|
1
|
Pelosi G, Sonzogni A, De Pas T, Galetta D,
Veronesi G, Spaggiari L, Manzotti M, Fumagalli C, Bresaola E and
Nappi O: Review article: Pulmonary sarcomatoid carcinomas: A
practical overview. Int J Surg Pathol. 18:103–120. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Travis WD, Brambilla E, Müller-Hermelink
HK and Harris CC: World Health Organization Classification of
TumoursPathology and genetics of tumours of the lung, pleura,
thymus and heart. IARC Press; Lyon: pp. 53–58. 2004
|
|
3
|
Dacic S, Finkelstein SD, Sasatomi E,
Swalsky PA and Yousem SA: Molecular pathogenesis of pulmonary
carcinosarcoma as determined by microdissection-based allelotyping.
Am J Surg Pathol. 26:510–516. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Holst VA, Finkelstein S, Colby TV, Myers
JL and Yousem SA: p53 and K-ras mutational genotyping in pulmonary
carcinosarcoma, spindle cell carcinoma, and pulmonary blastoma:
Implications for histogenesis. Am J Surg Pathol. 21:801–811. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Sekine S, Shibata T, Matsuno Y, Maeshima
A, Ishii G, Sakamoto M and Hirohashi S: Beta-Catenin mutations in
pulmonary blastomas: Association with morule formation. J Pathol.
200:214–221. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Blaukovitsch M, Halbwedl I, Kothmaier H,
Gogg-Kammerer M and Popper HH: Sarcomatoid carcinomas of the
lung-are these histogenetically heterogeneous tumors? Virchows
Arch. 449:455–461. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Nakatani Y, Miyagi Y, Takemura T, Oka T,
Yokoi T, Takagi M, Yokoyama S, Kashima K, Hara K, Yamada T, et al:
Aberrant nuclear/cytoplasmic localization and gene mutation of
beta-catenin in classic pulmonary blastoma: Beta-catenin
immunostaining is useful for distinguishing between classic
pulmonary blastoma and a blastomatoid variant of carcinosarcoma. Am
J Surg Pathol. 28:921–927. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Haraguchi S, Fukuda Y, Sugisaki Y and
Yamanaka N: Pulmonary carcinosarcoma: Immunohistochemical and
ultrastructural studies. Pathol Int. 49:903–908. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Hay ED: Organization and fine structure of
epithelium and mesenchyme in the developing chick
embryoEpithelial-mesenchymal interactions. Fleischmajer R and
Billingham RE: Williams & Wilkins; Baltimore, Maryland, USA:
pp. 31–55. 1968
|
|
10
|
Greenburg G and Hay ED: Epithelia
suspended in collagen gels can lose polarity and express
characteristics of migrating mesenchymal cells. J Cell Biol.
95:333–339. 1982. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Miettinen PJ, Ebner R, Lopez AR and
Derynck R: TGF-beta induced transdifferentiation of mammary
epithelial cells to mesenchymal cells: Involvement of type I
receptors. J Cell Biol. 127:2021–2036. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Sommers CL, Thompson EW, Torri JA, Kemler
R, Gelmann EP and Byers SW: Cell adhesion molecule uvomorulin
expression in human breast cancer cell lines: Relationship to
morphology and invasive capacities. Cell Growth Differ. 2:365–372.
1991.PubMed/NCBI
|
|
13
|
Oka H, Shiozaki H, Kobayashi K, Inoue M,
Tahara H, Kobayashi T, Takatsuka Y, Matsuyoshi N, Hirano S,
Takeichi M, et al: Expression of E-cadherin cell adhesion molecules
in human breast cancer tissues and its relationship to metastasis.
Cancer Res. 53:1696–1701. 1993.PubMed/NCBI
|
|
14
|
Burdsal CA, Damsky CH and Pedersen RA: The
role of E-cadherin and integrins in mesoderm differentiation and
migration at the mammalian primitive streak. Development.
118:829–844. 1993.PubMed/NCBI
|
|
15
|
Thompson EW, Torri J, Sabol M, Sommers CL,
Byers S, Valverius EM, Martin GR, Lippman ME, Stampfer MR and
Dickson RB: Oncogene-induced basement membrane invasiveness in
human mammary epithelial cells. Clin Exp Metastasis. 12:181–194.
1994. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Cano A, Pérez-Moreno MA, Rodrigo I,
Locascio A, Blanco MJ, del Barrio MG, Portillo F and Nieto MA: The
transcription factor snail controls epithelial-mesenchymal
transitions by repressing E-cadherin expression. Nat Cell Biol.
