|
1
|
Abbott A: Cell culture: Biology's new
dimension. Nature. 424:870–872. 2003. View
Article : Google Scholar : PubMed/NCBI
|
|
2
|
Weigelt B, Ghajar CM and Bissell MJ: The
need for complex 3D culture models to unravel novel pathways and
identify accurate biomarkers in breast cancer. Adv Drug Deliv Rev.
69–70:42–51. 2014. View Article : Google Scholar
|
|
3
|
Jacks T and Weinberg RA: Taking the study
of cancer cell survival to a new dimension. Cell. 111:923–925.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Breslin S and O'Driscoll L:
Three-dimensional cell culture: The missing link in drug discovery.
Drug Discov Today. 18:240–249. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Griffith LG and Swartz MA: Capturing
complex 3D tissue physiology in vitro. Nat Rev Mol Cell Biol.
7:211–224. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
6
|
Chen L, Xiao Z, Meng Y, Zhao Y, Han J, Su
G, Chen B and Dai J: The enhancement of cancer stem cell properties
of MCF-7 cells in 3D collagen scaffolds for modeling of cancer and
anti-cancer drugs. Biomaterials. 33:1437–1444. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Dhiman HK, Ray AR and Panda AK:
Three-dimensional chitosan scaffold-based MCF-7 cell culture for
the determination of the cytotoxicity of tamoxifen. Biomaterials.
26:979–986. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Fong EL, Lamhamedi-Cherradi SE, Burdett E,
Ramamoorthy V, Lazar AJ, Kasper FK, Farach-Carson MC, Vishwamitra
D, Demicco EG, Menegaz BA, et al: Modeling Ewing sarcoma tumors in
vitro with 3D scaffolds. Proc Natl Acad Sci USA. 110:pp. 6500–6505.
2013, View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Wästfelt M, Fadeel B and Henter JI: A
journey of hope: Lessons learned from studies on rare diseases and
orphan drugs. J Intern Med. 260:1–10. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Hutmacher DW: Biomaterials offer cancer
research the third dimension. Nat Mater. 9:90–93. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Shoemaker RH: The NCI60 human tumour cell
line anticancer drug screen. Nat Rev Cancer. 6:813–823. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Desrochers TM, Palma E and Kaplan DL:
Tissue-engineered kidney disease models. Adv Drug Deliv Rev.
69–70:67–80. 2014. View Article : Google Scholar
|
|
13
|
Cree IA, Glaysher S and Harvey AL:
Efficacy of anti-cancer agents in cell lines versus human primary
tumour tissue. Curr Opin Pharmacol. 10:375–379. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Uchida Y, Tanaka S, Aihara A, Adikrisna R,
Yoshitake K, Matsumura S, Mitsunori Y, Murakata A, Noguchi N, Irie
T, et al: Analogy between sphere forming ability and stemness of
human hepatoma cells. Oncol Rep. 24:1147–1151. 2010.PubMed/NCBI
|
|
15
|
Stevens JL and Baker TK: The future of
drug safety testing: Expanding the view and narrowing the focus.
Drug Discov Today. 14:162–167. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Huh D, Matthews BD, Mammoto A,
Montoya-Zavala M, Hsin HY and Ingber DE: Reconstituting organ-level
lung functions on a chip. Science. 328:1662–1668. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Russell WMS and Burch RL: The principles
of humane experimental technique. Methuen; London: 1959
|
|
18
|
Talukdar S and Kundu SC: A non-mulberry
silk fibroin protein based 3d in vitro tumor model for evaluation
of anticancer drug activity. Adv Funct Mat. 22:4778–4788. 2012.
View Article : Google Scholar
|
|
19
|
Dunne LW, Huang Z, Meng W, Fan X, Zhang N,
Zhang Q and An Z: Human decellularized adipose tissue scaffold as a
model for breast cancer cell growth and drug treatments.
