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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2018 Volume 15 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Mitogen-activated protein kinase signaling pathway in oral cancer (Review)

Qian Peng, Zhiyuan Deng, Hao Pan, Liqun Gu, Ousheng Liu, Zhangui Tang
Pages: 1379-1388
Published online on: 24 November 2017

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Review

Patellar metastasis from primary tumor (Review)

Gang Li, Changxing Shan, Ran Sun, Song Liu, Song Chen, Mingzhi Song, Ming Lu
Pages: 1389-1396
Published online on: 23 November 2017

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Article Open Access

Pediatric sarcomas (Review) Retraction in /10.3892/ol.2018.7943

Junhua Cao, Qi An, Lei Wang
Pages: 1397-1402
Published online on: 21 November 2017

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Article Open Access

CXCL5 secreted from adipose tissue‑derived stem cells promotes cancer cell proliferation

Yuying Zhao, Xiaosan Zhang, Hong Zhao, Jingxuan Wang, Qingyuan Zhang
Pages: 1403-1410
Published online on: 05 December 2017

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Article Open Access

Effects of liver cirrhosis on portal vein embolization prior to right hepatectomy in patients with primary liver cancer

Jun‑Hui Sun, Yue‑Lin Zhang, Chun‑Hui Nie, Ju Li, Tan‑Yang Zhou, Guan‑Hui Zhou, Tong‑Yin Zhu, Li‑Ming Chen, Wei‑Lin Wang, Shu‑Sen Zheng
Pages: 1411-1416
Published online on: 05 December 2017

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Article Open Access

The role of cadherin-11 in microcystin-LR-induced migration and invasion in colorectal carcinoma cells

Qiangqiang Zhu, Zhen Wang, Lihua Zhou, Yan Ren, Ying Gong, Wei Qin, Lin Bai, Jun Hu, Ting Wang
Pages: 1417-1422
Published online on: 21 November 2017

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Article Open Access

Piperlongumine induces apoptosis and autophagy in leukemic cells through targeting the PI3K/Akt/mTOR and p38 signaling pathways

Hongfei Wang, Yongqiang Wang, Hongmei Gao, Bing Wang, Lin Dou, Yin Li
Pages: 1423-1428
Published online on: 29 November 2017

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Article Open Access

Prognostic value of SPARCL1 in patients with colorectal cancer

Wei Han, Fang Cao, Wei Ding, Xiao‑Jiao Gao, Fang Chen, Yong‑Wei Hu, Hou‑Zhong Ding
Pages: 1429-1434
Published online on: 05 December 2017

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Article Open Access

MicroRNA-26b suppresses autophagy in breast cancer cells by targeting DRAM1 mRNA, and is downregulated by irradiation Corrigendum in /10.3892/ol.2021.12460

Cuida Meng, Yang Liu, Yannan Shen, Shuchun Liu, Zhicheng Wang, Qingsheng Ye, Hongyang Liu, Xiaodong Liu, Lili Jia
Pages: 1435-1440
Published online on: 21 November 2017

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Article Open Access

The ribosome inhibiting protein riproximin shows antineoplastic activity in experimental pancreatic cancer liver metastasis

Ahmed Murtaja, Ergül Eyol, Jiang Xiaoqi, Martin R. Berger, Hassan Adwan
Pages: 1441-1448
Published online on: 05 December 2017

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Article Open Access

Increased expression of mitochondrial transcription factor A and nuclear respiratory factor‑1 predicts a poor clinical outcome of breast cancer

Wei Gao, Meihong Wu, Ning Wang, Yingyi Zhang, Jing Hua, Gusheng Tang, Yajie Wang
Pages: 1449-1458
Published online on: 24 November 2017

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Article Open Access

Altered capicua transcriptional repressor gene expression exhibits distinct prognostic value for isocitrate dehydrogenase-mutant oligodendroglial tumors

Fuxin Han, Jinsong Zhang, Shanbo Ma, Xiaoyan Chen, Weiping Liu, Xiaosheng He, Zhou Fei, Yangang Wang
Pages: 1459-1468
Published online on: 21 November 2017

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Article Open Access

Utility of bronchial lavage fluids for epithelial growth factor receptor mutation assay in lung cancer patients: Comparison between cell pellets, cell blocks and matching tissue specimens

Shiho Asaka, Akihiko Yoshizawa, Rie Nakata, Tatsuya Negishi, Hiroshi Yamamoto, Takayuki Shiina, Shohei Shigeto, Kazuyuki Matsuda, Yukihiro Kobayashi, Takayuki Honda
Pages: 1469-1474
Published online on: 21 November 2017

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Article Open Access

MicroRNA‑150 inhibitors enhance cell apoptosis of melanoma by targeting PDCD4

Jianji Wan, Jie Yang, Yueshen Huang, Liehua Deng
Pages: 1475-1482
Published online on: 20 November 2017

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Article Open Access

The link between FOXJ1 expression level in bladder carcinoma and tumor recurrence Retraction in /10.3892/ol.2018.8920

Bing Liang, Xinwei He, Donghao Shang, Ye Tian, Zongwen Liu
Pages: 1483-1486
Published online on: 29 November 2017

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Article Open Access

Autophagy activation promotes bevacizumab resistance in glioblastoma by suppressing Akt/mTOR signaling pathway

He Huang, Jian Song, Zheng Liu, Li Pan, Guozheng Xu
Pages: 1487-1494
Published online on: 20 November 2017

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Article Open Access

Sodium butyrate induces senescence and inhibits the invasiveness of glioblastoma cells

Hidemitsu Nakagawa, Satoru Sasagawa, Kazuyuki Itoh
Pages: 1495-1502
Published online on: 05 December 2017

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Article Open Access

Comprehensive characterization of cancer genes in hepatocellular carcinoma genomes

Zhihao Zhang, Liping Xu, Changyu Sun
Pages: 1503-1510
Published online on: 05 December 2017

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Article Open Access

ARK5 promotes invasion and migration in hepatocellular carcinoma cells by regulating epithelial-mesenchymal transition

Zhiyu Ye, Xudong Chen, Xiaogang Chen
Pages: 1511-1516
Published online on: 21 November 2017

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Article Open Access

Oxaliplatin and infliximab synergize to induce regression of colon cancer

Di Huang, Jun Xue, Shuguang Li, Dongdong Yang
Pages: 1517-1522
Published online on: 22 November 2017

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Article Open Access

All-trans retinoic acid inhibits the proliferation of SGC7901 cells by regulating caveolin-1 localization via the ERK/MAPK signaling pathway

Sumei Zhang, Rui Shi, Shaolong Chen, Xiang Wei, Qing Zhou, Yuan Wang
Pages: 1523-1528
Published online on: 29 November 2017

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Article Open Access

Co‑existence of benign gynecological tumors with endometriosis in a group of 1,000 women

Charoula Matalliotaki, Michail Matalliotakis, Panagiotis Ieromonachou, George N. Goulielmos, Maria I. Zervou, Aggelos Laliotis, Demetrios A. Spandidos, Aydin Arici, Ioannis Matalliotakis
Pages: 1529-1532
Published online on: 20 November 2017

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Article Open Access

The relationship between cervical precancerous lesion galectin-3 and p27 protein expression and clinical prognosis

Jianting Ma, Xingguang Zhang, Gang He, Chunlin Yang
Pages: 1533-1536
Published online on: 29 November 2017

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Article Open Access

BmK CT enhances the sensitivity of temozolomide-induced apoptosis of malignant glioma U251 cells in vitro through blocking the AKT signaling pathway

Jun Du, Ruijie Wang, Litian Yin, Yuejun Fu, Yuqing Cai, Zhiyun Zhang, Aihua Liang
Pages: 1537-1544
Published online on: 24 November 2017

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Article Open Access

Effects of flurbiprofen on serum level of interleukin-6, prostacyclin and corticosteroid A2 in patients with bone metastases of cancer

Yanwei Yin, Yusheng Yi, Junmin Yu, Xiuming Sun, Chuansheng Liu, Fenghe Xu
Pages: 1545-1548
Published online on: 23 November 2017

