|
1
|
Siegel R, Ward E, Brawley O and Jemal A:
Cancer statistics, 2011: The impact of eliminating socioeconomic
and racial disparities on premature cancer deaths. CA Cancer J
Clin. 61:212–236. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Bernzweig J, Heiniger B, Prasain K, Lu J,
Hua DH and Nguyen TA: Anti-breast cancer agents, quinolines,
targeting gap junction. Med Chem. 7:448–453. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Zhang S, Chen Y, Guo W, Yuan L, Zhang D,
Xu Y, Nemeth E, Ganz T and Liu S: Disordered hepcidin-ferroportin
signaling promotes breast cancer growth. Cell Signal. 26:2539–2550.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Li WJ, Zhong SL, Wu YJ, Xu WD, Xu JJ, Tang
JH and Zhao JH: Systematic expression analysis of genes related to
multidrug-resistance in isogenic docetaxel- and
adriamycin-resistant breast cancer cell lines. Mol Biol Rep.
40:6143–6150. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Cao B, Li M, Zha W, Zhao Q, Gu R, Liu L,
Shi J, Zhou J, Zhou F, Wu X, et al: Metabolomic approach to
evaluating adriamycin pharmacodynamics and resistance in breast
cancer cells. Metabolomics. 9:960–973. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wang J, Wu L, Kou L, Xu M, Sun J, Wang Y,
Fu Q, Zhang P and He Z: Novel nanostructured enoxaparin sodium-PLGA
hybrid carriers overcome tumor multidrug resistance of doxorubicin
hydrochloride. Int J Pharm. 513:218–226. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Gao M, Xu Y and Qiu L: Sensitization of
multidrug-resistant malignant cells by liposomes co-encapsulating
doxorubicin and chloroquine through autophagic inhibition. J
Liposome Res. June 7–2016.(Epub ahead of print). View Article : Google Scholar
|
|
8
|
Wei CJ, Xu X and Lo CW: Connexins and cell
signaling in development and disease. Annu Rev Cell Dev Biol.
20:811–838. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Trosko JE and Chang CC: Mechanism of
up-regulated gap junctional intercellular communication during
chemoprevention and chemotherapy of cancer. Mutat Res 480–481.
219–229. 2001. View Article : Google Scholar
|
|
10
|
Trosko JE and Ruch RJ: Gap junctions as
targets for cancer chemoprevention and chemotherapy. Curr Drug
Targets. 3:465–482. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Yu M, Zhang C, Li L, Dong S, Zhang N and
Tong X: Cx43 reverses the resistance of A549 lung adenocarcinoma
cells to cisplatin by inhibiting EMT. Oncol Rep. 31:2751–2758.
2014.PubMed/NCBI
|
|
12
|
Li Z, Zhou Z, Welch DR and Donahue HJ:
Expressing connexin 43 in breast cancer cells reduces their
metastasis to lungs. Clin Exp Metastasis. 25:893–901. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Saez JC, Berthoud VM, Branes MC, Martinez
AD and Beyer EC: Plasma membrane channels formed by connexins:
Their regulation and functions. Physiol Rev. 83:1359–1400. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
McLachlan E, Shao Q and Laird DW:
Connexins and gap junctions in mammary gland development and breast
cancer progression. J Membr Biol. 218:107–121. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Choudhary M, Naczki C, Chen W, Barlow KD,
Case LD and Metheny-Barlow LJ: Tumor-induced loss of mural Connexin
43 gap junction activity promotes endothelial proliferation. BMC
Cancer. 15:4272015. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Aasen T: Connexins: Junctional and
non-junctional modulators of proliferation. Cell Tissue Res.
360:685–699. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Czyż J, Szpak K and Madeja Z: The role of
connexins in prostate cancer promotion and progression. Nat Rev
Urol. 9:274–282. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Qin H, Shao Q, Curtis H, Galipeau J,
Belliveau DJ, Wang T, Alaoui-Jamali MA and Laird DW: Retroviral
delivery of connexin genes to human breast tumor cells inhibits in
vivo tumor growth by a mechanism that is independent of significant
gap junctional intercellular communication. J Biol Chem.
277:29132–29138. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
He B, Tong X, Wang L, Wang Q, Ye H, Liu B,
Hong X, Tao L and Harris AL: Tramadol and flurbiprofen depress the
cytotoxicity of cisplatin via their effects on gap junctions. Clin
Cancer Res. 15:5803–5810. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Hong X, Wang Q, Yang Y, Zheng S, Tong X,
Zhang S, Tao L and Harris AL: Gap junctions propagate opposite
effects in normal and tumor testicular cells in response to
cisplatin. Cancer Lett. 317:165–171. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Tong X, Dong S, Yu M, Wang Q and Tao L:
Role of heteromeric gap junctions in the cytotoxicity of cisplatin.