Biomaterials. 35:4940–4949. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Maguire SL, Peck B, Wai PT, Campbell J,
Barker H, Gulati A, Daley F, Vyse S, Huang P, Lord CJ, et al:
Three-dimensional modelling identifies novel genetic dependencies
associated with breast cancer progression in the isogenic MCF10
model. J Pathol. 240:315–328. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Sha H, Zou Z, Xin K, Bian X, Cai X, Lu W,
Chen J, Chen G, Huang L, Blair AM, et al: Tumor-penetrating peptide
fused EGFR single-domain antibody enhances cancer drug penetration
into 3D multicellular spheroids and facilitates effective gastric
cancer therapy. J Control Release. 200:188–200. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Kundu B, Saha P, Datta K and Kundu SC: A
silk fibroin based hepatocarcinoma model and the assessment of the
drug response in hyaluronan-binding protein 1 overexpressed HepG2
cells. Biomaterials. 34:9462–9474. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Xu Z, Gao Y, Hao Y, Li E, Wang Y, Zhang J,
Wang W, Gao Z and Wang Q: Application of a microfluidic chip-based
3D co-culture to test drug sensitivity for individualized treatment
of lung cancer. Biomaterials. 34:4109–4117. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Simon KA, Mosadegh B, Minn KT, Lockett MR,
Mohammady MR, Boucher DM, Hall AB, Hillier SM, Udagawa T, Eustace
BK and Whitesides GM: Metabolic response of lung cancer cells to
radiation in a paper-based 3D cell culture system. Biomaterials.
95:47–59. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Stratmann AT, Fecher D, Wangorsch G,
Göttlich C, Walles T, Walles H, Dandekar T, Dandekar G and Nietzer
SL: Establishment of a human 3D lung cancer model based on a
biological tissue matrix combined with a Boolean in silico model.
Mol Oncol. 8:351–365. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Lee JM, Mhawech-Fauceglia P, Lee N,
Parsanian LC, Lin YG, Gayther SA and Lawrenson K: A
three-dimensional microenvironment alters protein expression and
chemosensitivity of epithelial ovarian cancer cells in vitro. Lab
Invest. 93:528–542. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Shin CS, Kwak B, Han B and Park K:
Development of an in vitro 3D tumor model to study therapeutic
efficiency of an anticancer drug. Mol Pharm. 10:2167–2175. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Loessner D, Rizzi SC, Stok KS, Fuehrmann
T, Hollier B, Magdolen V, Hutmacher DW and Clements JA: A
bioengineered 3D ovarian cancer model for the assessment of
peptidase-mediated enhancement of spheroid growth and
intraperitoneal spread. Biomaterials. 34:7389–7400. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Yang Z and Zhao X: A 3D model of ovarian
cancer cell lines on peptide nanofiber scaffold to explore the
cell-scaffold interaction and chemotherapeutic resistance of
anticancer drugs. Int J Nanomedicine. 6:303–310. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Fitzgerald KA, Guo J, Tierney EG, Curtin
CM, Malhotra M, Darcy R, O'Brien FJ and O'Driscoll CM: The use of
collagen-based scaffolds to simulate prostate cancer bone
metastases with potential for evaluating delivery of
nanoparticulate gene therapeutics. Biomaterials. 66:53–66. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Xu X, Sabanayagam CR, Harrington DA,
Farach-Carson MC and Jia X: A hydrogel-based tumor model for the
evaluation of nanoparticle-based cancer therapeutics. Biomaterials.
35:3319–3330. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Lv D, Yu SC, Ping YF, Wu H, Zhao X, Zhang
H, Cui Y, Chen B, Zhang X, Dai J, et al: A three-dimensional
collagen scaffold cell culture system for screening anti-glioma
therapeutics. Oncotarget. 7:56904–56914. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Ma NK, Lim JK, Leong MF, Sandanaraj E, Ang
BT, Tang C and Wan AC: Collaboration of 3D context and
extracellular matrix in the development of glioma stemness in a 3D
model. Biomaterials. 78:62–73. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Pedron S, Becka E and Harley BA:
Regulation of glioma cell phenotype in 3D matrices by hyaluronic
acid. Biomaterials. 34:7408–7417. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Munson JM, Bellamkonda RV and Swartz MA:
Interstitial flow in a 3D microenvironment increases glioma
invasion by a CXCR4-dependent mechanism. Cancer Res. 73:1536–1546.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Fennema E, Rivron N, Rouwkema J, van
Blitterswijk C and de Boer J: Spheroid culture as a tool for
creating 3D complex tissues. Trends Biotechnol. 31:108–115. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Friedrich J, Seidel C, Ebner R and
Kunz-Schughart LA: Spheroid-based drug screen: Considerations and
practical approach. Nat Protoc. 4:309–324. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Reynolds BA and Weiss S: Generation of
neurons and astrocytes from isolated cells of the adult mammalian
central nervous system. Science. 255:1707–1710. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Yu SC, Ping YF, Yi L, Zhou ZH, Chen JH,
Yao XH, Gao L, Wang JM and Bian XW: Isolation and characterization
of cancer stem cells from a human glioblastoma cell line U87.
