|
1
|
Lin W and Karin M: A cytokine-mediated
link between innate immunity, inflammation, and cancer. J Clin
Invest. 117:1175–1183. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
2
|
Visvader JE and Lindeman GJ: Cancer stem
cells: Current status and evolving complexities. Cell Stem Cell.
10:717–728. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Wright MH, Calcagno AM, Salcido CD,
Carlson MD, Ambudkar SV and Varticovski L: Brca1 breast tumors
contain distinct CD44+/CD24- and CD133+ cells with cancer stem cell
characteristics. Breast Cancer Res. 10:R102008. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Sahlberg SH, Spiegelberg D, Glimelius B,
Stenerlöw B and Nestor M: Evaluation of cancer stem cell markers
CD133, CD44, CD24: Association with AKT isoforms and radiation
resistance in colon cancer cells. PLoS One. 9:e946212014.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Monzani E, Facchetti F, Galmozzi E,
Corsini E, Benetti A, Cavazzin C, Gritti A, Piccinini A, Porro D,
Santinami M, et al: Melanoma contains CD133 and ABCG2 positive
cells with enhanced tumourigenic potential. Eur J Cancer.
43:935–946. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Kryczek I, Liu S, Roh M, Vatan L, Szeliga
W, Wei S, Banerjee M, Mao Y, Kotarski J, Wicha MS, et al:
Expression of aldehyde dehydrogenase and CD133 defines ovarian
cancer stem cells. Int J Cancer. 130:29–39. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Molejon MI, Tellechea JI, Loncle C, Gayet
O, Duconseil P, Lopez-millan MB, Moutardier V, Gasmi M, Garcia S,
Turrini O, et al: Deciphering the cellular source of tumor relapse
identifies CD44 as a major therapeutic target in pancreatic
adenocarcinoma. Oncotarget. 6:7408–7423. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Zöller M: CD44: Can a cancer-initiating
cell profit from an abundantly expressed molecule? Nat Rev Cancer.
11:254–267. 2011. View
Article : Google Scholar : PubMed/NCBI
|
|
9
|
Jijiwa M, Demir H, Gupta S, Leung C, Joshi
K, Orozco N, Huang T, Yildiz VO, Shibahara I, de Jesus JA, et al:
CD44v6 regulates growth of brain tumor stem cells partially through
the AKT-mediated pathway. PLoS One. 6:e242172011. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Todaro M, Gaggianesi M, Catalano V,
Benfante A, Iovino F, Biffoni M, Apuzzo T, Sperduti I, Volpe S,
Cocorullo G, et al: CD44v6 is a marker of constitutive and
reprogrammed cancer stem cells driving colon cancer metastasis.
Cell Stem Cell. 14:342–356. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Rall CJ and Rustgi AK: CD44 isoform
expression in primary and metastatic pancreatic adenocarcinoma.
Cancer Res. 55:1831–1835. 1995.PubMed/NCBI
|
|
12
|
Liu G, Yuan X, Zeng Z, Benfante A, Iovino
F, Biffoni M, Apuzzo T, Sperduti I, Volpe S and Cocorullo G:
Analysis of gene expression and chemoresistance of CD133+ cancer
stem cells in glioblastoma. Mol Cancer. 5:672006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Zhang Q, Shi S, Yen Y, Brown J, Ta JQ and
Le AD: A subpopulation of CD133+ cancer stem-like cells
characterized in human oral squamous cell carcinoma confer
resistance to chemotherapy. Cancer Lett. 289:151–160. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Hermann PC, Huber SL, Herrler T, Aicher A,
Ellwart JW, Guba M, Bruns CJ and Heeschen C: Distinct populations
of cancer stem cells determine tumor growth and metastatic activity
in human pancreatic cancer. Cell Stem Cell. 1:313–323. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Maeda S, Shinchi H, Kurahara H, Mataki Y,
Maemura K, Sato M, Natsugoe S, Aikou T and Takao S: CD133
expression is correlated with lymph node metastasis and vascular
endothelial growth factor-C expression in pancreatic cancer. Br J
Cancer. 98:1389–1397. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
An Y and Ongkeko WM: ABCG2: The key to
chemoresistance in cancer stem cells? Expert Opin Drug Metab
Toxicol. 5:1529–1542. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Ikushima H and Miyazono K: TGFbeta
signalling: A complex web in cancer progression. Nat Rev Cancer.
10:415–424. 2010. View
Article : Google Scholar : PubMed/NCBI
|
|
18
|
Balkwill F: TNF-α in promotion and
progression of cancer. Cancer Metastasis Rev. 25:409–416. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Egberts JH, Cloosters V, Noack A,
Schniewind B, Thon L, Klose S, Kettler B, von Forstner C, Kneitz C,
Tepel J, et al: Anti-tumor necrosis factor therapy inhibits
pancreatic tumor growth and metastasis. Cancer Res. 68:1443–1450.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Roshani R, McCarthy F and Hagemann T:
Inflammatory cytokines in human pancreatic cancer. Cancer Lett.
345:157–163. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Lin Y, Kikuchi S, Tamakoshi A, Obata Y,
Yagyu K, Inaba Y, Kurosawa M, Kawamura T, Motohashi Y and Ishibashi
T: JACC Study Group: Serum transforming growth factor-beta1 levels
and pancreatic cancer risk: A nested case-control study (Japan).
