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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2017 Volume 13 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

What is known about melatonin, chemotherapy and altered gene expression in breast cancer (Review)

Carlos Martínez‑Campa, Javier Menéndez‑Menéndez, Carolina Alonso‑González, Alicia González, Virginia Álvarez‑García, Samuel Cos
Pages: 2003-2014
Published online on: 10 February 2017

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Review Open Access

Harnessing antitumor immunity: Employment of tumor recall antigens to optimize the inflammatory response to cancer (Review)

Kimberly A. Silverio, Shyam A. Patel
Pages: 2015-2020
Published online on: 13 February 2017

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Review

Expression, regulation and function of miR-495 in healthy and tumor tissues (Review)

Hongli Chen, Xiaman Wang, Ju Bai, Aili He
Pages: 2021-2026
Published online on: 13 February 2017

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Review

Prognostic relevance of DNA flow cytometry in breast cancer revisited: The 25‑year experience of the Portuguese Institute of Oncology of Lisbon (Review)

António E. Pinto, Teresa Pereira, Giovani L. Silva, Saudade André
Pages: 2027-2033
Published online on: 13 February 2017

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Article

Modeling nasopharyngeal carcinoma in three dimensions (Review)

Prabu Siva Sankar, Mohd Firdaus Che Mat, Kalaivani Muniandy, Benedict Lian Shi Xiang, Phang Su Ling, Susan Ling Ling Hoe, Alan Soo‑Beng Khoo, Nethia Mohana‑Kumaran
Pages: 2034-2044
Published online on: 08 February 2017

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Article Open Access

Location of NLS-RARα protein in NB4 cell and nude mice

Hui Wang, Rong Yang, Liang Zhong, Xin‑Yu Zhu, Peng‑Peng Ma, Xiao‑Qun Yang, Kai‑Ling Jiang, Bei‑Zhong Liu
Pages: 2045-2052
Published online on: 08 February 2017

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Article Open Access

MicroRNA-30e-3p inhibits cell invasion and migration in clear cell renal cell carcinoma by targeting Snail1

Daya Wang, Chao Zhu, Yifan Zhang, Yuenan Zheng, Feiju Ma, Li Su, Guojian Shao
Pages: 2053-2058
Published online on: 07 February 2017

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Article Open Access

Growth of tyrosine kinase inhibitor-resistant Philadelphia-positive acute lymphoblastic leukemia: Role of bone marrow stromal cells

Cheng Zhang, Xi Zhang, Shi‑Jie Yang, Xing‑Hua Chen
Pages: 2059-2070
Published online on: 07 February 2017

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Article Open Access

MicroRNA-124 regulates the radiosensitivity of non-small cell lung cancer cells by targeting TXNRD1

Chuncheng Hao, Xiangying Xu, Jia Ma, Jun Xia, Bingbing Dai, Lili Liu, Yuyan Ma
Pages: 2071-2078
Published online on: 08 February 2017

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Article Open Access

Personalized therapy tests for the monitoring of chronic lymphocytic leukemia development

Małgorzata Rogalińska, Paweł Góralski, Jerzy Z. Błoński, Paweł Robak, Jan Barciszewski, Aneta Koceva‑Chyła, Henryk Piekarski, Tadeusz Robak, Zofia M. Kilianska
Pages: 2079-2084
Published online on: 13 February 2017

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Case Report Open Access

Downregulation of EGFR in a metastatic brain lesion of EGFR-mutated non-small cell lung cancer using a tyrosine kinase inhibitor: A case report

Masatoshi Takagaki, Manabu Kinoshita, Kazumi Nishino, Masakazu Nakano, Hiroko Adachi, Morio Ueno, Masanori Kitamura, Yasunori Fujimoto, Kei Tashiro, Yasuhiko Tomita, Fumio Imamura, Toshiki Yoshimine
Pages: 2085-2088
Published online on: 06 February 2017

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Article Open Access

Gene signatures associated with drug resistance to irinotecan and oxaliplatin predict a poor prognosis in patients with colorectal cancer

Xinrong Sun, Xiang Wang, Wenming Feng, Huihui Guo, Chengwu Tang, Yongliang Lu, Xiaobin Xiang, Ying Bao
Pages: 2089-2096
Published online on: 07 February 2017

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Article Open Access

Matrix metalloproteinases in Vietnamese patients with colorectal cancer

Thao Phuong Bui, Anh Ngoc Hoang, Phuong Lan Le, Bich Thi Pham, Linh Thi Tu Nguyen, Ha Minh Do, To Van Ta, Thai Hong Trinh
Pages: 2097-2104
Published online on: 06 February 2017

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Case Report Open Access

Anti-osteoclastic agent, denosumab, for a giant cell tumor of the bone with concurrent Paget's disease: A case report

Takaaki Tanaka, John Slavin, Sue‑Anne McLachlan, Peter Choong
Pages: 2105-2108
Published online on: 08 February 2017

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Article Open Access

Overexpression of erythropoietin-producing hepatocyte receptor B4 and ephrin-B2 is associated with estrogen receptor expression in endometrial adenocarcinoma

Ling‑Dan Dong, Xiang‑Lin Cheng, Long Zhou, Qing Huang, Jun‑Chuan Li, Cun‑Jian Yi
Pages: 2109-2114
Published online on: 08 February 2017

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Article Open Access

Methylation of CDKN2B CpG islands is associated with upregulated telomerase activity in children with acute lymphoblastic leukemia