Toxicology. 310:53–60. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Huang F, Li S, Gan X, Wang R and Chen Z:
Propofol inhibits gap junctions by attenuating sevoflurane-induced
cytotoxicity against rat liver cells in vitro. Eur J Anaesthesiol.
31:219–224. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Tong XH, Dong SY, Jiang GJ and Fan GF:
Influence of Cx26/Cx32 gap junction channel on antineoplastic
effect of etoposide in Hela cells. Nan Fang Yi Ke Da Xue Xue Bao.
32:329–332. 2012.(In Chinese). PubMed/NCBI
|
|
24
|
Babaoglu M, Zumrutbas AE, Acar IC, Hatip
FB, Kucukatay V, Eskicorapci S and Aybek Z: Gap junction expression
and the effects of gap junction inhibitors in overactive bladder
models: Does ovariectomy have a role? Int Urol Nephrol.
45:1001–1008. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Talhouk R, Tarraf C, Kobrossy L, Shaito A,
Bazzi S, Bazzoun D and El-Sabban M: Modulation of Cx43 and gap
junctional intercellular communication by androstenedione in rat
polycystic ovary and granulosa cells in vitro. J Reprod Infertil.
13:21–32. 2012.PubMed/NCBI
|
|
26
|
Wu J, Taylor RN and Sidell N: Retinoic
acid regulates gap junction intercellular communication in human
endometrial stromal cells through modulation of the phosphorylation
status of connexin 43. J Cell Physiol228. 903–910. 2013. View Article : Google Scholar
|
|
27
|
Bier A, Oviedo-Landaverde I, Zhao J,
Mamane Y, Kandouz M and Batist G: Connexin43 pseudogene in breast
cancer cells offers a novel therapeutic target. Mol Cancer Ther.
8:786–793. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Shao Q, Wang H, McLachlan E, Veitch GI and
Laird DW: Down-regulation of Cx43 by retroviral delivery of small
interfering RNA promotes an aggressive breast cancer cell
phenotype. Cancer Res. 65:2705–2711. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Ablasser A, Schmid-Burgk JL, Hemmerling I,
Horvath GL, Schmidt T, Latz E and Hornung V: Cell intrinsic
immunity spreads to bystander cells via the intercellular transfer
of cGAMP. Nature. 503:530–534. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Vliagoftis H, Ebeling C, Ilarraza R,
Mahmudi-Azer S, Abel M, Adamko D, Befus AD and Moqbel R: Connexin
43 expression on peripheral blood eosinophils: Role of gap
junctions in transendothelial migration. Biomed Res Int.
2014:8032572014. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Hsiao PJ, Jao JC, Tsai JL, Chang WT, Jeng
KS and Kuo KK: Inorganic arsenic trioxide induces gap junction loss
in association with the downregulation of connexin43 and E-cadherin
in rat hepatic "stem-like" cells. Kaohsiung J Med Sci. 30:57–67.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zhang D, Chen C, Li Y, Fu X, Xie Y, Li Y
and Huang Y: Cx31.1 acts as a tumour suppressor in non-small cell
lung cancer (NSCLC) cell lines through inhibition of cell
proliferation and metastasis. J Cell Mol Med. 16:1047–1059. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Teleki I, Krenacs T, Szasz MA, Kulka J,
Wichmann B, Leo C, Papassotiropoulos B, Riemenschnitter C, Moch H
and Varga Z: The potential prognostic value of connexin 26 and 46
expression in neoadjuvant-treated breast cancer. BMC Cancer.
13:502013. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wu JF, Ji J, Dong SY, Li BB, Yu ML, Wu DD,
Tao L and Tong XH: Gefitinib enhances oxaliplatin-induced apoptosis
mediated by Src and PKC-modulated gap junction function. Oncol Rep.
Oct 11–2016.(Epub ahead of print). View Article : Google Scholar
|
|
35
|
Yu BB, Dong SY, Yu ML, Jiang GJ, Ji J and
Tong XH: Total flavonoids of litsea coreana enhance the
cytotoxicity of oxaliplatin by increasing gap junction
intercellular communication. Biol Pharm Bull. 37:1315–1322. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Hong X, Sin WC, Harris AL and Naus CC: Gap
junctions modulate glioma invasion by direct transfer of microRNA.
