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Case Report

Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report

  • Authors:
    • Run‑Song Jiang
    • Zheng‑Yan Zhao
  • View Affiliations / Copyright

    Affiliations: Department of Reconstructive Plastic Surgery, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, P.R. China
  • Pages: 4887-4891
    |
    Published online on: April 20, 2017
       https://doi.org/10.3892/ol.2017.6064
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Abstract

Kasabach-Merritt syndrome (KMS) is a rare type of vascular tumor associated with a severely decreased platelet count. No standard guidelines for the treatment of the disease have been established so far. In the present study, a 1‑year‑old pediatric patient with KMS arising from tufted angioma was successfully and variously treated with steroids, vincristine, surgery and propranolol for 18 months. Systemic steroids stabilized the platelet count stable, while vincristine reduced the size of the tumor. Due to unpredictable response, the patient was operated. Combination of vincristine and propranolol was introduced post‑surgery to improve the severely low platelet count of the patient. Following multimodal therapy for 18 months, there has been no evidence of recurrence or metastasis during 2 years of follow‑up. Currently, the patient is alive and well. The management of KMS presents a challenge, and well‑designed studies are required to clearly determine the benefits and risks of multidisciplinary treatment.
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Copy and paste a formatted citation
Spandidos Publications style
Jiang RS and Zhao ZY: Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report. Oncol Lett 13: 4887-4891, 2017.
APA
Jiang, R., & Zhao, Z. (2017). Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report. Oncology Letters, 13, 4887-4891. https://doi.org/10.3892/ol.2017.6064
MLA
Jiang, R., Zhao, Z."Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report". Oncology Letters 13.6 (2017): 4887-4891.
Chicago
Jiang, R., Zhao, Z."Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report". Oncology Letters 13, no. 6 (2017): 4887-4891. https://doi.org/10.3892/ol.2017.6064
Copy and paste a formatted citation
x
Spandidos Publications style
Jiang RS and Zhao ZY: Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report. Oncol Lett 13: 4887-4891, 2017.
APA
Jiang, R., & Zhao, Z. (2017). Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report. Oncology Letters, 13, 4887-4891. https://doi.org/10.3892/ol.2017.6064
MLA
Jiang, R., Zhao, Z."Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report". Oncology Letters 13.6 (2017): 4887-4891.
Chicago
Jiang, R., Zhao, Z."Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report". Oncology Letters 13, no. 6 (2017): 4887-4891. https://doi.org/10.3892/ol.2017.6064
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