Qian Hu, Xiaowen Chen, Sixi Liu, Ruiqi Wen, Xiuli Yuan, Dandan Xu, Guosheng Liu, Feiqiu Wen
Pages: 2115-2120
Published online on: 09 February 2017

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Article Open Access

Synergistic effects of a novel lipid-soluble extract from Pinellia pedatisecta Schott and cisplatin on human cervical carcinoma cell lines through the regulation of DNA damage response signaling pathway

Mingxing Zhang, Hongwei Zhang, Yi Yu, Haixia Huang, Guiling Li, Congjian Xu
Pages: 2121-2128
Published online on: 14 February 2017

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Case Report Open Access

Distinguishing between intramural pregnancy and choriocarcinoma: A case report

Shan Su, Devendra Chavan, Kun Song, Dennis Chi, Guiyu Zhang, Xiaohui Deng, Li Li, Beihua Kong
Pages: 2129-2132
Published online on: 14 February 2017

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Article Open Access

Inhibition of CYFIP2 promotes gastric cancer cell proliferation and chemoresistance to 5‑fluorouracil through activation of the Akt signaling pathway

Shuhua Jiao, Nuo Li, Shuang Cai, Haimei Guo, Yanhui Wen
Pages: 2133-2140
Published online on: 14 February 2017

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Article Open Access

Arsenic trioxide inhibits tumor-induced myeloid-derived suppressor cells and enhances T-cell activity

Qingmin Gao, Jingwei Jiang, Zhaohui Chu, Hao Lin, Xinli Zhou, Xiaohua Liang
Pages: 2141-2150
Published online on: 06 February 2017

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Article Open Access

A comprehensive analysis of cancer-driving mutations and genes in kidney cancer

Chengmei Long, Jinbo Jian, Xinchang Li, Gongxian Wang, Jingen Wang
Pages: 2151-2160
Published online on: 07 February 2017

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Article Open Access

Expression and function of MutT homolog 1 in distinct subtypes of breast cancer

Xiaohui Zhang, Wei Song, Yidong Zhou, Feng Mao, Yan Lin, Jinghong Guan, Qiang Sun
Pages: 2161-2168
Published online on: 13 February 2017

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Article Open Access

Frequent expression of human leukocyte antigen class I and the status of intratumoral immune cells in alveolar soft part sarcoma

Akira Ogose, Hiroyuki Kawashima, Tetsuo Hotta, Takashi Ariizumi, Tetsuro Yamagishi, Naoki Oike, Taro Sasaki, Hiroshi Hatano, Hajime Umezu, Naoto Endo
Pages: 2169-2176
Published online on: 08 February 2017

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Article Open Access

Prognostic value of intratumoral carbonic anhydrase IX expression in testicular germ cell tumors

Katarina Kalavska, Zuzana Cierna, Michal Chovanec, Martina Takacova, Daniela Svetlovska, Viera Miskovska, Jana Obertova, Patrik Palacka, Jan Rajec, Zuzana Sycova‑Mila, Katarina Machalekova, Karol Kajo, Stanislav Spanik, Jozef Mardiak, Pavel Babal, Silvia Pastorekova, Michal Mego
Pages: 2177-2185
Published online on: 14 February 2017

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Article Open Access

Characterization of single lesion nonfunctioning pancreatic neuroendocrine carcinoma via computed tomography

Jibo Hu, Qunhui Hu, Hongjie Hu
Pages: 2186-2190
Published online on: 13 February 2017

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Article Open Access

miR-150 is downregulated in osteosarcoma and suppresses cell proliferation, migration and invasion by targeting ROCK1 Retraction in /10.3892/ol.2022.13462

Chang‑Hui Li, Teng‑Bo Yu, Hong‑Wei Qiu, Xia Zhao, Chuan‑Li Zhou, Chao Qi
Pages: 2191-2197
Published online on: 09 February 2017

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Article Open Access

Optimized construction of MUC1-VNTRn DNA vaccine and its anti-pancreatic cancer efficacy

Yuan‑Feng Gong, Quan‑Bo Zhou, Ya‑Di Liao, Cong Mai, Tie‑Jun Chen, Yun‑Qiang Tang, Ru‑Fu Chen
Pages: 2198-2206
Published online on: 13 February 2017

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Article Open Access

Increased B7-H4 expression during esophageal squamous cell carcinogenesis is associated with IL-6/STAT3 signaling pathway activation in mice

Xinran Chen, Wei Wang, Hongwei Man, Pengfei Li, Baoen Shan
Pages: 2207-2215
Published online on: 07 February 2017

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Article Open Access

FAM53B truncation caused by t(10;19)(q26;q13) chromosome translocation in acute lymphoblastic leukemia

Ioannis Panagopoulos, Ludmila Gorunova, Synne Torkildsen, Anne Tierens, Sverre Heim, Francesca Micci
Pages: 2216-2220
Published online on: 08 February 2017

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Article Open Access

New applications of the acridine orange fluorescence staining method: Screening for circulating tumor cells

Min Liu, Ruizhe Li, Yang Tang, Jiwu Chang, Rong Han, Shumin Zhang, Ning Jiang, Fuling Ma
Pages: 2221-2229
Published online on: 13 February 2017

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Article Open Access

Neuroendocrine differentiation is predictive of poor survival in patients with stage II colorectal cancer

