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Article Open Access

Evaluation of microRNA‑205 expression as a potential triage marker for patients with low‑grade squamous intraepithelial lesions

  • Authors:
    • Hong Xie
    • Ingrid Norman
    • Anders Hjerpe
    • Tomislav Vladic
    • Catharina Larsson
    • Weng‑Onn Lui
    • Ellinor Östensson
    • Sonia Andersson
  • View Affiliations / Copyright

    Affiliations: Tianjin Life Science Research Center and Department of Pathogen Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, P.R. China, Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynecology, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden, Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden, Department of Women's and Children's Health, Division of Obstetrics and Gynecology, Karolinska Institutet, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden, Department of Oncology‑Pathology, Karolinska Institutet, Cancer Center Karolinska, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden
    Copyright: © Xie et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3586-3598
    |
    Published online on: March 24, 2017
       https://doi.org/10.3892/ol.2017.5909
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Abstract

High-risk human papillomavirus (HPV) testing is a recommended triage approach for females with atypical squamous cells of undetermined significance (ASCUS), but due to its poor specificity this approach is not recommended for patients with low‑grade squamous intraepithelial lesions (LSIL). The objective of the current study was to determine microRNA (miR)‑205 expression levels in liquid‑based cytology (LBC) samples, and evaluate their ability to predict cervical intraepithelial neoplasia grade 2/3 or worse (CIN2/3+) in females with minor cytological abnormalities. LBC samples were obtained from patients attending the Swedish Cervical Cancer Screening Program. The Mann‑Whitney U test, one‑way analysis of variance, Kruskal‑Wallis test, Spearman rank order correlation analysis, and Pearson's χ2 test were used to assess the results. Accuracy analyses indicated that high miR‑205 expression had a significantly higher specificity to high‑risk HPV testing, and a sensitivity similar to that of high‑risk HPV testing to predict CIN2+ and CIN3+ in women with LSIL, but not those with high‑grade squamous intraepithelial lesions. Although further research is required for females with LSIL, miR‑205 expression in LBC samples may be a novel triage marker for, or a beneficial supplement to high‑risk‑HPV testing in these patients.
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1 

Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM: Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar : PubMed/NCBI

2 

The National Board of Health and Welfare: Cancer incidence in Sweden 2008. The National Board of Health and Welfare. Stockholm: 2009.

3 

National Quality Register for Cervical Screening: Prevention of cervical cancer in Sweden. Annual report 2014 with data to 2013. National Quality Register for Cervical Screening. (Stockholm, Swedish). 2014.

4 

Bosch FX and Muñoz N: The viral etiology of cervical cancer. Virus Res. 89:183–190. 2002. View Article : Google Scholar : PubMed/NCBI

5 

Woodman CB, Collins SI and Young LS: The natural history of cervical HPV infection: Unresolved issues. Nat Rev Cancer. 7:11–22. 2007. View Article : Google Scholar : PubMed/NCBI

6 

Münger K: Disruption of oncogene/tumor suppressor networks during human carcinogenesis. Cancer Invest. 20:71–81. 2002. View Article : Google Scholar : PubMed/NCBI

7 

Pett M and Coleman N: Integration of high-risk human papillomavirus: A key event in cervical carcinogenesis? J Pathol. 212:356–367. 2007. View Article : Google Scholar : PubMed/NCBI

8 

Imaoka H, Toiyama Y, Okigami M, Yasuda H, Saigusa S, Ohi M, Tanaka K, Inoue Y, Mohri Y and Kusunoki M: Circulating microRNA-203 predicts metastases, early recurrence and poor prognosis in human gastric cancer. Gastric Cancer. 19:744–753. 2016. View Article : Google Scholar : PubMed/NCBI

9 

Naucler P, Ryd W, Törnberg S, Strand A, Wadell G, Elfgren K, Rådberg T, Strander B, Johansson B, Forslund O, et al: Human papillomavirus and Papanicolaou tests to screen for cervical cancer. N Engl J Med. 357:1589–1597. 2007. View Article : Google Scholar : PubMed/NCBI

