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Case Report

Pulmonary enteric adenocarcinoma with pancreatic metastasis: A case report

  • Authors:
    • Wen‑Wen Sun
    • Zhi‑Hong Xu
    • Chao-Fu Wang
    • Fang Wu
    • Jiu‑Mei Cao
    • Pei‑Jing Cui
    • Wei Huang
    • Xiao‑Long Jin
    • Biao Li
    • Ke‑Min Chen
    • Bei‑Li Gao
    • Jia‑An Hu
  • View Affiliations / Copyright

    Affiliations: Department of Geriatrics, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, P.R. China, Department of Pathology, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, P.R. China, Department of Radiology, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, P.R. China, Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, P.R. China, Department of Respiration, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, P.R. China
  • Pages: 4651-4656
    |
    Published online on: April 20, 2017
       https://doi.org/10.3892/ol.2017.6060
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Abstract

Pulmonary enteric adenocarcinoma is a markedly rare pathological type of lung adenocarcinoma. As the pancreas is a relatively uncommon site for metastasis, the present case is even more unusual. A 62‑year‑old male was admitted to hospital following the identification of masses in the left chest wall, right abdominal wall and right upper limb, but with no respiratory symptoms. Computed tomography (CT) of the chest revealed a lump in the lung and a mass in the left chest wall, and 18F‑fluorodeoxyglucose (18F‑FDG) uptake by the lumps was increased. An enhanced abdominal CT revealed a hypodense and homogeneous mass on the head of the pancreas, which was slightly enhanced compared with normal pancreatic tissue. In addition, the 18F‑FDG uptake of the lesion was increased and the standardized uptake value (SUV) delayed was not evidently decreased compared with SUVearly. A number of other abnormal metabolic lesions were also identified using positron emission tomography/CT, whereas no abnormal 18F‑FDG uptake was identified in the gastrointestinal organ. Furthermore, rectocolonoscopy was performed to exclude diagnosis of metastatic colorectal adenocarcinoma. The hematoxylin‑ and eosin‑stained smears of the masses in the right lung and left chest demonstrated an enteric pattern, which shared morphological and immunohistochemical (IHC) features with those of colorectal adenocarcinoma. The IHC detection revealed that the lesions in the right lung were positive for cytokeratin 7 (CK7), and negative for CK20 and thyroid transcription factor 1 (TTF‑1), and the expression of caudal type homeobox 2 (CDX2) was weakly positive; the masses in the left chest wall were positive for CK7, negative for TTF‑1, and CK20 and CDX2 were weakly expressed.
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Copy and paste a formatted citation
Spandidos Publications style
Sun WW, Xu ZH, Wang C, Wu F, Cao JM, Cui PJ, Huang W, Jin XL, Li B, Chen KM, Chen KM, et al: Pulmonary enteric adenocarcinoma with pancreatic metastasis: A case report. Oncol Lett 13: 4651-4656, 2017.
APA
Sun, W., Xu, Z., Wang, C., Wu, F., Cao, J., Cui, P. ... Hu, J. (2017). Pulmonary enteric adenocarcinoma with pancreatic metastasis: A case report. Oncology Letters, 13, 4651-4656. https://doi.org/10.3892/ol.2017.6060
MLA
Sun, W., Xu, Z., Wang, C., Wu, F., Cao, J., Cui, P., Huang, W., Jin, X., Li, B., Chen, K., Gao, B., Hu, J."Pulmonary enteric adenocarcinoma with pancreatic metastasis: A case report". Oncology Letters 13.6 (2017): 4651-4656.
Chicago
Sun, W., Xu, Z., Wang, C., Wu, F., Cao, J., Cui, P., Huang, W., Jin, X., Li, B., Chen, K., Gao, B., Hu, J."Pulmonary enteric adenocarcinoma with pancreatic metastasis: A case report". Oncology Letters 13, no. 6 (2017): 4651-4656. https://doi.org/10.3892/ol.2017.6060
Copy and paste a formatted citation
x
Spandidos Publications style
Sun WW, Xu ZH, Wang C, Wu F, Cao JM, Cui PJ, Huang W, Jin XL, Li B, Chen KM, Chen KM, et al: Pulmonary enteric adenocarcinoma with pancreatic metastasis: A case report. Oncol Lett 13: 4651-4656, 2017.
APA
Sun, W., Xu, Z., Wang, C., Wu, F., Cao, J., Cui, P. ... Hu, J. (2017). Pulmonary enteric adenocarcinoma with pancreatic metastasis: A case report. Oncology Letters, 13, 4651-4656. https://doi.org/10.3892/ol.2017.6060
MLA
Sun, W., Xu, Z., Wang, C., Wu, F., Cao, J., Cui, P., Huang, W., Jin, X., Li, B., Chen, K., Gao, B., Hu, J."Pulmonary enteric adenocarcinoma with pancreatic metastasis: A case report". Oncology Letters 13.6 (2017): 4651-4656.
Chicago
Sun, W., Xu, Z., Wang, C., Wu, F., Cao, J., Cui, P., Huang, W., Jin, X., Li, B., Chen, K., Gao, B., Hu, J."Pulmonary enteric adenocarcinoma with pancreatic metastasis: A case report". Oncology Letters 13, no. 6 (2017): 4651-4656. https://doi.org/10.3892/ol.2017.6060
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