|
1
|
Graeber MB and Streit WJ: Microglia:
Biology and pathology. Acta Neuropathol. 119:89–105. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lawson LJ, Perry VH, Dri P and Gordon S:
Heterogeneity in the distribution and morphology of microglia in
the normal adult mouse brain. Neuroscience. 39:151–170. 1990.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Kettenmann H, Hanisch UK, Noda M and
Verkhratsky A: Physiology of microglia. Physiol Rev. 91:461–553.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Simmons GW, Pong WW, Emnett RJ, White CR,
Gianino SM, Rodriguez FJ and Gutmann DH: Neurofibromatosis-1
heterozygosity increases microglia in a spatially-and
temporally-restricted pattern relevant to mouse optic glioma
formation and growth. J Neuropathol Exp Neurol. 70:51–62. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Klein R and Roggendorf W: Increased
microglia proliferation separates pilocytic astrocytomas from
diffuse astrocytomas: A double labeling study. Acta Neuropathol.
101:245–248. 2001.PubMed/NCBI
|
|
6
|
Komohara Y, Ohnishi K, Kuratsu J and
Takeya M: Possible involvement of the M2 anti-inflammatory
macrophage phenotype in growth of human gliomas. J Pathol.
216:15–24. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Shinonaga M, Chang CC, Suzuki N, Sato M
and Kuwabara T: Immunohistological evaluation of macrophage
infiltrates in brain tumors. Correlation with peritumoral edema. J
Neurosurg. 68:259–265. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Roggendorf W, Strupp S and Paulus W:
Distribution and characterization of microglia/macrophages in human
brain tumors. Acta Neuropathol. 92:288–293. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Nishie A, Ono M, Shono T, Fukushi J,
Otsubo M, Onoue H, Ito Y, Inamura T, Ikezaki K, Fukui M, et al:
Macrophage infiltration and heme oxygenase-1 expression correlate
with angiogenesis in human gliomas. Clin Cancer Res. 5:1107–1113.
1999.PubMed/NCBI
|
|
10
|
Badie B and Schartner JM: Flow cytometric
characterization of tumor-associated macrophages in experimental
gliomas. Neurosurgery. 46:957–962. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Watters JJ, Schartner JM and Badie B:
Microglia function in brain tumors. J Neurosci Res. 81:447–455.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Markovic DS, Vinnakota K, Chirasani S,
Synowitz M, Raguet H, Stock K, Sliwa M, Lehmann S, Kälin R, van
Rooijen N, et al: Gliomas induce and exploit microglial MT1-MMP
expression for tumor expansion. Proc Natl Acad Sci USA. 106:pp.
12530–12535. 2009; View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Zhai H, Heppner FL and Tsirka SE:
Microglia/macrophages promote glioma progression. Glia. 59:472–485.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kaminska B: Microglia in Gliomas: Friend
or Foe?Glioma Cell Biology. Sedo A and Mentlein R: Springer-Verlag;
Berlin: pp. 241–270. 2014
|
|
15
|
Schiffer D, Mellai M, Bovio E and
Annovazzi L: The neuropathological basis to the functional role of
microglia/macrophages in gliomas. Neurol Sci. 2017. View Article : Google Scholar
|
|
16
|
Gabrusiewicz K, Ellert-Miklaszewska A,
Lipko M, Sielska M, Frankowska M and Kaminska B: Characteristics of
the alternative phenotype of microglia/macrophages and its
modulation in experimental gliomas. PLoS One. 6:e239022011.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Durafourt BA, Moore CS, Zammit DA, Johnson
TA, Zaguia F, Guiot MC, Bar-Or A and Antel JP: Comparison of
polarization properties of human adult microglia and blood-derived
macrophages. Glia. 60:717–727. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Perry VH and Teeling J: Microglia and
macrophages of the central nervous system: The contribution of
microglia priming and systemic inflammation to chronic
neurodegeneration. Semin Immunopathol. 35:601–612. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Glass R and Synowitz M: CNS macrophages
and peripheral myeloid cells in brain tumours. Acta Neuropathol.
128:347–362. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Szulzewsky F, Pelz A, Feng X, Synowitz M,
Markovic D, Langmann T, Holtman IR, Wang X, Eggen BJ, Boddeke HW,
et al: Glioma-associated microglia/macrophages display an
expression profile different from M1 and M2 polarization and highly
express Gpnmb and Spp1. PLoS One. 10:e01166442015. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Hussain SF, Yang D, Suki D, Aldape K,
Grimm E and Heimberger AB: The role of human glioma-infiltrating
microglia/macrophages in mediating antitumor immune responses.
Neuro Oncol. 8:261–279. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Parney IF, Waldron JS and Parsa AT: Flow
cytometry and in vitro analysis of human glioma-associated
macrophages. Laboratory investigation. J Neurosurg. 110:572–582.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Li W and Graeber MB: The molecular profile
of microglia under the influence of glioma. Neuro Oncol.