Cancer Lett. 265:124–134. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Yuhas JM, Li AP, Martinez AO and Ladman
AJ: A simplified method for production and growth of multicellular
tumor spheroids. Cancer Res. 37:3639–3643. 1977.PubMed/NCBI
|
|
41
|
Lawlor ER, Scheel C, Irving J and Sorensen
PH: Anchorage-independent multi-cellular spheroids as an in vitro
model of growth signaling in Ewing tumors. Oncogene. 21:307–318.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Lin RZ and Chang HY: Recent advances in
three-dimensional multicellular spheroid culture for biomedical
research. Biotechnol J. 3:1172–1184. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Pang R, Law WL, Chu AC, Poon JT, Lam CS,
Chow AK, Ng L, Cheung LW, Lan XR, Lan HY, et al: A subpopulation of
CD26+ cancer stem cells with metastatic capacity in human
colorectal cancer. Cell Stem Cell. 6:603–615. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Ivascu A and Kubbies M: Rapid generation
of single-tumor spheroids for high-throughput cell function and
toxicity analysis. J Biomol Screen. 11:922–932. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Louis SA, Rietze RL, Deleyrolle L, Wagey
RE, Thomas TE, Eaves AC and Reynolds BA: Enumeration of neural stem
and progenitor cells in the neural colony-forming cell assay. Stem
Cells. 26:988–996. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Ng KW, Leong DT and Hutmacher DW: The
challenge to measure cell proliferation in two and three
dimensions. Tissue Eng. 11:182–191. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Kelm JM, Timmins NE, Brown CJ, Fussenegger
M and Nielsen LK: Method for generation of homogeneous
multicellular tumor spheroids applicable to a wide variety of cell
types. Biotechnol Bioeng. 83:173–180. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Tung YC, Hsiao AY, Allen SG, Torisawa YS,
Ho M and Takayama S: High-throughput 3D spheroid culture and drug
testing using a 384 hanging drop array. Analyst. 136:473–478. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Zanetta M, Quirici N, Demarosi F, Tanzi
MC, Rimondini L and Farè S: Ability of polyurethane foams to
support cell proliferation and the differentiation of MSCs into
osteoblasts. Acta Biomater. 5:1126–1136. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Souza GR, Molina JR, Raphael RM, Ozawa MG,
Stark DJ, Levin CS, Bronk LF, Ananta JS, Mandelin J, Georgescu MM,
et al: Three-dimensional tissue culture based on magnetic cell
levitation. Nat Nanotechnol. 5:291–296. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Su J, Zhang L, Zhang W, Choi DS, Wen J,
Jiang B, Chang CC and Zhou X: Targeting the biophysical properties
of the myeloma initiating cell niches: A pharmaceutical synergism
analysis using multi-scale agent-based modeling. PLoS One.
9:e850592014. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Durand RE and Sutherland RM: Effects of
intercellular contact on repair of radiation damage. Exp Cell Res.
71:75–80. 1972. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Goodwin TJ, Prewett TL, Wolf DA and
Spaulding GF: Reduced shear stress: A major component in the
ability of mammalian tissues to form three-dimensional assemblies
in simulated microgravity. J Cell Biochem. 51:301–311. 1993.
View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Chen X, Xu H, Wan C, McCaigue M and Li G:
Bioreactor expansion of human adult bone marrow-derived mesenchymal
stem cells. Stem Cells. 24:2052–2059. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Luni C, Feldman HC, Pozzobon M, De Coppi
P, Meinhart CD and Elvassore N: Microliter-bioreactor array with
buoyancy-driven stirring for human hematopoietic stem cell culture.
