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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2018 Volume 15 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Mitogen-activated protein kinase signaling pathway in oral cancer (Review)

Qian Peng, Zhiyuan Deng, Hao Pan, Liqun Gu, Ousheng Liu, Zhangui Tang
Pages: 1379-1388
Published online on: 24 November 2017

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Review

Patellar metastasis from primary tumor (Review)

Gang Li, Changxing Shan, Ran Sun, Song Liu, Song Chen, Mingzhi Song, Ming Lu
Pages: 1389-1396
Published online on: 23 November 2017

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Article Open Access

Pediatric sarcomas (Review) Retraction in /10.3892/ol.2018.7943

Junhua Cao, Qi An, Lei Wang
Pages: 1397-1402
Published online on: 21 November 2017

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Article Open Access

CXCL5 secreted from adipose tissue‑derived stem cells promotes cancer cell proliferation

Yuying Zhao, Xiaosan Zhang, Hong Zhao, Jingxuan Wang, Qingyuan Zhang
Pages: 1403-1410
Published online on: 05 December 2017

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Article Open Access

Effects of liver cirrhosis on portal vein embolization prior to right hepatectomy in patients with primary liver cancer

Jun‑Hui Sun, Yue‑Lin Zhang, Chun‑Hui Nie, Ju Li, Tan‑Yang Zhou, Guan‑Hui Zhou, Tong‑Yin Zhu, Li‑Ming Chen, Wei‑Lin Wang, Shu‑Sen Zheng
Pages: 1411-1416
Published online on: 05 December 2017

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Article Open Access

The role of cadherin-11 in microcystin-LR-induced migration and invasion in colorectal carcinoma cells

Qiangqiang Zhu, Zhen Wang, Lihua Zhou, Yan Ren, Ying Gong, Wei Qin, Lin Bai, Jun Hu, Ting Wang
Pages: 1417-1422
Published online on: 21 November 2017

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Article Open Access

Piperlongumine induces apoptosis and autophagy in leukemic cells through targeting the PI3K/Akt/mTOR and p38 signaling pathways

Hongfei Wang, Yongqiang Wang, Hongmei Gao, Bing Wang, Lin Dou, Yin Li
Pages: 1423-1428
Published online on: 29 November 2017

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Article Open Access

Prognostic value of SPARCL1 in patients with colorectal cancer

Wei Han, Fang Cao, Wei Ding, Xiao‑Jiao Gao, Fang Chen, Yong‑Wei Hu, Hou‑Zhong Ding
Pages: 1429-1434
Published online on: 05 December 2017

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Article Open Access

MicroRNA-26b suppresses autophagy in breast cancer cells by targeting DRAM1 mRNA, and is downregulated by irradiation Corrigendum in /10.3892/ol.2021.12460

Cuida Meng, Yang Liu, Yannan Shen, Shuchun Liu, Zhicheng Wang, Qingsheng Ye, Hongyang Liu, Xiaodong Liu, Lili Jia
Pages: 1435-1440
Published online on: 21 November 2017

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Article Open Access

The ribosome inhibiting protein riproximin shows antineoplastic activity in experimental pancreatic cancer liver metastasis

Ahmed Murtaja, Ergül Eyol, Jiang Xiaoqi, Martin R. Berger, Hassan Adwan
Pages: 1441-1448
Published online on: 05 December 2017

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Article Open Access

Increased expression of mitochondrial transcription factor A and nuclear respiratory factor‑1 predicts a poor clinical outcome of breast cancer

Wei Gao, Meihong Wu, Ning Wang, Yingyi Zhang, Jing Hua, Gusheng Tang, Yajie Wang
Pages: 1449-1458
Published online on: 24 November 2017

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Article Open Access

Altered capicua transcriptional repressor gene expression exhibits distinct prognostic value for isocitrate dehydrogenase-mutant oligodendroglial tumors

Fuxin Han, Jinsong Zhang, Shanbo Ma, Xiaoyan Chen, Weiping Liu, Xiaosheng He, Zhou Fei, Yangang Wang
Pages: 1459-1468
Published online on: 21 November 2017

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Article Open Access

Utility of bronchial lavage fluids for epithelial growth factor receptor mutation assay in lung cancer patients: Comparison between cell pellets, cell blocks and matching tissue specimens

Shiho Asaka, Akihiko Yoshizawa, Rie Nakata, Tatsuya Negishi, Hiroshi Yamamoto, Takayuki Shiina, Shohei Shigeto, Kazuyuki Matsuda, Yukihiro Kobayashi, Takayuki Honda
Pages: 1469-1474
Published online on: 21 November 2017

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Article Open Access

MicroRNA‑150 inhibitors enhance cell apoptosis of melanoma by targeting PDCD4

Jianji Wan, Jie Yang, Yueshen Huang, Liehua Deng
Pages: 1475-1482
Published online on: 20 November 2017

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Article Open Access

The link between FOXJ1 expression level in bladder carcinoma and tumor recurrence Retraction in /10.3892/ol.2018.8920

Bing Liang, Xinwei He, Donghao Shang, Ye Tian, Zongwen Liu
Pages: 1483-1486
Published online on: 29 November 2017

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Article Open Access

Autophagy activation promotes bevacizumab resistance in glioblastoma by suppressing Akt/mTOR signaling pathway

He Huang, Jian Song, Zheng Liu, Li Pan, Guozheng Xu
Pages: 1487-1494
Published online on: 20 November 2017

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Article Open Access

Sodium butyrate induces senescence and inhibits the invasiveness of glioblastoma cells

Hidemitsu Nakagawa, Satoru Sasagawa, Kazuyuki Itoh
Pages: 1495-1502
Published online on: 05 December 2017

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Article Open Access

Comprehensive characterization of cancer genes in hepatocellular carcinoma genomes

Zhihao Zhang, Liping Xu, Changyu Sun
Pages: 1503-1510
Published online on: 05 December 2017

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Article Open Access

ARK5 promotes invasion and migration in hepatocellular carcinoma cells by regulating epithelial-mesenchymal transition

Zhiyu Ye, Xudong Chen, Xiaogang Chen
Pages: 1511-1516
Published online on: 21 November 2017

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Article Open Access

Oxaliplatin and infliximab synergize to induce regression of colon cancer

Di Huang, Jun Xue, Shuguang Li, Dongdong Yang
Pages: 1517-1522
Published online on: 22 November 2017

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Article Open Access

All-trans retinoic acid inhibits the proliferation of SGC7901 cells by regulating caveolin-1 localization via the ERK/MAPK signaling pathway

Sumei Zhang, Rui Shi, Shaolong Chen, Xiang Wei, Qing Zhou, Yuan Wang
Pages: 1523-1528
Published online on: 29 November 2017

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Article Open Access

Co‑existence of benign gynecological tumors with endometriosis in a group of 1,000 women

Charoula Matalliotaki, Michail Matalliotakis, Panagiotis Ieromonachou, George N. Goulielmos, Maria I. Zervou, Aggelos Laliotis, Demetrios A. Spandidos, Aydin Arici, Ioannis Matalliotakis
Pages: 1529-1532
Published online on: 20 November 2017

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Article Open Access

The relationship between cervical precancerous lesion galectin-3 and p27 protein expression and clinical prognosis

Jianting Ma, Xingguang Zhang, Gang He, Chunlin Yang
Pages: 1533-1536
Published online on: 29 November 2017

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Article Open Access

BmK CT enhances the sensitivity of temozolomide-induced apoptosis of malignant glioma U251 cells in vitro through blocking the AKT signaling pathway

Jun Du, Ruijie Wang, Litian Yin, Yuejun Fu, Yuqing Cai, Zhiyun Zhang, Aihua Liang
Pages: 1537-1544
Published online on: 24 November 2017

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Article Open Access

Effects of flurbiprofen on serum level of interleukin-6, prostacyclin and corticosteroid A2 in patients with bone metastases of cancer

Yanwei Yin, Yusheng Yi, Junmin Yu, Xiuming Sun, Chuansheng Liu, Fenghe Xu
Pages: 1545-1548
Published online on: 23 November 2017

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Article Open Access

Family with sequence similarity 83, member B is a predictor of poor prognosis and a potential therapeutic target for lung adenocarcinoma expressing wild‑type epidermal growth factor receptor

Takumi Yamaura, Junji Ezaki, Naoyuki Okabe, Hironori Takagi, Yuki Ozaki, Takuya Inoue, Yuzuru Watanabe, Mitsuro Fukuhara, Satoshi Muto, Yuki Matsumura, Takeo Hasegawa, Mika Hoshino, Jun Osugi, Yutaka Shio, Satoshi Waguri, Hirosumi Tamura, Jun‑Ichi Imai, Emi Ito, Yuka Yanagisawa, Reiko Honma, Shinya Watanabe, Hiroyuki Suzuki
Pages: 1549-1558
Published online on: 05 December 2017

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Article Open Access

Modulation of G2/M cell cycle arrest and apoptosis by luteolin in human colon cancer cells and xenografts

Zhicheng Chen, Bo Zhang, Feng Gao, Renjie Shi
Pages: 1559-1565
Published online on: 23 November 2017

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Article Open Access

Bufadienolides induce p53-mediated apoptosis in esophageal squamous cell carcinoma cells in vitro and in vivo

Shaohuan Lin, Junhong Lv, Panli Peng, Changqing Cai, Jianming Deng, Haihong Deng, Xuejun Li, Xinyue Tang
Pages: 1566-1572
Published online on: 21 November 2017

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Article Open Access

Platelet-derived growth factor-D promotes colorectal cancer cell migration, invasion and proliferation by regulating Notch1 and matrix metalloproteinase-9

Bin Jiang, Jinhuang Chen, Wenzheng Yuan, Jintong Ji, Zhengyi Liu, Liang Wu, Qiang Tang, Xiaogang Shu
Pages: 1573-1579
Published online on: 05 December 2017

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Article Open Access

Intracellular IL‑4 and IFN‑γ expression in iNKT cells from patients with chronic lymphocytic leukemia

Agnieszka Bojarska‑Junak, Małgorzata Waldowska, Justyna Woś, Sylwia Chocholska, Iwona Hus, Waldemar Tomczak, Michał Dzik, Marek Hus, Jacek Roliński
Pages: 1580-1590
Published online on: 24 November 2017

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Article Open Access

Celastrus orbiculatus extracts induce cell cycle arrest and apoptosis in human esophageal squamous carcinoma ECA-109 cells in vitro via the PI3K/AKT/mTOR signaling pathway

Feng Jin, Guang Zhu, Dan Li, Tengyang Ni, Xiaojun Dai, Haibo Wang, Jun Feng, Yayun Qian, Lin Yang, Shiyu Guo, Tadashi Hisamitsu, Yanqing Liu
Pages: 1591-1599
Published online on: 21 November 2017

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Article Open Access

Promoter methylation of RB1, P15, P16, and MGMT and their impact on the clinical course of pilocytic astrocytomas

Christoph Sippl, Steffi Urbschat, Yoo Jin Kim, Sebastian Senger, Joachim Oertel, Ralf Ketter
Pages: 1600-1606
Published online on: 24 November 2017

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Article Open Access

High-fat diet‑induced adipokine and cytokine alterations promote the progression of prostate cancer in vivo and in vitro

Meng‑Bo Hu, Hua Xu, Wen‑Hui Zhu, Pei‑De Bai, Ji‑Meng Hu, Tian Yang, Hao‑Wen Jiang, Qiang Ding
Pages: 1607-1615
Published online on: 21 November 2017

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Article Open Access

Correlation between TAP detection and common digestive tract precancerous lesions

Changqing Sun, Fang Deng, Lingjun Meng, Guohua Chen
Pages: 1616-1620
Published online on: 28 November 2017

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Article Open Access

miR‑125b regulates the drug‑resistance of breast cancer cells to doxorubicin by targeting HAX‑1

Guinv Hu, Xiaokang Zhao, Jiang Wang, Liting Lv, Chaoqun Wang, Liang Feng, Liangqiong Shen, Weili Ren
Pages: 1621-1629
Published online on: 23 November 2017

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Article Open Access

Silencing of suppressor of cytokine signaling 1 enhances the immunological effect of mucin 1-calreticulin-primed 4T1 cell-treated dendritic cells in breast cancer treatment

Song Qin, Zhipeng Gao, Yu Liu, Changbai Liu, Jun Wang, Li Li Zou
Pages: 1630-1638
Published online on: 23 November 2017

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Article Open Access

Comparison of the expression of TGF‑β1, E‑cadherin, N‑cadherin, TP53, RB1CC1 and HIF‑1α in oral squamous cell carcinoma and lymph node metastases of humans and mice

Mengzhu Guo, Yun Mu, Dahai Yu, Jing Li, Fengqiang Chen, Baosheng Wei, Shichang Bi, Jia Yu, Feixin Liang
Pages: 1639-1645
Published online on: 21 November 2017

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Article Open Access

Effects of HPV16E6 transfection on the biological behavior of Eca109 and Eca9706 cells Corrigendum in /10.3892/ol.2021.12552

Xin‑Dan Kang, Yong Zheng, Wei‑Gang Chen, Min Cheng, Di Zhang
Pages: 1646-1654
Published online on: 22 November 2017

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Article Open Access

Bioinformatic analysis of gene expression profiles of pituitary gonadotroph adenomas

Ziming Hou, Jun Yang, Gang Wang, Changjiang Wang, Hongbing Zhang
Pages: 1655-1663
Published online on: 30 November 2017

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Article Open Access

Pre‑treatment neutrophil‑to‑lymphocyte ratio predicts survival in patients with laryngeal cancer

Jintao Du, Jifeng Liu, Xinyuan Zhang, Xiaoting Chen, Rong Yu, Deying Gu, Jian Zou, Yafeng Liu, Shixi Liu
Pages: 1664-1672
Published online on: 29 November 2017

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Article Open Access

MiR‑370 promotes apoptosis in colon cancer by directly targeting MDM4

Xiaogang Shen, Xiaofei Zuo, Wenjin Zhang, Yifeng Bai, Xianpeng Qin, Nengyi Hou
Pages: 1673-1679
Published online on: 05 December 2017

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Article Open Access

Identification of common key genes in breast, lung and prostate cancer and exploration of their heterogeneous expression

Richa K. Makhijani, Shital A. Raut, Hemant J. Purohit
Pages: 1680-1690
Published online on: 30 November 2017

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Article Open Access

Effect of matrine against breast cancer by downregulating the vascular endothelial growth factor via the Wnt/β‑catenin pathway

Xu Xiao, Man Ao, Fan Xu, Xiao Li, Jiuli Hu, Ying Wang, Daixiao Li, Xiaoqin Zhu, Chunlan Xin, Wenda Shi
Pages: 1691-1697
Published online on: 05 December 2017

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Article Open Access

Diagnostic evaluations of ultrasound and magnetic resonance imaging in mammary duct ectasia and breast cancer

Lei Song, Liang Li, Bin Liu, Dexin Yu, Fengguo Sun, Mingming Guo, Zhengmin Ruan, Feixue Zhang
Pages: 1698-1706
Published online on: 05 December 2017

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Article Open Access

High frequency and prognostic value of MYD88 L265P mutation in diffuse large B‑cell lymphoma with R‑CHOP treatment

Sisi Yu, Huaichao Luo, Meiling Pan, Luis Angel Palomino, Xiaoyu Song, Ping Wu, Jian‑Ming Huang, Zhihui Zhang
Pages: 1707-1715
Published online on: 22 November 2017

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Article Open Access

Logistic regression analysis of risk factors for postoperative recurrence of spinal tumors and analysis of prognostic factors

Shanyong Zhang, Lili Yang, Chuangang Peng, Minfei Wu
Pages: 1716-1722
Published online on: 04 December 2017

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Article Open Access

miR-93 enhances cell proliferation by directly targeting CDKN1A in nasopharyngeal carcinoma

Yingyao Zhang, Zhina Xu
Pages: 1723-1727
Published online on: 24 November 2017

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Article Open Access

Cytotoxic effect of Efavirenz in BxPC‑3 pancreatic cancer cells is based on oxidative stress and is synergistic with ionizing radiation

Markus Hecht, Thomas Harrer, Verena Körber, Eric O. Sarpong, Fabian Moser, Nora Fiebig, Manuela Schwegler, Michael Stürzl, Rainer Fietkau, Luitpold V. Distel
Pages: 1728-1736
Published online on: 05 December 2017

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Article Open Access

A hederagenin saponin isolated from Clematis ganpiniana induces apoptosis in breast cancer cells via the mitochondrial pathway

Lin Cheng, Liang Shi, Jing Wu, Xujie Zhou, Xiaoxia Li, Xi Sun, Lei Zhu, Tian‑Song Xia, Qiang Ding
Pages: 1737-1743
Published online on: 27 November 2017

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Article Open Access

Characterization of the T‑cell receptor repertoire by deep T cell receptor sequencing in tissues from patients with prostate cancer

Song Liu, Weibing Pan, Zhiqiang Cheng, Guoping Sun, Peng Zhu, Franky Chan, Yunlong Hu, Xinzhou Zhang, Yong Dai
Pages: 1744-1752
Published online on: 23 November 2017

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Article Open Access

Expression of miR-590 in lung cancer and its correlation with prognosis

Zhifeng Ma, Yaoqin Wang, Binjun He, Jian Cui, Chu Zhang, Haiyong Wang, Weizhong Feng, Bin Wang, Desheng Wei, Yuanlin Wu, Yong Zeng, Guangmao Yu
Pages: 1753-1757
Published online on: 28 November 2017

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Article

Mechanisms for DNA‑damaging agent‑induced inactivation of ErbB2 and ErbB3 via the ERK and p38 signaling pathways

Chul Min Park, Yuki Kawasaki, Alaa Refaat, Hiroaki Sakurai
Pages: 1758-1762
Published online on: 05 December 2017

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Article

Regulator of G‑protein signaling 5 enhances portal vein invasion in hepatocellular carcinoma

Yumi Umeno, Sachiko Ogasawara, Jun Akiba, Satoshi Hattori, Hironori Kusano, Osamu Nakashima, Hironori Koga, Takuji Torimura, Ryoji Yamakawa, Hirohisa Yano
Pages: 1763-1770
Published online on: 23 November 2017

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Article

Mechanisms by which CXCR4/CXCL12 cause metastatic behavior in pancreatic cancer

Jianbo Zhang, Chengxin Liu, Xinkai Mo, Huan Shi, Sheng Li
Pages: 1771-1776
Published online on: 05 December 2017

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Article

Antitumor effects of matrine on cancer stem like cells isolated from the human liver cancer SMMC‑7721 cell line

Yong Wang, Yahui Liu, Jianshuai Jiang, Hanbin Cui
Pages: 1777-1782
Published online on: 05 December 2017

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Article

Soluble HER3 predicts survival in bladder cancer patients

Ashfaque A. Memon, Stephen C. Gilliver, Michael Borre, Jan Sundquist, Kristina Sundquist, Ebba Nexo, Boe S. Sorensen
Pages: 1783-1788
Published online on: 22 November 2017

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Article

Piperlongumine inhibits cancer stem cell properties and regulates multiple malignant phenotypes in oral cancer

Yin‑Ju Chen, Chia‑Chun Kuo, Lai‑Lei Ting, Long‑Sheng Lu, Ya‑Ching Lu, Ann‑Joy Cheng, Yun‑Tien Lin, Chien‑Ho Chen, Jo‑Ting Tsai, Jeng‑Fong Chiou
Pages: 1789-1798
Published online on: 24 November 2017

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Article

A retrospective, single‑center cohort study on 65 patients with primary retroperitoneal liposarcoma

Yi‑Xi Wu, Jun‑Yan Liu, Jia‑Jia Liu, Peng Yan, Bo Tang, You‑Hong Cui, Yong‑Liang Zhao, Yan Shi, Ying‑Xue Hao, Pei‑Wu Yu, Feng Qian
Pages: 1799-1810
Published online on: 05 December 2017

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Article

Metformin synergizes with rapamycin to inhibit the growth of pancreatic cancer in vitro and in vivo

Jia‑Wei Zhang, Fan Zhao, Qing Sun
Pages: 1811-1816
Published online on: 20 November 2017

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Article

Progesterone impairs Herceptin effect on breast cancer cells

Kamila Kitowska, Agnieszka Kowalska, Magdalena Mieszkowska, Dominika Piasecka, Andrzej C. Skladanowski, Hanna M. Romanska, Rafal Sadej
Pages: 1817-1822
Published online on: 27 November 2017

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Article

A multidisciplinary group for prostate cancer management: A single institution experience

Antonella Colasante, Antonietta Augurio, Raffaella Basilico, Antonio Raffaele Cotroneo, Maria B. Di Sciascio, Giuseppe Gaspari, Domenico Genovesi, Jamara Giampietro, Romina Iantorno, Antonio Marchetti, Clara Natoli, Antonello Nuzzo, Floriana Ottaviani, Paolo Pompa, Pietro Castellan, Raffaele Tenaglia, Annamaria Vinciguerra
Pages: 1823-1828
Published online on: 30 November 2017

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Article

Microarray pathway analysis indicated that mitogen-activated protein kinase/extracellular signal-regulated kinase and insulin growth factor 1 signaling pathways were inhibited by small interfering RNA against AT‑rich interactive domain 1A in endometrial cancer

Ye Yang, Wei Bao, Zhengyu Sang, Yongbing Yang, Meng Lu, Xiaowei Xi
Pages: 1829-1838
Published online on: 24 November 2017

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Article

Clinical significance of BRAFV600E mutation in circulating tumor DNA in Chinese patients with melanoma

Huan Tang, Yan Kong, Lu Si, Chuanliang Cui, Xinan Sheng, Zhihong Chi, Jie Dai, Sifan Yu, Meng Ma, Xiaowen Wu, Jiayi Yu, Tianxiao Xu, Huan Yu, Junya Yan, Jun Guo
Pages: 1839-1844
Published online on: 05 December 2017

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Article

18F-fluorodeoxyglucose positron emission computed tomography for monitoring tumor response in esophageal carcinoma treated with concurrent chemoradiotherapy

Peiliang Zhang, Zengyun Li, Dongqing Wang, Fuling Ma, Ran Zhang, Wanhua Liang, Mingping Sun, Zheng Fu, Xiaorong Sun
Pages: 1845-1852
Published online on: 05 December 2017

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Article

Prognostic relevance of FGFR2 expression in stage II/III gastric cancer with curative resection and S‑1 chemotherapy

Kei Hosoda, Keishi Yamashita, Hideki Ushiku, Akira Ema, Hiromitsu Moriya, Hiroaki Mieno, Marie Washio, Masahiko Watanabe
Pages: 1853-1860
Published online on: 05 December 2017

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Article

lncRNA FAM83H‑AS1 is associated with the prognosis of colorectal carcinoma and promotes cell proliferation by targeting the Notch signaling pathway

Song Lu, Wei Dong, Pei Zhao, Zhenjun Liu
Pages: 1861-1868
Published online on: 05 December 2017

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Article

Licochalcone A inhibits PI3K/Akt/mTOR signaling pathway activation and promotes autophagy in breast cancer cells

Lei Xue, Wei‑Jie Zhang, Qing‑Xia Fan, Liu‑Xing Wang
Pages: 1869-1873
Published online on: 21 November 2017

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Article

Endostatin reverses immunosuppression of the tumor microenvironment in lung carcinoma

Xiaolin Liu, Weiwei Nie, Qi Xie, Guoling Chen, Xingyu Li, Yanrui Jia, Beibei Yin, Xun Qu, Yan Li, Jing Liang
Pages: 1874-1880
Published online on: 21 November 2017

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Article

Low-dose paclitaxel downregulates MYC proto-oncogene bHLH transcription factor expression in colorectal carcinoma cells

Wenjing Li, Wanyun Zhu, Chaoxiang Lv, Hao Qu, Kaixiang Xu, Honghui Li, Haifeng Li, Yiming Du, Guangming Liu, Yunyue Wang, Hong‑Jiang Wei, Hong‑Ye Zhao
Pages: 1881-1887
Published online on: 05 December 2017

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Article

Association between expression of nuclear receptor co‑activator 5 protein and prognosis in postoperative patients with osteosarcoma

Ya Wu, Jian Wu, Qi‑Rong Dong, Nai‑Zhou Guo
Pages: 1888-1892
Published online on: 05 December 2017

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Article

PI3K/AKT/Afadin signaling pathway contributes to pathological vascularization in glioblastomas

Xuan Zhai, Yingliang Li, Ping Liang, Lusheng Li, Yudong Zhou, Weidan Zhang, Difei Wang, Guanghui Wei
Pages: 1893-1899
Published online on: 21 November 2017

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Article

AXL is a marker for epithelial‑mesenchymal transition in esophageal squamous cell carcinoma

Guoan Zhang, Xia Kong, Meng Wang, Hongli Zhao, Sha Han, Ronghang Hu, Jian Huang, Wen Cui
Pages: 1900-1906
Published online on: 20 November 2017

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Article

Combined small cell carcinoma with giant cell carcinoma component of the lung: A case successfully diagnosed by computed tomography‑guided fine‑needle aspiration cytology

Yusuke Ebisu, Mitsuaki Ishida, Tomohito Saito, Tomohiro Murakawa, Yoshiko Uemura, Koji Tsuta
Pages: 1907-1911
Published online on: 20 November 2017

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Article

Severe acute toxicity following gemcitabine administration: A report of four cases with cytidine deaminase polymorphisms evaluation

Beata Hryciuk, Bartosz Szymanowski, Anna Romanowska, Ewa Salt, Bartosz Wasąg, Bartłomiej Grala, Jacek Jassem, Renata Duchnowska
Pages: 1912-1916
Published online on: 22 November 2017

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Article

MEG3 inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells

Yao Shi, Chen Lv, Li Shi, Guanjun Tu
Pages: 1917-1923
Published online on: 21 November 2017

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Article

lncRNA SNHG5 is associated with poor prognosis of bladder cancer and promotes bladder cancer cell proliferation through targeting p27

Zhipeng Ma, Senyao Xue, Bi Zeng, Daoxian Qiu
Pages: 1924-1930
Published online on: 05 December 2017

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Article

Effects of harmaline on cell growth of human liver cancer through the p53/p21 and Fas/FasL signaling pathways

Bin Xu, Minpeng Li, Yuan Yu, Jun He, Siqin Hu, Meng Pan, Shifeng Lu, Ke Liao, Zhuang Pan, Yanxun Zhou, Jiye Zhu
Pages: 1931-1936
Published online on: 28 November 2017

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Article

Bone marrow stromal cells enhance the survival of chronic lymphocytic leukemia cells by regulating HES‑1 gene expression and H3K27me3 demethylation

Zhenshu Xu, Donglian Xiong, Jushun Zhang, Jingyan Zhang, Xiuli Chen, Zhizhe Chen, Rong Zhan
Pages: 1937-1942
Published online on: 21 November 2017

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Article

Down‑expression of poly(ADP‑ribose) polymerase in p53‑regulated pancreatic cancer cells

Zhenyu Hou, Yunfeng Cui, Huizhi Xing, Xiaoyan Mu
Pages: 1943-1948
Published online on: 29 November 2017

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Article

Dihydroartemisinin increases apoptosis of colon cancer cells through targeting Janus kinase 2/signal transducer and activator of transcription 3 signaling

Dongsheng Wang, Bei Zhong, Yu Li, Xiaodong Liu
Pages: 1949-1954
Published online on: 29 November 2017

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Article

Intra‑arterial interventional therapy for inoperable local advanced breast cancer: A retrospective study

Jing Ma, Jin Song, Hai Chen, Cibo Fan, Jiaqi Xie, Xiaodong Qi
Pages: 1955-1962
Published online on: 30 November 2017

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Article

Folate deficiency and aberrant DNA methylation and expression of FHIT gene were associated with cervical pathogenesis

Qiaoling Li, Ling Ding, Nan Jing, Chunliang Liu, Zuokai Yang, Fang Chen, Lifang Hou, Jintao Wang
Pages: 1963-1972
Published online on: 22 November 2017

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Article

Cytotoxic action of methylquercetins in human lung adenocarcinoma cells

Katrin Sak, Helen Lust, Marju Kase, Jana Jaal
Pages: 1973-1978
Published online on: 21 November 2017

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Article

ABT‑737 and pictilisib synergistically enhance pitavastatin‑induced apoptosis in ovarian cancer cells

Elizabeth De Wolf, Christopher De Wolf, Alan Richardson
Pages: 1979-1984
Published online on: 05 December 2017

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Article

Synergistic inhibition of colon cancer cell growth by a combination of atorvastatin and phloretin

Mo Zhou, Jinkai Zheng, Jinfeng Bi, Xinye Wu, Jian Lyu, Kun Gao
Pages: 1985-1992
Published online on: 23 November 2017

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Article

Preclinical study on hypoxic radiosensitizing effects of glycididazole in comparison with those of doranidazole in vitro and in vivo

Hironobu Yasui, Nobuo Kubota, Junko Nishizumi, Yuri Sakai, Tohru Yamamori, Osamu Inanami
Pages: 1993-1998
Published online on: 23 November 2017

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Article

Oridonin increases anticancer effects of lentinan in HepG2 human hepatoblastoma cells

Zhiqiang Sun, Qinghe Han, Liwei Duan, Qinghai Yuan, Hui Wang
Pages: 1999-2005
Published online on: 24 November 2017

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Article

Reversible growth arrest of 3D tumor spheroids stored in oxygen absorber-induced anoxia

Aurélie Gomes, Matthieu Defaux, Riwanon Michel Lemee, Valérie Lobjois, Bernard Ducommun
Pages: 2006-2009
Published online on: 21 November 2017

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Article

Role of prolactin/adenoma maximum diameter and prolactin/adenoma volume in the differential diagnosis of prolactinomas and other types of pituitary adenomas

Yinxing Huang, Chenyu Ding, Fangfang Zhang, Deyong Xiao, Lin Zhao, Shousen Wang
Pages: 2010-2016
Published online on: 21 November 2017

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Article

Characterization of cluster of differentiation 47 expression and its potential as a therapeutic target in esophageal squamous cell cancer

Chun‑Lin Zhao, Shuang Yu, Shu‑Hui Wang, Shi‑Gang Li, Zhi‑Ju Wang, Sheng‑Na Han
Pages: 2017-2023
Published online on: 20 November 2017

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Article

Chloroquine exerts antitumor effects on NB4 acute promyelocytic leukemia cells and functions synergistically with arsenic trioxide

Shousheng Liu, Xiuyu Cai, Liangping Xia, Chang Jiang, Ping Chen, Xiaopai Wang, Bei Zhang, Hong Yun Zhao
Pages: 2024-2030
Published online on: 24 November 2017

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Review

Surface markers of liver cancer stem cells and innovative targeted-therapy strategies for HCC (Review)

Lige Qiu, Hailiang Li, Sirui Fu, Xiaofang Chen, Ligong Lu
Pages: 2039-2048
Published online on: 08 December 2017

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Review

Epigenetic actions of environmental factors and promising drugs for cancer therapy (Review)

Zhong‑Tian Bai, Bing Bai, Jun Zhu, Cui‑Xia Di, Xun Li, Wen‑Ce Zhou
Pages: 2049-2056
Published online on: 13 December 2017

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Article Open Access

Transcriptome profiling of cancer tissues in Chinese patients with gastric cancer by high-throughput sequencing

Peiying Tian, Chunli Liang
Pages: 2057-2064
Published online on: 08 December 2017

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Article Open Access

Upregulated solute carrier family 37 member 1 in colorectal cancer is associated with poor patient outcome and metastasis

Daiki Kikuchi, Motonobu Saito, Katsuharu Saito, Yohei Watanabe, Yoshiko Matsumoto, Yasuyuki Kanke, Hisashi Onozawa, Suguru Hayase, Wataru Sakamoto, Teruhide Ishigame, Tomoyuki Momma, Shinji Ohki, Seiichi Takenoshita
Pages: 2065-2072
Published online on: 08 December 2017

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Article Open Access

High expression of RACK1 is associated with poor prognosis in patients with pancreatic ductal adenocarcinoma

Hailin Han, Dongmei Wang, Maowu Yang, Shenhao Wang
Pages: 2073-2078
Published online on: 06 December 2017

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Case Report Open Access

Extranodal presentation of Hodgkin's lymphoma of the sternum: A case report and review of the literature

Yan Li, You Qin, Liduan Zheng, Hong Liu
Pages: 2079-2084
Published online on: 07 December 2017

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Article Open Access

Fyn knockdown inhibits migration and invasion in cholangiocarcinoma through the activated AMPK/mTOR signaling pathway

Shao‑Cheng Lyu, Dong‑Dong Han, Xian‑Liang Li, Jun Ma, Qiao Wu, Hong‑Meng Dong, Chun Bai, Qiang He
Pages: 2085-2090
Published online on: 07 December 2017

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Article Open Access

Application values of 3.0T magnetic resonance diffusion weighted imaging for distinguishing liver malignant tumors and benign lesions

Ruibin Li, Guangyao Wu, Rui Wang
Pages: 2091-2096
Published online on: 08 December 2017

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Article Open Access

Novel betulin derivative induces anti-proliferative activity by G2/M phase cell cycle arrest and apoptosis in Huh7 cells

Zhen‑Jian Zhuo, Min‑Jie Xiao, Hui‑Ran Lin, Jing Luo, Tao Wang
Pages: 2097-2104
Published online on: 08 December 2017

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Article Open Access

Notch signaling via regulation of RB and p‑AKT but not PIK3CG contributes to MIA PaCa‑2 cell growth and migration to affect pancreatic carcinogenesis

Shubing Zhang, Jingjiang Liu, Keli Xu, Zhijian Li
Pages: 2105-2110
Published online on: 08 December 2017

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p68 prompts the epithelial‑mesenchymal transition in cervical cancer cells by transcriptionally activating the TGF‑β1 signaling pathway Retraction in /10.3892/ol.2024.14708

Ming‑Yi Li, Jin‑Quan Liu, Dong‑Ping Chen, Zhou‑Yu Li, Bin Qi, Wen‑Jing Yin, Lu He
Pages: 2111-2116
Published online on: 08 December 2017

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Article Open Access

Long non‑coding RNA MALAT‑1 contributes to maintenance of stem cell‑like phenotypes in breast cancer cells Retraction in /10.3892/ol.2024.14292

Linghuan Zeng, Ying Cen, Junjie Chen
Pages: 2117-2122
Published online on: 08 December 2017

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Article

Immunohistochemical CD73 expression status in gastrointestinal neuroendocrine neoplasms: A retrospective study of 136 patients

Kohei Ono, Eisuke Shiozawa, Nobuyuki Ohike, Tomonori Fujii, Hideki Shibata, Tetsuya Kitajima, Koichiro Fujimasa, Naoko Okamoto, Yukiko Kawaguchi, Tasuku Nagumo, Sakiko Tazawa, Mayumi Homma, Toshiko Yamochi‑Onizuka, Tomoko Norose, Hitoshi Yoshida, Masahiko Murakami, Gensyu Tate, Masafumi Takimoto
Pages: 2123-2130
Published online on: 08 December 2017

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Article Open Access

Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer

Xueping Quan, Hongjun Gao, Zhikuan Wang, Jie Li, Wentao Zhao, Wei Liang, Qiang Yu, Dongliang Guo, Zhanping Hao, Jingxin Liu
Pages: 2131-2138
Published online on: 14 December 2017

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Article Open Access

The association between differentially expressed micro RNAs in breast cancer cell lines and the micro RNA‑205 gene polymorphism in breast cancer tissue

Jingcheng Zhang, Bin Wei, Huixian Hu, Fanrong Liu, Yan Tu, Fang He
Pages: 2139-2146
Published online on: 08 December 2017

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Article Open Access

Knockdown of Arf6 increases drug sensitivity and inhibits proliferation, migration and invasion in gastric cancer SGC‑7901 cells

Junlan Qiu, Liang Tao, Qiang Wei, Pingyang Zhang
Pages: 2147-2152
Published online on: 08 December 2017

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Article Open Access

Role of serine/threonine kinase 33 methylation in colorectal cancer and its clinical significance

Ming‑Di Yin, Si‑Ping Ma, Fang Liu, Yu‑Ze Chen
Pages: 2153-2160
Published online on: 14 December 2017

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Characterization and prognostic significance of mortalin, Bcl‑2 and Bax in intrahepatic cholangiocarcinoma

Qiang Kang, Hao Zou, Xuan Yang, Jia‑Bin Cai, Li‑Xin Liu, Nan Xie, Lian‑Min Wang, Yue‑Hua Li, Xiao‑Wen Zhang
Pages: 2161-2168
Published online on: 08 December 2017

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Article Open Access

Correlation between circulating tumor cells and D-D and platelet in patients with pulmonary malignancies

Lijun Yang, Hai Dong, Zixuan Li, Yongyue Pan, La Qu, Zhiwen Tan
Pages: 2169-2172
Published online on: 12 December 2017

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Association of abnormal glucose metabolism and insulin resistance in patients with atypical and typical endometrial cancer

Yongjing Lai, Chuanying Sun
Pages: 2173-2178
Published online on: 12 December 2017

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Article Open Access

Long-term outcomes of patients with soft tissue sarcoma of the chest wall: Analysis of the prognostic significance of microscopic margins

Kamran Harati, Jonas Kolbenschlag, Jens Bohm, Hiltrud Niggemann, Hamid Joneidi‑Jafari, Ingo Stricker, Marcus Lehnhardt, Adrien Daigeler
Pages: 2179-2187
Published online on: 14 December 2017

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Enhanced expression of KIF4A in colorectal cancer is associated with lymph node metastasis

Yoshiko Matsumoto, Motonobu Saito, Katsuharu Saito, Yasuyuki Kanke, Yohei Watanabe, Hisashi Onozawa, Suguru Hayase, Wataru Sakamoto, Teruhide Ishigame, Tomoyuki Momma, Kensuke Kumamoto, Shinji Ohki, Seiichi Takenoshita
Pages: 2188-2194
Published online on: 08 December 2017

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BRAF V600E mutation is a predictive indicator of upfront chemotherapy for stage IV colorectal cancer

Tatsuya Morikawa, Ryo Inada, Takeshi Nagasaka, Yoshiko Mori, Hiroyuki Kishimoto, Takashi Kawai, Yuzo Umeda, Hideyuki Mishima, Ajay Goel, Toshiyoshi Fujiwara
Pages: 2195-2201
Published online on: 08 December 2017

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PAK5 overexpression is associated with lung metastasis in osteosarcoma

Kun Han, Yan Zhou, Kuo‑Fu Tseng, Haiyan Hu, Kunpeng Li, Yaling Wang, Zhihua Gan, Shuchen Lin, Yongning Sun, Daliu Min
Pages: 2202-2210
Published online on: 07 December 2017

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Article Open Access

Upregulation of pyruvate kinase M2 expression by fatty acid synthase contributes to gemcitabine resistance in pancreatic cancer

Shenghua Tian, Pingping Li, Shi Sheng, Xin Jin
Pages: 2211-2217
Published online on: 13 December 2017

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Oxibendazole inhibits prostate cancer cell growth

Qiaoli Chen, Yuhua Li, Xiaoyu Zhou, Runsheng Li
Pages: 2218-2226
Published online on: 11 December 2017

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Vernodalol mediates antitumor effects in acute promyelocytic leukemia cells

Wenjun Wu, Xiaoyan Han, Cai Wu, Guoqing Wei, Gaofeng Zheng, Yi Li, Yang Yang, Li Yang, Donghua He, Yi Zhao, Zhen Cai
Pages: 2227-2235
Published online on: 07 December 2017

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Article Open Access

Increased expression of hepcidin and associated upregulation of JAK/STAT3 signaling in human gastric cancer

Erdong Zuo, Ye Lu, Min Yan, Xiangtao Pan, Xu Cheng
Pages: 2236-2244
Published online on: 08 December 2017

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Neuropilin-1 promotes primary liver cancer progression by potentiating the activity of hepatic stellate cells

Zhi‑Chao Xu, Hao‑Xin Shen, Chen Chen, Li Ma, Wen‑Zhi Li, Lin Wang, Zhi‑Min Geng
Pages: 2245-2251
Published online on: 07 December 2017

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Article Open Access

Quercetin reverses the doxorubicin resistance of prostate cancer cells by downregulating the expression of c‑met

Yan Shu, Bo Xie, Zhen Liang, Jing Chen
Pages: 2252-2258
Published online on: 08 December 2017

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Article Open Access

PD‑L1 expression is associated with p16INK4A expression in non‑oropharyngeal head and neck squamous cell carcinoma

San‑Chi Chen, Peter Mu‑Hsin Chang, Hsiao‑Jung Wang, Shyh‑Kuan Tai, Pen‑Yuan Chu, Muh‑Hwa Yang
Pages: 2259-2265
Published online on: 08 December 2017

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Article Open Access

The hepatoprotective role of reduced glutathione and its underlying mechanism in oxaliplatin-induced acute liver injury

Youzhi Lin, Yongqiang Li, Xiaohua Hu, Zhihui Liu, Jun Chen, Yulei Lu, Juan Liu, Sina Liao, Yumei Zhang, Rong Liang, Yan Lin, Qian Li, Caoyong Liang, Chunling Yuan, Xiaoli Liao
Pages: 2266-2272
Published online on: 12 December 2017

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Article Open Access

Effects of disodium cantharidinate on dendritic cells of patients with bladder carcinoma

Guang-Hui Zang, Rui Li, Rong-Sheng Zhou, Lin Hao, Hou-Guang He, Wen-Da Zhang, Yang Dong, Cong-Hui Han
Pages: 2273-2277
Published online on: 12 December 2017

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Article Open Access

Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions

Francisco Israel Torres‑Rojas, Luz del Carmen Alarcón‑Romero, Marco Antonio Leyva‑Vázquez, Julio Ortiz‑Ortiz, Miguel Ángel Mendoza‑Catalán, Daniel Hernández‑Sotelo, Oscar Del Moral‑Hernández, Hugo Alberto Rodríguez‑Ruiz, Dinorah Leyva‑Illades, Eugenia Flores-Alfaro, Berenice Illades‑Aguiar
Pages: 2278-2286
Published online on: 13 December 2017

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Article Open Access

β‑catenin, leucine-rich repeat-containing G protein-coupled receptor 5 and GATA-binding factor 6 are associated with the normal mucosa‑adenoma‑adenocarcinoma sequence of colorectal tumorigenesis

Bin Yang, Liang Mao, Yan Li, Qia Li, Xioli Li, Yunjing Zhang, Zhenhua Zhai
Pages: 2287-2295
Published online on: 08 December 2017

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Article Open Access

Prognostic value and functional role of ROCK2 in pediatric Ewing sarcoma

Gabriela Maciel Vieira, Gabriela Molinari Roberto, Régia Caroline Lira, Edgard Eduard Engel, Luiz Gonzaga Tone, María Sol Brassesco
Pages: 2296-2304
Published online on: 08 December 2017

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Article Open Access

Genetic characterization and in vitro activity of antimicrobial combinations of multidrug-resistant Acinetobacter baumannii from a general hospital in China

Fang Chen, Ling Wang, Min Wang, Yixin Xie, Xiaomeng Xia, Xianping Li, Yanhua Liu, Wei Cao, Tingting Zhang, Pengling Li, Min Yang
Pages: 2305-2315
Published online on: 13 December 2017

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Article Open Access

Identification of metabolism-associated genes and pathways involved in different stages of clear cell renal cell carcinoma

Hui‑Juan Li, Wen‑Xing Li, Shao‑Xing Dai, Yi‑Cheng Guo, Jun‑Juan Zheng, Jia‑Qian Liu, Qian Wang, Bi‑Wen Chen, Gong‑Hua Li, Jing‑Fei Huang
Pages: 2316-2322
Published online on: 08 December 2017

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Article Open Access

A novel synthetic ursolic acid derivative inhibits growth and induces apoptosis in breast cancer cell lines

Wei Li, Hongxiu Zhang, Mingxiu Nie, Wei Wang, Zongtao Liu, Ceshi Chen, Haijun Chen, Rong Liu, Zulqarnain Baloch, Ke Ma
Pages: 2323-2329
Published online on: 11 December 2017

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Article Open Access

Paclitaxel-induced hypothermia and hypoperfusion increase breast cancer metastasis and angiogenesis in mice

Nozomi Ami, Hideki Sato, Yoshihiro Hayakawa
Pages: 2330-2334
Published online on: 14 December 2017

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Article Open Access

Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA)

Ivan Bačić, Robert Karlo, Ana Šoštarić Zadro, Zvonko Zadro, Neven Skitarelić, Anko Antabak
Pages: 2335-2339
Published online on: 08 December 2017

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Article Open Access

Mechanism of anticancer action of novel berenil complex of platinum(II) combined with anti-MUC1 in MCF-7 breast cancer cells

Agnieszka Gornowicz, Anna Bielawska, Wojciech Szymanowski, Halina Gabryel‑Porowska, Robert Czarnomysy, Krzysztof Bielawski
Pages: 2340-2348
Published online on: 14 December 2017

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Article Open Access

MicroRNA-196a-5p is a potential prognostic marker of delayed lymph node metastasis in early-stage tongue squamous cell carcinoma

Tessho Maruyama, Kazuhide Nishihara, Masato Umikawa, Akira Arasaki, Toshiyuki Nakasone, Fumikazu Nimura, Akira Matayoshi, Kimiko Takei, Saori Nakachi, Ken‑Ichi Kariya, Naoki Yoshimi
Pages: 2349-2363
Published online on: 08 December 2017

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Article Open Access

Peroxiredoxin 1 expression in active ulcerative colitis mucosa identified by proteome analysis and involvement of thioredoxin based on immunohistochemistry

Kayo Horie, Tetuo Mikami, Tsutomu Yoshida, Yuichi Sato, Isao Okayasu
Pages: 2364-2372
Published online on: 08 December 2017

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Article Open Access

Effects of 16-bit CT imaging scanning conditions for metal implants on radiotherapy dose distribution

Liugang Gao, Hongfei Sun, Xinye Ni, Mingming Fang, Tao Lin
Pages: 2373-2379
Published online on: 11 December 2017

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Article

Association between inflammation and cancer stem cell phenotype in breast cancer

Young Ju Jeong, Hoon Kyu Oh, Sung Hwan Park, Jin Gu Bong
Pages: 2380-2386
Published online on: 13 December 2017

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Article

Granulocyte-colony stimulating factor producing mucinous cystic neoplasm with an associated invasive carcinoma of the pancreas

Kazuhide Shimamatsu, Yoshiki Naito, Yutaro Mihara, Masamichi Nakayama, Masahiko Tanigawa, Yushi Abe, Ken Nakamura, Toshihiro Araki, