1
|
Siegel R, Desantis C and Jemal A:
Colorectal cancer statistics, 2014. CA Cancer J Clin. 64:104–117.
2014. View Article : Google Scholar : PubMed/NCBI
|
2
|
DeBerardinis RJ, Lum JJ, Hatzivassiliou G
and Thompson CB: The biology of cancer: Metabolic reprogramming
fuels cell growth and proliferation. Cell Metab. 7:11–20. 2008.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Dang CV: Links between metabolism and
cancer. Genes Dev. 26:877–890. 2012. View Article : Google Scholar : PubMed/NCBI
|
4
|
Vander Heiden MG, Cantley LC and Thompson
CB: Understanding the Warburg effect: The metabolic requirements of
cell proliferation. Science. 324:1029–1033. 2009. View Article : Google Scholar : PubMed/NCBI
|
5
|
Cairns RA, Harris IS and Mak TW:
Regulation of cancer cell metabolism. Nat Rev Cancer. 11:85–95.
2011. View
Article : Google Scholar : PubMed/NCBI
|
6
|
Wise DR and Thompson CB: Glutamine
addiction: A new therapeutic target in cancer. Trends Biochem Sci.
35:427–433. 2010. View Article : Google Scholar : PubMed/NCBI
|
7
|
Daye D and Wellen KE: Metabolic
reprogramming in cancer: Unraveling the role of glutamine in
tumorigenesis. Semin Cell Dev Biol. 23:362–369. 2012. View Article : Google Scholar : PubMed/NCBI
|
8
|
Hensley CT, Wasti AT and DeBerardinis RJ:
Glutamine and cancer: Cell biology, physiology, and clinical
opportunities. J Clin Invest. 123:3678–3684. 2013. View Article : Google Scholar : PubMed/NCBI
|
9
|
Curthoys NP and Watford M: Regulation of
glutaminase activity and glutamine metabolism. Annu Rev Nutr.
15:133–159. 1995. View Article : Google Scholar : PubMed/NCBI
|
10
|
Mates JM, Segura JA, Martín-Rufian M,
Campos-Sandoval JA, Alonso FJ and Márquez J: Glutaminase isoenzymes
as key regulators in metabolic and oxidative stress against cancer.
Curr Mol Med. 13:514–534. 2013. View Article : Google Scholar : PubMed/NCBI
|
11
|
Huang F, Zhang Q, Ma H, Lv Q and Zhang T:
Expression of glutaminase is upregulated in colorectal cancer and
of clinical significance. Int J Clin Exp Pathol. 7:1093–1100.
2014.PubMed/NCBI
|
12
|
Pan T, Gao L, Wu G, Shen G, Xie S, Wen H,
Yang J, Zhou Y, Tu Z and Qian W: Elevated expression of glutaminase
confers glucose utilization via glutaminolysis in prostate cancer.
Biochem Biophys Res Commun. 456:452–458. 2015. View Article : Google Scholar : PubMed/NCBI
|
13
|
Gross MI, Demo SD, Dennison JB, Chen L,
Chernov-Rogan T, Goyal B, Janes JR, Laidig GJ, Lewis ER, Li J, et
al: Antitumor activity of the glutaminase inhibitor CB-839 in
triple-negative breast cancer. Mol Cancer Ther. 13:890–901. 2014.
View Article : Google Scholar : PubMed/NCBI
|
14
|
Kaadige MR, Elgort MG and Ayer DE:
Coordination of glucose and glutamine utilization by an expanded
Myc network. Transcription. 1:36–40. 2010. View Article : Google Scholar : PubMed/NCBI
|
15
|
Gao P, Tchernyshyov I, Chang TC, Lee YS,
Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT and
Dang CV: c-Myc suppression of miR-23a/b enhances mitochondrial
glutaminase expression and glutamine metabolism. Nature.
458:762–765. 2009. View Article : Google Scholar : PubMed/NCBI
|
16
|
Tanaka K, Sasayama T, Irino Y, Takata K,
Nagashima H, Satoh N, Kyotani K, Mizowaki T, Imahori T, Ejima Y, et
al: Compensatory glutamine metabolism promotes glioblastoma
resistance to mTOR inhibitor treatment. J Clin Invest.
125:1591–1602. 2015. View
Article : Google Scholar : PubMed/NCBI
|
17
|
Carr EL, Kelman A, Wu GS, Gopaul R,
Senkevitch E, Aghvanyan A, Turay AM and Frauwirth KA: Glutamine
uptake and metabolism are coordinately regulated by ERK/MAPK during
T lymphocyte activation. J Immunol. 185:1037–1044. 2010. View Article : Google Scholar : PubMed/NCBI
|
18
|
Robinson MM, McBryant SJ, Tsukamoto T,
Rojas C, Ferraris DV, Hamilton SK, Hansen JC and Curthoys NP: Novel
mechanism of inhibition of rat kidney-type glutaminase by
bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide
(BPTES). Biochem J. 406:407–414. 2007. View Article : Google Scholar : PubMed/NCBI
|
19
|
Stalnecker CA, Ulrich SM, Li Y,
Ramachandran S, McBrayer MK, DeBerardinis RJ, Cerione RA and
Erickson JW: Mechanism by which a recently discovered allosteric
inhibitor blocks glutamine metabolism in transformed cells. Proc
Natl Acad Sci USA. 112:394–399. 2015. View Article : Google Scholar : PubMed/NCBI
|
20
|
Williams DM, Schachter J, Drutz DJ and
Sumaya CV: Pneumonia due to Chlamydia trachomatis in the
immunocompromised (nude) mouse. J Infect Dis. 143:238–241. 1981.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Chu D, Zhang Z, Li Y, Wu L and Zhang J,
Wang W and Zhang J: Prediction of colorectal cancer relapse and
prognosis by tissue mRNA levels of NDRG2. Mol Cancer Ther.
10:47–56. 2011. View Article : Google Scholar : PubMed/NCBI
|
22
|
Kaadige MR, Looper RE, Kamalanaadhan S and
Ayer DE: Glutamine-dependent anapleurosis dictates glucose uptake
and cell growth by regulating MondoA transcriptional activity. Proc
Natl Acad Sci USA. 106:14878–14883. 2009. View Article : Google Scholar : PubMed/NCBI
|
23
|
Tennant DA, Durán RV and Gottlieb E:
Targeting metabolic transformation for cancer therapy. Nat Rev
Cancer. 10:267–277. 2010. View
Article : Google Scholar : PubMed/NCBI
|
24
|
Richard SM and Martinez Marignac VL:
Sensitization to oxaliplatin in HCT116 and HT29 cell lines by
metformin and ribavirin and differences in response to
mitochondrial glutaminase inhibition. J Cancer Res Ther.
11:336–340. 2015. View Article : Google Scholar : PubMed/NCBI
|