14:958–978. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Wei J, Gabrusiewicz K and Heimberger A:
The controversial role of microglia in malignant gliomas. Clin Dev
Immunol. 2013:2852462013. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Prinz M, Tay TL, Wolf Y and Jung S:
Microglia: Unique and common features with other tissue
macrophages. Acta Neuropathol. 128:319–331. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hambardzumyan D, Gutmann DH and Kettenmann
H: The role of microglia and macrophages in glioma maintenance and
progression. Nat Neurosci. 19:20–27. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Müller A, Brandenburg S, Turkowski K,
Müller S and Vajkoczy P: Resident microglia, and not peripheral
macrophages, are the main source of brain tumor mononuclear cells.
Int J Cancer. 137:278–288. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Zhou W, Ke SQ, Huang Z, Flavahan W, Fang
X, Paul J, Wu L, Sloan AE, McLendon RE, Li X, et al: Periostin
secreted by glioblastoma stem cells recruits M2 tumour-associated
macrophages and promotes malignant growth. Nat Cell Biol.
17:170–182. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Szulzewsky F, Arora S, de Witte L, Ulas T,
Markovic D, Schultze JL, Holland EC, Synowitz M, Wolf SA and
Kettenmann H: Human glioblastoma-associated microglia/monocytes
express a distinct RNA profile compared to human control and murine
samples. Glia. 64:1416–1436. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kennedy BC, Showers CR, Anderson DE,
Anderson L, Canoll P, Bruce JN and Anderson RC: Tumor-associated
macrophages in glioma: Friend or foe? J Oncol 2013. 4869122013.
|
|
31
|
Wu A, Wei J, Kong LY, Wang Y, Priebe W,
Qiao W, Sawaya R and Heimberger AB: Glioma cancer stem cells induce
immunosuppressive macrophages/microglia. Neuro Oncol. 12:1113–1125.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Ye XZ, Xu SL, Xin YH, Yu SC, Ping YF, Chen
L, Xiao HL, Wang B, Yi L, Wang QL, et al: Tumor-associated
microglia/macrophages enhance the invasion of glioma stem-like
cells via TGF-β1 signaling pathway. J Immunol. 189:444–453. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Brandenburg S, Müller A, Turkowski K,
Radev YT, Rot S, Schmidt C, Bungert AD, Acker G, Schorr A, Hippe A,
et al: Resident microglia rather than peripheral macrophages
promote vascularization in brain tumors and are source of
alternative pro-angiogenic factors. Acta Neuropathol. 131:365–378.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Coniglio S, Miller I, Symons M and Segall
JE: Coculture assays to study macrophage and microglia stimulation
of glioblastoma invasion. J Vis Exp. 20:1162016.
|
|
35
|
Louis DN, Ohgaki H, Wiestler OD and
Cavenee WK: WHO classification of tumours of the Central Nervous
System. 4th. IARC Press; Lyon: pp. 1–408. 2016
|
|
36
|
Mellai M, Piazzi A, Caldera V, Monzeglio
O, Cassoni P, Valente G and Schiffer D: IDH1 and IDH2 mutations,
immunohistochemistry and associations in a series of brain tumors.
J Neurooncol. 105:345–357. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Kondo S and Okabe S: In vivo two-photon
microscopy of microglia. Methods Mol Biol. 1041:319–335. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Bayerl SH, Niesner R, Cseresnyes Z,
Radbruch H, Pohlan J, Brandenburg S, Czabanka MA and Vajkoczy P:
Time lapse in vivo microscopy reveals distinct dynamics of
microglia-tumor environment interactions-a new role for the tumor
perivascular space as highway for trafficking microglia. Glia.
64:1210–1226. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Nimmerjahn A: Two-photon imaging of
microglia in the mouse cortex in vivo. Cold Spring Harb Protoc.
5:pii: pdb.prot069294. 2012.
|
|
40
|
Greter M, Lelios I and Croxford AL:
Microglia versus myeloid cell nomenclature during brain
inflammation. Front Immunol. 6:2492015. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Barros MH, Hauck F, Dreyer JH, Kempkes B
and Niedobitek G: Macrophage polarisation: An immunohistochemical
approach for identifying M1 and M2 macrophages. PLoS One.
8:e809082013. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
da Fonseca AC and Badie B: Microglia and
macrophages in malignant gliomas: Recent discoveries and
implications for promising therapies. Clin Dev Immunol.
2013:2641242013.PubMed/NCBI
|
|
43
|
Morioka T, Baba T, Black KL and Streit WJ:
Immunophenotypic analysis of infiltrating leukocytes and microglia
in an experimental rat glioma. Acta Neuropathol. 83:590–597. 1992.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Morimura T, Neuchrist C, Kitz K, Budka H,
Scheiner O, Kraft D and Lassmann H: Monocyte subpopulations in
human gliomas: Expression of Fc and complement receptors and
correlation with tumor proliferation. Acta Neuropathol. 80:287–294.
1990. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Vinnakota K, Hu F, Ku MC, Georgieva PB,
Szulzewsky F, Pohlmann A, Waiczies S, Waiczies H, Niendorf T,
Lehnardt S, et al: Toll-like receptor 2 mediates microglia/brain
macrophage MT1-MMP expression and glioma expansion. Neuro Oncol.
