 2025

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Article

Proteins Lamin A and SUN1 are exclusively decreased in nuclear grade 4 clear cell renal cell carcinoma

Rio Shibanuma, Sayaka Kobayashi, Momoka Konno, Rio Kaneko, Yoshimi Nishijima, Hayato Ikota, Masashi Nomura, Kazuhiro Suzuki, Hideaki Yokoo, Masanao Saio
Article Number: 86
Published online on: 23 December 2025

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Article Open Access

Extended cycles of anti‑GD2 antibody dinutuximab beta treatment combined with chemotherapy in patients with relapsed or refractory neuroblastoma: A retrospective study

Zhiqi Gong, Suyi Kang, Chuanfeng Bai, Yang Li, Xuedi Yu, Kun Shang, Yixiang Song, Fangfang Cheng, Jingfu Wang
Article Number: 85
Published online on: 23 December 2025

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Case Report Open Access

Primary intracranial extraskeletal myxoid chondrosarcoma in a teenager with unusual frontal location and surgical complications: A case report and literature review

Helu Wang, Fang Wang, Hongtao Zhang
Article Number: 84
Published online on: 19 December 2025

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Article Open Access

Estrogen receptor α expression in tumor‑infiltrating lymphocytes from patients with endometrial cancer

Marcin A. Jedryka, Anna Slawek, Paulina Kubik, Daria Lorek, Anna Ewa Kedzierska, Andrzej Czekanski, Rafał Matkowski, Anna Chelmonska-Soyta
Article Number: 83
Published online on: 19 December 2025

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Case Report Open Access

Systemic treatment for a young patient with stage IV melanoma: A case report

Xiaoyu Huang, Lianhai Zhao, Pingan Wang, Dong Xue
Article Number: 82
Published online on: 19 December 2025

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Article Open Access

High expression of G3BP1 is associated with poor prognosis in breast invasive carcinoma

Jingjing Li, Zhiqiang Zong, Jian Shen, Jiahao Wang, Xuan Zhou, Wei Shi, Jia Li, Hong Zhao, Yunwen Yan, Fanfan Li
Article Number: 81
Published online on: 18 December 2025

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Article

DHX15 overexpression suppresses colorectal cancer cell line proliferation

Yuki Ii, Kosuke Saita, Toshiro Iwagawa, Shingo Ito, Kiichi Sugimoto, Kazuhiro Sakamoto, Sumiko Watanabe
Article Number: 80
Published online on: 18 December 2025

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Article

Construction of a novel prediction model based on albumin‑hemoglobin score and serum microRNA-497‑5p for prognosis of patients with stage II‑III colorectal cancer

Qian Wang, Hailiang Wang, Lingling Liu, Zhen Wang
Article Number: 79
Published online on: 17 December 2025

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Article Open Access

Dual role of IFNγ in reprogramming the undifferentiated pleomorphic sarcoma cell line JBT19 towards cytotoxic chemotherapy and antitumor immunity

Pavla Taborska, Dmitry Stakheev, Daniel Smrz
Article Number: 78
Published online on: 16 December 2025

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Article Open Access

Identifying myosin heavy chain 11 as a predictive biomarker of prostate cancer progression and antiandrogen resistance

Cong Chen, Zhi Li, Jianliang Shen, Guilin Xie, Liangming Pan
Article Number: 77
Published online on: 15 December 2025

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Retraction Open Access

[Retracted] Activation of GPER by E2 promotes proliferation, invasion and migration of breast cancer cells by regulating the miR‑124/CD151 pathway

Huaicheng Yang, Congyu Wang, Heqiang Liao, Qi Wang
Article Number: 76
Published online on: 15 December 2025

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Article Open Access

Identification of non‑oncology drugs with activity against inflammatory and triple‑negative breast cancer cell lines

Syed Ahmad, Sara Kandil, Kevin P. Williams, John E. Scott
Article Number: 75
Published online on: 15 December 2025

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Correction Open Access

[Corrigendum] Targeted silencing of CXCR4 inhibits epithelial‑mesenchymal transition in oral squamous cell carcinoma

Yuansheng Duan, Shu Zhang, Longlong Wang, Xuan Zhou, Qinghua He, Su Liu, Kai Yue, Xudong Wang
Article Number: 74
Published online on: 10 December 2025

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Case Report Open Access

Epstein‑Barr virus+ inflammatory follicular dendritic cell sarcoma with clonal immunoglobulin heavy chain gene rearrangement: A case report and literature review

Qian Ye, Juan Zhao, Jiao He, Weishan Zhang
Article Number: 73
Published online on: 09 December 2025

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Article Open Access

A prognostic model for human papillomavirus‑negative head and neck squamous cell carcinoma based on a novel ferroptosis‑related gene signature: Development, validation and elucidation of its relationship with the immune microenvironment