2:76–83. 2000. View
Article : Google Scholar : PubMed/NCBI
|
|
17
|
Bolós V, Peinado H, Pérez-Moreno MA, Fraga
MF, Esteller M and Cano A: The transcription factor Slug represses
E-cadherin expression and induces epithelial to mesenchymal
transitions: A comparison with Snail and E47 repressors. J Cell
Sci. 116:499–511. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Blechschmidt K, Sassen S, Schmalfeldt B,
Schuster T, Höfler H and Becker KF: The E-cadherin repressor Snail
is associated with lower overall survival of ovarian cancer
patients. Br J Cancer. 98:489–495. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Shih JY, Tsai MF, Chang TH, Chang YL, Yuan
A, Yu CJ, Lin SB, Liou GY, Lee ML, Chen JJ, et al: Transcription
repressor slug promotes carcinoma invasion and predicts outcome of
patients with lung adenocarcinoma. Clin Cancer Res. 11:8070–8078.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Haslehurst AM, Koti M, Dharsee M, Nuin P,
Evans K, Geraci J, Childs T, Chen J, Li J, Weberpals J, et al: EMT
transcription factors snail and slug directly contribute to
cisplatin resistance in ovarian cancer. BMC Cancer. 12:912012.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Chambers I, Colby D, Robertson M, Nichols
J, Lee S, Tweedie S and Smith A: Functional expression cloning of
Nanog, a pluripotency sustaining factor in embryonic stem cells.
Cell. 113:643–655. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Mitsui K, Tokuzawa Y, Itoh H, Segawa K,
Murakami M, Takahashi K, Maruyama M, Maeda M and Yamanaka S: The
homeoprotein Nanog is required for maintenance of pluripotency in
mouse epiblast and ES cells. Cell. 113:631–642. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Chiou SH, Wang ML, Chou YT, Chen CJ, Hong
CF, Hsieh WJ, Chang HT, Chen YS, Lin TW, Hsu HS and Wu CW:
Coexpression of Oct4 and Nanog enhances malignancy in lung
adenocarcinoma by inducing cancer stem cell-like properties and
epithelial-mesenchymal transdifferentiation. Cancer Res.
70:10433–10444. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Li XQ, Yang XL, Zhang G, Wu SP, Deng XB,
Xiao SJ, Liu QZ, Yao KT and Xiao GH: Nuclear β-catenin accumulation
is associated with increased expression of Nanog protein and
predicts poor prognosis of non-small cell lung cancer. J Transl
Med. 11:1142013. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Pirozzi G, Tirino V, Camerlingo R, Franco
R, La Rocca A, Liguori E, Martucci N, Paino F, Normanno N and Rocco
G: Epithelial to mesenchymal transition by TGFβ-1 induction
increases stemness characteristics in primary non small cell lung
cancer cell line. PLoS One. 6:e215482011. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Goldstraw P, Crowley J, Chansky K, Giroux
DJ, Groome PA, Rami-Porta R, Postmus PE, Rusch V and Sobin L:
International Association for the Study of Lung Cancer
International Staging Committee; Participating Institutions: The
IASLC lung cancer staging project: Proposals for the revision of
the TNM stage groupings in the forthcoming (seventh) edition of the
TNM Classification of malignant tumours. J Thorac Oncol. 2:706–714.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Oken MM, Creech RH, Tormey DC, Horton J,
Davis TE, McFadden ET and Carbone PP: Toxicity and response
criteria of the Eastern Cooperative Oncology Group. Am J Clin
Oncol. 5:649–655. 1982. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Meng HM, Zheng P, Wang XY, Liu C, Sui HM,
Wu SJ, Zhou J, Ding YQ and Li J: Over-expression of Nanog predicts
tumour progression and poor prognosis in colorectal cancer. Cancer
Biol Ther. 9:295–302. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Greenwood M: The natural duration of
cancerReports on Public Health and Medical Subjects. No. 33. Her
Majesty's Stationery Office; London: pp. 1–26. 1926
|
|
30
|
Brookmeyer R and Crowley J: A confidence
interval for the median survival time. Biometrics. 38:29–41. 1982.