10 

Giorgi-Rossi P, Franceschi S and Ronco G: HPV prevalence and accuracy of HPV testing to detect high-grade cervical intraepithelial neoplasia. Int J Cancer. 130:1387–1394. 2012. View Article : Google Scholar : PubMed/NCBI

11 

Bergström R, Sparén P and Adami HO: Trends in cancer of the cervix uteri in Sweden following cytological screening. Br J Cancer. 81:159–166. 1999. View Article : Google Scholar : PubMed/NCBI

12 

Cuzick J, Clavel C, Petry KU, Meijer CJ, Hoyer H, Ratnam S, Szarewski A, Birembaut P, Kulasingam S, Sasieni P and Iftner T: Overview of the European and North American studies on HPV testing in primary cervical cancer screening. Int J Cancer. 119:1095–1101. 2006. View Article : Google Scholar : PubMed/NCBI

13 

Nanda K, McCrory DC, Myers ER, Bastian LA, Hasselblad V, Hickey JD and Matchar DB: Accuracy of the Papanicolaou test in screening for and follow-up of cervical cytologic abnormalities: A systematic review. Ann Intern Med. 132:810–819. 2000. View Article : Google Scholar : PubMed/NCBI

14 

Strander B, Andersson-Ellström A, Milsom I, Rådberg T and Ryd W: Liquid-based cytology versus conventional Papanicolaou smear in an organized screening program: A prospective randomized study. Cancer. 111:285–291. 2007. View Article : Google Scholar : PubMed/NCBI

15 

Persson M, Elfström KM, Brismar Wendel S, Weiderpass E and Andersson S: Triage of HR-HPV positive women with minor cytological abnormalities: A comparison of mRNA testing, HPV DNA testing and repeat cytology using a 4-year follow-up of a population-based study. PLoS One. 9:e900232014. View Article : Google Scholar : PubMed/NCBI

16 

Bartel DP: MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell. 116:281–297. 2004. View Article : Google Scholar : PubMed/NCBI

17 

Lui WO, Pourmand N, Patterson BK and Fire A: Patterns of known and novel small RNAs in human cervical cancer. Cancer Res. 67:6031–6043. 2007. View Article : Google Scholar : PubMed/NCBI

18 

Wang X, Tang S, Le SY, Lu R, Rader JS, Meyers C and Zheng ZM: Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth. PLoS One. 3:e25572008. View Article : Google Scholar : PubMed/NCBI

19 

Witten D, Tibshirani R, Gu SG, Fire A and Lui WO: Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. BMC Biol. 8:582010. View Article : Google Scholar : PubMed/NCBI

20 

Xie H, Zhao Y, Caramuta S, Larsson C and Lui WO: MiR-205 expression promotes cell proliferation and migration of human cervical cancer cells. PLoS One. 7:e469902012. View Article : Google Scholar : PubMed/NCBI

21 

Hagrass HA, Sharaf S, Pasha HF, Tantawy EA, Mohamed RH and Kassem R: Circulating microRNAs-a new horizon in molecular diagnosis of breast cancer. Genes Cancer. 6:281–287. 2015.PubMed/NCBI

22 

He Y, Lin J, Kong D, Huang M, Xu C, Kim TK, Etheridge A, Luo Y, Ding Y and Wang K: Current state of circulating microRNAs as cancer biomarkers. Clin Chem. 61:1138–1155. 2015. View Article : Google Scholar : PubMed/NCBI

23 

Lin XJ, Chong Y, Guo ZW, Xie C, Yang XJ, Zhang Q, Li SP, Xiong Y, Yuan Y, Min J, et al: A serum microRNA classifier for early detection of hepatocellular carcinoma: A multicentre, retrospective, longitudinal biomarker identification study with a nested case-control study. Lancet Oncol. 16:804–815. 2015. View Article : Google Scholar : PubMed/NCBI

24 

Mu YP, Sun WJ, Lu CW and Su XL: MicroRNAs may serve as emerging molecular biomarkers for diagnosis and prognostic assessment or as targets for therapy in gastric cancer. Asian Pac J Cancer Prev. 16:4813–4820. 2015. View Article : Google Scholar : PubMed/NCBI

25 

Nonaka R, Miyake Y, Hata T, Kagawa Y, Kato T, Osawa H, Nishimura J, Ikenaga M, Murata K, Uemura M, et al: Circulating miR-103 and miR-720 as novel serum biomarkers for patients with colorectal cancer. Int J Oncol. 47:1097–1102. 2015.PubMed/NCBI

26 

Yu J, Jin L, Jiang L, Gao L, Zhou J, Hu Y, Li W, Zhi Q and Zhu X: Serum miR-372 is a diagnostic and prognostic biomarker in patients with early colorectal cancer. Anticancer Agents Med Chem. 16:424–431. 2016. View Article : Google Scholar : PubMed/NCBI

27 

Orang AV, Safaralizadeh R, Hosseinpour Feizi MA and Somi MH: Diagnostic and prognostic value of miR-205 in colorectal cancer. Asian Pac J Cancer Prev. 15:4033–4037. 2014. View Article : Google Scholar : PubMed/NCBI

28 

Zheng H, Zhang L, Zhao Y, Yang D, Song F, Wen Y, Hao Q, Hu Z, Zhang W and Chen K: Plasma miRNAs as diagnostic and prognostic biomarkers for ovarian cancer. PLoS One. 8:e778532013. View Article : Google Scholar : PubMed/NCBI

29 

Yue X, Lan F, Hu M, Pan Q, Wang Q and Wang J: Downregulation of serum microRNA-205 as a potential diagnostic and prognostic biomarker for human glioma. J Neurosurg. 124:122–128. 2016. View Article : Google Scholar : PubMed/NCBI

30 

Ma Q, Wan G, Wang S, Yang W, Zhang J and Yao X: Serum microRNA-205 as a novel biomarker for cervical cancer patients. Cancer Cell Int. 14:812014. View Article : Google Scholar : PubMed/NCBI

31 

Zhao S, Yao D, Chen J and Ding N: Circulating miRNA-20a and miRNA-203 for screening lymph node metastasis in early stage cervical cancer. Genet Test Mol Biomarkers. 17:631–636. 2013. View Article : Google Scholar : PubMed/NCBI

32 

Malta M, Ribeiro J, Monteiro P, Loureiro J, Medeiros R and Sousa H: Let-7c is a candidate biomarker for cervical intraepithelial lesions: A pilot study. Mol Diagn Ther. 19:191–196. 2015. View Article : Google Scholar : PubMed/NCBI

33 

Tian Q, Li Y, Wang F, Li Y, Xu J, Shen Y, Ye F, Wang X, Cheng X, Chen Y, et al: MicroRNA detection in cervical exfoliated cells as a triage for human papillomavirus-positive women. J Natl Cancer Inst. 106:pii: dju241. 2014. View Article : Google Scholar : PubMed/NCBI

34 

Fröberg M, Johansson B, Hjerpe A and Andersson S: Human papillomavirus ‘reflex’ testing as a screening method in cases of minor cytological abnormalities. Br J Cancer. 99:563–568. 2008. View Article : Google Scholar : PubMed/NCBI

35 

Solomon D, Davey D, Kurman R, Moriarty A, O'Connor D, Prey M, Raab S, Sherman M, Wilbur D, Wright T Jr, et al: The 2001 bethesda system: Terminology for reporting results of cervical cytology. JAMA. 287:2114–2119. 2002. View Article : Google Scholar : PubMed/NCBI

36 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI

37 

Canavan TP and Doshi NR: Cervical cancer. Am Fam Physician. 61:1369–1376. 2000.PubMed/NCBI

38 

Esquela-Kerscher A and Slack FJ: Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer. 6:259–269. 2006. View Article : Google Scholar : PubMed/NCBI

39 

Lee YS and Dutta A: MicroRNAs in cancer. Annu Rev Pathol. 4:199–227. 2009. View Article : Google Scholar : PubMed/NCBI

40 

Qin AY, Zhang XW, Liu L, Yu JP, Li H, Wang SZ, Ren XB and Cao S: MiR-205 in cancer: An angel or a devil? Eur J Cell Biol. 92:54–60. 2013. View Article : Google Scholar : PubMed/NCBI

41 

Martinez I, Gardiner AS, Board KF, Monzon FA, Edwards RP and Khan SA: Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells. Oncogene. 27:2575–2582. 2008. View Article : Google Scholar : PubMed/NCBI

42 

Wang X, Wang HK, Li Y, Hafner M, Banerjee NS, Tang S, Briskin D, Meyers C, Chow LT, Xie X, et al: MicroRNAs are biomarkers of oncogenic human papillomavirus infections. Proc Natl Acad Sci USA. 111:4262–4267. 2014. View Article : Google Scholar : PubMed/NCBI

43 

Nielsen BS: MicroRNA in situ hybridization. Methods Mol Biol. 822:67–84. 2012. View Article : Google Scholar : PubMed/NCBI

44 

Ge J, Zhang LL, Liu SJ, Yu RQ and Chu X: A highly sensitive target-primed rolling circle amplification (TPRCA) method for fluorescent in situ hybridization detection of microRNA in tumor cells. Anal Chem. 86:1808–1815. 2014. View Article : Google Scholar : PubMed/NCBI

45 

Wu M, Piccini M, Koh CY, Lam KS and Singh AK: Single cell microRNA analysis using microfluidic flow cytometry. PLoS One. 8:e550442013. View Article : Google Scholar : PubMed/NCBI

46 

Wu M, Piccini ME and Singh AK: MiRNA detection at single-cell resolution using microfluidic LNA flow-FISH. Methods Mol Biol. 1211:245–260. 2014. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Xie H, Norman I, Hjerpe A, Vladic T, Larsson C, Lui WO, Östensson E and Andersson S: Evaluation of microRNA‑205 expression as a potential triage marker for patients with low‑grade squamous intraepithelial lesions. Oncol Lett 13: 3586-3598, 2017.
APA
Xie, H., Norman, I., Hjerpe, A., Vladic, T., Larsson, C., Lui, W. ... Andersson, S. (2017). Evaluation of microRNA‑205 expression as a potential triage marker for patients with low‑grade squamous intraepithelial lesions. Oncology Letters, 13, 3586-3598. https://doi.org/10.3892/ol.2017.5909
MLA
Xie, H., Norman, I., Hjerpe, A., Vladic, T., Larsson, C., Lui, W., Östensson, E., Andersson, S."Evaluation of microRNA‑205 expression as a potential triage marker for patients with low‑grade squamous intraepithelial lesions". Oncology Letters 13.5 (2017): 3586-3598.
Chicago
Xie, H., Norman, I., Hjerpe, A., Vladic, T., Larsson, C., Lui, W., Östensson, E., Andersson, S."Evaluation of microRNA‑205 expression as a potential triage marker for patients with low‑grade squamous intraepithelial lesions". Oncology Letters 13, no. 5 (2017): 3586-3598. https://doi.org/10.3892/ol.2017.5909
Copy and paste a formatted citation
x
Spandidos Publications style
Xie H, Norman I, Hjerpe A, Vladic T, Larsson C, Lui WO, Östensson E and Andersson S: Evaluation of microRNA‑205 expression as a potential triage marker for patients with low‑grade squamous intraepithelial lesions. Oncol Lett 13: 3586-3598, 2017.
APA
Xie, H., Norman, I., Hjerpe, A., Vladic, T., Larsson, C., Lui, W. ... Andersson, S. (2017). Evaluation of microRNA‑205 expression as a potential triage marker for patients with low‑grade squamous intraepithelial lesions. Oncology Letters, 13, 3586-3598. https://doi.org/10.3892/ol.2017.5909
MLA
Xie, H., Norman, I., Hjerpe, A., Vladic, T., Larsson, C., Lui, W., Östensson, E., Andersson, S."Evaluation of microRNA‑205 expression as a potential triage marker for patients with low‑grade squamous intraepithelial lesions". Oncology Letters 13.5 (2017): 3586-3598.
Chicago
Xie, H., Norman, I., Hjerpe, A., Vladic, T., Larsson, C., Lui, W., Östensson, E., Andersson, S."Evaluation of microRNA‑205 expression as a potential triage marker for patients with low‑grade squamous intraepithelial lesions". Oncology Letters 13, no. 5 (2017): 3586-3598. https://doi.org/10.3892/ol.2017.5909
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