1
|
Ferlay J, Shin HR, Bray F, Forman D,
Mathers C and Parkin DM: Estimates of worldwide burden of cancer in
2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar : PubMed/NCBI
|
2
|
Mullen JT and Ryan DP: Neoadjuvant
chemotherapy for gastric cancer: What are we trying to accomplish?
Ann Surg Oncol. 21:13–15. 2014. View Article : Google Scholar : PubMed/NCBI
|
3
|
Waddell T, Verheij M, Allum W, Cunningham
D, Cervantes A and Arnold D: European Society for Medical Oncology
(ESMO); European Society of Surgical Oncology (ESSO); European
Society of Radiotherapy and Oncology (ESTRO): Gastric cancer:
ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis,
treatment and follow-up. Eur J Surg Oncol. 40:584–591. 2014.
View Article : Google Scholar : PubMed/NCBI
|
4
|
Bogenrieder T and Herlyn M: Axis of evil:
Molecular mechanisms of cancer metastasis. Oncogene. 22:6524–6536.
2003. View Article : Google Scholar : PubMed/NCBI
|
5
|
Pearson JC, Lemons D and McGinnis W:
Modulating Hox gene functions during animal body patterning. Nat
Rev Genet. 6:893–904. 2005. View
Article : Google Scholar : PubMed/NCBI
|
6
|
Samuel S and Naora H: Homeobox gene
expression in cancer: Insights from developmental regulation and
deregulation. Eur J Cancer. 41:2428–2437. 2005. View Article : Google Scholar : PubMed/NCBI
|
7
|
Krumlauf R: Hox genes in vertebrate
development. Cell. 78:191–201. 1994. View Article : Google Scholar : PubMed/NCBI
|
8
|
Rauch T, Wang Z, Zhang X, Zhong X, Wu X,
Lau SK, Kernstine KH, Riggs AD and Pfeifer GP: Homeobox gene
methylation in lung cancer studied by genome-wide analysis with a
microarray-based methylated CpG island recovery assay. Proc Natl
Acad Sci USA. 104:5527–5532. 2007. View Article : Google Scholar : PubMed/NCBI
|
9
|
Cheng W, Liu J, Yoshida H, Rosen D and
Naora H: Lineage infidelity of epithelial ovarian cancers is
controlled by HOX genes that specify regional identity in the
reproductive tract. Nat Med. 11:531–537. 2005. View Article : Google Scholar : PubMed/NCBI
|
10
|
Vitiello D, Kodaman PH and Taylor HS: HOX
genes in implantation. Semin Reprod Med. 25:431–436. 2007.
View Article : Google Scholar : PubMed/NCBI
|
11
|
Shah N and Sukumar S: The Hox genes and
their roles in oncogenesis. Nat Rev Cancer. 10:361–371. 2010.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Gilbert PM, Mouw JK, Unger MA, Lakins JN,
Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KK,
et al: HOXA9 regulates BRCA1 expression to modulate human breast
tumor phenotype. J Clin Invest. 120:1535–1550. 2010. View Article : Google Scholar : PubMed/NCBI
|
13
|
Uchida K, Veeramachaneni R, Huey B,
Bhattacharya A, Schmidt BL and Albertson DG: Investigation of HOXA9
promoter methylation as a biomarker to distinguish oral cancer
patients at low risk of neck metastasis. BMC Cancer. 14:3532014.
View Article : Google Scholar : PubMed/NCBI
|
14
|
Guerrero-Preston R, Soudry E, Acero J,
Orera M, Moreno-López L, Macía-Colón G, Jaffe A, Berdasco M,
Ili-Gangas C, Brebi-Mieville P, et al: NID2 and HOXA9 promoter
hypermethylation as biomarkers for prevention and early detection
in oral cavity squamous cell carcinoma tissues and saliva. Cancer
Prev Res (Phila). 4:1061–1072. 2011. View Article : Google Scholar : PubMed/NCBI
|
15
|
Reynolds PA, Sigaroudinia M, Zardo G,
Wilson MB, Benton GM, Miller CJ, Hong C, Fridlyand J, Costello JF
and Tlsty TD: Tumor suppressor p16INK4A regulates polycomb-mediated
DNA hypermethylation in human mammary epithelial cells. J Biol
Chem. 281:24790–24802. 2006. View Article : Google Scholar : PubMed/NCBI
|
16
|
Sun M, Song CX, Huang H, Frankenberger CA,
Sankarasharma D, Gomes S, Chen P, Chen J, Chada KK, He C and Rosner
MR: HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer
growth and metastasis. Proc Natl Acad Sci USA. 110:9920–9925. 2013.
View Article : Google Scholar : PubMed/NCBI
|
17
|
Son JW, Jeong KJ, Jean WS, Park SY, Jheon
S, Cho HM, Park CG, Lee HY and Kang J: Genome-wide combination
profiling of DNA copy number and methylation for deciphering
biomarkers in non-small cell lung cancer patients. Cancer Lett.
