Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
October-2017 Volume 14 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October-2017 Volume 14 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

A comparative study on the efficacy of fast-track surgery in the treatment of esophageal cancer patients combined with metabolic syndrome

  • Authors:
    • Ziteng Zhang
    • Haijun Li
    • Chunzhang Yan
    • Baobin Xu
    • Ronghang Hu
    • Ming Ma
    • Haixiang Wei
    • Yanhong Meng
  • View Affiliations / Copyright

    Affiliations: Department of Thoracic Surgery, Affiliated Hospital of Jining Medical University, Jining, Shandong 272000, P.R. China, Department of Emergency, Affiliated Hospital of Jining Medical University, Jining, Shandong 272000, P.R. China, Department of Thoracic Surgery, Wenshang People's Hospital, Wenshang, Shandong 272500, P.R. China, Department of Ultrasonography, Affiliated Hospital of Jining Medical University, Jining, Shandong 272000, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 4812-4816
    |
    Published online on: August 17, 2017
       https://doi.org/10.3892/ol.2017.6759
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The purpose of our study was to evaluate the clinical efficacy of fast-track surgery (FTS) in the treatment of esophageal cancer patients combined with metabolic syndrome. Ninety-four esophageal cancer patients with metabolic syndrome were selected in Affiliated Hospital of Jining Medical University from March, 2016 to February, 2017. Patients were randomly divided into control group and observation group with 47 cases in each group. Patients in observation group were treated with FTS, while patients in control group were treated with traditional method. Intraoperative blood loss, the number of dissected lymph nodes, operation time, postoperative hospital stay, the cost of hospitalization, postoperative readmission rate, and incidence of postoperative complications were compared between the groups. Levels of serum inflammatory cytokines (TNF-α and hs-CRP), fat cell factor chemerin and leptin (LP) were detected by enzyme-linked immunosorbent assay (ELISA) at 1 month after surgery. Levels of serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) at 1 month after surgery were compared between groups. Levels of hemoglobin (Hb), albumin (Alb), prealbumin (PAB) and transferrin (TRF) at 1 month after surgery were also compared between the two groups. Treatment of cancer quality-of-life questionnaire-esophageal cancer (OES‑18) module was used to evaluate the symptoms of patients at one month after surgery. It turned out that no significant differences in intraoperative blood loss, operation time and the number of dissected lymph nodes were found between groups (p>0.05). Postoperative hospital stay, the cost of hospitalization, postoperative readmission rate and the incidence of postoperative complications were significantly lower in observation group than in control group (p<0.05). Levels of TNF-α, hs-CRP, chemerin and LP in observation group were significantly lower than those in control group at one month after surgery (p<0.05). Levels of TC, TG and LDL-C were significantly lower and HDL-C level was significantly higher in observation group than in control group at one month after surgery (p<0.05). Levels of Hb and Alb were significantly lower and levels of PAB and TRF were significantly higher in observation group than in control group at one month after surgery (p<0.05). OES-18 score of observation group was significantly better than that of control group at one month after surgery (p<0.05). As a conclusion, FTS can promote postoperative rehabilitation, shorten hospital stay, reduce economic burden and reduce the rehospitalization rate of esophageal cancer patients. At the same time, FTS can also improve the lipid metabolism, nutritional status and regulate the differentiation of adipocytes, alleviate the low inflammatory response state, which in turn promotes metabolic syndrome.
View Figures
View References

1 

Probst A, Aust D, Märkl B, Anthuber M and Messmann H: Early esophageal cancer in Europe: Endoscopic treatment by endoscopic submucosal dissection. Endoscopy. 47:113–121. 2015.PubMed/NCBI

2 

Oyama T: Endoscopic submucosal dissection for superficial esophageal cancer. Gastrointest Endosc. 65:AB110. 2015.

