|
1
|
McGuire S: World Cancer Report 2014.
Geneva, Switzerland: World Health Organization, International
Agency for Research on Cancer, WHO Press, 2015. Adv Nutr.
7:418–419. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Reck M, Popat S, Reinmuth N, De Ruysscher
D, Kerr KM and Peters S; ESMO Guidelines Working Group, :
Metastatic non-small-cell lung cancer (NSCLC): ESMO clinical
practice guidelines for diagnosis, treatment and follow-up. Ann
Oncol. 25 Suppl 3:iii27–iii39. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Herbst RS, Heymach JV and Lippman SM: Lung
cancer. N Engl J Med. 359:1367–1380. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Pao W, Miller VA, Politi KA, Riely GJ,
Somwar R, Zakowski MF, Kris MG and Varmus H: Acquired resistance of
lung adenocarcinomas to gefitinib or erlotinib is associated with a
second mutation in the EGFR kinase domain. PLoS Med. 2:e732005.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Newman DJ and Cragg GM: Natural products
as sources of new drugs over the last 25 years. J Nat Prod.
70:461–477. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Ai J, Gao HH, He SZ, Wang L, Luo DL and
Yang BF: Effects of matrine, artemisinin, tetrandrine on cytosolic
[Ca2+]i in guinea pig ventricular myocytes. Acta Pharmacol Sin.
22:512–515. 2001.PubMed/NCBI
|
|
7
|
Cheng H, Xia B, Zhang L, Zhou F, Zhang YX,
Ye M, Hu ZG, Li J, Li J, Wang ZL, et al: Matrine improves
2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice.
Pharmacol Res. 53:202–208. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Li X, Chu W, Liu J, Xue X, Lu Y, Shan H
and Yang B: Antiarrhythmic properties of long-term treatment with
matrine in arrhythmic rat induced by coronary ligation. Biol Pharm
Bull. 32:1521–1526. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Long Y, Lin XT, Zeng KL and Zhang L:
Efficacy of intramuscular matrine in the treatment of chronic
hepatitis B. Hepatobiliary Pancreat Dis Int. 3:69–72.
2004.PubMed/NCBI
|
|
10
|
Ma L, Wen S, Zhan Y, He Y, Liu X and Jiang
J: Anticancer effects of the Chinese medicine matrine on murine
hepatocellular carcinoma cells. Planta Med. 74:245–251. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Zhang P, Wang Z, Chong T and Ji Z: Matrine
inhibits proliferation and induces apoptosis of the
androgen-independent prostate cancer cell line PC-3. Mol Med Rep.
5:783–787. 2012.PubMed/NCBI
|
|
12
|
Zhang Y, Zhang H, Yu P, Liu Q, Liu K, Duan
H, Luan G, Yagasaki K and Zhang G: Effects of matrine against the
growth of human lung cancer and hepatoma cells as well as lung
cancer cell migration. Cytotechnology. 59:191–200. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Liu Y, Xu Y, Ji W, Li X, Sun B, Gao Q and
Su C: Anti-tumor activities of matrine and oxymatrine: Literature
review. Tumour Biol. 35:5111–5119. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Shao H, Yang B, Hu R and Wang Y: Matrine
effectively inhibits the proliferation of breast cancer cells
through a mechanism related to the NF-κB signaling pathway. Oncol
Lett. 6:517–520. 2013.PubMed/NCBI
|
|
15
|
Tan C, Qian X, Jia R, Wu M and Liang Z:
Matrine induction of reactive oxygen species activates p38 leading
to caspase-dependent cell apoptosis in non-small cell lung cancer
cells. Oncol Rep. 30:2529–2535. 2013.PubMed/NCBI
|
|
16
|
Niu H, Zhang Y, Wu B, Zhang Y, Jiang H and
He P: Matrine induces the apoptosis of lung cancer cells through
downregulation of inhibitor of apoptosis proteins and the Akt
signaling pathway. Oncol Rep. 32:1087–1093. 2014.PubMed/NCBI
|
|
17
|
Xiang J and Jiang Y: Antiepileptic
potential of matrine via regulation the levels of
gamma-aminobutyric acid and glutamic acid in the brain. Int J Mol
Sci. 14:23751–23761. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lu ZG, Li MH, Wang JS, Wei DD, Liu QW and
Kong LY: Developmental toxicity and neurotoxicity of two
matrine-type alkaloids, matrine and sophocarpine, in zebrafish
(Danio rerio) embryos/larvae. Reprod toxicol. 47:33–41. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Chao F, Wang DE, Liu R, Tu Q, Liu JJ and
Wang J: Synthesis, characterization and activity evaluation of
matrinic acid derivatives as potential antiproliferative agents.
Molecules. 18:5420–5433. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Du NN, Li X, Wang YP, Liu F, Liu YX, Li
CX, Peng ZG, Gao LM, Jiang JD and Song DQ: Synthesis,
structure-activity relationship and biological evaluation of novel
N-substituted matrinic acid derivatives as host heat-stress cognate
70 (Hsc70) down-regulators. Bioorg Med Chem Lett. 21:4732–4735.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Yong J, Wu X and Lu C: Anticancer advances
of matrine and its derivatives. Curr Pharm Des. 21:3673–3680. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wang L, You Y, Wang S, Liu X, Liu B, Wang
J, Lin X, Chen M, Liang G and Yang H: Synthesis, characterization
and in vitro anti-tumor activities of matrine derivatives. Bioorg
Med Chem Lett. 22:4100–4102. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Wu LC, Wen ZS, Qiu YT, Chen XQ, Chen HB,
Wei MM, Liu Z, Jiang S and Zhou GB: Largazole arrests cell cycle at
G1 phase and triggers proteasomal degradation of E2F1 in lung
cancer cells. Acs Med Chem Lett. 4:921–926. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Wu L, Guo L, Liang Y, Liu X, Jiang L and
Wang L: Curcumin suppresses stem-like traits of lung cancer cells
via inhibiting the JAK2/STAT3 signaling pathway. Oncol Rep.
34:3311–3317. 2015.PubMed/NCBI
|
|
25
|
Weinberg RA: The retinoblastoma protein
and cell cycle control. Cell. 81:323–330. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Padilla F, Bhagirath N, Chen S, Chiao E,
Goldstein DM, Hermann JC, Hsu J, Kennedy-Smith JJ, Kuglstatter A,
Liao C, et al: Pyrrolopyrazines as selective spleen tyrosine kinase
inhibitors. J Med Chem. 56:1677–1692. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Meng F, Qian J, Yue H, Li X and Xue K:
SUMOylation of Rb enhances its binding with CDK2 and
phosphorylation at early G1 phase. Cell Cycle. 15:1724–1732. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Gupta SC, Hevia D, Patchva S, Park B, Koh
W and Aggarwal BB: Upsides and downsides of reactive oxygen species
for cancer: The roles of reactive oxygen species in tumorigenesis,
prevention, and therapy. Antioxid Redox Signal. 16:1295–1322. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Ozben T: Oxidative stress and apoptosis:
Impact on cancer therapy. J Pharm Sci. 96:2181–2196. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Conklin KA: Chemotherapy-associated
oxidative stress: Impact on chemotherapeutic effectiveness. Integr
Cancer Ther. 3:294–300. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Circu ML and Aw TY: Reactive oxygen
species, cellular redox systems and apoptosis. Free Radic Biol Med.
48:749–762. 2010. View Article : Google Scholar : PubMed/NCBI
|