Biomicrofluidics. 4:pii: 034105. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Chang TT and Hughes-Fulford M: Monolayer
and spheroid culture of human liver hepatocellular carcinoma cell
line cells demonstrate distinct global gene expression patterns and
functional phenotypes. Tissue Eng Part A. 15:559–567. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Redden RA and Doolin EJ: Microgravity
assay of neuroblastoma: In vitro aggregation kinetics and organoid
morphology correlate with MYCN expression. In Vitro Cell Dev Biol
Anim. 47:312–317. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Kaur P, Ward B, Saha B, Young L, Groshen
S, Techy G, Lu Y, Atkinson R, Taylor CR, Ingram M and Imam SA:
Human breast cancer histoid: An in vitro 3-dimensional co-culture
model that mimics breast cancer tissue. J Histochem Cytochem.
59:1087–1100. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Marrero B, Messina JL and Heller R:
Generation of a tumor spheroid in a microgravity environment as a
3D model of melanoma. In Vitro Cell Dev Biol Anim. 45:523–534.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Zhang Z and Nagrath S: Microfluidics and
cancer: Are we there yet? Biomed Microdevices. 15:595–609. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Mehta G, Hsiao AY, Ingram M, Luker GD and
Takayama S: Opportunities and challenges for use of tumor spheroids
as models to test drug delivery and efficacy. J Control Release.
164:192–204. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Gill BJ and West JL: Modeling the tumor
extracellular matrix: Tissue engineering tools repurposed towards
new frontiers in cancer biology. J Biomech. 47:1969–1978. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Loessner D, Stok KS, Lutolf MP, Hutmacher
DW, Clements JA and Rizzi SC: Bioengineered 3D platform to explore
cell-ECM interactions and drug resistance of epithelial ovarian
cancer cells. Biomaterials. 31:8494–8506. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Nirmalanandhan VS, Duren A, Hendricks P,
Vielhauer G and Sittampalam GS: Activity of anticancer agents in a
three-dimensional cell culture model. Assay Drug Dev Technol.
8:581–590. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Freeman AE and Hoffman RM: In vivo-like
growth of human tumors in vitro. Proc Natl Acad Sci USA. 83:pp.
2694–2698. 1986, View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Takamura Y, Kobayashi H, Taguchi T,
Motomura K, Inaji H and Noguchi S: Prediction of chemotherapeutic
response by collagen gel droplet embedded culture-drug sensitivity
test in human breast cancers. Int J Cancer. 98:450–455. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Yang J, Richards J, Bowman P, Guzman R,
Enami J, McCormick K, Hamamoto S, Pitelka D and Nandi S: Sustained
growth and three-dimensional organization of primary mammary tumor
epithelial cells embedded in collagen gels. Proc Natl Acad Sci USA.
76:pp. 3401–3405. 1979, View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Rowehl RA, Burke S, Bialkowska AB, Pettet
DW III, Rowehl L, Li E, Antoniou E, Zhang Y, Bergamaschi R, Shroyer
KR, et al: Establishment of highly tumorigenic human colorectal
cancer cell line (CR4) with properties of putative cancer stem
cells. PLoS One. 9:e990912014. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Yip D and Cho CH: A multicellular 3D
heterospheroid model of liver tumor and stromal cells in collagen
gel for anti-cancer drug testing. Biochem Biophys Res Commun.
433:327–332. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Rao SS, Dejesus J, Short AR, Otero JJ,
Sarkar A and Winter JO: Glioblastoma behaviors in three-dimensional
collagen-hyaluronan composite hydrogels. ACS Appl Mater Interfaces.