Yue Liu, Jinjie He, Jinghong Xu, Jun Li, Yurong Jiao, Dikai Bei, Yeting Hu, Haiyan Chen, Qian Xiao, Kefeng Ding
Pages: 2230-2236
Published online on: 07 February 2017

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Article Open Access

Decreased calpain 6 expression is associated with tumorigenesis and poor prognosis in HNSCC

Yinzhou Xiang, Fen Li, Lei Wang, Anyuan Zheng, Jingjing Zuo, Man Li, Yongping Wang, Yong Xu, Chen Chen, Shiming Chen, Bokui Xiao, Zezhang Tao
Pages: 2237-2243
Published online on: 07 February 2017

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Article Open Access

Association between Wnt inhibitory factor 1 and receptor tyrosine kinase-like orphan receptor 2 protein expression and the clinical pathological significance in benign and malignant pancreatic lesions

Daoqi Zhu, Zhulin Yang, Ziru Liu, Qiong Zou, Yuan Yuan, Chunhong Hu
Pages: 2244-2252
Published online on: 08 February 2017

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Article Open Access

CXCR4 knockdown inhibits the growth and invasion of nasopharyngeal cancer stem cells

Yuan Tian, Yan Song, Weiliang Bai, Xiulan Ma, Zhong Ren
Pages: 2253-2259
Published online on: 08 February 2017

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Article Open Access

Notch signaling is important for epithelial-mesenchymal transition induced by low concentrations of doxorubicin in osteosarcoma cell lines

Jian Yang, Weichun Guo, Lu Wang, Ling Yu, Hongjun Mei, Shuo Fang, Anyuan Chen, Yang Liu, Kezhou Xia, Gaiwei Liu
Pages: 2260-2268
Published online on: 09 February 2017

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Article

Expression of novel cancer/testis antigen TMEM31 increases during metastatic melanoma progression

Jiaqiang Li, Xiaowen Zou, Cailing Li, Jianhua Zhong, Yan Chen, Xiaoyue Zhang, Fuming Qi, Mengshuo Li, Zhiming Cai, Aifa Tang
Pages: 2269-2273
Published online on: 13 February 2017

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Article Open Access

Upregulation of KIN17 is associated with non-small cell lung cancer invasiveness

Yuzhao Zhang, Senlin Huang, Hongyi Gao, Kunhe Wu, Xiaoming Ouyang, Zheng Zhu, Xiaobin Yu, Tao Zeng
Pages: 2274-2280
Published online on: 09 February 2017

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Article Open Access

KLF7 overexpression in human oral squamous cell carcinoma promotes migration and epithelial-mesenchymal transition

Xiaojun Ding, Xinhao Wang, Yiming Gong, Hong Ruan, Yang Sun, Youcheng Yu
Pages: 2281-2289
Published online on: 13 February 2017

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Article Open Access

Diagnosing and discriminating between primary and secondary aneurysmal bone cysts

Hiromi Sasaki, Satoshi Nagano, Hirofumi Shimada, Masahiro Yokouchi, Takao Setoguchi, Yasuhiro Ishidou, Osamu Kunigou, Kosuke Maehara, Setsuro Komiya
Pages: 2290-2296
Published online on: 07 February 2017

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Article Open Access

Variation and significance of secretory immunoglobulin A, interleukin 6 and dendritic cells in oral cancer

Suxin Zhang, Xin Zhang, Ke Yin, Tianke Li, Yang Bao, Zhong Chen
Pages: 2297-2303
Published online on: 08 February 2017

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Article Open Access

Notch1 targeted regulation of mir-224/LRIG2 signaling for the proliferation and apoptosis of cervical cancer cells

Lanxiang Cong, Fang Zhang, Huaihai Shang
Pages: 2304-2308
Published online on: 03 February 2017

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Article Open Access

Treatment with the herbal formula Songyou Yin inhibits epithelial-mesenchymal transition in hepatocellular carcinoma through downregulation of TGF-β1 expression and inhibition of the SMAD2/3 signaling pathway

Susu Zheng, Qingan Jia, Hujia Shen, Xin Xu, Jiajia Ling, Chuyu Jing, Boheng Zhang
Pages: 2309-2315
Published online on: 08 February 2017

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Article Open Access

Sphingosine kinase 1: A novel independent prognosis biomarker in hepatocellular carcinoma

Huajie Cai, Xuemeng Xie, Ling Ji, Xiaojiao Ruan, Zhihai Zheng
Pages: 2316-2322
Published online on: 13 February 2017

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Article Open Access

Immunological effects of vaccines combined with granulocyte colony-stimulating factor on a murine WEHI-3 leukemia model

Jinqiu Chen, Miling Zhang, Fuling Zhou, Jin Wang, Ben Niu, Wanggang Zhang
Pages: 2323-2329
Published online on: 13 February 2017

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Article Open Access

Inhibition of lung cancer growth by HangAmDan-B is mediated by macrophage activation to M1 subtype

Hye‑Rin Park, Eun‑Ji Lee, Seong‑Cheol Moon, Tae‑Wook Chung, Keuk‑Jun Kim, Hwa‑Seung Yoo, Chong‑Kwan Cho, Ki‑Tae Ha
Pages: 2330-2336
Published online on: 13 February 2017

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Article Open Access

Stevioside induced cytotoxicity in colon cancer cells via reactive oxygen species and mitogen-activated protein kinase signaling pathways-mediated apoptosis

