|
1
|
Fire A, Xu S, Montgomery MK, Kostas SA,
Driver SE and Mello CC: Potent and specific genetic interference by
double-stranded RNA in Caenorhabditis elegans. Nature. 391:806–811.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Gandellini P, Folini M, Bandiera R, De
Cesare M, Binda M, Veronese S, Daidone MG, Zunino F and Zaffaroni
N: Down-regulation of human telomerase reverse transcriptase
through specific activation of RNAi pathway quickly results in
cancer cell growth impairment. Biochem Pharmacol. 73:1703–1714.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Harley CB, Futcher AB and Greider CW:
Telomeres shorten during ageing of human fibroblasts. Nature.
345:458–460. 1990. View
Article : Google Scholar : PubMed/NCBI
|
|
4
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hastie ND, Dempster M, Dunlop MG, Thompson
AM, Green DK and Allshire RC: Telomere reduction in human
colorectal carcinoma and with ageing. Nature. 346:866–868. 1990.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
McFadden N, Bailey D, Carrara G, Benson A,
Chaudhry Y, Shortland A, Heeney J, Yarovinsky F, Simmonds P,
Macdonald A and Goodfellow I: Norovirus regulation of the innate
immune response and apoptosis occurs via the product of the
alternative open reading frame 4. PLoS Pathog. 7:e10024132011.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Folini M, Brambilla C, Villa R, Gandellini
P, Vignati S, Paduano F, Daidone MG and Zaffaroni N: Antisense
oligonucleotide-mediated inhibition of hTERT, but not hTERC,
induces rapid cell growth decline and apoptosis in the absence of
telomere shortening in human prostate cancer cells. Eur J Cancer.
41:624–634. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Cong YS, Wright WE and Shay JW: Human
telomerase and its regulation. Microbiol Mol Biol Rev. 66:407–425.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Blackburn EH, Greider CW and Szostak JW:
Telomeres and telomerase: The path from maize, Tetrahymena and
yeast to human cancer and aging. Nat Med. 12:1133–1138. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Zou L, Zhang P, Luo C and Tu Z:
shRNA-targeted hTERT suppress cell proliferation of bladder cancer
by inhibiting telomerase activity. Cancer Chemother Pharmacol.
57:328–334. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Gorbunova V, Seluanov A and Pereira-Smith
OM: Expression of human telomerase (hTERT) does not prevent
stress-induced senescence in normal human fibroblasts but protects
the cells from stress-induced apoptosis and necrosis. J Biol Chem.
277:38540–38549. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Liu K, Hodes RJ and Weng Np: Cutting edge:
Telomerase activation in human T lymphocytes does not require
increase in telomerase reverse transcriptase (hTERT) protein but is
associated with hTERT phosphorylation and nuclear translocation. J
Immunol. 166:4826–4830. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
O'Connor DS, Schechner JS, Adida C, Mesri
M, Rothermel AL, Li F, Nath AK, Pober JS and Altieri DC: Control of
apoptosis during angiogenesis by survivin expression in endothelial
cells. Am J Pathol. 156:393–398. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Porter AG and Jänicke RU: Emerging roles
of caspase-3 in apoptosis. Cell Death Differ. 6:99–104. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Dale-Nagle EA, Satriotomo I and Mitchell
GS: Spinal vascular endothelial growth factor induces phrenic motor
facilitation via extracellular signal-regulated kinase and Akt
signaling. J Neurosci. 31:7682–7690. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Paterniti I, Esposito E, Mazzon E,
Bramanti P and Cuzzocrea S: Evidence for the role of
PI(3)-kinase-AKT-eNOS signalling pathway in secondary inflammatory
process after spinal cord compression injury in mice. Eur J
Neurosci. 33:1411–1420. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Gheysarzadeh A and Yazdanparast R:
Inhibition of H2O2-induced cell death through FOXO1 modulation by
EUK-172 in SK-N-MC cells. Eur J Pharmacol. 697:47–52. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Park HS, Seong KM, Kim JY, Kim CS, Yang
KH, Jin YW and Nam SY: Chronic low-dose radiation inhibits the
cells death by cytotoxic high-dose radiation increasing the level
of AKT and acinus proteins via NF-κB activation. Int J Radiat Biol.
89:371–377. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Yang W, Ju JH, Lee KM, Nam K, Oh S and
Shin I: Protein kinase B/Akt1 inhibits autophagy by down-regulating
UVRAG expression. Exp Cell Res. 319:122–133. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zeng X, Huang Z, Mao X, Wang J, Wu G and
Qiao S: N-carbamylglutamate enhances pregnancy outcome in rats
through activation of the PI3K/PKB/mTOR signaling pathway. PLoS
One. 7:e411922012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Siraskar B, Völkl J, Ahmed MS, Hierlmeier
M, Gu S, Schmid E, Leibrock C, Föller M, Lang UE and Lang F:
Enhanced catecholamine release in mice expressing PKB/SGK-resistant
GSK3. Pflugers Arch. 462:811–819. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Vichalkovski A, Gresko E, Hess D,
Restuccia DF and Hemmings BA: PKB/AKT phosphorylation of the
transcription factor Twist-1 at Ser42 inhibits p53 activity in
response to DNA damage. Oncogene. 29:3554–3565. 2010. View Article : Google Scholar : PubMed/NCBI
|