3 

van der Sluis PC, Ruurda JP, Verhage RJ, van der Horst S, Haverkamp L, Siersema PD, Rinkes Borel IH, Kate Ten FJ and van Hillegersberg R: Oncologic long-term results of robot-assisted minimally invasive thoraco-laparoscopic esophagectomy with two-field lymphadenectomy for esophageal cancer. Ann Surg Oncol. 22 Suppl 3:S1350–S1356. 2015. View Article : Google Scholar : PubMed/NCBI

4 

Shah MA: Update on metastatic gastric and esophageal cancers. J Clin Oncol. 33:1760–1769. 2015. View Article : Google Scholar : PubMed/NCBI

5 

Bonomini F, Rodella LF and Rezzani R: Metabolic syndrome, aging and involvement of oxidative stress. Aging Dis. 6:109–120. 2015. View Article : Google Scholar : PubMed/NCBI

6 

Bu J, Li N, Huang X, He S, Wen J and Wu X: Feasibility of fast-track surgery in elderly patients with gastric cancer. J Gastrointest Surg. 19:1391–1398. 2015. View Article : Google Scholar : PubMed/NCBI

7 

Forootan M, Tabatabaeefar M, Maghsoodi N, Ardeshiri M, Fatemi M and Rahimzadeh H: Adaptation of a quality of life questionnaire for Iranian patients with esophageal cancer. Indian J Palliat Care. 20:123–127. 2014. View Article : Google Scholar : PubMed/NCBI

8 

Xu W, Liu Z, Bao Q and Qian Z: Viruses, other pathogenic microorganisms and esophageal cancer. Gastrointest Tumors. 2:2–13. 2015. View Article : Google Scholar : PubMed/NCBI

9 

Mirinezhad SK, Somi MH, Jangjoo AG, Seyednezhad F, Dastgiri S, Mohammadzadeh M, Naseri AR and Nasiri B: Survival rate and prognostic factors of esophageal cancer in east Azerbaijan province, North-west of Iran. Asian Pac J Cancer Prev. 13:3451–3454. 2012. View Article : Google Scholar : PubMed/NCBI

10 

Kinjo Y, Kurita N, Nakamura F, Okabe H, Tanaka E, Kataoka Y, Itami A, Sakai Y and Fukuhara S: Effectiveness of combined thoracoscopic-laparoscopic esophagectomy: Comparison of postoperative complications and midterm oncological outcomes in patients with esophageal cancer. Surg Endosc. 26:381–390. 2012. View Article : Google Scholar : PubMed/NCBI

11 

Kutup A, Nentwich MF, Bollschweiler E, Bogoevski D, Izbicki JR and Hölscher AH: What should be the gold standard for the surgical component in the treatment of locally advanced esophageal cancer: Transthoracic versus transhiatal esophagectomy. Ann Surg. 260:1016–1022. 2014. View Article : Google Scholar : PubMed/NCBI

12 

Zhang SW, Zheng RS, Zuo TT, Zeng HM, Chen WQ and He J: Mortality and survival analysis of esophageal cancer in China. Zhonghua Zhong Liu Za Zhi. 38:709–715. 2016.(In Chinese). PubMed/NCBI

13 

Dumans-Nizard V, Guezennec J, Parquin F, Puyo P, Sage E, Abdat R, Vaillant V, Chapelier A, Dreyfus JF, Fischler M, et al: Foch Thoracic Anesthesiology Group: Feasibility and results of a fast-track protocol in thoracic surgery. Minerva Anestesiol. 82:15–21. 2016.PubMed/NCBI

14 

Bu J and Wu X: Reply to the letter to the editor regarding manuscript entitled: ‘Feasibility of fast-track surgery in gastrectomy for elderly patients with gastric cancer’. J Gastrointest Surg. 19:2294–2295. 2015. View Article : Google Scholar : PubMed/NCBI

15 

Lonardo A, Ballestri S, Marchesini G, Angulo P and Loria P: Nonalcoholic fatty liver disease: A precursor of the metabolic syndrome. Dig Liver Dis. 47:181–190. 2015. View Article : Google Scholar : PubMed/NCBI

