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Article Open Access

Desmoid-type fibromatosis of the breast: A report of 2 cases

  • Authors:
    • Roman Benej
    • Iveta Mečiarová
    • Kamil Pohlodek
  • View Affiliations / Copyright

    Affiliations: Department of Thoracic Surgery, Slovak Medical University of Bratislava, 82606 Bratislava, Slovakia, Alpha Medical Pathology, Ltd., 84101 Bratislava, Slovakia, Second Department of Gynecology and Obstetrics, Comenius University of Bratislava, Faculty of Medicine, 82606 Bratislava, Slovakia
    Copyright: © Benej et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1433-1438
    |
    Published online on: June 7, 2017
       https://doi.org/10.3892/ol.2017.6337
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Abstract

Mammary fibromatosis is a rare and locally aggressive benign tumor of the breast; it originates from fibroblasts and myofibroblasts within the breast parenchyma and does not metastasize. The condition is locally aggressive and has a high rate of recurrence. The etiology of mammary fibromatosis is unknown. Breast imaging examinations are not specific for fibromatosis and often imitate breast cancer. The current study presents 2 cases of women with breast fibromatosis, the first of which exhibited a locally advanced aggressive form of the disease, where breast surgery and en bloc resection of the underlying regions of the thoracic wall were required. In the second case, breast imaging examinations suggested an invasive breast tumor, probably carcinoma, infiltrating the muscles of the chest wall. An ultrasound‑guided core needle biopsy revealed a low‑grade myofibroblastic proliferation consistent with breast fibromatosis. The patient underwent a right quadrantectomy, with a partial resection of the underlying musculature. The patients remain disease‑free at the time of writing. As involvement of the breast in patients with desmoid‑like fibromatosis as rare, the present study reports 2 cases with clinical features and histological findings in order to improve and add to the knowledge of this disease.
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Copy and paste a formatted citation
Spandidos Publications style
Benej R, Mečiarová I and Pohlodek K: Desmoid-type fibromatosis of the breast: A report of 2 cases. Oncol Lett 14: 1433-1438, 2017.
APA
Benej, R., Mečiarová, I., & Pohlodek, K. (2017). Desmoid-type fibromatosis of the breast: A report of 2 cases. Oncology Letters, 14, 1433-1438. https://doi.org/10.3892/ol.2017.6337
MLA
Benej, R., Mečiarová, I., Pohlodek, K."Desmoid-type fibromatosis of the breast: A report of 2 cases". Oncology Letters 14.2 (2017): 1433-1438.
Chicago
Benej, R., Mečiarová, I., Pohlodek, K."Desmoid-type fibromatosis of the breast: A report of 2 cases". Oncology Letters 14, no. 2 (2017): 1433-1438. https://doi.org/10.3892/ol.2017.6337
Copy and paste a formatted citation
x
Spandidos Publications style
Benej R, Mečiarová I and Pohlodek K: Desmoid-type fibromatosis of the breast: A report of 2 cases. Oncol Lett 14: 1433-1438, 2017.
APA
Benej, R., Mečiarová, I., & Pohlodek, K. (2017). Desmoid-type fibromatosis of the breast: A report of 2 cases. Oncology Letters, 14, 1433-1438. https://doi.org/10.3892/ol.2017.6337
MLA
Benej, R., Mečiarová, I., Pohlodek, K."Desmoid-type fibromatosis of the breast: A report of 2 cases". Oncology Letters 14.2 (2017): 1433-1438.
Chicago
Benej, R., Mečiarová, I., Pohlodek, K."Desmoid-type fibromatosis of the breast: A report of 2 cases". Oncology Letters 14, no. 2 (2017): 1433-1438. https://doi.org/10.3892/ol.2017.6337
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