Hai‑Peng Ren, Xiao‑Yan Yin, Hai‑Ying Yu, Hai‑Feng Xiao
Pages: 2337-2343
Published online on: 14 February 2017

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Article Open Access

Safety and effectiveness of localized lung resection combined with neoadjuvant chemotherapy in the treatment of stage I-II non-small cell lung cancer

Bing Zhu, Jianru Yang, Pei Zhang, Lin Shen, Xiaolong Li, Jing Li
Pages: 2344-2348
Published online on: 03 February 2017

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Article Open Access

miR-215 suppresses proliferation and migration of non-small cell lung cancer cells

Xiaopan Cai, Dongyu Peng, Haifeng Wei, Xinghai Yang, Quan Huang, Zaijun Lin, Wei Xu, Ming Qian, Cheng Yang, Tielong Liu, Wangjun Yan, Jian Zhao
Pages: 2349-2353
Published online on: 07 February 2017

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Article Open Access

miR-22 promotes apoptosis of osteosarcoma cells via inducing cell cycle arrest

Pengzhou Gai, Hongliang Sun, Guangda Wang, Qiang Xu, Xiaojun Qi, Zuofu Zhang, Lei Jiang
Pages: 2354-2358
Published online on: 02 February 2017

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Article

Correlation between epidermal growth factor receptor mutations and the expression of estrogen receptor-β in advanced non-small cell lung cancer

Fang Deng, Ming Li, Wu‑Lin Shan, Li‑Ting Qian, Shui‑Ping Meng, Xiao‑Lei Zhang, Bao‑Long Wang
Pages: 2359-2365
Published online on: 10 February 2017

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Article

Expression of B-cell translocation gene 2 is associated with favorable prognosis in hepatocellular carcinoma patients and sensitizes irradiation-induced hepatocellular carcinoma cell apoptosis in vitro and in nude mice

Yuanyuan Chen, Chuan Chen, Zhimin Zhang, He Xiao, Bijing Mao, Huan Huang, Chenchen Ding, Lin Lei, Hui Zhang, Jian Li, Mei Jiang, Ge Wang
Pages: 2366-2372
Published online on: 07 February 2017

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Case Report

Carcinoid syndrome from a carcinoid tumor of the pancreas without liver metastases: A case report and literature review

Nikolaos Zavras, Demetrios Schizas, Nikolaos Machairas, Vasileia Damaskou, Nikolaos Economopoulos, Anastasios Machairas
Pages: 2373-2376
Published online on: 06 February 2017

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Article

Downregulation of NPM expression by Her-2 reduces resistance of gastric cancer to oxaliplatin

Zhenni Sun, Lu Yue, Zan Shen, Yong Li, Aihua Sui, Tianjun Li, Qian Tang, Ruyong Yao, Yongning Sun
Pages: 2377-2384
Published online on: 13 February 2017

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Article

Astrocyte elevated gene-1 promotes the proliferation and invasion of breast cancer cells by activating the Wnt/β‑catenin signaling pathway

Mengxi Li, Yuna Dai, Li Wang, Lei Li
Pages: 2385-2390
Published online on: 08 February 2017

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Article

Expression of IMP3 as a marker for predicting poor outcome in gastroenteropancreatic neuroendocrine neoplasms

Li‑Mian Er, Yong Li, Ming‑Li Wu, Qun Zhao, Bi‑Bo Tan, Xiao‑Ling Wang, Shi‑Jie Wang
Pages: 2391-2396
Published online on: 14 February 2017

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Article Open Access

Zerumbone inhibits melanoma cell proliferation and migration by altering mitochondrial functions

Hua Yan, Ming‑Yuan Ren, Zheng‑Xiang Wang, Shi‑Jun Feng, Si Li, Yi Cheng, Cai‑Xia Hu, Shun‑Qiang Gao, Guo‑Qiang Zhang
Pages: 2397-2402
Published online on: 14 February 2017

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Article

Identification of microRNA-615-3p as a novel tumor suppressor in non-small cell lung cancer

Heng‑Ying Pu, Rui Xu, Mei‑Yin Zhang, Lin‑Jing Yuan, Jing‑Ye Hu, Guo‑Liang Huang, Hui‑Yun Wang
Pages: 2403-2410
Published online on: 07 February 2017

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Article

Comparison of the seleno-transcriptome expression between human non-cancerous mammary epithelial cells and two human breast cancer cell lines

Fabiola Rusolo, Francesca Capone, Raffaella Pasquale, Antonella Angiolillo, Giovanni Colonna, Giuseppe Castello, Maria Costantini, Susan Costantini
Pages: 2411-2417
Published online on: 13 February 2017

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Article

Na7CrCuW11O39.16H2O induces apoptosis in human ovarian cancer SKOV3 cells through the p38 signaling pathway

Hai‑Ying Liu, Xiu‑Li Pan, Jia‑Nan Tian, Hui Sun, Qing Huan, Yu‑Ling Huang, Jian‑Qiao Liu
Pages: 2418-2424
Published online on: 13 February 2017

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Article

Analysis of EGFR mutation status in tissue and plasma for predicting response to EGFR‑TKIs in advanced non‑small‑cell lung cancer

Yuyan Wang, Jianchun Duan, Hanxiao Chen, Hua Bai, Tongtong An, Jun Zhao, Zhijie Wang, Minglei Zhuo, Shuhang Wang, Jie Wang
Pages: 2425-2431
Published online on: 14 February 2017