16 

Tang L, Okamoto S, Shiuchi T, Toda C, Takagi K, Sato T, Saito K, Yokota S and Minokoshi Y: Sympathetic nerve activity maintains an anti-inflammatory state in adipose tissue in male mice by inhibiting TNF-α gene expression in macrophages. Endocrinology. 156:3680–3694. 2015. View Article : Google Scholar : PubMed/NCBI

17 

Tawfik PH, Hafez SS, Mahmoud NH and Sayed HME: Serum Fetuin A, hs-CRP and homocysteine as biochemical markers of cardiovascular complications in chronic dialysis patients. Acta Med Int. 2:57–64. 2015. View Article : Google Scholar

18 

Johnson AM, Kurti SP, Smith JR, Rosenkranz SK and Harms CA: Effects of an acute bout of moderate-intensity exercise on postprandial lipemia and airway inflammation. Appl Physiol Nutr Metab. 41:284–291. 2016. View Article : Google Scholar : PubMed/NCBI

19 

Bobbert T, Schwarz F, Fischer-Rosinsky A, Maurer L, Möhlig M, Pfeiffer AF, Mai K and Spranger J: Chemerin and prediction of Diabetes mellitus type 2. Clin Endocrinol (Oxf). 82:838–843. 2015. View Article : Google Scholar : PubMed/NCBI

20 

Dodd GT, Decherf S, Loh K, Simonds SE, Wiede F, Balland E, Merry TL, Münzberg H, Zhang ZY, Kahn BB, et al: Leptin and insulin act on POMC neurons to promote the browning of white fat. Cell. 160:88–104. 2015. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhang Z, Li H, Yan C, Xu B, Hu R, Ma M, Wei H and Meng Y: A comparative study on the efficacy of fast-track surgery in the treatment of esophageal cancer patients combined with metabolic syndrome. Oncol Lett 14: 4812-4816, 2017.
APA
Zhang, Z., Li, H., Yan, C., Xu, B., Hu, R., Ma, M. ... Meng, Y. (2017). A comparative study on the efficacy of fast-track surgery in the treatment of esophageal cancer patients combined with metabolic syndrome. Oncology Letters, 14, 4812-4816. https://doi.org/10.3892/ol.2017.6759
MLA
Zhang, Z., Li, H., Yan, C., Xu, B., Hu, R., Ma, M., Wei, H., Meng, Y."A comparative study on the efficacy of fast-track surgery in the treatment of esophageal cancer patients combined with metabolic syndrome". Oncology Letters 14.4 (2017): 4812-4816.
Chicago
Zhang, Z., Li, H., Yan, C., Xu, B., Hu, R., Ma, M., Wei, H., Meng, Y."A comparative study on the efficacy of fast-track surgery in the treatment of esophageal cancer patients combined with metabolic syndrome". Oncology Letters 14, no. 4 (2017): 4812-4816. https://doi.org/10.3892/ol.2017.6759
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang Z, Li H, Yan C, Xu B, Hu R, Ma M, Wei H and Meng Y: A comparative study on the efficacy of fast-track surgery in the treatment of esophageal cancer patients combined with metabolic syndrome. Oncol Lett 14: 4812-4816, 2017.
APA
Zhang, Z., Li, H., Yan, C., Xu, B., Hu, R., Ma, M. ... Meng, Y. (2017). A comparative study on the efficacy of fast-track surgery in the treatment of esophageal cancer patients combined with metabolic syndrome. Oncology Letters, 14, 4812-4816. https://doi.org/10.3892/ol.2017.6759
MLA
Zhang, Z., Li, H., Yan, C., Xu, B., Hu, R., Ma, M., Wei, H., Meng, Y."A comparative study on the efficacy of fast-track surgery in the treatment of esophageal cancer patients combined with metabolic syndrome". Oncology Letters 14.4 (2017): 4812-4816.
Chicago
Zhang, Z., Li, H., Yan, C., Xu, B., Hu, R., Ma, M., Wei, H., Meng, Y."A comparative study on the efficacy of fast-track surgery in the treatment of esophageal cancer patients combined with metabolic syndrome". Oncology Letters 14, no. 4 (2017): 4812-4816. https://doi.org/10.3892/ol.2017.6759
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team