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Article Open Access

Family with sequence similarity 83, member B is a predictor of poor prognosis and a potential therapeutic target for lung adenocarcinoma expressing wild‑type epidermal growth factor receptor

Takumi Yamaura, Junji Ezaki, Naoyuki Okabe, Hironori Takagi, Yuki Ozaki, Takuya Inoue, Yuzuru Watanabe, Mitsuro Fukuhara, Satoshi Muto, Yuki Matsumura, Takeo Hasegawa, Mika Hoshino, Jun Osugi, Yutaka Shio, Satoshi Waguri, Hirosumi Tamura, Jun‑Ichi Imai, Emi Ito, Yuka Yanagisawa, Reiko Honma, Shinya Watanabe, Hiroyuki Suzuki
Pages: 1549-1558
Published online on: 05 December 2017

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Article Open Access

Modulation of G2/M cell cycle arrest and apoptosis by luteolin in human colon cancer cells and xenografts

Zhicheng Chen, Bo Zhang, Feng Gao, Renjie Shi
Pages: 1559-1565
Published online on: 23 November 2017

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Article Open Access

Bufadienolides induce p53-mediated apoptosis in esophageal squamous cell carcinoma cells in vitro and in vivo

Shaohuan Lin, Junhong Lv, Panli Peng, Changqing Cai, Jianming Deng, Haihong Deng, Xuejun Li, Xinyue Tang
Pages: 1566-1572
Published online on: 21 November 2017

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Article Open Access

Platelet-derived growth factor-D promotes colorectal cancer cell migration, invasion and proliferation by regulating Notch1 and matrix metalloproteinase-9

Bin Jiang, Jinhuang Chen, Wenzheng Yuan, Jintong Ji, Zhengyi Liu, Liang Wu, Qiang Tang, Xiaogang Shu
Pages: 1573-1579
Published online on: 05 December 2017

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Article Open Access

Intracellular IL‑4 and IFN‑γ expression in iNKT cells from patients with chronic lymphocytic leukemia

Agnieszka Bojarska‑Junak, Małgorzata Waldowska, Justyna Woś, Sylwia Chocholska, Iwona Hus, Waldemar Tomczak, Michał Dzik, Marek Hus, Jacek Roliński
Pages: 1580-1590
Published online on: 24 November 2017

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Article Open Access

Celastrus orbiculatus extracts induce cell cycle arrest and apoptosis in human esophageal squamous carcinoma ECA-109 cells in vitro via the PI3K/AKT/mTOR signaling pathway

Feng Jin, Guang Zhu, Dan Li, Tengyang Ni, Xiaojun Dai, Haibo Wang, Jun Feng, Yayun Qian, Lin Yang, Shiyu Guo, Tadashi Hisamitsu, Yanqing Liu
Pages: 1591-1599
Published online on: 21 November 2017

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Article Open Access

Promoter methylation of RB1, P15, P16, and MGMT and their impact on the clinical course of pilocytic astrocytomas

Christoph Sippl, Steffi Urbschat, Yoo Jin Kim, Sebastian Senger, Joachim Oertel, Ralf Ketter
Pages: 1600-1606
Published online on: 24 November 2017

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Article Open Access

High-fat diet‑induced adipokine and cytokine alterations promote the progression of prostate cancer in vivo and in vitro

Meng‑Bo Hu, Hua Xu, Wen‑Hui Zhu, Pei‑De Bai, Ji‑Meng Hu, Tian Yang, Hao‑Wen Jiang, Qiang Ding
Pages: 1607-1615
Published online on: 21 November 2017

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Article Open Access

Correlation between TAP detection and common digestive tract precancerous lesions

Changqing Sun, Fang Deng, Lingjun Meng, Guohua Chen
Pages: 1616-1620
Published online on: 28 November 2017

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Article Open Access

miR‑125b regulates the drug‑resistance of breast cancer cells to doxorubicin by targeting HAX‑1

Guinv Hu, Xiaokang Zhao, Jiang Wang, Liting Lv, Chaoqun Wang, Liang Feng, Liangqiong Shen, Weili Ren
Pages: 1621-1629
Published online on: 23 November 2017

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Article Open Access

Silencing of suppressor of cytokine signaling 1 enhances the immunological effect of mucin 1-calreticulin-primed 4T1 cell-treated dendritic cells in breast cancer treatment

Song Qin, Zhipeng Gao, Yu Liu, Changbai Liu, Jun Wang, Li Li Zou
Pages: 1630-1638
Published online on: 23 November 2017

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Article Open Access

Comparison of the expression of TGF‑β1, E‑cadherin, N‑cadherin, TP53, RB1CC1 and HIF‑1α in oral squamous cell carcinoma and lymph node metastases of humans and mice

Mengzhu Guo, Yun Mu, Dahai Yu, Jing Li, Fengqiang Chen, Baosheng Wei, Shichang Bi, Jia Yu, Feixin Liang
Pages: 1639-1645
Published online on: 21 November 2017

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Article Open Access

Effects of HPV16E6 transfection on the biological behavior of Eca109 and Eca9706 cells Corrigendum in /10.3892/ol.2021.12552

Xin‑Dan Kang, Yong Zheng, Wei‑Gang Chen, Min Cheng, Di Zhang
Pages: 1646-1654
Published online on: 22 November 2017

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Article Open Access

Bioinformatic analysis of gene expression profiles of pituitary gonadotroph adenomas

Ziming Hou, Jun Yang, Gang Wang, Changjiang Wang, Hongbing Zhang
Pages: 1655-1663
Published online on: 30 November 2017

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Article Open Access

Pre‑treatment neutrophil‑to‑lymphocyte ratio predicts survival in patients with laryngeal cancer

Jintao Du, Jifeng Liu, Xinyuan Zhang, Xiaoting Chen, Rong Yu, Deying Gu, Jian Zou, Yafeng Liu, Shixi Liu
Pages: 1664-1672
Published online on: 29 November 2017

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Article Open Access

MiR‑370 promotes apoptosis in colon cancer by directly targeting MDM4

Xiaogang Shen, Xiaofei Zuo, Wenjin Zhang, Yifeng Bai, Xianpeng Qin, Nengyi Hou
Pages: 1673-1679
Published online on: 05 December 2017

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Article Open Access

Identification of common key genes in breast, lung and prostate cancer and exploration of their heterogeneous expression

Richa K. Makhijani, Shital A. Raut, Hemant J. Purohit
Pages: 1680-1690
Published online on: 30 November 2017

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Article Open Access

Effect of matrine against breast cancer by downregulating the vascular endothelial growth factor via the Wnt/β‑catenin pathway

Xu Xiao, Man Ao, Fan Xu, Xiao Li, Jiuli Hu, Ying Wang, Daixiao Li, Xiaoqin Zhu, Chunlan Xin, Wenda Shi
Pages: 1691-1697
Published online on: 05 December 2017

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Article Open Access

Diagnostic evaluations of ultrasound and magnetic resonance imaging in mammary duct ectasia and breast cancer

Lei Song, Liang Li, Bin Liu, Dexin Yu, Fengguo Sun, Mingming Guo, Zhengmin Ruan, Feixue Zhang
Pages: 1698-1706
Published online on: 05 December 2017

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Article Open Access

High frequency and prognostic value of MYD88 L265P mutation in diffuse large B‑cell lymphoma with R‑CHOP treatment

Sisi Yu, Huaichao Luo, Meiling Pan, Luis Angel Palomino, Xiaoyu Song, Ping Wu, Jian‑Ming Huang, Zhihui Zhang
Pages: 1707-1715
Published online on: 22 November 2017

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Article Open Access

Logistic regression analysis of risk factors for postoperative recurrence of spinal tumors and analysis of prognostic factors

Shanyong Zhang, Lili Yang, Chuangang Peng, Minfei Wu
Pages: 1716-1722
Published online on: 04 December 2017

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Article Open Access

miR-93 enhances cell proliferation by directly targeting CDKN1A in nasopharyngeal carcinoma