15:1457–1468. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Schiffer D: Pathology and
neuroepidemiology of the brain and nervous system. Curr Opin Oncol.
3:449–458. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Hochreiter-Hufford A and Ravichandran KS:
Clearing the dead: Apoptotic cell sensing, recognition, engulfment,
and digestion. Cold Spring Harb Perspect Biol. 5:a0087482013.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Kamper P, Bendix K, Hamilton-Dutoit S,
Honoré B, Nyengaard JR and d'Amore F: Tumor-infiltrating
macrophages correlate with adverse prognosis and Epstein-Barr virus
status in classical Hodgkin's lymphoma. Haematologica. 96:269–276.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Zaki MA, Wada N, Ikeda J, Shibayama H,
Hashimoto K, Yamagami T, Tatsumi Y, Tsukaguchi M, Take H, Tsudo M,
et al: Prognostic implication of types of tumor-associated
macrophages in Hodgkin lymphoma. Virchows Arch. 459:361–366. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Ino Y, Yamazaki-Itoh R, Shimada K, Iwasaki
M, Kosuge T, Kanai Y and Hiraoka N: Immune cell infiltration as an
indicator of the immune microenvironment of pancreatic cancer. Br J
Cancer. 108:914–923. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Herrera M, Herrera A, Domínguez G, Silva
J, García V, García JM, Gómez I, Soldevilla B, Muñoz C, Provencio
M, et al: Cancer-associated fibroblast and M2 macrophage markers
together predict outcome in colorectal cancer patients. Cancer Sci.
104:437–444. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Forstreuter F, Lucius R and Mentlein R:
Vascular endothelial growth factor induces chemotaxis and
proliferation of microglial cells. J Neuroimmunol. 132:93–98. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Kerber M, Reiss Y, Wickersheim A, Jugold
M, Kiessling F, Heil M, Tchaikovski V, Waltenberger J, Shibuya M,
Plate KH and Machein MR: Flt-1 signaling in macrophages promotes
glioma growth in vivo. Cancer Res. 68:7342–7351. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Li Y, Liu DX, Li MY, Qin XX, Fang WG, Zhao
WD and Chen YH: Ephrin-A3 and ephrin-A4 contribute to
microglia-induced angiogenesis in brain endothelial cells. Anat Rec
(Hoboken). 297:1908–1918. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Rymo SF, Gerhardt H, Wolfhagen Sand F,
Lang R, Uv A and Betsholtz C: A two-way communication between
microglial cells and angiogenic sprouts regulates angiogenesis in
aortic ring cultures. PLoS One. 6:e158462011. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Ding P, Wang W, Wang J, Yang Z and Xue L:
Expression of tumor-associated macrophage in progression of human
glioma. Cell Biochem Biophys. 70:1625–1631. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Mantovani A, Allavena P and Sica A:
Tumour-associated macrophages as a prototypic type II polarised
phagocyte population: Role in tumour progression. Eur J Cancer.
40:1660–1667. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Lan C, Huang X, Lin S, Huang H, Cai Q, Wan
T, Lu J and Liu J: Expression of M2-polarized macrophages is
associated with poor prognosis for advanced epithelial ovarian
cancer. Technol Cancer Res Treat. 12:259–267. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Edin S, Wikberg ML, Dahlin AM, Rutegård J,
Öberg Å, Oldenborg PA and Palmqvist R: The distribution of
macrophages with a M1 or M2 phenotype in relation to prognosis and
the molecular characteristics of colorectal cancer. PLoS One.
7:e470452012. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Lisi L, Stigliano E, Lauriola L, Navarra P
and Dello Russo C: Proinflammatory-activated glioma cells induce a
switch in microglial polarization and activation status, from a
predominant M2b phenotype to a mixture of M1 and M2a/B polarized
cells. ASN Neuro. 6:171–183. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Noorani I, Petty G, Grundy PL, Sharpe G,
Willaime-Morawek S, Harris S, Thomas GJ, Nicoll JA and Boche D:
Novel association between microglia and stem cells in human
gliomas: A contributor to tumour proliferation? J Pathol Clin Res.
1:67–75. 2015. View
Article : Google Scholar : PubMed/NCBI
|
|
62
|
Takeuchi H, Kubota T, Kitai R, Nakagawa T
and Hashimoto N: CD98 immunoreactivity in multinucleated giant
cells of glioblastomas: An immunohistochemical double labeling
study. Neuropathology. 28:127–131. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Huysentruyt LC, Akgoc Z and Seyfried TN:
Hypothesis: Are neoplastic macrophages/microglia present in
glioblastoma multiforme? ASN Neuro. 3(pii): e000642011.PubMed/NCBI
|
|
64
|
Bjerknes R, Bjerkvig R and Laerum OD:
Phagocytic capacity of normal and malignant rat glial cells in
culture. J Natl Cancer Inst. 78:279–288. 1987.PubMed/NCBI
|