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Article

STAT3 activation and risk of recurrence in meningiomas

Mahlon Johnson, Mary O'Connell, Kevin Walter
Pages: 2432-2436
Published online on: 14 February 2017

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Survivin DEx3 as a biomarker of thyroid cancers: A study at the mRNA and protein level

Joanna Waligórska‑Stachura, Nadia Sawicka‑Gutaj, Maciej Zabel, Mirosław Andrusiewicz, Paweł Gut, Agata Czarnywojtek, Marek Ruchała
Pages: 2437-2441
Published online on: 10 February 2017

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miR-185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma Corrigendum in /10.3892/ol.2026.15480

Jinpeng He, Ning Tian, Yanli Yang, Liangliang Jin, Xiu Feng, Junrui Hua, Sulan Lin, Bing Wang, He Li, Jufang Wang
Pages: 2442-2448
Published online on: 08 February 2017

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Review

Epigenetic silencing of protocadherin 10 in colorectal cancer (Review)

Xian Zhong, Hong Shen, Jianshan Mao, Jiawei Zhang, Weidong Han
Pages: 2449-2453
Published online on: 13 February 2017

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Neutrophil‑lymphocyte ratio predicts survival in pancreatic neuroendocrine tumors

Guopei Luo, Chen Liu, He Cheng, Kaizhou Jin, Meng Guo, Yu Lu, Jiang Long, Jin Xu, Quanxing Ni, Jie Chen, Xianjun Yu
Pages: 2454-2458
Published online on: 13 February 2017

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Study of the expression and function of ACY1 in patients with colorectal cancer

Bing Yu, Xuezhong Liu, Xiuzhen Cao, Mingyue Zhang, Hong Chang
Pages: 2459-2464
Published online on: 08 February 2017

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Notch is a critical regulator in cervical cancer by regulating Numb splicing

Cai Rong, Yu Feng, Zhou Ye
Pages: 2465-2470
Published online on: 07 February 2017

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The role of MRP1 in the multidrug resistance of colorectal cancer

Dongxing Cao, Shaolan Qin, Yifei Mu, Ming Zhong
Pages: 2471-2476
Published online on: 14 February 2017

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The nutritional herb Epimedium grandiflorum inhibits the growth in a model for the Luminal A molecular subtype of breast cancer

Nitin T. Telang, Gou Li, Meena Katdare, Daniel W. Sepkovic, H. Leon Bradlow, George Y.C. Wong
Pages: 2477-2482
Published online on: 13 February 2017

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Association between polymorphisms in TP53 and MDM2 genes and susceptibility to prostate cancer

Mohammad Hashemi, Shadi Amininia, Mahboubeh Ebrahimi, Nasser Simforoosh, Abbas Basiri, Seyed Amir Mohsen Ziaee, Behzad Narouie, Mehdi Sotoudeh, Mohammad Javad Mollakouchekian, Esmaeil Rezghi Maleki, Hamideh Hanafi‑Bojd, Maryam Rezaei, Gholamreza Bahari, Mohsen Taheri, Saeid Ghavami
Pages: 2483-2489
Published online on: 14 February 2017

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Whole‑body low‑dose computed tomography in multiple myeloma staging: Superior diagnostic performance in the detection of bone lesions, vertebral compression fractures, rib fractures and extraskeletal findings compared to radiography with similar radiation exposure

Lukas Lambert, Petr Ourednicek, Zuzana Meckova, Giampaolo Gavelli, Jan Straub, Ivan Spicka
Pages: 2490-2494
Published online on: 13 February 2017

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Prevalence of human papillomavirus infection of the anal canal in women: A prospective analysis of high-risk populations

Bernd P. Kost, Jörg Hofmann, Susanne Stoellnberger, Florian Bergauer, Thomas Blankenstein, Irene Alba‑Alejandre, Angela Stein, Claudia Stuckart, Katharina Weizsäcker, Ioannis Mylonas, Sven Mahner, Andrea Gingelmaier
Pages: 2495-2501
Published online on: 10 February 2017

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Review

Chemoresistance in pancreatic cancer: Emerging concepts (Review)

Manu Gnanamony, Christopher S. Gondi
Pages: 2507-2513
Published online on: 24 February 2017

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Review

The regulation of proteins associated with the cytoskeleton by hepatitis B virus X protein during hepatocarcinogenesis (Review)

Fanyun Kong, Hongjuan You, Renxian Tang, Kuiyang Zheng
Pages: 2514-2520
Published online on: 22 February 2017

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Polyphenolic compounds from Korean Lonicera japonica Thunb. induces apoptosis via AKT and caspase cascade activation in A549 cells

Kwang Il Park, Hyeonsoo Park, Arulkumar Nagappan, Gyeong Eun Hong, Silvia Yumnam, Ho Jeong Lee, Eun Hee Kim, Won Sup Lee, Sung Chul Shin, Jin A Kim, Sang Joon Lee, Jin Yeul Ma, Taesun Min, Jeong Doo Heo, Gon Sup Kim
Pages: 2521-2530
Published online on: 23 February 2017

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WT1-associated protein is a novel prognostic factor in pancreatic ductal adenocarcinoma