View Article : Google Scholar
|
|
31
|
Kim SH, Kim JM, Shin MH, Kim CW, Huang SM,
Kang DW, Suh KS, Yi ES and Kim KH: Correlation of
epithelial-mesenchymal transition markers with clinicopathologic
parameters in adenocarcinomas and squamous cell carcinoma of the
lung. Histol Histopathol. 27:581–591. 2012.PubMed/NCBI
|
|
32
|
Vicent S, Garayoa M, López-Picazo JM,
Lozano MD, Toledo G, Thunnissen FB, Manzano RG and Montuenga LM:
Mitogen-activated protein kinase phosphatase-1 is overexpressed in
non-small cell lung cancer and is an independent predictor of
outcome in patients. Clin Cancer Res. 10:3639–3649. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Du Y, Ma C, Wang Z, Liu Z, Liu H and Wang
T: Nanog, a novel prognostic marker for lung cancer. Surg Oncol.
22:224–229. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Gialmanidis IP, Bravou V, Petrou I, Kourea
H, Mathioudakis A, Lilis I and Papadaki H: Expression of Bmi1,
FoxF1, Nanog, and γ-catenin in relation to hedgehog signaling
pathway in human non-small-cell lung cancer. Lung. 191:511–521.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Luo W, Li S, Peng B, Ye Y, Deng X and Yao
K: Embryonic stem cells markers SOX2, OCT4 and Nanog expression and
their correlations with epithelial-mesenchymal transition in
nasopharyngeal carcinoma. PLoS One. 8:e563242013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Chen SF, Lin YS, Jao SW, Chang YC, Liu CL,
Lin YJ and Nieh S: Pulmonary adenocarcinoma in malignant pleural
effusion enriches cancer stem cell properties during metastatic
cascade. PLoS One. 8:e546592013. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Piek E, Moustakas A, Kurisaki A, Heldin CH
and ten Dijke P: TGF-(beta) type I receptor/ALK-5 and Smad proteins
mediate epithelial to mesenchymal transdifferentiation in NMuMG
breast epithelial cells. J Cell Sci. 112:4557–4568. 1999.PubMed/NCBI
|
|
38
|
Bhowmick NA, Ghiassi M, Bakin A, Aakre M,
Lundquist CA, Engel ME, Arteaga CL and Moses HL: Transforming
growth factor-beta1 mediates epithelial to mesenchymal
transdifferentiation through a RhoA-dependent mechanism. Mol Biol
Cell. 12:27–36. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Bakin AV, Tomlinson AK, Bhowmick NA, Moses
HL and Arteaga CL: Phosphatidylinositol 3-kinase function is
required for transforming growth factor beta-mediated epithelial to
mesenchymal transition and cell migration. J Biol Chem.
275:36803–36810. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Kim K, Lu Z and Hay ED: Direct evidence
for a role of beta-catenin/LEF-1 signaling pathway in induction of
EMT. Cell Biol Int. 26:463–476. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Bhowmick NA, Zent R, Ghiassi M, McDonnell
M and Moses HL: Integrin beta 1 signaling is necessary for
transforming growth factor-beta activation of p38MAPK and
epithelial plasticity. J Biol Chem. 276:46707–46713. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Do HJ, Lim HY and Kim JH, Song H, Chung HM
and Kim JH: An intact homeobox domain is required for complete
nuclear localization of human Nanog. Biochem Biophys Res Commun.
353:770–775. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Chang DF, Tsai SC, Wang XC, Xia P,
Senadheera D and Lutzko C: Molecular characterization of the human
NANOG protein. Stem Cells. 27:812–821. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Ezeh UI, Turek PJ, Reijo RA and Clark AT:
Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are
expressed in both seminoma and breast carcinoma. Cancer.
104:2255–2265. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Miyazawa K, Tanaka T, Nakai D, Morita N
and Suzuki K: Immunohistochemical expression of four different stem
cell markers in prostate cancer: High expression of NANOG in
conjunction with hypoxia-inducible factor-1α expression is involved
in prostate epithelial malignancy. Oncol Lett. 8:985–992.
2014.PubMed/NCBI
|
|
46
|
Pan Y, Jiao J, Zhou C, Cheng Q, Hu Y and
Chen H: Nanog is highly expressed in ovarian serous
cystadenocarcinoma and correlated with clinical stage and
pathological grade. Pathobiology. 77:283–288. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Gu TT, Liu SY and Zheng PS: Cytoplasmic
NANOG-positive stromal cells promote human cervical cancer
progression. Am J Pathol. 181:652–661. 2012. View Article : Google Scholar : PubMed/NCBI
|