Jiao Li, Nurhayu Ab Rahman, Suharni Mohamad, Guang Yang
Article Number: 72
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] Knockdown of lncRNA NUTM2A‑AS1 inhibits lung adenocarcinoma cell viability by regulating the miR‑590‑5p/METTL3 axis

Jie Wang, Jingyun Zha, Xiaolin Wang
Article Number: 71
Published online on: 08 December 2025

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Case Report Open Access

Primary bone marrow diffuse large B‑cell lymphoma with secondary myelofibrosis: A case report

Jing Yang, Sheng-Ke Tu, Hui Peng, Yuan-Yuan Peng, Min Li, Kui Song
Article Number: 70
Published online on: 05 December 2025

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Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Article Open Access

Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Article Open Access

Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Article Open Access

Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Article Open Access

Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Article Open Access

Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑Zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 31 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Prognostic value of glioma‑associated oncogene homolog 1 and SET domain‑containing protein 2 immunohistochemical scores in locally advanced cervical cancer

Erick De La Cruz‑Hernández, Gabriela Carolina Morales‑Sandoval, Marcela Lizano, Alejandro Avilés‑Salas, Leonardo Josué Castro‑Muñoz, Adela Carrillo‑García, Maria Del Pilar Ramos‑Godinez, Jaime Alberto Coronel‑Martinez, Adriana Contreras‑Paredes
Article Number: 105
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Clinical significance of bromodomain‑containing protein 7 and its association with tumor progression in prostate cancer

Yong Liang, Baiping Dong, Jiangwei Shen, Caosheng Ma, Zhongping Ma
Article Number: 104
Published online on: 12 January 2026

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Article Open Access

LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance

Cairong Zhang, Jie Ma, Wenling Wang, Min Guo, Cuiliu Han, Madinamu Sadike, Kaichun Zhu
Article Number: 103
Published online on: 12 January 2026

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Article Open Access

Circular RNA hsa_circ_0006168: A potential biomarker for the diagnosis and prognosis of prostate cancer

Ye Ding, Mao-Tong Liu, Na Yu, Liusijie Gao, Li-Ping Chen
Article Number: 102
Published online on: 09 January 2026

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Review Open Access

Meta‑analysis of the clinical efficacy of anti‑PD‑1/L1 + paclitaxel/albumin‑paclitaxel + platinum vs. paclitaxel/albumin‑paclitaxel + platinum in the treatment of patients with advanced non‑small cell lung cancer

Feng Li, Suyun Yan, Liping Liu
Article Number: 101
Published online on: 09 January 2026

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Review Open Access

Progress in perioperative immunotherapy for lung cancer and analysis of therapy (Review)

Xiao Ma, Gaofeng Li, Heng Li, Lanjun Li, Hanting Zhao, Zhiqing Liu
Article Number: 100
Published online on: 09 January 2026

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Correction Open Access

[Corrigendum] p53 positively regulates the expression of cancer stem cell marker CD133 in HCT116 colon cancer cells

Xia Chen, Hua Guan, Xiao-Dan Liu, Da-Fei Xie, Yu Wang, Teng Ma, Bo Huang, Ping-Kun Zhou
Article Number: 99
Published online on: 08 January 2026

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Case Report Open Access

High‑intensity focused ultrasound in the multimodal treatment of colorectal cancer liver metastases: A case report

Yuanhong Yang, Hao Zhang, Yifan Shen, Fan Yang, Dan Zhao, Yujie Lin, Guohua Huang
Article Number: 98
Published online on: 07 January 2026

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Article Open Access

Exosomal microRNA‑448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis

Yuankun Chen, Tiantian Zhu, Fang Chen, Mingyue Niu, Haifeng Wu, Qiuping Wu, Zheng Wang, Wenting Li
Article Number: 97
Published online on: 07 January 2026

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Article

Diagnostic value of magnetic resonance imaging in preoperative evaluation of cervical cancer and analysis of pathological features

Xiaofei Cai, Xinjian Lu, Jinjun Yang, Xinxue Wei, Wenjing Yue, Yunqing Ban
Article Number: 96
Published online on: 07 January 2026

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Retraction Open Access

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk‑ChA‑1 and Mz‑ChA‑1 cell growth by inducing caspase‑dependent apoptosis and downregulation of survivin and Bcl‑2 expression

Fei Zhong, Jing Yang, Zhu-Ting Tong, Liu-Liu Chen, Lu-Lu Fan, Fang Wang, Xia-Li Zha, Jun Li
Article Number: 95
Published online on: 07 January 2026

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Article Open Access

Prognosis of liver transplantation and hepatectomy in patients with hepatocellular carcinoma meeting the Milan criteria: A systematic review and meta‑analysis

Jiling Wang, Zheng Pan, Yongzheng Wang, Yanshuo Ye, Wei Li
Article Number: 94
Published online on: 05 January 2026

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