Bing‑Qi Li, Shuai Huang, Qian‑Qian Shao, Jian Sun, Li Zhou, Lei You, Tai‑Ping Zhang, Quan Liao, Jun‑Chao Guo, Yu‑Pei Zhao
Pages: 2531-2538
Published online on: 28 February 2017

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Cytokeratin 17 and Ki-67: Immunohistochemical markers for the differential diagnosis of keratoacanthoma and squamous cell carcinoma

Cem Leblebici, Esra Pasaoglu, Canan Kelten, Seher Darakci, Nevra Dursun
Pages: 2539-2548
Published online on: 01 March 2017

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Prognostic and predictive role of COX-2, XRCC1 and RASSF1 expression in patients with esophageal squamous cell carcinoma receiving radiotherapy

Yaowen Zhang, Shangwen Dong, Ruiping Xu, Yanping Yang, Zhiyong Zheng, Xiaojing Wang, Runchuan Ren, Ronggang Sun, Ming Li, Haijun Yang, Yuting Huang, Fuyou Zhou, Anping Zheng
Pages: 2549-2556
Published online on: 24 February 2017

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Deregulation of miR‑193b affects the growth of colon cancer cells via transforming growth factor‑β and regulation of the SMAD3 pathway

Kaiming Wu, Zhenxian Zhao, Jun Ma, Jianhui Chen, Jianjun Peng, Shibin Yang, Yulong He
Pages: 2557-2562
Published online on: 22 February 2017

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F10, a novel hydatidiform mole-associated gene, inhibits the paclitaxel sensitivity of A549 lung cancer cells by downregulating BAX and caspase-3

Yali Song, Wei Cao, Xi Zhu, Zhuolin Qiu, Xiaoping Yang, Jing Liu, Ruoting Xu, Weizhuang Yuan, Song Quan
Pages: 2563-2568
Published online on: 20 February 2017

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15-Deoxy-Δ12,14-prostaglandin J2 inhibits migration of human thyroid carcinoma cells by disrupting focal adhesion complex and adherens junction

Ya‑Chieh Wu, Yun‑Ting Jhao, Yu‑Chen Cheng, Ying Chen
Pages: 2569-2576
Published online on: 23 February 2017

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SATB1 promotes epithelial‑mesenchymal transition and metastasis in prostate cancer

Honggang Qi, Xinyang Fu, Yeping Li, Xiang Pang, Sansan Chen, Xiaojun Zhu, Fei Li, Wanlong Tan
Pages: 2577-2582
Published online on: 22 February 2017

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Polycomb group expression signatures in the malignant progression of gliomas

Qi Hu, Weining Wu, Ailiang Zeng, Tianfu Yu, Feng Shen, Er Nie, Yingyi Wang, Ning Liu, Junxia Zhang, Yongping You
Pages: 2583-2590
Published online on: 20 February 2017

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CHK2 is involved in the p53-independent radiosensitizing effects of valproic acid

Dong Wan Choo, Sung Ho Goh, Young Woo Cho, Hye Jung Baek, Eun Jung Park, Noboru Motoyama, Tae Hyun Kim, Joo Young Kim, Sang Soo Kim
Pages: 2591-2598
Published online on: 01 March 2017

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Oct4 induces EMT through LEF1/β-catenin dependent WNT signaling pathway in hepatocellular carcinoma

Lu Sun, Tianhua Liu, Shu Zhang, Kun Guo, Yinkun Liu
Pages: 2599-2606
Published online on: 28 February 2017

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FFJ‑3 inhibits PKM2 protein expression via the PI3K/Akt signaling pathway and activates the mitochondrial apoptosis signaling pathway in human cancer cells

Dengyun Li, Xiaoli Wei, Mingming Ma, Huina Jia, Yu Zhang, Wenyi Kang, Tianxiao Wang, Xiaoyan Shi
Pages: 2607-2614
Published online on: 22 February 2017

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MicroRNA‑130b promotes cell migration and invasion by inhibiting peroxisome proliferator‑activated receptor‑γ in human glioma

Peidong Li, Xinjun Wang, Qiao Shan, Yuehui Wu, Zhen Wang
Pages: 2615-2622
Published online on: 22 February 2017

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Identification of target genes of cediranib in alveolar soft part sarcoma using a gene microarray

Wenhua Jiang, Pengfei Liu, Xiaodong Li, Ping Wang
Pages: 2623-2630
Published online on: 24 February 2017

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miR-185-3p regulates the invasion and metastasis of nasopharyngeal carcinoma by targeting WNT2B in vitro

Chao Liu, Guo Li, Shuling Ren, Zhongwu Su, Yunyun Wang, Yongquan Tian, Yong Liu, Yuanzheng Qiu
Pages: 2631-2636
Published online on: 24 February 2017

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Case Report Open Access

Anterior mediastinum invasion by multiple myeloma: A case report

Ying‑Hui Xu, Lu‑Guo Sun, Chao Sun, Ou Bai, Ting‑Ting Liang, Ke‑Wei Ma
Pages: 2637-2641
Published online on: 22 February 2017

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Role of reactive oxygen species in the anticancer activity of botanicals: Comparing sensitivity profiles

Zoya Cohen, Yair Maimon, Noah Samuels, Raanan Berger
Pages: 2642-2648
Published online on: 17 February 2017

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Lentivirus-mediated RNA interference of tripartite motif 68 inhibits the proliferation of colorectal cancer cell lines SW1116 and HCT116 in vitro