Yingyao Zhang, Zhina Xu
Pages: 1723-1727
Published online on: 24 November 2017

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Article Open Access

Cytotoxic effect of Efavirenz in BxPC‑3 pancreatic cancer cells is based on oxidative stress and is synergistic with ionizing radiation

Markus Hecht, Thomas Harrer, Verena Körber, Eric O. Sarpong, Fabian Moser, Nora Fiebig, Manuela Schwegler, Michael Stürzl, Rainer Fietkau, Luitpold V. Distel
Pages: 1728-1736
Published online on: 05 December 2017

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Article Open Access

A hederagenin saponin isolated from Clematis ganpiniana induces apoptosis in breast cancer cells via the mitochondrial pathway

Lin Cheng, Liang Shi, Jing Wu, Xujie Zhou, Xiaoxia Li, Xi Sun, Lei Zhu, Tian‑Song Xia, Qiang Ding
Pages: 1737-1743
Published online on: 27 November 2017

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Article Open Access

Characterization of the T‑cell receptor repertoire by deep T cell receptor sequencing in tissues from patients with prostate cancer

Song Liu, Weibing Pan, Zhiqiang Cheng, Guoping Sun, Peng Zhu, Franky Chan, Yunlong Hu, Xinzhou Zhang, Yong Dai
Pages: 1744-1752
Published online on: 23 November 2017

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Article Open Access

Expression of miR-590 in lung cancer and its correlation with prognosis

Zhifeng Ma, Yaoqin Wang, Binjun He, Jian Cui, Chu Zhang, Haiyong Wang, Weizhong Feng, Bin Wang, Desheng Wei, Yuanlin Wu, Yong Zeng, Guangmao Yu
Pages: 1753-1757
Published online on: 28 November 2017

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Article

Mechanisms for DNA‑damaging agent‑induced inactivation of ErbB2 and ErbB3 via the ERK and p38 signaling pathways

Chul Min Park, Yuki Kawasaki, Alaa Refaat, Hiroaki Sakurai
Pages: 1758-1762
Published online on: 05 December 2017

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Article

Regulator of G‑protein signaling 5 enhances portal vein invasion in hepatocellular carcinoma

Yumi Umeno, Sachiko Ogasawara, Jun Akiba, Satoshi Hattori, Hironori Kusano, Osamu Nakashima, Hironori Koga, Takuji Torimura, Ryoji Yamakawa, Hirohisa Yano
Pages: 1763-1770
Published online on: 23 November 2017

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Article

Mechanisms by which CXCR4/CXCL12 cause metastatic behavior in pancreatic cancer

Jianbo Zhang, Chengxin Liu, Xinkai Mo, Huan Shi, Sheng Li
Pages: 1771-1776
Published online on: 05 December 2017

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Article

Antitumor effects of matrine on cancer stem like cells isolated from the human liver cancer SMMC‑7721 cell line

Yong Wang, Yahui Liu, Jianshuai Jiang, Hanbin Cui
Pages: 1777-1782
Published online on: 05 December 2017

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Article

Soluble HER3 predicts survival in bladder cancer patients

Ashfaque A. Memon, Stephen C. Gilliver, Michael Borre, Jan Sundquist, Kristina Sundquist, Ebba Nexo, Boe S. Sorensen
Pages: 1783-1788
Published online on: 22 November 2017

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Article

Piperlongumine inhibits cancer stem cell properties and regulates multiple malignant phenotypes in oral cancer

Yin‑Ju Chen, Chia‑Chun Kuo, Lai‑Lei Ting, Long‑Sheng Lu, Ya‑Ching Lu, Ann‑Joy Cheng, Yun‑Tien Lin, Chien‑Ho Chen, Jo‑Ting Tsai, Jeng‑Fong Chiou
Pages: 1789-1798
Published online on: 24 November 2017

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Article

A retrospective, single‑center cohort study on 65 patients with primary retroperitoneal liposarcoma

Yi‑Xi Wu, Jun‑Yan Liu, Jia‑Jia Liu, Peng Yan, Bo Tang, You‑Hong Cui, Yong‑Liang Zhao, Yan Shi, Ying‑Xue Hao, Pei‑Wu Yu, Feng Qian
Pages: 1799-1810
Published online on: 05 December 2017

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Article

Metformin synergizes with rapamycin to inhibit the growth of pancreatic cancer in vitro and in vivo

Jia‑Wei Zhang, Fan Zhao, Qing Sun
Pages: 1811-1816
Published online on: 20 November 2017

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Article

Progesterone impairs Herceptin effect on breast cancer cells

Kamila Kitowska, Agnieszka Kowalska, Magdalena Mieszkowska, Dominika Piasecka, Andrzej C. Skladanowski, Hanna M. Romanska, Rafal Sadej
Pages: 1817-1822
Published online on: 27 November 2017

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Article

A multidisciplinary group for prostate cancer management: A single institution experience

Antonella Colasante, Antonietta Augurio, Raffaella Basilico, Antonio Raffaele Cotroneo, Maria B. Di Sciascio, Giuseppe Gaspari, Domenico Genovesi, Jamara Giampietro, Romina Iantorno, Antonio Marchetti, Clara Natoli, Antonello Nuzzo, Floriana Ottaviani, Paolo Pompa, Pietro Castellan, Raffaele Tenaglia, Annamaria Vinciguerra
Pages: 1823-1828
Published online on: 30 November 2017

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Article

Microarray pathway analysis indicated that mitogen-activated protein kinase/extracellular signal-regulated kinase and insulin growth factor 1 signaling pathways were inhibited by small interfering RNA against AT‑rich interactive domain 1A in endometrial cancer

Ye Yang, Wei Bao, Zhengyu Sang, Yongbing Yang, Meng Lu, Xiaowei Xi
Pages: 1829-1838
Published online on: 24 November 2017

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Article

Clinical significance of BRAFV600E mutation in circulating tumor DNA in Chinese patients with melanoma

Huan Tang, Yan Kong, Lu Si, Chuanliang Cui, Xinan Sheng, Zhihong Chi, Jie Dai, Sifan Yu, Meng Ma, Xiaowen Wu, Jiayi Yu, Tianxiao Xu, Huan Yu, Junya Yan, Jun Guo
Pages: 1839-1844
Published online on: 05 December 2017

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Article

18F-fluorodeoxyglucose positron emission computed tomography for monitoring tumor response in esophageal carcinoma treated with concurrent chemoradiotherapy

Peiliang Zhang, Zengyun Li, Dongqing Wang, Fuling Ma, Ran Zhang, Wanhua Liang, Mingping Sun, Zheng Fu, Xiaorong Sun
Pages: 1845-1852
Published online on: 05 December 2017

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Article

Prognostic relevance of FGFR2 expression in stage II/III gastric cancer with curative resection and S‑1 chemotherapy

Kei Hosoda, Keishi Yamashita, Hideki Ushiku, Akira Ema, Hiromitsu Moriya, Hiroaki Mieno, Marie Washio, Masahiko Watanabe
Pages: 1853-1860
Published online on: 05 December 2017

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Article

lncRNA FAM83H‑AS1 is associated with the prognosis of colorectal carcinoma and promotes cell proliferation by targeting the Notch signaling pathway

Song Lu, Wei Dong, Pei Zhao, Zhenjun Liu
Pages: 1861-1868
Published online on: 05 December 2017

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Article

Licochalcone A inhibits PI3K/Akt/mTOR signaling pathway activation and promotes autophagy in breast cancer cells

Lei Xue, Wei‑Jie Zhang, Qing‑Xia Fan, Liu‑Xing Wang
Pages: 1869-1873
Published online on: 21 November 2017

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Article

Endostatin reverses immunosuppression of the tumor microenvironment in lung carcinoma

Xiaolin Liu, Weiwei Nie, Qi Xie, Guoling Chen, Xingyu Li, Yanrui Jia, Beibei Yin, Xun Qu, Yan Li, Jing Liang
Pages: 1874-1880
Published online on: 21 November 2017

