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Article Open Access

Effect of SATB1 silencing on the proliferation, invasion and apoptosis of TE-1 esophageal cancer cells

Retraction in: /10.3892/ol.2025.15052
  • Authors:
    • Bo Huang
    • Fei Xiong
    • Siwang Wang
    • Xianping Lang
    • Xiaodong Wang
    • Hongli Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Thoracic Surgery, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, Liaoning 121000, P.R. China, Department of Nephropathy, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, Liaoning 121000, P.R. China
    Copyright: © Huang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2915-2920
    |
    Published online on: March 13, 2017
       https://doi.org/10.3892/ol.2017.5854
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Abstract

The aim of the present study was to investigate the effect of special AT-rich sequence-binding protein-1 (SATB1)-targeted small interfering RNA (siRNA) on the proliferation, invasion and apoptosis of TE‑1 human esophageal cancer cells. SATB1 has been correlated with the metastasis and poor prognosis of colon and breast cancer, but the role of SATB1 in esophageal cancer remains unknown. Therefore, the present study constructed and transfected SATB1‑siRNA into TE‑1 cells in order to knockdown the expression of the SATB1 gene. Western blot analysis, a cell counting kit, transwell chamber assays and flow cytometry were used to assess the effect of SATB1‑siRNA on the proliferation, invasion and apoptosis of cells. The results demonstrated that the expression of the SATB1 gene was efficiently knocked down by SATB1‑siRNA, and that SATB1-siRNA inhibited the proliferation, invasion and apoptosis of TE‑1 cells. Therefore, it was concluded that the SATB1 gene is important in the pathogenesis of human esophageal cancer, and may present a novel therapeutic target for esophageal cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Huang B, Xiong F, Wang S, Lang X, Wang X and Zhou H: Effect of SATB1 silencing on the proliferation, invasion and apoptosis of TE-1 esophageal cancer cells Retraction in /10.3892/ol.2025.15052. Oncol Lett 13: 2915-2920, 2017.
APA
Huang, B., Xiong, F., Wang, S., Lang, X., Wang, X., & Zhou, H. (2017). Effect of SATB1 silencing on the proliferation, invasion and apoptosis of TE-1 esophageal cancer cells Retraction in /10.3892/ol.2025.15052. Oncology Letters, 13, 2915-2920. https://doi.org/10.3892/ol.2017.5854
MLA
Huang, B., Xiong, F., Wang, S., Lang, X., Wang, X., Zhou, H."Effect of SATB1 silencing on the proliferation, invasion and apoptosis of TE-1 esophageal cancer cells Retraction in /10.3892/ol.2025.15052". Oncology Letters 13.5 (2017): 2915-2920.
Chicago
Huang, B., Xiong, F., Wang, S., Lang, X., Wang, X., Zhou, H."Effect of SATB1 silencing on the proliferation, invasion and apoptosis of TE-1 esophageal cancer cells Retraction in /10.3892/ol.2025.15052". Oncology Letters 13, no. 5 (2017): 2915-2920. https://doi.org/10.3892/ol.2017.5854
Copy and paste a formatted citation
x
Spandidos Publications style
Huang B, Xiong F, Wang S, Lang X, Wang X and Zhou H: Effect of SATB1 silencing on the proliferation, invasion and apoptosis of TE-1 esophageal cancer cells Retraction in /10.3892/ol.2025.15052. Oncol Lett 13: 2915-2920, 2017.
APA
Huang, B., Xiong, F., Wang, S., Lang, X., Wang, X., & Zhou, H. (2017). Effect of SATB1 silencing on the proliferation, invasion and apoptosis of TE-1 esophageal cancer cells Retraction in /10.3892/ol.2025.15052. Oncology Letters, 13, 2915-2920. https://doi.org/10.3892/ol.2017.5854
MLA
Huang, B., Xiong, F., Wang, S., Lang, X., Wang, X., Zhou, H."Effect of SATB1 silencing on the proliferation, invasion and apoptosis of TE-1 esophageal cancer cells Retraction in /10.3892/ol.2025.15052". Oncology Letters 13.5 (2017): 2915-2920.
Chicago
Huang, B., Xiong, F., Wang, S., Lang, X., Wang, X., Zhou, H."Effect of SATB1 silencing on the proliferation, invasion and apoptosis of TE-1 esophageal cancer cells Retraction in /10.3892/ol.2025.15052". Oncology Letters 13, no. 5 (2017): 2915-2920. https://doi.org/10.3892/ol.2017.5854
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