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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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April-2017 Volume 13 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report Open Access

De novo myoepithelial carcinoma with multiple metastases arising from a submandibular salivary gland: A case report

  • Authors:
    • Karina Cecília Panelli Santos
    • Hidenobu Matsuzaki
    • Teruhisa Unetsubo
    • Shimo Tsuyoshi
    • Hitoshi Nagatsuka
    • Jun‑Ichi Asaumi

  • View Affiliations / Copyright

    Affiliations: Department of Oral and Maxillofacial Radiology, Field of Tumor Biology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Kita‑ku, Okayama 700‑8558, Japan, Department of Oral Diagnosis and Dentomaxillofacial Radiology, Okayama University Hospital, Kita‑ku, Okayama 700‑8558, Japan, Department of Oral and Maxillofacial Surgery and Biopathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Kita‑ku, Okayama 700‑8558, Japan, Department of Oral Pathology and Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Kita‑ku, Okayama 700‑8558, Japan
    Copyright: © Panelli Santos et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2679-2683
    |
    Published online on: February 28, 2017
       https://doi.org/10.3892/ol.2017.5783
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Abstract

Salivary gland carcinomas are rare tumors, representing ~0.5% of all malignancies. Myoepithelioma is also uncommon, representing ~1% of all salivary gland tumors. Myoepithelial carcinoma (MC) is even rarer, representing 0.2 to 0.6% of all salivary gland tumors. We herein report a case of MC with multiple metastases arising from a submandibular gland in a 71-year-old male patient and present the associated imaging findings. The patient was considered to have a de novo type of myoepithelial carcinoma, which is reportedly associated with higher malignancy than the transformation type of the disease (i.e., a malignant change from pleomorphic adenoma or myoepithelioma). This was reflected in the multiple lung and bone metastases sites and strong positivity for p53 and Ki‑67.

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Copy and paste a formatted citation
Spandidos Publications style
Panelli Santos KC, Matsuzaki H, Unetsubo T, Tsuyoshi S, Nagatsuka H and Asaumi JI: De novo myoepithelial carcinoma with multiple metastases arising from a submandibular salivary gland: A case report. Oncol Lett 13: 2679-2683, 2017.
APA
Panelli Santos, K.C., Matsuzaki, H., Unetsubo, T., Tsuyoshi, S., Nagatsuka, H., & Asaumi, J. (2017). De novo myoepithelial carcinoma with multiple metastases arising from a submandibular salivary gland: A case report. Oncology Letters, 13, 2679-2683. https://doi.org/10.3892/ol.2017.5783
MLA
Panelli Santos, K. C., Matsuzaki, H., Unetsubo, T., Tsuyoshi, S., Nagatsuka, H., Asaumi, J."De novo myoepithelial carcinoma with multiple metastases arising from a submandibular salivary gland: A case report". Oncology Letters 13.4 (2017): 2679-2683.
Chicago
Panelli Santos, K. C., Matsuzaki, H., Unetsubo, T., Tsuyoshi, S., Nagatsuka, H., Asaumi, J."De novo myoepithelial carcinoma with multiple metastases arising from a submandibular salivary gland: A case report". Oncology Letters 13, no. 4 (2017): 2679-2683. https://doi.org/10.3892/ol.2017.5783
Copy and paste a formatted citation
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Spandidos Publications style
Panelli Santos KC, Matsuzaki H, Unetsubo T, Tsuyoshi S, Nagatsuka H and Asaumi JI: De novo myoepithelial carcinoma with multiple metastases arising from a submandibular salivary gland: A case report. Oncol Lett 13: 2679-2683, 2017.
APA
Panelli Santos, K.C., Matsuzaki, H., Unetsubo, T., Tsuyoshi, S., Nagatsuka, H., & Asaumi, J. (2017). De novo myoepithelial carcinoma with multiple metastases arising from a submandibular salivary gland: A case report. Oncology Letters, 13, 2679-2683. https://doi.org/10.3892/ol.2017.5783
MLA
Panelli Santos, K. C., Matsuzaki, H., Unetsubo, T., Tsuyoshi, S., Nagatsuka, H., Asaumi, J."De novo myoepithelial carcinoma with multiple metastases arising from a submandibular salivary gland: A case report". Oncology Letters 13.4 (2017): 2679-2683.
Chicago
Panelli Santos, K. C., Matsuzaki, H., Unetsubo, T., Tsuyoshi, S., Nagatsuka, H., Asaumi, J."De novo myoepithelial carcinoma with multiple metastases arising from a submandibular salivary gland: A case report". Oncology Letters 13, no. 4 (2017): 2679-2683. https://doi.org/10.3892/ol.2017.5783
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