Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
August-2017 Volume 14 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2017 Volume 14 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report Open Access

Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report

  • Authors:
    • Pan Liang
    • Xiu‑Chun Ren
    • Jian‑Bo Gao
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan 450052, P.R. China
    Copyright: © Liang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2147-2152
    |
    Published online on: June 22, 2017
       https://doi.org/10.3892/ol.2017.6456
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Primary esophageal natural killer (NK)/T‑cell lymphoma is a markedly rare tumor. There were only 6 cases of the disease identified prior to June 2015. In the present study, the aforementioned cases were validated, and relevant computed tomography (CT) results and clinical features of primary esophageal NK/T‑cell lymphoma were determined, to increase awareness of this type of tumor. CT features and clinical presentations of a patient with pathologically confirmed esophageal NK/T‑cell lymphoma was analyzed. The patient exhibited non‑specific clinical symptoms and CT images revealed diffuse thickening of the entire length of the esophagus. The patient received cycles of systemic chemotherapy and subsequent chest CT images demonstrated prompt and marked shrinkage of the tumor. At the time of writing, the patient has survived for 24 months and experiences a good quality of life without postprandial fullness or difficulty swallowing solid food. In addition, the characteristics of 6 patients with complete clinical features of this type of tumor, on the basis of a review of published studies (online PubMed, Medline, Google Scholar, Chinese Biomedicine Database and China Journal Full Text Database search), were retrospectively analyzed. Although primary esophageal NK/T‑cell lymphoma is a markedly rare tumor, it is considered to be included in differential diagnosis of patients presenting with a fungal or viral infection, therapy‑related mucositis or reflux esophagitis. The final diagnosis of primary esophageal NK/T‑cell lymphoma is on the basis of a combination of clinical, CT and histopathological results.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Wu X, Li P, Zhao J, Yang X, Wang F, Yang YQ, Fang F, Xu Y, Zhang H, Wang WY and Yi C: A clinical study of 115 patients with extranodal natural killer/T-cell lymphoma, nasal type. Clin Oncol (R Coll Radiol). 20:619–625. 2008. View Article : Google Scholar : PubMed/NCBI

2 

Ghimire P, Wu GY and Zhu L: Primary esophageal lymphoma in immunocompetent patients: Two case reports and literature review. World J Radiol. 2:334–338. 2010. View Article : Google Scholar : PubMed/NCBI

3 

Mori T, Komeno T and Ohtani H: Mantle cell lymphoma-like solitary polypoid tumor of the esophagus: A case report. Cases J. 2:66462009. View Article : Google Scholar : PubMed/NCBI

4 

Zhang S, Wang H and Leng DN: Clinicopathological observation on 2 cases of nasal-type NK/T-cell lymphoma in the esophagus. Zhonghua Zhong Liu Za Zhi. 30:767–769. 2008.(In Chinese). PubMed/NCBI

5 

Lee SR, Park EK, Won NH and Kim BS: Esophageal involvement by extranodal natural killer T cell lymphoma, nasal type, mimicking Epstein Barr viral esophagitis in a tonsillar lymphoma patient undergoing chemoradiation therapy. Asia Pac J Clin Oncol. 6:149–154. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Fujihara S, Mori H, Kobara H, Nishiyama N, Kobayashi M and Masaki T: Esophageal natural killer (NK)/T cell lymphoma of true natural killer cell origin. Endoscopy. 46 Suppl 1 UCTN:E77–E78. 2014. View Article : Google Scholar : PubMed/NCBI

7 

Song Y, Huang Y, Hu Y and He C: Primary NK/T cell lymphoma of the esophagus: A case report. Chin J Oncol. 400:2014.(In Chinese).

8 

Tang J and Li D: Primary extranodal NK/T cell lymphoma, nasal type of the esophagus-gastric cardia: A case report. Chin J Diffic Compl Cas. 645–66. 2014.(In Chinese).

9 

Hosaka S, Nakamura N, Akamatsu T, Fujisawa T, Ogiwara Y, Kiyosawa K, Hidaka E, Ota H, Katsuyama T and Inagaki H: A case of primary low grade mucosa associated lymphoid tissue (MALT) lymphoma of the oesophagus. Gut. 51:281–284. 2002. View Article : Google Scholar : PubMed/NCBI

10 

Taal BG, Van Heerde P and Somers R: Isolated primary oesophageal involvement by lymphoma: A rare cause of dysphagia: Two case histories and a review of other published data. Gut. 34:994–998. 1993. View Article : Google Scholar : PubMed/NCBI

11 

Li JZ, Tao J, Ruan DY, Yang YD, Zhan YS, Wang X, Chen Y, Kuang SC, Shao CK and Wu B: Primary duodenal NK/T-cell lymphoma with massive bleeding: A case report. World J Clin Oncol. 3:92–97. 2012. View Article : Google Scholar : PubMed/NCBI