Cancer Causes Control. 17:1077–1082. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Poch B, Lotspeich E, Ramadani M, Gansauge
S, Beger HG and Gansauge F: Systemic immune dysfunction in
pancreatic cancer patients. Langenbecks Arch Surg. 392:353–358.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ikushima H, Todo T, Ino Y, Takahashi M,
Miyazawa K and Miyazono K: Autocrine TGF-beta signaling maintains
tumorigenicity of glioma-initiating cells through Sry-related
HMG-box factors. Cell Stem Cell. 5:504–514. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kagoya Y, Yoshimi A, Kataoka K, Nakagawa
M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y and Kurokawa
M: Positive feedback between NF-κB and TNF-α promotes
leukemia-initiating cell capacity. J Clin Invest. 124:528–542.
2014. View
Article : Google Scholar : PubMed/NCBI
|
|
25
|
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan
A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, et al: The
epithelial-mesenchymal transition generates cells with properties
of stem cells. Cell. 133:704–715. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ho MY, Tang SJ, Chuang MJ, Cha TL, Li JY,
Sun GH and Sun KH: TNF-α induces epithelial-mesenchymal transition
of renal cell carcinoma cells via a GSK3β-dependent mechanism. Mol
Cancer Res. 10:1109–1119. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Borthwick LA, Gardner A, De Soyza A, Mann
DA and Fisher AJ: Transforming growth factor-β1 (TGF-β1) driven
epithelial to mesenchymal transition (EMT) is accentuated by tumour
necrosis factor α (TNFα) via crosstalk between the SMAD and NF-κB
pathways. Cancer Microenviron. 5:45–57. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Schmiegel W, Roeder C, Schmielau J, Rodeck
U and Kalthoff H: Tumor necrosis factor alpha induces the
expression of transforming growth factor alpha and the epidermal
growth factor receptor in human pancreatic cancer cells. Proc Natl
Acad Sci USA. 90:863–867. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Wey JS, Fan F, Gray MJ, Bauer TW, McCarty
MF, Somcio R, Liu W, Evans DB, Wu Y, Hicklin DJ and Ellis LM:
Vascular endothelial growth factor receptor-1 promotes migration
and invasion in pancreatic carcinoma cell lines. Cancer.
104:427–438. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Bao B, Azmi AS, Aboukameel A, Ahmad A,
Bolling-Fischer A, Sethi S, Ali S, Li Y, Kong D, Banerjee S, et al:
Pancreatic cancer stem-like cells display aggressive behavior
mediated via activation of FoxQ1. J Biol Chem. 289:14520–14533.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Olempska M, Eisenach PA, Ammerpohl O,
Ungefroren H, Fandrich F and Kalthoff H: Detection of tumor stem
cell markers in pancreatic carcinoma cell lines. Hepatobiliary
Pancreat Dis Int. 6:92–97. 2007.PubMed/NCBI
|
|
32
|
Nomura A, Banerjee S, Chugh R, Dudeja V,
Yamamoto M, Vickers SM and Saluja AK: CD133 initiates tumors,
induces epithelial-mesenchymal transition and increases metastasis
in pancreatic cancer. Oncotarget. 6:8313–8322. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Wang Y, Yu Y, Tsuyada A, Ren X, Wu X,
Stubblefield K, Rankin-Gee EK and Wang SE: Transforming growth
factor-β regulates the sphere-initiating stem cell-like feature in
breast cancer through miRNA-181 and ATM. Oncogene. 30:1470–1480.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wang H, Wu J, Zhang Y, Xue X, Tang D, Yuan
Z, Chen M, Wei J, Zhang J and Miao Y: Transforming growth factor
beta-induced epithelial-mesenchymal transition increases cancer
stem-like cells in the PANC-1 cell line. Oncol Lett. 3:229–233.
2012.PubMed/NCBI
|
|
35
|
Asiedu MK, Ingle JN, Behrens MD, Radisky
DC and Knutson KL: TGFβ/TNF(alpha)-mediated epithelial-mesenchymal
transition generates breast cancer stem cells with a claudin-low
phenotype. Cancer Res. 71:4707–4719. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Eberl M, Klingler S, Mangelberger D,
Loipetzberger A, Damhofer H, Zoidl K, Schnidar H, Hache H, Bauer
HC, Solca F, et al: Hedgehog-EGFR cooperation response genes
determine the oncogenic phenotype of basal cell carcinoma and
tumour-initiating pancreatic cancer cells. EMBO Mol Med. 4:218–233.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Arumugam T, Ramachandran V, Fournier KF,
Wang H, Marquis L, Abbruzzese JL, Gallick GE, Logsdon CD, McConkey
DJ and Choi W: Epithelial to mesenchymal transition contributes to
drug resistance in pancreatic cancer. Cancer Res. 69:5820–5828.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Grivennikov SI and Karin M: Dangerous
liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer.
Cytokine Growth Factor Rev. 21:11–19. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Sun L, Mathews LA, Cabarcas SM, Zhang X,
Yang A, Zhang Y, Young MR, Klarmann KD, Keller JR and Farrar WL:
Epigenetic regulation of SOX9 by the NF-κB signaling pathway in
pancreatic cancer stem cells. Stem Cells. 31:1454–1466. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Lin L, Jou D, Wang Y, Ma H, Liu T, Fuchs
J, Li PK, Lü J, Li C and Lin J: STAT3 as a potential therapeutic
target in ALDH+ and CD44+/CD24+ stem cell-like pancreatic cancer
cells. Int J Oncol. 49:2265–2274. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Chow JY, Ban M, Wu HL, Nguyen F, Huang M,
Chung H, Dong H and Carethers JM: TGF-beta downregulates PTEN via
activation of NF-kappaB in pancreatic cancer cells. Am J Physiol
Gastrointest Liver Physiol. 298:G275–G282. 2010. View Article : Google Scholar : PubMed/NCBI
|