Zhen Tan, Xiaoshuang Liu, Enda Yu, Hantao Wang, Lijun Tang, Hao Wang, Chuangang Fu
Pages: 2649-2655
Published online on: 28 February 2017

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Inhibitory effect and mechanism of exogenous mammalian sterile 20-like kinase 1 on the growth of human colorectal cancer

Jian Wu, Xiaohong Yang, Hongfei Lu, Liqiao Liu, Baohua Xu, Shuangyan Zheng, Bo Yu, Kemin Jie, Fusheng Wan
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Published online on: 28 February 2017

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GNAQ mutation R183Q as a potential cause of familial Sturge-Weber syndrome: A case report

Zhengyi Huang, Yuchi Li, Zengxia Zhao, Jun Hu, Xiaoxin Tong, Xuhui Chen, Shuyun Liu, Xiaonan Xu, Yongjun Tao, Tingting Wang, Xin Cheng, Yangyang Dai, Yaoting Gui, Jun Wu
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Published online on: 01 March 2017

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Bioinformatics analysis of the prognostic value of Tripartite Motif 28 in breast cancer

Ling Hao, Jun Leng, Ruijing Xiao, Tembo Kingsley, Xinran Li, Zhenbo Tu, Xiangyong Yang, Xinzhou Deng, Meng Xiong, Jie Xiong, Qiuping Zhang
Pages: 2670-2678
Published online on: 22 February 2017

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De novo myoepithelial carcinoma with multiple metastases arising from a submandibular salivary gland: A case report

Karina Cecília Panelli Santos, Hidenobu Matsuzaki, Teruhisa Unetsubo, Shimo Tsuyoshi, Hitoshi Nagatsuka, Jun‑Ichi Asaumi
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Published online on: 28 February 2017

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Expression of GLP-1 receptor and CD26 in human thyroid C-cells: The association of thyroid C-cell tumorigenesis with incretin-based medicine

Yuejia Song, Min Zhou, Yang Cao, Jiping Qi, Jingshu Geng, Xiaomin Liu
Pages: 2684-2690
Published online on: 20 February 2017

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Flow cytometry‑based immunophenotypic analysis of primary systemic light chain amyloidosis

Xiangwen Diao, Juan Li, Juan Ouyang, Junru Liu, Beihui Huang, Meilan Chen, Jingli Gu
Pages: 2691-2697
Published online on: 22 February 2017

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Targeting assay of a fusion protein applied in enzyme prodrug therapy

Hao Wang, Jin‑Jian Liu, Xiao‑Liang Zhou
Pages: 2698-2702
Published online on: 22 February 2017

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Chemotherapy regimen based on sorafenib combined with 5-FU on HIF-1α and VEGF expression and survival in advanced gastric cancer patients

Ronghui Cheng, Hongmei Yong, Yunhong Xia, Qingsong Xie, Guangyi Gao, Xueyi Zhou
Pages: 2703-2707
Published online on: 23 February 2017

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Case Report Open Access

Brainstem tuberculous abscesses successfully treated by microsurgical excision: A case report and review of the literature

Baofeng Xu, Yandong Zhang, Jinlu Yu
Pages: 2708-2712
Published online on: 28 February 2017

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Pulmonary artery intimal sarcoma misdiagnosed as pulmonary embolism: A case report

Shuyan Jiang, Jiaxin Li, Qingshi Zeng, Jiexian Liang
Pages: 2713-2716
Published online on: 24 February 2017

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Detection of circulating tumor cells in patients with non-small cell lung cancer using a size-based platform

Chung‑Hee Sonn, Jong Ho Cho, Jae‑Won Kim, Moon Sung Kang, Jinseon Lee, Jhingook Kim
Pages: 2717-2722
Published online on: 23 February 2017

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Survivin downregulation using siRNA nanoliposomes inhibits cell proliferation and promotes the apoptosis of MHCC-97H hepatic cancer cells: An in vitro and in vivo study

Ziqin Liu, Tianyou Wang, Zhaoxia Zhang, Suoqin Tang, Shunqiao Feng, Mei Yue, Mengze Hu, Litian Xuan, Yanfei Chen
Pages: 2723-2730
Published online on: 21 February 2017

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Expression of CXCL12 and its receptor CXCR4 in patients with adenomyosis

Juan Li, Geping Yin, Ming Chen, Shujun Yang, Aifang Wu, Jing Liang, Zheng Yuan
Pages: 2731-2736
Published online on: 22 February 2017

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Melatonin treatment induces apoptosis through regulating the nuclear factor-κB and mitogen-activated protein kinase signaling pathways in human gastric cancer SGC7901 cells

Weimin Li, Zhonglue Wang, Yina Chen, Kaijing Wang, Ting Lu, Fei Ying, Mengdi Fan, Zhiyin Li, Jiansheng Wu
Pages: 2737-2744
Published online on: 28 February 2017

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Prognostic value of MLH1 promoter methylation in male patients with esophageal squamous cell carcinoma

Dongping Wu, Xiaoying Chen, Yan Xu, Haiyong Wang, Guangmao Yu, Luping Jiang, Qingxiao Hong, Shiwei Duan
Pages: 2745-2750
Published online on: 22 February 2017

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Effects of irradiation on radioresistance, HOTAIR and epithelial‑mesenchymal transition/cancer stem cell marker expression in esophageal squamous cell carcinoma

Chunli Da, Li Wu, Yuting Liu, Ruozheng Wang, Ruiguang Li
Pages: 2751-2757
Published online on: 23 February 2017

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Reduced EBP50 expression levels are correlated with unfavorable clinicopathological features of extrahepatic bile duct carcinoma and promote the proliferation and migration of QBC939 cells

Duiping Feng, Ying Xiong, Zhiqiang Peng, Qiang Ma, Tao Tao, Hua Liu, Jianfang Liang, Zhigang Wei, Junfang Zheng, Lei Wang, Hui Zhang
Pages: 2758-2764
Published online on: 28 February 2017

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Case Report

Metastasis from a primary hepatic angiosarcoma to the colon: A case report and literature review

Yukako Mokutani, Taishi Hata, Yuichiro Miyake, Hideki Kuroda, Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Tsunekazu Mizushima, Hirofumi Yamamoto, Yuichiro Doki, Masaki Mori
Pages: 2765-2769
Published online on: 21 February 2017

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Microarray based analysis of gene regulation by mesenchymal stem cells in breast cancer

Ming Zhang, Chang E. Gao, Wen Hui Li, Yi Yang, Li Chang, Jian Dong, Yan Xin Ren, De Dian Chen
Pages: 2770-2776
Published online on: 24 February 2017

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Identification of molecular characteristics induced by radiotherapy in rectal cancer based on microarray data

Chang Ge, Mengxia Wu, Guifang Chen, Guanying Yu, Dehui Ji, Shaozhao Wang
Pages: 2777-2783
Published online on: 20 February 2017

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Investigation of differentially‑expressed microRNAs and genes in cervical cancer using an integrated bioinformatics analysis

Zhanzhan Xu, Yu Zhou, Fang Shi, Yexuan Cao, Thi Lan Anh Dinh, Jing Wan, Min Zhao
Pages: 2784-2790
Published online on: 22 February 2017

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Ethanolic extract of Thevetia peruviana flowers enhances TNF-α and TRAIL-induced apoptosis of human cervical cancer cells via intrinsic and extrinsic pathways

Chittima Managit, Hiroaki Sakurai, Ikuo Saiki
Pages: 2791-2798
Published online on: 17 February 2017

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Regulation of cytotoxicity and apoptosis-associated pathways contributes to the enhancement of efficacy of cisplatin by baicalein adjuvant in human A549 lung cancer cells

Suparata Kiartivich, Ying Wei, Jiaqi Liu, Rungtip Soiampornkul, Mihui Li, Hongying Zhang, Jingcheng Dong
Pages: 2799-2804
Published online on: 16 February 2017

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Terrein performs antitumor functions on esophageal cancer cells by inhibiting cell proliferation and synergistic interaction with cisplatin

Yanqing Wu, Yinghua Zhu, Shunrong Li, Minhua Zeng, Junjun Chu, Pengnan Hu, Jingjing Li, Qiannan Guo, Xiao‑Bin Lv, Guofu Huang
Pages: 2805-2810
Published online on: 22 February 2017

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Article

Downregulation of FKBP14 by RNA interference inhibits the proliferation, adhesion and invasion of gastric cancer cells

Ruizhong Wang, Hua Fang, Qin Fang
Pages: 2811-2816
Published online on: 28 February 2017

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Article

Hsp90 inhibitor SY‑016 induces G2/M arrest and apoptosis in paclitaxel-resistant human ovarian cancer cells

Hyun Gyo Lee, Won Jin Park, So Jin Shin, Sang Hoon Kwon, Soon Do Cha, Young Ho Seo, Ju Hui Jeong, Ji Yoon Lee, Chi Heum Cho
Pages: 2817-2822
Published online on: 01 March 2017

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Methylation pattern of preferentially expressed antigen of melanoma in acute myeloid leukemia and myelodysplastic syndromes

Ya‑Zhen Qin, Yan‑Huan Zhang, Xiao‑Ying Qin, Hong‑Hu Zhu
Pages: 2823-2830
Published online on: 28 February 2017

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Article

Incidence trends in high-grade primary brain tumors in males and females

Jonas Nilsson, Georg Holgersson, Tobias Carlsson, Roger Henriksson, Stefan Bergström, Michael Bergqvist
Pages: 2831-2837
Published online on: 23 February 2017

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Oridonin induces G2/M cell cycle arrest and apoptosis via the PI3K/Akt signaling pathway in hormone-independent prostate cancer cells

Jianlei Lu, Xiang Chen, Shuang Qu, Bing Yao, Yuexin Xu, Jiahui Wu, Yucui Jin, Changyan Ma
Pages: 2838-2846
Published online on: 20 February 2017

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PARP inhibition sensitizes endometrial cancer cells to paclitaxel-induced apoptosis

Christine Dinkic, Friederike Jahn, Marek Zygmunt, Florian Schuetz, Joachim Rom, Christof Sohn, Herbert Fluhr
Pages: 2847-2851
Published online on: 01 March 2017

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Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu‑Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
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Published online on: 02 June 2026

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[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
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Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
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Published online on: 29 May 2026

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Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

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A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

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Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

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Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

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Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

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Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

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Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

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Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

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Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

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Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

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Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

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Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
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Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

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Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review Open Access

Roles of V‑domain Ig suppressor of T‑cell activation‑mediated immunoregulation in tumor immune escape (Review)

Ying Chen, Shubo Wang, Ben Yang, Guohui Wang, Kunning Yang, Meihua Qu
Article Number: 324
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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