12 

Zheng S, Ouyang Q, Li G, Xu H, Jiang M, Cui D, Xue L and Li J: Primary intestinal NK/T cell lymphoma: A clinicopathologic study of 25 Chinese cases. Arch Iran Med. 15:36–42. 2012.PubMed/NCBI

13 

Bandyopadhyay SK, Moulick A and Dutta A: Primary duodenal lymphoma producing obstructive jaundice. J Assoc Physicians India. 55:76–77. 2007.PubMed/NCBI

14 

Coppens E, El Nakadi I, Nagy N and Zalcman M: Primary Hodgkin's lymphoma of the esophagus. AJR Am J Roentgenol. 180:1335–1337. 2003. View Article : Google Scholar : PubMed/NCBI

15 

Radin DR: Primary esophageal lymphoma in AIDS. Abdom Imaging. 18:223–224. 1993. View Article : Google Scholar : PubMed/NCBI

16 

Doki T, Hamada S, Murayama H, Suenaga H and Sannohe Y: Primary malignant lymphoma of the esophagus. A case report. Endoscopy. 16:189–192. 1984. View Article : Google Scholar : PubMed/NCBI

17 

Kalogeropoulos IV, Chalazonitis AN, Tsolaki S, Laspas F, Ptohis N, Neofytou I and Rontogianni D: A case of primary isolated non-Hodgkin's lymphoma of the esophagus in an immunocompetent patient. World J Gastroenterol. 15:1901–1903. 2009. View Article : Google Scholar : PubMed/NCBI

18 

Lin CC, Lai HW, Tsai MC, Chen TH, Tseng SW, Chang H and Chen TY: Extranodal marginal zone B-cell lymphoma of the gastrointestinal tract sparing only the esophagus: A case report. Turk J Gastroenterol. 23:58–62. 2012. View Article : Google Scholar : PubMed/NCBI

19 

Kurihara K, Fukui A and Kumano S: Malignant lymphoma of the esophagus associated with macroglobulinemia: Report of a case. Pathol Int. 44:712–715. 1994. View Article : Google Scholar : PubMed/NCBI

20 

Kim TM, Lee SY, Jeon YK, Ryoo BY, Cho GJ, Hong YS, Kim HJ, Kim SY, Kim CS, Kim S, et al: Clinical heterogeneity of extranodal NK/T-cell lymphoma, nasal type: A national survey of the Korean cancer study group. Ann Oncol. 19:1477–1484. 2008. View Article : Google Scholar : PubMed/NCBI

21 

Bautista-Quach MA, Ake CD, Chen M and Wang J: Gastrointestinal lymphomas: Morphology, immunophenotype and molecular features. J Gastrointest Oncol. 3:209–225. 2012.PubMed/NCBI

22 

Jaffe ES, Chan JK, Su IJ, Frizzera G, Mori S, Feller AC and Ho FC: Report of the workshop on nasal and related extranodal angiocentric T/Natural killer cell lymphomas. definitions, differential diagnosis and epidemiology. Am J Surg Pathol. 20:103–111. 1996. View Article : Google Scholar : PubMed/NCBI

23 

Crook TW and Robinson RA: Dysphagia in a patient with a history of large B-cell lymphoma: Esophageal disease with negative biopsy findings. Diagn Cytopathol. 26:167–169. 2002. View Article : Google Scholar : PubMed/NCBI

24 

Kim JH, Lee JH, Lee J, Oh SO, Chang DK, Rhee PL, Kim JJ, Rhee JC, Lee J, Kim WS and Ko YH: Primary NK-/T-cell lymphoma of the gastrointestinal tract: Clinical characteristics and endoscopic findings. Endoscopy. 39:156–160. 2007. View Article : Google Scholar : PubMed/NCBI

25 

Santra G: Oesophageal involvement in mantle cell lymphoma. Singapore Med J. 51:e201–e203. 2010.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Liang P, Ren XC and Gao JB: Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report. Oncol Lett 14: 2147-2152, 2017.
APA
Liang, P., Ren, X., & Gao, J. (2017). Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report. Oncology Letters, 14, 2147-2152. https://doi.org/10.3892/ol.2017.6456
MLA
Liang, P., Ren, X., Gao, J."Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report". Oncology Letters 14.2 (2017): 2147-2152.
Chicago
Liang, P., Ren, X., Gao, J."Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report". Oncology Letters 14, no. 2 (2017): 2147-2152. https://doi.org/10.3892/ol.2017.6456
Copy and paste a formatted citation
x
Spandidos Publications style
Liang P, Ren XC and Gao JB: Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report. Oncol Lett 14: 2147-2152, 2017.
APA
Liang, P., Ren, X., & Gao, J. (2017). Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report. Oncology Letters, 14, 2147-2152. https://doi.org/10.3892/ol.2017.6456
MLA
Liang, P., Ren, X., Gao, J."Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report". Oncology Letters 14.2 (2017): 2147-2152.
Chicago
Liang, P., Ren, X., Gao, J."Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report". Oncology Letters 14, no. 2 (2017): 2147-2152. https://doi.org/10.3892/ol.2017.6456
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team