Oncotarget. 6:15566–15577. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Zhou JZ, Riquelme MA, Gu S, Kar R, Gao X,
Sun L and Jiang JX: Osteocytic connexin hemichannels suppress
breast cancer growth and bone metastasis. Oncogene. 35:5597–5607.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Chiu HW, Yeh YL, Wang YC, Huang WJ, Chen
YA, Chiou YS, Ho SY, Lin P and Wang YJ: Suberoylanilide hydroxamic
acid, an inhibitor of histone deacetylase, enhances
radiosensitivity and suppresses lung metastasis in breast cancer in
vitro and in vivo. PLoS One. 8:e763402013. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Shishido SN and Nguyen TA: Gap junction
enhancer increases efficacy of cisplatin to attenuate mammary tumor
growth. PLoS One. 7:e449632012. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Ferraroni M, Bazzicalupi C, Bilia AR and
Gratteri P: X-Ray diffraction analyses of the natural isoquinoline
alkaloids Berberine and Sanguinarine complexed with double helix
DNA d (CGTACG). Chem Commun (Camb). 47:4917–4919. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Sun H, Yang S, Li J, Zhang Y, Gao D and
Zhao S: Caspase-independent cell death mediated by
apoptosis-inducing factor (AIF) nuclear translocation is involved
in ionizing radiation induced HepG2 cell death. Biochem Biophys Res
Commun. 472:137–143. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Jo GH, Bögler O, Chwae YJ, Yoo H, Lee SH,
Park JB, Kim YJ, Kim JH and Gwak HS: Radiation-induced autophagy
contributes to cell death and induces apoptosis partly in malignant
glioma cells. Cancer Res Treat. 47:221–241. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Kong H, Liu X, Yang L, Qi K, Zhang H,
Zhang J, Huang Z and Wang H: All-trans retinoic acid enhances
bystander effect of suicide gene therapy in the treatment of breast
cancer. Oncol Rep. 35:1868–1874. 2016.PubMed/NCBI
|
|
44
|
Yakovlev VA: Role of nitric oxide in the
radiation-induced bystander effect. Redox Biol. 6:396–400. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Prise KM and O'Sullivan JM:
Radiation-induced bystander signalling in cancer therapy. Nat Rev
Cancer. 9:351–360. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Li S, Gu C, Gao Y, Amano S, Koizumi S,
Tokuyama T and Namba H: Bystander effect in glioma suicide gene
therapy using bone marrow stromal cells. Stem Cell Res. 9:270–276.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Leten C, Trekker J, Struys T, Roobrouck
VD, Dresselaers T, Velde GV, Lambrichts I, Verfaillie CM and
Himmelreich U: Monitoring the Bystander Killing Effect of Human
Multipotent Stem Cells for Treatment of Malignant Brain Tumors.
Stem Cells Int. 2016:40950722016. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Li S, Gao Y, Pu K, Ma L, Song X and Liu Y:
All-trans retinoic acid enhances bystander effect of suicide-gene
therapy against medulloblastomas. Neurosci Lett. 503:115–119. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Yang J, Liu TJ, Jiang YX and Lu Y: ATRA
enhances the bystander effect of suicide gene therapy driven by the
specific promoter LEP 503 in human lens epithelial cells. Mol Vis.
18:2053–2066. 2012.PubMed/NCBI
|
|
50
|
Nakase T, Fushiki S and Naus CC:
Astrocytic gap junctions composed of connexin 43 reduce apoptotic
neuronal damage in cerebral ischemia. Stroke. 34:1987–1993. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Conklin CM, Bechberger JF, MacFabe D,
Guthrie N, Kurowska EM and Naus CC: Genistein and quercetin
increase connexin43 and suppress growth of breast cancer cells.
Carcinogenesis. 28:93–100. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Conklin C, Huntsman D, Yorida E, Makretsov
N, Turbin D, Bechberger JF, Sin WC and Naus CC: Tissue microarray
analysis of connexin expression and its prognostic significance in
human breast cancer. Cancer Lett. 255:284–294. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Sulkowska U, Wincewicz A, Kanczuga-Koda L,
Koda M and Sulkowski S: Eventual proapoptotic or anti-apoptotic
impact of aberrantly expressed Cx43 and Cx26 can depend on ER-alpha
overexpression in human endometrioid adenocarcinoma. Gynecol
Endocrinol. 31:604–608. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Tarasewicz E, Rivas L, Hamdan R, Dokic D,
Parimi V, Bernabe BP, Thomas A, Shea LD and Jeruss JS: Inhibition
of CDK-mediated phosphorylation of Smad3 results in decreased
oncogenesis in triple negative breast cancer cells. Cell Cycle.
13:3191–3201. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Collins DC, Cocchiglia S, Tibbitts P,
Solon G, Bane FT, McBryan J, Treumann A, Eustace A, Hennessy B,
Hill AD and Young LS: Growth factor receptor/steroid receptor cross
talk in trastuzumab-treated breast cancer. Oncogene. 34:525–530.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Ciocca DR and Elledge R: Molecular markers
for predicting response to tamoxifen in breast cancer patients.
Endocrine. 13:1–10. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Saito T, Tanaka R, Wataba K, Kudo R and
Yamasaki H: Overexpression of estrogen receptor-alpha gene
suppresses gap junctional intercellular communication in
endometrial carcinoma cells. Oncogene. 23:1109–1116. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Zhao K, Kuperman L, Geimonen E and
Andersen J: Progestin represses human connexin43 gene expression
similarly in primary cultures of myometrial and uterine leiomyoma
cells. Biol Reprod. 54:607–615. 1996. View Article : Google Scholar : PubMed/NCBI
|