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Article

Low-dose paclitaxel downregulates MYC proto-oncogene bHLH transcription factor expression in colorectal carcinoma cells

Wenjing Li, Wanyun Zhu, Chaoxiang Lv, Hao Qu, Kaixiang Xu, Honghui Li, Haifeng Li, Yiming Du, Guangming Liu, Yunyue Wang, Hong‑Jiang Wei, Hong‑Ye Zhao
Pages: 1881-1887
Published online on: 05 December 2017

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Article

Association between expression of nuclear receptor co‑activator 5 protein and prognosis in postoperative patients with osteosarcoma

Ya Wu, Jian Wu, Qi‑Rong Dong, Nai‑Zhou Guo
Pages: 1888-1892
Published online on: 05 December 2017

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Article

PI3K/AKT/Afadin signaling pathway contributes to pathological vascularization in glioblastomas

Xuan Zhai, Yingliang Li, Ping Liang, Lusheng Li, Yudong Zhou, Weidan Zhang, Difei Wang, Guanghui Wei
Pages: 1893-1899
Published online on: 21 November 2017

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Article

AXL is a marker for epithelial‑mesenchymal transition in esophageal squamous cell carcinoma

Guoan Zhang, Xia Kong, Meng Wang, Hongli Zhao, Sha Han, Ronghang Hu, Jian Huang, Wen Cui
Pages: 1900-1906
Published online on: 20 November 2017

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Article

Combined small cell carcinoma with giant cell carcinoma component of the lung: A case successfully diagnosed by computed tomography‑guided fine‑needle aspiration cytology

Yusuke Ebisu, Mitsuaki Ishida, Tomohito Saito, Tomohiro Murakawa, Yoshiko Uemura, Koji Tsuta
Pages: 1907-1911
Published online on: 20 November 2017

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Article

Severe acute toxicity following gemcitabine administration: A report of four cases with cytidine deaminase polymorphisms evaluation

Beata Hryciuk, Bartosz Szymanowski, Anna Romanowska, Ewa Salt, Bartosz Wasąg, Bartłomiej Grala, Jacek Jassem, Renata Duchnowska
Pages: 1912-1916
Published online on: 22 November 2017

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Article

MEG3 inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells

Yao Shi, Chen Lv, Li Shi, Guanjun Tu
Pages: 1917-1923
Published online on: 21 November 2017

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Article

lncRNA SNHG5 is associated with poor prognosis of bladder cancer and promotes bladder cancer cell proliferation through targeting p27

Zhipeng Ma, Senyao Xue, Bi Zeng, Daoxian Qiu
Pages: 1924-1930
Published online on: 05 December 2017

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Article

Effects of harmaline on cell growth of human liver cancer through the p53/p21 and Fas/FasL signaling pathways

Bin Xu, Minpeng Li, Yuan Yu, Jun He, Siqin Hu, Meng Pan, Shifeng Lu, Ke Liao, Zhuang Pan, Yanxun Zhou, Jiye Zhu
Pages: 1931-1936
Published online on: 28 November 2017

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Article

Bone marrow stromal cells enhance the survival of chronic lymphocytic leukemia cells by regulating HES‑1 gene expression and H3K27me3 demethylation

Zhenshu Xu, Donglian Xiong, Jushun Zhang, Jingyan Zhang, Xiuli Chen, Zhizhe Chen, Rong Zhan
Pages: 1937-1942
Published online on: 21 November 2017

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Article

Down‑expression of poly(ADP‑ribose) polymerase in p53‑regulated pancreatic cancer cells

Zhenyu Hou, Yunfeng Cui, Huizhi Xing, Xiaoyan Mu
Pages: 1943-1948
Published online on: 29 November 2017

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Article

Dihydroartemisinin increases apoptosis of colon cancer cells through targeting Janus kinase 2/signal transducer and activator of transcription 3 signaling

Dongsheng Wang, Bei Zhong, Yu Li, Xiaodong Liu
Pages: 1949-1954
Published online on: 29 November 2017

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Article

Intra‑arterial interventional therapy for inoperable local advanced breast cancer: A retrospective study

Jing Ma, Jin Song, Hai Chen, Cibo Fan, Jiaqi Xie, Xiaodong Qi
Pages: 1955-1962
Published online on: 30 November 2017

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Article

Folate deficiency and aberrant DNA methylation and expression of FHIT gene were associated with cervical pathogenesis

Qiaoling Li, Ling Ding, Nan Jing, Chunliang Liu, Zuokai Yang, Fang Chen, Lifang Hou, Jintao Wang
Pages: 1963-1972
Published online on: 22 November 2017

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Article

Cytotoxic action of methylquercetins in human lung adenocarcinoma cells

Katrin Sak, Helen Lust, Marju Kase, Jana Jaal
Pages: 1973-1978
Published online on: 21 November 2017

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Article

ABT‑737 and pictilisib synergistically enhance pitavastatin‑induced apoptosis in ovarian cancer cells

Elizabeth De Wolf, Christopher De Wolf, Alan Richardson
Pages: 1979-1984
Published online on: 05 December 2017

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Article

Synergistic inhibition of colon cancer cell growth by a combination of atorvastatin and phloretin

Mo Zhou, Jinkai Zheng, Jinfeng Bi, Xinye Wu, Jian Lyu, Kun Gao
Pages: 1985-1992
Published online on: 23 November 2017

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Article

Preclinical study on hypoxic radiosensitizing effects of glycididazole in comparison with those of doranidazole in vitro and in vivo

Hironobu Yasui, Nobuo Kubota, Junko Nishizumi, Yuri Sakai, Tohru Yamamori, Osamu Inanami
Pages: 1993-1998
Published online on: 23 November 2017

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Article

Oridonin increases anticancer effects of lentinan in HepG2 human hepatoblastoma cells

Zhiqiang Sun, Qinghe Han, Liwei Duan, Qinghai Yuan, Hui Wang
Pages: 1999-2005
Published online on: 24 November 2017

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Article

Reversible growth arrest of 3D tumor spheroids stored in oxygen absorber-induced anoxia

Aurélie Gomes, Matthieu Defaux, Riwanon Michel Lemee, Valérie Lobjois, Bernard Ducommun
Pages: 2006-2009
Published online on: 21 November 2017

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Article

Role of prolactin/adenoma maximum diameter and prolactin/adenoma volume in the differential diagnosis of prolactinomas and other types of pituitary adenomas

Yinxing Huang, Chenyu Ding, Fangfang Zhang, Deyong Xiao, Lin Zhao, Shousen Wang
Pages: 2010-2016
Published online on: 21 November 2017

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Article

Characterization of cluster of differentiation 47 expression and its potential as a therapeutic target in esophageal squamous cell cancer

Chun‑Lin Zhao, Shuang Yu, Shu‑Hui Wang, Shi‑Gang Li, Zhi‑Ju Wang, Sheng‑Na Han
Pages: 2017-2023
Published online on: 20 November 2017

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Article

Chloroquine exerts antitumor effects on NB4 acute promyelocytic leukemia cells and functions synergistically with arsenic trioxide

Shousheng Liu, Xiuyu Cai, Liangping Xia, Chang Jiang, Ping Chen, Xiaopai Wang, Bei Zhang, Hong Yun Zhao
Pages: 2024-2030
Published online on: 24 November 2017

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Review

Surface markers of liver cancer stem cells and innovative targeted-therapy strategies for HCC (Review)

Lige Qiu, Hailiang Li, Sirui Fu, Xiaofang Chen, Ligong Lu
Pages: 2039-2048
Published online on: 08 December 2017

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Review

Epigenetic actions of environmental factors and promising drugs for cancer therapy (Review)

Zhong‑Tian Bai, Bing Bai, Jun Zhu, Cui‑Xia Di, Xun Li, Wen‑Ce Zhou
Pages: 2049-2056
Published online on: 13 December 2017

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Article Open Access

Transcriptome profiling of cancer tissues in Chinese patients with gastric cancer by high-throughput sequencing

Peiying Tian, Chunli Liang
Pages: 2057-2064
Published online on: 08 December 2017