5:9276–9284. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Dvir-Ginzberg M, Gamlieli-Bonshtein I,
Agbaria R and Cohen S: Liver tissue engineering within alginate
scaffolds: Effects of cell-seeding density on hepatocyte viability,
morphology, and function. Tissue Eng. 9:757–766. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Zhang X, Wang W, Yu W, Xie Y, Zhang Y and
Ma X: Development of an in vitro multicellular tumor spheroid model
using microencapsulation and its application in anticancer drug
screening and testing. Biotechnol Prog. 21:1289–1296. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Xu XX, Liu C, Liu Y, Yang L, Li N, Guo X,
Sun GW and Ma XJ: Enrichment of cancer stem cell-like cells by
culture in alginate gel beads. J Biotechnol. 177:1–12. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Kleinman HK and Martin GR: Matrigel:
Basement membrane matrix with biological activity. Semin Cancer
Biol. 15:378–386. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Wang F, Weaver VM, Petersen OW, Larabell
CA, Dedhar S, Briand P, Lupu R and Bissell MJ: Reciprocal
interactions between beta1-integrin and epidermal growth factor
receptor in three-dimensional basement membrane breast cultures: A
different perspective in epithelial biology. Proc Natl Acad Sci
USA. 95:pp. 14821–14826. 1998, View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Ampuja M, Jokimäki R, Juuti-Uusitalo K,
Rodriguez-Martinez A, Alarmo EL and Kallioniemi A: BMP4 inhibits
the proliferation of breast cancer cells and induces an
MMP-dependent migratory phenotype in MDA-MB-231 cells in 3D
environment. BMC Cancer. 13:4292013. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Christensen M, Najy AJ, Snyder M, Movilla
LS and Kim HR: A critical role of the PTEN/PDGF signaling network
for the regulation of radiosensitivity in adenocarcinoma of the
prostate. Int J Radiat Oncol Biol Phys. 88:151–158. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Valyi-Nagy K, Kormos B, Ali M, Shukla D
and Valyi-Nagy T: Stem cell marker CD271 is expressed by
vasculogenic mimicry-forming uveal melanoma cells in
three-dimensional cultures. Mol Vis. 18:588–592. 2012.PubMed/NCBI
|
|
79
|
Lombardo Y, Filipović A, Molyneux G,
Periyasamy M, Giamas G, Hu Y, Trivedi PS, Wang J, Yagüe E, Michel L
and Coombes RC: Nicastrin regulates breast cancer stem cell
properties and tumor growth in vitro and in vivo. Proc Natl Acad
Sci USA. 109:pp. 16558–16563. 2012, View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Sodunke TR, Turner KK, Caldwell SA,
McBride KW, Reginato MJ and Noh HM: Micropatterns of Matrigel for
three-dimensional epithelial cultures. Biomaterials. 28:4006–4016.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Carletti E, Motta A and Migliaresi C:
Scaffolds for tissue engineering and 3D cell culture. Methods Mol
Biol. 695:17–39. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Liu X, Holzwarth JM and Ma PX:
Functionalized synthetic biodegradable polymer scaffolds for tissue
engineering. Macromol Biosci. 12:911–919. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Feng S, Duan X, Lo PK, Liu S, Liu X, Chen
H and Wang Q: Expansion of breast cancer stem cells with fibrous
scaffolds. Integr Biol (Camb). 5:768–777. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Chen J, Wang J, Zhang Y, Chen D, Yang C,
Kai C, Wang X, Shi F and Dou J: Observation of ovarian cancer stem
cell behavior and investigation of potential mechanisms of drug
resistance in three-dimensional cell culture. J Biosci Bioeng.
118:214–222. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Kievit FM, Florczyk SJ, Leung MC, Wang K,
Wu JD, Silber JR, Ellenbogen RG, Lee JS and Zhang M: Proliferation
and enrichment of CD133(+) glioblastoma cancer stem cells on 3D
chitosan-alginate scaffolds. Biomaterials. 35:9137–9143. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
86
|
Amann A, Zwierzina M, Gamerith G, Bitsche
M, Huber JM, Vogel GF, Blumer M, Koeck S, Pechriggl EJ, Kelm JM, et
al: Development of an innovative 3D cell culture system to study
tumour-stroma interactions in non-small cell lung cancer cells.
PLoS One. 9:e925112014. View Article : Google Scholar : PubMed/NCBI
|
|
87
|
Hoque MT, Windus LC, Lovitt CJ and Avery
VM: PCaAnalyser: A 2D-image analysis based module for effective
determination of prostate cancer progression in 3D culture. PLoS
One. 8:e798652013. View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Ciurea ME, Georgescu AM, Purcaru SO,
Artene SA, Emami GH, Boldeanu MV, Tache DE and Dricu A: Cancer stem
cells: Biological functions and therapeutically targeting. Int J
Mol Sci. 15:8169–8185. 2014. View Article : Google Scholar : PubMed/NCBI
|