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Article

Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis

  • Authors:
    • Qun Lu
    • Junlong Zhuang
    • Hongqian Guo
  • View Affiliations / Copyright

    Affiliations: Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu 210008, P.R. China
  • Pages: 4521-4525
    |
    Published online on: April 4, 2017
       https://doi.org/10.3892/ol.2017.5981
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Abstract

The simultaneous occurrence of renal cell carcinoma (RCC) and urothelial carcinoma (UC) in the same kidney is extraordinarily rare, and is also known as multiple primary malignant tumors. The present study reports the case of a 76‑year‑old female with synchronous ipsilateral RCC and UC of the renal pelvis, who underwent operation, chemotherapy and reoperation when recurrence of RCC or UC was identified. Cluster of differentiation 44 (CD44) is one of the promising markers for identifying cancer stem cells in various solid tumors, along with aldehyde dehydrogenase 1 A1 (ALDH1A1). Detection of CD44 and ALDH1A1 prior to and subsequent to chemotherapy could provide useful prognostic information. New treatments against the cancer stem cells fraction should be used in combination with chemotherapy to improve the outcome for patients with overexpression of CSC markers.
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Copy and paste a formatted citation
Spandidos Publications style
Lu Q, Zhuang J and Guo H: Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis. Oncol Lett 13: 4521-4525, 2017.
APA
Lu, Q., Zhuang, J., & Guo, H. (2017). Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis. Oncology Letters, 13, 4521-4525. https://doi.org/10.3892/ol.2017.5981
MLA
Lu, Q., Zhuang, J., Guo, H."Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis". Oncology Letters 13.6 (2017): 4521-4525.
Chicago
Lu, Q., Zhuang, J., Guo, H."Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis". Oncology Letters 13, no. 6 (2017): 4521-4525. https://doi.org/10.3892/ol.2017.5981
Copy and paste a formatted citation
x
Spandidos Publications style
Lu Q, Zhuang J and Guo H: Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis. Oncol Lett 13: 4521-4525, 2017.
APA
Lu, Q., Zhuang, J., & Guo, H. (2017). Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis. Oncology Letters, 13, 4521-4525. https://doi.org/10.3892/ol.2017.5981
MLA
Lu, Q., Zhuang, J., Guo, H."Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis". Oncology Letters 13.6 (2017): 4521-4525.
Chicago
Lu, Q., Zhuang, J., Guo, H."Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis". Oncology Letters 13, no. 6 (2017): 4521-4525. https://doi.org/10.3892/ol.2017.5981
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