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Article Open Access

Upregulated solute carrier family 37 member 1 in colorectal cancer is associated with poor patient outcome and metastasis

Daiki Kikuchi, Motonobu Saito, Katsuharu Saito, Yohei Watanabe, Yoshiko Matsumoto, Yasuyuki Kanke, Hisashi Onozawa, Suguru Hayase, Wataru Sakamoto, Teruhide Ishigame, Tomoyuki Momma, Shinji Ohki, Seiichi Takenoshita
Pages: 2065-2072
Published online on: 08 December 2017

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Article Open Access

High expression of RACK1 is associated with poor prognosis in patients with pancreatic ductal adenocarcinoma

Hailin Han, Dongmei Wang, Maowu Yang, Shenhao Wang
Pages: 2073-2078
Published online on: 06 December 2017

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Case Report Open Access

Extranodal presentation of Hodgkin's lymphoma of the sternum: A case report and review of the literature

Yan Li, You Qin, Liduan Zheng, Hong Liu
Pages: 2079-2084
Published online on: 07 December 2017

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Article Open Access

Fyn knockdown inhibits migration and invasion in cholangiocarcinoma through the activated AMPK/mTOR signaling pathway

Shao‑Cheng Lyu, Dong‑Dong Han, Xian‑Liang Li, Jun Ma, Qiao Wu, Hong‑Meng Dong, Chun Bai, Qiang He
Pages: 2085-2090
Published online on: 07 December 2017

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Article Open Access

Application values of 3.0T magnetic resonance diffusion weighted imaging for distinguishing liver malignant tumors and benign lesions

Ruibin Li, Guangyao Wu, Rui Wang
Pages: 2091-2096
Published online on: 08 December 2017

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Article Open Access

Novel betulin derivative induces anti-proliferative activity by G2/M phase cell cycle arrest and apoptosis in Huh7 cells

Zhen‑Jian Zhuo, Min‑Jie Xiao, Hui‑Ran Lin, Jing Luo, Tao Wang
Pages: 2097-2104
Published online on: 08 December 2017

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Article Open Access

Notch signaling via regulation of RB and p‑AKT but not PIK3CG contributes to MIA PaCa‑2 cell growth and migration to affect pancreatic carcinogenesis

Shubing Zhang, Jingjiang Liu, Keli Xu, Zhijian Li
Pages: 2105-2110
Published online on: 08 December 2017

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p68 prompts the epithelial‑mesenchymal transition in cervical cancer cells by transcriptionally activating the TGF‑β1 signaling pathway Retraction in /10.3892/ol.2024.14708

Ming‑Yi Li, Jin‑Quan Liu, Dong‑Ping Chen, Zhou‑Yu Li, Bin Qi, Wen‑Jing Yin, Lu He
Pages: 2111-2116
Published online on: 08 December 2017

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Article Open Access

Long non‑coding RNA MALAT‑1 contributes to maintenance of stem cell‑like phenotypes in breast cancer cells Retraction in /10.3892/ol.2024.14292

Linghuan Zeng, Ying Cen, Junjie Chen
Pages: 2117-2122
Published online on: 08 December 2017

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Article

Immunohistochemical CD73 expression status in gastrointestinal neuroendocrine neoplasms: A retrospective study of 136 patients

Kohei Ono, Eisuke Shiozawa, Nobuyuki Ohike, Tomonori Fujii, Hideki Shibata, Tetsuya Kitajima, Koichiro Fujimasa, Naoko Okamoto, Yukiko Kawaguchi, Tasuku Nagumo, Sakiko Tazawa, Mayumi Homma, Toshiko Yamochi‑Onizuka, Tomoko Norose, Hitoshi Yoshida, Masahiko Murakami, Gensyu Tate, Masafumi Takimoto
Pages: 2123-2130
Published online on: 08 December 2017

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Article Open Access

Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer

Xueping Quan, Hongjun Gao, Zhikuan Wang, Jie Li, Wentao Zhao, Wei Liang, Qiang Yu, Dongliang Guo, Zhanping Hao, Jingxin Liu
Pages: 2131-2138
Published online on: 14 December 2017

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Article Open Access

The association between differentially expressed micro RNAs in breast cancer cell lines and the micro RNA‑205 gene polymorphism in breast cancer tissue

Jingcheng Zhang, Bin Wei, Huixian Hu, Fanrong Liu, Yan Tu, Fang He
Pages: 2139-2146
Published online on: 08 December 2017

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Article Open Access

Knockdown of Arf6 increases drug sensitivity and inhibits proliferation, migration and invasion in gastric cancer SGC‑7901 cells

Junlan Qiu, Liang Tao, Qiang Wei, Pingyang Zhang
Pages: 2147-2152
Published online on: 08 December 2017

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Article Open Access

Role of serine/threonine kinase 33 methylation in colorectal cancer and its clinical significance

Ming‑Di Yin, Si‑Ping Ma, Fang Liu, Yu‑Ze Chen
Pages: 2153-2160
Published online on: 14 December 2017

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Characterization and prognostic significance of mortalin, Bcl‑2 and Bax in intrahepatic cholangiocarcinoma

Qiang Kang, Hao Zou, Xuan Yang, Jia‑Bin Cai, Li‑Xin Liu, Nan Xie, Lian‑Min Wang, Yue‑Hua Li, Xiao‑Wen Zhang
Pages: 2161-2168
Published online on: 08 December 2017

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Article Open Access

Correlation between circulating tumor cells and D-D and platelet in patients with pulmonary malignancies

Lijun Yang, Hai Dong, Zixuan Li, Yongyue Pan, La Qu, Zhiwen Tan
Pages: 2169-2172
Published online on: 12 December 2017

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Association of abnormal glucose metabolism and insulin resistance in patients with atypical and typical endometrial cancer

Yongjing Lai, Chuanying Sun
Pages: 2173-2178
Published online on: 12 December 2017

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Article Open Access

Long-term outcomes of patients with soft tissue sarcoma of the chest wall: Analysis of the prognostic significance of microscopic margins

Kamran Harati, Jonas Kolbenschlag, Jens Bohm, Hiltrud Niggemann, Hamid Joneidi‑Jafari, Ingo Stricker, Marcus Lehnhardt, Adrien Daigeler
Pages: 2179-2187
Published online on: 14 December 2017

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Enhanced expression of KIF4A in colorectal cancer is associated with lymph node metastasis

Yoshiko Matsumoto, Motonobu Saito, Katsuharu Saito, Yasuyuki Kanke, Yohei Watanabe, Hisashi Onozawa, Suguru Hayase, Wataru Sakamoto, Teruhide Ishigame, Tomoyuki Momma, Kensuke Kumamoto, Shinji Ohki, Seiichi Takenoshita
Pages: 2188-2194
Published online on: 08 December 2017

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BRAF V600E mutation is a predictive indicator of upfront chemotherapy for stage IV colorectal cancer

Tatsuya Morikawa, Ryo Inada, Takeshi Nagasaka, Yoshiko Mori, Hiroyuki Kishimoto, Takashi Kawai, Yuzo Umeda, Hideyuki Mishima, Ajay Goel, Toshiyoshi Fujiwara
Pages: 2195-2201
Published online on: 08 December 2017

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PAK5 overexpression is associated with lung metastasis in osteosarcoma

Kun Han, Yan Zhou, Kuo‑Fu Tseng, Haiyan Hu, Kunpeng Li, Yaling Wang, Zhihua Gan, Shuchen Lin, Yongning Sun, Daliu Min
Pages: 2202-2210
Published online on: 07 December 2017

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Article Open Access

Upregulation of pyruvate kinase M2 expression by fatty acid synthase contributes to gemcitabine resistance in pancreatic cancer

Shenghua Tian, Pingping Li, Shi Sheng, Xin Jin
Pages: 2211-2217
Published online on: 13 December 2017

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Oxibendazole inhibits prostate cancer cell growth

Qiaoli Chen, Yuhua Li, Xiaoyu Zhou, Runsheng Li
Pages: 2218-2226
Published online on: 11 December 2017

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Vernodalol mediates antitumor effects in acute promyelocytic leukemia cells

Wenjun Wu, Xiaoyan Han, Cai Wu, Guoqing Wei, Gaofeng Zheng, Yi Li, Yang Yang, Li Yang, Donghua He, Yi Zhao, Zhen Cai
Pages: 2227-2235
Published online on: 07 December 2017

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Article Open Access

Increased expression of hepcidin and associated upregulation of JAK/STAT3 signaling in human gastric cancer

Erdong Zuo, Ye Lu, Min Yan, Xiangtao Pan, Xu Cheng
Pages: 2236-2244
Published online on: 08 December 2017

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Neuropilin-1 promotes primary liver cancer progression by potentiating the activity of hepatic stellate cells

Zhi‑Chao Xu, Hao‑Xin Shen, Chen Chen, Li Ma, Wen‑Zhi Li, Lin Wang, Zhi‑Min Geng
Pages: 2245-2251
Published online on: 07 December 2017

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Article Open Access

Quercetin reverses the doxorubicin resistance of prostate cancer cells by downregulating the expression of c‑met

Yan Shu, Bo Xie, Zhen Liang, Jing Chen
Pages: 2252-2258
Published online on: 08 December 2017

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Article Open Access

PD‑L1 expression is associated with p16INK4A expression in non‑oropharyngeal head and neck squamous cell carcinoma

San‑Chi Chen, Peter Mu‑Hsin Chang, Hsiao‑Jung Wang, Shyh‑Kuan Tai, Pen‑Yuan Chu, Muh‑Hwa Yang
Pages: 2259-2265
Published online on: 08 December 2017

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Article Open Access

The hepatoprotective role of reduced glutathione and its underlying mechanism in oxaliplatin-induced acute liver injury

Youzhi Lin, Yongqiang Li, Xiaohua Hu, Zhihui Liu, Jun Chen, Yulei Lu, Juan Liu, Sina Liao, Yumei Zhang, Rong Liang, Yan Lin, Qian Li, Caoyong Liang, Chunling Yuan, Xiaoli Liao
Pages: 2266-2272
Published online on: 12 December 2017

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Article Open Access

Effects of disodium cantharidinate on dendritic cells of patients with bladder carcinoma

Guang-Hui Zang, Rui Li, Rong-Sheng Zhou, Lin Hao, Hou-Guang He, Wen-Da Zhang, Yang Dong, Cong-Hui Han
Pages: 2273-2277
Published online on: 12 December 2017

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Article Open Access

Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions

Francisco Israel Torres‑Rojas, Luz del Carmen Alarcón‑Romero, Marco Antonio Leyva‑Vázquez, Julio Ortiz‑Ortiz, Miguel Ángel Mendoza‑Catalán, Daniel Hernández‑Sotelo, Oscar Del Moral‑Hernández, Hugo Alberto Rodríguez‑Ruiz, Dinorah Leyva‑Illades, Eugenia Flores-Alfaro, Berenice Illades‑Aguiar
Pages: 2278-2286
Published online on: 13 December 2017

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Article Open Access

β‑catenin, leucine-rich repeat-containing G protein-coupled receptor 5 and GATA-binding factor 6 are associated with the normal mucosa‑adenoma‑adenocarcinoma sequence of colorectal tumorigenesis

Bin Yang, Liang Mao, Yan Li, Qia Li, Xioli Li, Yunjing Zhang, Zhenhua Zhai
Pages: 2287-2295
Published online on: 08 December 2017

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Article Open Access

Prognostic value and functional role of ROCK2 in pediatric Ewing sarcoma

Gabriela Maciel Vieira, Gabriela Molinari Roberto, Régia Caroline Lira, Edgard Eduard Engel, Luiz Gonzaga Tone, María Sol Brassesco
Pages: 2296-2304
Published online on: 08 December 2017

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Article Open Access

Genetic characterization and in vitro activity of antimicrobial combinations of multidrug-resistant Acinetobacter baumannii from a general hospital in China

Fang Chen, Ling Wang, Min Wang, Yixin Xie, Xiaomeng Xia, Xianping Li, Yanhua Liu, Wei Cao, Tingting Zhang, Pengling Li, Min Yang
Pages: 2305-2315
Published online on: 13 December 2017

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Article Open Access

Identification of metabolism-associated genes and pathways involved in different stages of clear cell renal cell carcinoma

Hui‑Juan Li, Wen‑Xing Li, Shao‑Xing Dai, Yi‑Cheng Guo, Jun‑Juan Zheng, Jia‑Qian Liu, Qian Wang, Bi‑Wen Chen, Gong‑Hua Li, Jing‑Fei Huang
Pages: 2316-2322
Published online on: 08 December 2017

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Article Open Access

A novel synthetic ursolic acid derivative inhibits growth and induces apoptosis in breast cancer cell lines

Wei Li, Hongxiu Zhang, Mingxiu Nie, Wei Wang, Zongtao Liu, Ceshi Chen, Haijun Chen, Rong Liu, Zulqarnain Baloch, Ke Ma
Pages: 2323-2329
Published online on: 11 December 2017

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Article Open Access

Paclitaxel-induced hypothermia and hypoperfusion increase breast cancer metastasis and angiogenesis in mice

Nozomi Ami, Hideki Sato, Yoshihiro Hayakawa
Pages: 2330-2334
Published online on: 14 December 2017

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Article Open Access

Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA)

Ivan Bačić, Robert Karlo, Ana Šoštarić Zadro, Zvonko Zadro, Neven Skitarelić, Anko Antabak
Pages: 2335-2339
Published online on: 08 December 2017

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Article Open Access

Mechanism of anticancer action of novel berenil complex of platinum(II) combined with anti-MUC1 in MCF-7 breast cancer cells

Agnieszka Gornowicz, Anna Bielawska, Wojciech Szymanowski, Halina Gabryel‑Porowska, Robert Czarnomysy, Krzysztof Bielawski
Pages: 2340-2348
Published online on: 14 December 2017

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Article Open Access

MicroRNA-196a-5p is a potential prognostic marker of delayed lymph node metastasis in early-stage tongue squamous cell carcinoma

Tessho Maruyama, Kazuhide Nishihara, Masato Umikawa, Akira Arasaki, Toshiyuki Nakasone, Fumikazu Nimura, Akira Matayoshi, Kimiko Takei, Saori Nakachi, Ken‑Ichi Kariya, Naoki Yoshimi
Pages: 2349-2363
Published online on: 08 December 2017

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Article Open Access

Peroxiredoxin 1 expression in active ulcerative colitis mucosa identified by proteome analysis and involvement of thioredoxin based on immunohistochemistry

Kayo Horie, Tetuo Mikami, Tsutomu Yoshida, Yuichi Sato, Isao Okayasu
Pages: 2364-2372
Published online on: 08 December 2017

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Article Open Access

Effects of 16-bit CT imaging scanning conditions for metal implants on radiotherapy dose distribution

Liugang Gao, Hongfei Sun, Xinye Ni, Mingming Fang, Tao Lin
Pages: 2373-2379
Published online on: 11 December 2017

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Article

Association between inflammation and cancer stem cell phenotype in breast cancer

Young Ju Jeong, Hoon Kyu Oh, Sung Hwan Park, Jin Gu Bong
Pages: 2380-2386
Published online on: 13 December 2017

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Article

Granulocyte-colony stimulating factor producing mucinous cystic neoplasm with an associated invasive carcinoma of the pancreas

Kazuhide Shimamatsu, Yoshiki Naito, Yutaro Mihara, Masamichi Nakayama, Masahiko Tanigawa, Yushi Abe, Ken Nakamura, Toshihiro Araki, Kenji Sakata, Kazunori Noguchi, Jun Akiba, Hirohisa Yano, Osamu Nakashima
Pages: 2387-2392
Published online on: 08 December 2017

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Article

Carnosic acid, an inducer of NAD(P)H quinone oxidoreductase 1, enhances the cytotoxicity of β‑lapachone in melanoma cell lines

Nobuyuki Arakawa, Ayaka Okubo, Shinji Yasuhira, Kazuhiro Takahashi, Hiroo Amano, Toshihide Akasaka, Tomoyuki Masuda, Masahiko Shibazaki, Chihaya Maesawa
Pages: 2393-2400
Published online on: 14 December 2017

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Article

Decreased expression of CADM1 and CADM4 are associated with advanced stage breast cancer

Motonobu Saito, Akiteru Goto, Noriko Abe, Katsuharu Saito, Daichi Maeda, Tohru Ohtake, Yoshinori Murakami, Seiichi Takenoshita
Pages: 2401-2406
Published online on: 06 December 2017

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Article

A retrospective study of 34 patients with unicentric and multicentric Castleman's disease: Experience from a single institution

Jin‑Peng Jiang, Xiao‑Fei Shen, Jun‑Feng Du, Wen‑Xian Guan
Pages: 2407-2412
Published online on: 14 December 2017

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Article

Melanocyte-specific gene 1 promotes melanoma progression by enhancing the expression of Bcl-2

Hui Zhao, Guosheng Wu, Ji Zhu, Mengyan Sun, Yuchong Wang, Yongjie Fan, Kai Wu, Hongda Bi, Haiying Dai, Chuan Lv, Chunyu Xue
Pages: 2413-2418
Published online on: 12 December 2017

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Article

Molecular screening and the clinical impacts of BCR‑ABL KD mutations in patients with imatinib‑resistant chronic myeloid leukemia

Betül Koçkan, Tayfur Toptaş, Işik Atagündüz, Ayşe Tülin Tuğlular, Ayşe Özer, Mustafa Akkiprik
Pages: 2419-2424
Published online on: 13 December 2017

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Article

A novel function of NUCB2 in promoting the development and invasion of renal cell carcinoma

Huan Xu, Wenzhi Li, Kai Qi, Juan Zhou, Meng Gu, Zhong Wang
Pages: 2425-2430
Published online on: 08 December 2017

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Article

Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer

Young Ju Jeong, Sung Hwan Park, Sung Hee Mun, Sang Gyu Kwak, Sun‑Jae Lee, Hoon Kyu Oh
Pages: 2431-2440
Published online on: 14 December 2017

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Article

Dynamics of CRISPR/Cas9-mediated genomic editing of the AXL locus in hepatocellular carcinoma cells

Irene Scharf, Lisa Bierbaumer, Heidemarie Huber, Philipp Wittmann, Christine Haider, Christine Pirker, Walter Berger, Wolfgang Mikulits
Pages: 2441-2450
Published online on: 13 December 2017

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Article

Experience-based surgical approach to pancreatic mucinous cystic neoplasms with ovarian-type stroma

Chang Moo Kang, Akira Matsushita, Ho Kyoung Hwang, Yoko Matsuda, Hyunki Kim, Yoshiharu Nakamura, Woo Jung Lee
Pages: 2451-2458
Published online on: 14 December 2017

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Article

Anticancer effects of 10-hydroxycamptothecin induce apoptosis of human osteosarcoma through activating caspase-3, p53 and cytochrome c pathways

Xiong Min, Han Heng, Hua‑Long Yu, Mao Dan, Chen Jie, Yun Zeng, He Ning, Zhi‑Gang Liu , Zhi‑Yong Wang, Wang Lin
Pages: 2459-2464
Published online on: 13 December 2017

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Retrospective observational cohort study on cosmetic outcome of using Ti‑Ni memory alloy wire for intradermal suture following mastectomy in patients with breast cancer

Gang Li, Sida Qin, Xin Sun, Jiansheng Wang, Yunfeng Zhang, Jia Zhang, Jing Zhang, Shou‑Ching Tang, Hong Ren
Pages: 2465-2470
Published online on: 13 December 2017

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Article

Targeting breast cancer cells with a CuInS2/ZnS quantum dot-labeled Ki-67 bioprobe

Guang Sun, Wanying Xing, Ren Xing, Liu Cong, Sun Tong, Siyao Yu
Pages: 2471-2476
Published online on: 14 December 2017

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Article

Effect and molecular mechanism of mTOR inhibitor rapamycin on temozolomide‑induced autophagic death of U251 glioma cells

Bing Li, Chun Zhou, Liang Yi, Lunshan Xu, Minhui Xu
Pages: 2477-2484
Published online on: 06 December 2017

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Electron microscopic analysis of different cell types in human pancreatic cancer spheres

Toshiyuki Ishiwata, Fumio Hasegawa, Masaki Michishita, Norihiko Sasaki, Naoshi Ishikawa, Kaiyo Takubo, Yoko Matsuda, Tomio Arai, Junko Aida
Pages: 2485-2490
Published online on: 08 December 2017

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Article

A rare e14a3 BCR/ABL fusion transcript in acute lymphoblastic leukemia patient treated with CAR-modified T-cell therapy

Haodong Cai, Li Yang, Kefeng Shen, Wei Zhang, Jie Xiong, Meilan Zhang, Xia Mao, Ying Wang, Min Xiao
Pages: 2491-2494
Published online on: 13 December 2017

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Lymph node retrieval after dissolution of surrounding adipose tissue for pathological examination of colorectal cancer

Hiromichi Maeda, Ken Okamoto, Koji Oba, Mai Shiga, Yuki Fujieda, Tsutomu Namikawa, Makoto Hiroi, Ichiro Murakami, Kazuhiro Hanazaki, Michiya Kobayashi
Pages: 2495-2500
Published online on: 14 December 2017

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Article

Expression of CXC-motif-chemokine 12 and the receptor C‑X‑C receptor 4 in glioma and theeffect on peritumoral brain edema

Wenlong Tang, Yupeng Chen, Xingfu Wang, Yao Chen, Jiandong Zhang, Zhixiong Lin
Pages: 2501-2507
Published online on: 08 December 2017

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Article

miR-339-5p inhibits metastasis of non-small cell lung cancer by regulating the epithelial-to-mesenchymal transition

Yun Li, Xuelin Zhang, Zhen Yang, Yanan Li, Baiyu Han, Liang An Chen
Pages: 2508-2514
Published online on: 13 December 2017

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Article

Celastrol suppresses the proliferation of lung adenocarcinoma cells by regulating microRNA-24 and microRNA-181b

Yun‑Fei Yan, Han‑Han Zhang, Qing Lv, Yue‑Mei Liu, You‑Jie Li, Bao‑Sheng Li, Ping‑Yu Wang, Wen‑Jing Shang, Zhen Yue, Shu‑Yang Xie
Pages: 2515-2521
Published online on: 12 December 2017

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Characterization of circulating tumor cells in newly diagnosed breast cancer

Lu Xu, Songlin Jia, Hengyu Li, Yue Yu, Guoping Liu, Yanmei Wu, Xishui Liu, Chaoqian Liu, Yue Zhou, Zhenzhen Zhang, Yuan Sheng
Pages: 2522-2528
Published online on: 06 December 2017

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Case Report

A unique bone marrow lymphoma patient presenting with an isolated mass: A case report

Yi‑Wen Xu, Ming‑Hui Duan
Pages: 2529-2533
Published online on: 06 December 2017

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The expression and underlying angiogenesis effect of DPC4 and VEGF on the progression of cervical carcinoma

Yanni A, Ying Li, Shuping Zhao
Pages: 2534-2540
Published online on: 11 December 2017

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Development and in vitro evaluation of mucoadhesive patches of methotrexate for targeted delivery in oral cancer

Bao‑Zhong Jin, Xiao‑Qi Dong, Xin Xu, Feng‑He Zhang
Pages: 2541-2549
Published online on: 13 December 2017

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Article

Tanshinone II is a potent candidate for treatment of lipopolysaccharide-induced acute lung injury in rat model

Ling Li, Yong‑Gang Zhang, Yu‑Fei Tan, Jing‑Jing Zhao, Hua‑Ru Zhang, Bing Zhao
Pages: 2550-2554
Published online on: 11 December 2017

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Therapeutic effect of targeted Fas-expressing adenoviruses method combining γδ T cells in a mouse model of human ovarian carcinoma

Dingyuan Zeng, Jiajing Lin, Hongying He, Guangping Tan, Ying Lan, Fuyan Jiang, Shuting Sheng
Pages: 2555-2561
Published online on: 13 December 2017

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Dihydroartemisinin treatment of multiple myeloma cells causes activation of c-Jun leading to cell apoptosis

Yong Wang, Xiaoyuan Xu, Xiaojian Wu, Weibin Chen, Fangmei Huang, Xiaomin Gui
Pages: 2562-2566
Published online on: 11 December 2017

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Validation of the novel susceptibility loci for prostate cancer in a Chinese population

Yishuo Wu, Haitao Chen, Ying Ji, Rong Na, Zengnan Mo, Dingwei Ye, Meilin Wang, Jun Qi, Xiaoling Lin, Qiang Ding, Jianfeng Xu, S. Lilly Zheng, Yinghao Sun, Wei Meng
Pages: 2567-2573
Published online on: 13 December 2017

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Article

Prediction of long‑term survival rates in patients undergoing curative resection for solitary hepatocellular carcinoma

Yi Cao, Zhelong Jiang, Shaohu Wang, Haoyang Zhang, Yi Jiang, Lizhi Lv
Pages: 2574-2582
Published online on: 13 December 2017

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Article

Neddylation inhibitor MLN4924 induces G2 cell cycle arrest, DNA damage and sensitizes esophageal squamous cell carcinoma cells to cisplatin

Shan Lin, Zhaoyang Shang, Shuo Li, Peng Gao, Yi Zhang, Shuaiheng Hou, Peng Qin, Ziming Dong, Tao Hu, Ping Chen
Pages: 2583-2589
Published online on: 14 December 2017

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Article

Activin A induces apoptosis of mouse myeloma cells via the mitochondrial pathway

Yuanyi Zhang, Yan Qi, Yang Zhao, Hongyan Sun, Jingyan Ge, Zhonghui Liu
Pages: 2590-2594
Published online on: 11 December 2017

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Article

LATS2 promoter hypermethylation and its effect on gene expression in human breast cancer

Saki Matsui, Naofumi Kagara, Chieko Mishima, Yasuto Naoi, Masafumi Shimoda, Atsushi Shimomura, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi
Pages: 2595-2603
Published online on: 06 December 2017

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Article

Augmentation of antibody-dependent cellular cytotoxicity with defucosylated monoclonal antibodies in patients with GI-tract cancer

Takahiro Nakajima, Hirokazu Okayama, Mai Ashizawa, Masaru Noda, Keita Aoto, Motonobu Saito, Tomoyuki Monma, Shinji Ohki, Masahiko Shibata, Seiichi Takenoshita, Koji Kono
Pages: 2604-2610
Published online on: 08 December 2017

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Article

3‑Oxoacid CoA transferase 1 as a therapeutic target gene for cisplatin-resistant ovarian cancer

San‑Duk Yang, So Hee Ahn, Jong‑Il Kim
Pages: 2611-2618
Published online on: 08 December 2017

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Article

Genipin inhibits the growth of human bladder cancer cells via inactivation of PI3K/Akt signaling

Zheng Li, Tian‑Biao Zhang, Dong‑Hui Jia, Wen‑Qi Sun, Chao‑Liang Wang, Ao‑Zheng Gu, Xiao‑Ming Yang
Pages: 2619-2624
Published online on: 11 December 2017

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Article

Analysis of expression profile data identifies key genes and pathways in hepatocellular carcinoma

Xuwei Jiang, Yuqing Hao
Pages: 2625-2630
Published online on: 06 December 2017

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Article

Antitumor effect of membrane-type Tim-3 on hepatocellular carcinoma Hepa1-6 cells of ICR mice

Ju Liu, Haiying Sun, Dan Shen, Mingmin Wang, Zirong Wen
Pages: 2631-2634
Published online on: 14 December 2017

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Article

Capture of mesothelioma cells with ‘universal’ CTC-chip

Kazue Yoneda, Yasuhiro Chikaishi, Taiji Kuwata, Takashi Ohnaga, Fumihiro Tanaka
Pages: 2635-2640
Published online on: 14 December 2017

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Article

Association between clinicopathological factors and postoperative radiotherapy in patients with completely resected pathological N2 non-small cell lung cancer

Yujin Xu, Jianqiang Li, Jin Wang, Xiao Hu, Honglian Ma, Pu Li, Xiao Zheng, Ming Chen
Pages: 2641-2650
Published online on: 13 December 2017

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Article

Acridone suppresses the proliferation of human breast cancer cells in vitro via ATP-binding cassette subfamily G member 2

Licheng Xu, Shuyan Li, Zhi Liang, Haixia Lin, Rongzhan Fu
Pages: 2651-2654
Published online on: 11 December 2017

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Article

The effects of hemocyanin on T cells cultured in vitro

Jiani Liu, Cong Chen, Chen Ling, Haoyun Hu, Jingsong Cao, Yongqiang Gao
Pages: 2655-2660
Published online on: 11 December 2017

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Article

Expression and potential mechanism of metabolism-related genes and CRLS1 in non-small cell lung cancer

Hai‑Ming Feng, Ye Zhao, Jian‑Ping Zhang, Jian‑Hua Zhang, Peng Jiang, Bin Li, Cheng Wang
Pages: 2661-2668
Published online on: 12 December 2017

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Article

Abiraterone acetate withdrawal syndrome: Speculations on the underlying mechanisms

Tomonori Kato, Akira Komiya, Joji Yuasa, Kanya Kaga, Mayuko Kaga, Satoko Kojima, Yukio Naya, Shigeo Isaka
Pages: 2669-2672
Published online on: 14 December 2017

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Article

Mechanism of the anti-angiogenic effect of Avemar on tumor cells

Nilüfer Gülmen Imir, Esra Aydemir, Ece Şimşek
Pages: 2673-2678
Published online on: 13 December 2017

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Article

Salvianolic acid B suppresses cell proliferation and induces apoptosis in osteosarcoma through p38-mediated reactive oxygen species generation

Zhaoyang Zeng, Hua Zhang, Xin Wang, Kai Liu, Tian Li, Shaobo Sun, Hailong Li
Pages: 2679-2685
Published online on: 13 December 2017

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Article

Prediction of decannulation, oral intake recovery, overall survival and lung metastasis following oral malignant tumor resection and reconstruction

Hidenori Suzuki, Ikuo Hyodo, Yasuhisa Hasegawa
Pages: 2686-2694
Published online on: 11 December 2017

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Article

MicroRNA-122-3p inhibits tumor cell proliferation and induces apoptosis by targeting Forkhead box O in A549 cells

Wen Wang, Jinsong Yang, Fenglei Yu, Wenjie Li, Li Wang, Haoyu Zou, Xia Long
Pages: 2695-2699
Published online on: 11 December 2017

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Article

Overexpression of centrosomal protein 55 regulates the proliferation of glioma cell and mediates proliferation promoted by EGFRvIII in glioblastoma U251 cells

Hongfan Zhu, Diangang Chen, Jinliang Tang, Changlin Huang, Shengqing Lv, Donglin Wang, Guanghui Li
Pages: 2700-2706
Published online on: 08 December 2017

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Correction Open Access

[Corrigendum] A proposed method for the relative quantification of levels of circulating microRNAs in the plasma of gastric cancer patients

Mayra‑Cecilia Suárez‑Arriaga, Javier Torres, Margarita Camorlinga‑Ponce, Alejandro Gómez‑Delgado, Patricia Piña‑Sánchez, Hilda‑Alicia Valdez‑Salazar, Rosa‑María Ribas‑Aparicio, Ezequiel M. Fuentes‑Pananá, Martha‑Eugenia Ruiz‑Tachiquín
Pages: 2707-2707
Published online on: 14 December 2017

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Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
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Review
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Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
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Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Review Open Access

Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Review Open Access

Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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Article Open Access

An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Article Open Access

Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Article Open Access

Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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July-2026 Volume 32 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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