311:29–37. 2011. View Article : Google Scholar : PubMed/NCBI
|
18
|
Wu Q, Lothe RA, Ahlquist T, Silins I,
Tropé CG, Micci F, Nesland JM, Suo Z and Lind GE: DNA methylation
profiling of ovarian carcinomas and their in vitro models
identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets. Mol
Cancer. 6:452007. View Article : Google Scholar : PubMed/NCBI
|
19
|
Reinert T, Borre M, Christiansen A,
Hermann GG, Ørntoft TF and Dyrskjot L: Diagnosis of bladder cancer
recurrence based on urinary levels of EOMES, HOXA9, POU4F2, TWIST1,
VIM and ZNF154 hypermethylation. PLoS One. 7:e462972012. View Article : Google Scholar : PubMed/NCBI
|
20
|
Ko SY, Barengo N, Ladanyi A, Lee JS,
Marini F, Lengyel E and Naora H: HOXA9 promotes ovarian cancer
growth by stimulating cancer-associated fibroblasts. J Clin Invest.
122:3603–3617. 2012. View
Article : Google Scholar : PubMed/NCBI
|
21
|
Chang CP, Brocchieri L, Shen WF, Largman C
and Cleary ML: Pbx modulation of Hox homeodomain amino-terminal
arms establishes different DNA-binding specificities across the Hox
locus. Mol Cell Biol. 16:1734–1745. 1996. View Article : Google Scholar : PubMed/NCBI
|
22
|
Li Z, Zhang Z, Li Y, Arnovitz S, Chen P,
Huang H, Jiang X, Hong GM, Kunjamma RB, Ren H, et al: PBX3 is an
important cofactor of HOXA9 in leukemogenesis. Blood.
121:1422–1431. 2013. View Article : Google Scholar : PubMed/NCBI
|
23
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
24
|
Muratovska A, Zhou C, He S, Goodyer P and
Eccles MR: Paired-Box genes are frequently expressed in cancer and
often required for cancer cell survival. Oncogene. 22:7989–7997.
2003. View Article : Google Scholar : PubMed/NCBI
|
25
|
Tan Y, Cheung M, Pei J, Menges CW, Godwin
AK and Testa JR: Upregulation of DLX5 promotes ovarian cancer cell
proliferation by enhancing IRS-2-AKT signaling. Cancer Res.
70:9197–9206. 2010. View Article : Google Scholar : PubMed/NCBI
|
26
|
Trinh BQ, Ko SY, Barengo N, Lin SY and
Naora H: Dual functions of the homeoprotein DLX4 in modulating
responsiveness of tumor cells to topoisomerase II-targeting drugs.
Cancer Res. 73:1000–1010. 2013. View Article : Google Scholar : PubMed/NCBI
|
27
|
Bruhl T, Urbich C, Aicher D, Acker-Palmer
A, Zeiher AM and Dimmeler S: Homeobox A9 transcriptionally
regulates the EphB4 receptor to modulate endothelial cell migration
and tube formation. Circ Res. 94:743–751. 2004. View Article : Google Scholar : PubMed/NCBI
|
28
|
Nakamura T, Largaespada DA, Lee MP,
Johnson LA, Ohyashiki K, Toyama K, Chen SJ, Willman CL, Chen IM,
Feinberg AP, et al: Fusion of the nucleoporin gene NUP98 to HOXA9
by the chromosome translocation t(7;11)(p15;p15) in human myeloid
leukaemia. Nat Genet. 12:154–158. 1996. View Article : Google Scholar : PubMed/NCBI
|
29
|
Bandyopadhyay S, Ashraf MZ, Daher P, Howe
PH and DiCorleto PE: HOXA9 participates in the transcriptional
activation of E-selectin in endothelial cells. Mol Cell Biol.
27:4207–4216. 2007. View Article : Google Scholar : PubMed/NCBI
|
30
|
Costa BM, Smith JS, Chen Y, Chen J,
Phillips HS, Aldape KD, Zardo G, Nigro J, James CD, Fridlyand J, et
al: Reversing HOXA9 oncogene activation by PI3K inhibition:
Epigenetic mechanism and prognostic significance in human
glioblastoma. Cancer Res. 70:453–462. 2010. View Article : Google Scholar : PubMed/NCBI
|
31
|
Chang CP, Shen WF, Rozenfeld S, Lawrence
HJ, Largman C and Cleary ML: Pbx proteins display
hexapeptide-dependent cooperative DNA binding with a subset of Hox
proteins. Genes Dev. 9:663–674. 1995. View Article : Google Scholar : PubMed/NCBI
|
32
|
Milech N, Kees UR and Watt PM: Novel
alternative PBX3 isoforms in leukemia cells with distinct
interaction specificities. Genes Chromosomes Cancer. 32:275–280.
2001. View
Article : Google Scholar : PubMed/NCBI
|
33
|
Li Z, Huang H, Li Y, Jiang X, Chen P,
Arnovitz S, Radmacher MD, Maharry K, Elkahloun A, Yang X, et al:
Up-regulation of a HOXA-PBX3 homeobox-gene signature following
down-regulation of miR-181 is associated with adverse prognosis in
patients with cytogenetically abnormal AML. Blood. 119:2314–2324.
2012. View Article : Google Scholar : PubMed/NCBI
|