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Pediatric sarcomas (Review)

Retraction in: /10.3892/ol.2018.7943
  • Authors:
    • Junhua Cao
    • Qi An
    • Lei Wang
  • View Affiliations / Copyright

    Affiliations: Department of Pediatric Internal Medicine, Xuzhou Children's Hospital, Xuzhou, Jiangsu 221002, P.R. China
    Copyright: © Cao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1397-1402
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    Published online on: November 21, 2017
       https://doi.org/10.3892/ol.2017.7467
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Abstract

Sarcomas arise from primitive mesenchymal cells, which are classified, into two main groups: Bone and soft tissue sarcomas. We have searched all-important electronic databases including Google scholar and PubMed for the collection of latest literature pertaining to pediatric sarcomas. Latest literature confirmed that these tumors are relatively rare and represent only 1% of all malignancies but they have higher incidence in children. Pediatric sarcomas comprise about 13% of all pediatric malignancies and are ranked third in childhood cancers. The highest incidence rates are reported among rhabdomyosarcoma, osteosarcoma and Ewing's sarcomas in children. All of these neoplasms often display highly aggressive behavior with tendency to form metastases. Important globally used management avenues include surgery with systemic chemotherapy and have success rate of 70% at 5-years. Furthermore, in the cases of advanced stages, the prognosis is poor, chances of treatment failure and recurrence are quite high. Utilization of cancer stem cells is the latest approach with great potential in management of above pathological state. The present review article discuss all-important aspects of commonly found pediatric sarcomas throughout the world.
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1 

van der Graaf WT, Orbach D, Judson IR and Ferrari A: Soft tissue sarcomas in adolescents and young adults: A comparison with their paediatric and adult counterparts. Lancet Oncol. 18:e166–e175. 2017. View Article : Google Scholar : PubMed/NCBI

2 

Kager L, Tamamyan G and Bielack S: Novel insights and therapeutic interventions for pediatric osteosarcoma. Future Oncol. 13:357–368. 2017. View Article : Google Scholar : PubMed/NCBI

3 

Weiss A, Gill J, Goldberg J, Lagmay J, Spraker-Perlman H, Venkatramani R and Reed D: Advances in therapy for pediatric sarcomas. Curr Oncol Rep. 16:3952014. View Article : Google Scholar : PubMed/NCBI

4 

Luetke A, Meyers PA, Lewis I and Juergens H: Osteosarcoma treatment - where do we stand? A state of the art review. Cancer Treat Rev. 40:523–532. 2014. View Article : Google Scholar : PubMed/NCBI

5 

Dela Cruz FS: Cancer stem cells in pediatric sarcomas. Front Oncol. 3:1682013.PubMed/NCBI

6 

Gibbs CP, Kukekov VG, Reith JD, Tchigrinova O, Suslov ON, Scott EW, Ghivizzani SC, Ignatova TN and Steindler DA: Stem-like cells in bone sarcomas: Implications for tumorigenesis. Neoplasia. 7:967–976. 2005. View Article : Google Scholar : PubMed/NCBI

7 

Tsuchida R, Das B, Yeger H, Koren G, Shibuya M, Thorner PS, Baruchel S and Malkin D: Cisplatin treatment increases survival and expansion of a highly tumorigenic side-population fraction by upregulating VEGF/Flt1 autocrine signaling. Oncogene. 27:3923–3934. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Di Fiore R, Santulli A, Ferrante RD, Giuliano M, De Blasio A, Messina C, Pirozzi G, Tirino V, Tesoriere G and Vento R: Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment. J Cell Physiol. 219:301–313. 2009. View Article : Google Scholar : PubMed/NCBI

9 

Tirino V, Desiderio V, D'Aquino R, de Francesco F, Pirozzi G, Graziano A, Galderisi U, Cavaliere C, de Rosa A, Papaccio G, et al: Detection and characterization of CD133+ cancer stem cells in human solid tumours. PLoS One. 3:e34692008. View Article : Google Scholar : PubMed/NCBI

10 

Veselska R, Kuglik P, Cejpek P, Svachova H, Neradil J, Loja T and Relichova J: Nestin expression in the cell lines derived from glioblastoma multiforme. BMC Cancer. 6:322006. View Article : Google Scholar : PubMed/NCBI

11 

Tirino V, Desiderio V, Paino F, De Rosa A, Papaccio F, Fazioli F, Pirozzi G and Papaccio G: Human primary bone sarcomas contain CD133+ cancer stem cells displaying high tumorigenicity in vivo. FASEB J. 25:2022–2030. 2011. View Article : Google Scholar : PubMed/NCBI

12 

Yang M, Yan M, Zhang R, Li J and Luo Z: Side population cells isolated from human osteosarcoma are enriched with tumor-initiating cells. Cancer Sci. 102:1774–1781. 2011. View Article : Google Scholar : PubMed/NCBI

13 

Adhikari AS, Agarwal N, Wood BM, Porretta C, Ruiz B, Pochampally RR and Iwakuma T: CD117 and Stro-1 identify osteosarcoma tumor-initiating cells associated with metastasis and drug resistance. Cancer Res. 70:4602–4612. 2010. View Article : Google Scholar : PubMed/NCBI

14 

Penfornis P, Cai DZ, Harris MR, Walker R, Licini D, Fernandes JD, Orr G, Koganti T, Hicks C, Induru S, et al: High CD49f expression is associated with osteosarcoma tumor progression: A study using patient-derived primary cell cultures. Cancer Med. 3:796–811. 2014. View Article : Google Scholar : PubMed/NCBI

15 

Ying M, Liu G, Shimada H, Ding W, May WA, He Q, Adams GB and Wu L: Human osteosarcoma CD49f(−)CD133(+) cells: Impaired in osteogenic fate while gain of tumorigenicity. Oncogene. 32:4252–4263. 2013. View Article : Google Scholar : PubMed/NCBI

16 

Wilkens S: Structure and mechanism of ABC transporters. F1000 Prime Rep. 7:142015. View Article : Google Scholar

17 

Martins-Neves SR, Paiva-Oliveira DI, Wijers-Koster PM, Abrunhosa AJ, Fontes-Ribeiro C, Bovée JV, Cleton-Jansen AM and Gomes CM: Chemotherapy induces stemness in osteosarcoma cells through activation of Wnt/β-catenin signaling. Cancer Lett. 370:286–295. 2016. View Article : Google Scholar : PubMed/NCBI

18 

Martins-Neves SR, Corver WE, Paiva-Oliveira DI, Van Den Akker BE, Briaire-de-Bruijn IH, Bovee JV, Gomes CM and Cleton-Jansen AM: Osteosarcoma stem cells have active Wnt/beta-catenin and Overexpress SOX2 and KLF4. J Cell Physiol. 231:876–886. 2016. View Article : Google Scholar : PubMed/NCBI

19 

Wang L, Park P, Zhang H, La Marca F and Lin CY: Prospective identification of tumorigenic osteosarcoma cancer stem cells in OS99-1 cells based on high aldehyde dehydrogenase activity. Int J Cancer. 128:294–303. 2011. View Article : Google Scholar : PubMed/NCBI

20 

Greco N, Schott T, Mu X, Rothenberg A, Voigt C, McGough RL III, Goodman M, Huard J and Weiss KR: ALDH Activity correlates with metastatic potential in primary sarcomas of bone. J Cancer Ther. 5:331–338. 2014. View Article : Google Scholar : PubMed/NCBI

21 

Weina K and Utikal J: SOX2 and cancer: Current research and its implications in the clinic. Clin Transl Med. 3:192014. View Article : Google Scholar : PubMed/NCBI

22 

Yang C, Hou C, Zhang H, Wang D, Ma Y, Zhang Y, Xu X, Bi Z and Geng S: miR-126 functions as a tumor suppressor in osteosarcoma by targeting Sox2. Int J Mol Sci. 15:423–437. 2013. View Article : Google Scholar : PubMed/NCBI

23 

Basu-Roy U, Bayin NS, Rattanakorn K, Han E, Placantonakis DG, Mansukhani A and Basilico C: Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells. Nat Commun. 6:64112015. View Article : Google Scholar : PubMed/NCBI

24 

Balamuth NJ and Womer RB: Ewing's sarcoma. Lancet Oncol. 11:184–192. 2010. View Article : Google Scholar : PubMed/NCBI

25 

Kinsey M, Smith R, Iyer AK, McCabe ER and Lessnick SL: EWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma. Cancer Res. 69:9047–9055. 2009. View Article : Google Scholar : PubMed/NCBI

26 

Tirode F, Laud-Duval K, Prieur A, Delorme B, Charbord P and Delattre O: Mesenchymal stem cell features of Ewing tumors. Cancer Cell. 11:421–429. 2007. View Article : Google Scholar : PubMed/NCBI

27 

Karski EE, McIlvaine E, Segal MR, Krailo M, Grier HE, Granowetter L, Womer RB, Meyers PA, Felgenhauer J, Marina N, et al: Identification of discrete prognostic groups in Ewing sarcoma. Pediatr Blood Cancer. 63:47–53. 2016. View Article : Google Scholar : PubMed/NCBI

28 

Suvà ML, Riggi N, Stehle JC, Baumer K, Tercier S, Joseph JM, Suvà D, Clément V, Provero P, Cironi L, et al: Identification of cancer stem cells in Ewing's sarcoma. Cancer Res. 69:1776–1781. 2009. View Article : Google Scholar : PubMed/NCBI

29 

Riggi N, Suvà ML, De Vito C, Provero P, Stehle JC, Baumer K, Cironi L, Janiszewska M, Petricevic T, Suvà D, et al: EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells. Genes Dev. 24:916–932. 2010. View Article : Google Scholar : PubMed/NCBI

30 

Xu N, Papagiannakopoulos T, Pan G, Thomson JA and Kosik KS: MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell. 137:647–658. 2009. View Article : Google Scholar : PubMed/NCBI

31 

Barta T, Peskova L, Collin J, Montaner D, Neganova I, Armstrong L and Lako M: Brief Report: Inhibition of miR-145 enhances reprogramming of human dermal fibroblasts to induced pluripotent stem cells. Stem Cells. 34:246–251. 2016. View Article : Google Scholar : PubMed/NCBI

32 

Panza A, Votino C, Gentile A, Valvano MR, Colangelo T, Pancione M, Micale L, Merla G, Andriulli A, Sabatino L, et al: Peroxisome proliferator-activated receptor γ-mediated induction of microRNA-145 opposes tumor phenotype in colorectal cancer. Biochim Biophys Acta. 1843:1225–1236. 2014. View Article : Google Scholar : PubMed/NCBI

33 

Wahl J, Bogatyreva L, Boukamp P, Rojewski M, van Valen F, Fiedler J, Hipp N, Debatin KM and Beltinger C: Ewing's sarcoma cells with CD57-associated increase of tumorigenicity and with neural crest-like differentiation capacity. Int J Cancer. 127:1295–1307. 2010. View Article : Google Scholar : PubMed/NCBI

34 

Leuchte K, Altvater B, Hoffschlag S, Potratz J, Meltzer J, Clemens D, Luecke A, Hardes J, Dirksen U, Juergens H, et al: Anchorage-independent growth of Ewing sarcoma cells under serum-free conditions is not associated with stem-cell like phenotype and function. Oncol Rep. 32:845–852. 2014. View Article : Google Scholar : PubMed/NCBI

35 

Scannell CA, Pedersen EA, Mosher JT, Krook MA, Nicholls LA, Wilky BA, Loeb DM and Lawlor ER: LGR5 is expressed by Ewing sarcoma and potentiates Wnt/β-catenin signaling. Front Oncol. 3:812013. View Article : Google Scholar : PubMed/NCBI

36 

Leushacke M and Barker N: Lgr5 and Lgr6 as markers to study adult stem cell roles in self-renewal and cancer. Oncogene. 31:3009–3022. 2012. View Article : Google Scholar : PubMed/NCBI

37 

Yang L, Takimoto T and Fujimoto J: Prognostic model for predicting overall survival in children and adolescents with rhabdomyosarcoma. BMC Cancer. 14:6542014. View Article : Google Scholar : PubMed/NCBI

38 

Marshall AD and Grosveld GC: Alveolar rhabdomyosarcoma - the molecular drivers of PAX3/7-FOXO1-induced tumorigenesis. Skelet Muscle. 2:252012. View Article : Google Scholar : PubMed/NCBI

39 

Ren YX, Finckenstein FG, Abdueva DA, Shahbazian V, Chung B, Weinberg KI, Triche TJ, Shimada H and Anderson MJ: Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations. Cancer Res. 68:6587–6597. 2008. View Article : Google Scholar : PubMed/NCBI

40 

Rubin BP, Nishijo K, Chen HI, Yi X, Schuetze DP, Pal R, Prajapati SI, Abraham J, Arenkiel BR, Chen QR, et al: Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma. Cancer Cell. 19:177–191. 2011. View Article : Google Scholar : PubMed/NCBI

41 

Pressey JG, Haas MC, Pressey CS, Kelly VM, Parker JN, Gillespie GY and Friedman GK: CD133 marks a myogenically primitive subpopulation in rhabdomyosarcoma cell lines that are relatively chemoresistant but sensitive to mutant HSV. Pediatr Blood Cancer. 60:45–52. 2013. View Article : Google Scholar : PubMed/NCBI

42 

Hirotsu M, Setoguchi T, Matsunoshita Y, Sasaki H, Nagao H, Gao H, Sugimura K and Komiya S: Tumour formation by single fibroblast growth factor receptor 3-positive rhabdomyosarcoma-initiating cells. Br J Cancer. 101:2030–2037. 2009. View Article : Google Scholar : PubMed/NCBI

43 

Nakahata K, Uehara S, Nishikawa S, Kawatsu M, Zenitani M, Oue T and Okuyama H: Aldehyde dehydrogenase 1 (ALDH1) is a potential marker for cancer stem cells in embryonal rhabdomyosarcoma. PLoS One. 10:e01254542015. View Article : Google Scholar : PubMed/NCBI

44 

Siegel RL, Miller KD and Jemal A: Cancer statistics, 2015. CA Cancer J Clin. 65:5–29. 2015. View Article : Google Scholar : PubMed/NCBI

45 

Ryan DP, Hong TS and Bardeesy N: Pancreatic adenocarcinoma. N Engl J Med. 371:1039–1049. 2014. View Article : Google Scholar : PubMed/NCBI

46 

Thomas RM, Kim J, Revelo-Penafiel MP, Angel R, Dawson DW and Lowy AM: The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia. Gut. 57:1555–1560. 2008. View Article : Google Scholar : PubMed/NCBI

47 

Krieg A, Riemer JC, Telan LA, Gabbert HE and Knoefel WT: CXCR4− A prognostic and clinicopathological biomarker for pancreatic ductal adenocarcinoma: A meta-analysis. PLoS One. 10:e01301922015. View Article : Google Scholar : PubMed/NCBI

48 

Shen B, Zheng MQ, Lu JW, Jiang Q, Wang TH and Huang XE: CXCL12− CXCR4 promotes proliferation and invasion of pancreatic cancer cells. Asian Pac J Cancer Prev. 14:5403–5408. 2013. View Article : Google Scholar : PubMed/NCBI

49 

Immervoll H, Hoem D, Steffensen OJ, Miletic H and Molven A: Visualization of CD44 and CD133 in normal pancreas and pancreatic ductal adenocarcinomas: Non-overlapping membrane expression in cell populations positive for both markers. J Histochem Cytochem. 59:441–455. 2011. View Article : Google Scholar : PubMed/NCBI

50 

Hou YC, Chao YJ, Tung HL, Wang HC and Shan YS: Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma. Cancer. 120:2766–2777. 2014. View Article : Google Scholar : PubMed/NCBI

51 

Li X, Zhao H, Gu J and Zheng L: Prognostic value of cancer stem cell marker CD133 expression in pancreatic ductal adenocarcinoma (PDAC): A systematic review and meta-analysis. Int J Clin Exp Pathol. 8:12084–12092. 2015.PubMed/NCBI

52 

Singh S, Arcaroli JJ, Orlicky DJ, Chen Y, Messersmith WA, Bagby S, Purkey A, Quackenbush KS, Thompson DC and Vasiliou V: Aldehyde dehydrogenase 1B1 as a modulator of pancreatic adenocarcinoma. Pancreas. 45:117–122. 2016. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Cao J, An Q and Wang L: Pediatric sarcomas (Review) Retraction in /10.3892/ol.2018.7943. Oncol Lett 15: 1397-1402, 2018.
APA
Cao, J., An, Q., & Wang, L. (2018). Pediatric sarcomas (Review) Retraction in /10.3892/ol.2018.7943. Oncology Letters, 15, 1397-1402. https://doi.org/10.3892/ol.2017.7467
MLA
Cao, J., An, Q., Wang, L."Pediatric sarcomas (Review) Retraction in /10.3892/ol.2018.7943". Oncology Letters 15.2 (2018): 1397-1402.
Chicago
Cao, J., An, Q., Wang, L."Pediatric sarcomas (Review) Retraction in /10.3892/ol.2018.7943". Oncology Letters 15, no. 2 (2018): 1397-1402. https://doi.org/10.3892/ol.2017.7467
Copy and paste a formatted citation
x
Spandidos Publications style
Cao J, An Q and Wang L: Pediatric sarcomas (Review) Retraction in /10.3892/ol.2018.7943. Oncol Lett 15: 1397-1402, 2018.
APA
Cao, J., An, Q., & Wang, L. (2018). Pediatric sarcomas (Review) Retraction in /10.3892/ol.2018.7943. Oncology Letters, 15, 1397-1402. https://doi.org/10.3892/ol.2017.7467
MLA
Cao, J., An, Q., Wang, L."Pediatric sarcomas (Review) Retraction in /10.3892/ol.2018.7943". Oncology Letters 15.2 (2018): 1397-1402.
Chicago
Cao, J., An, Q., Wang, L."Pediatric sarcomas (Review) Retraction in /10.3892/ol.2018.7943". Oncology Letters 15, no. 2 (2018): 1397-1402. https://doi.org/10.3892/ol.2017.7467
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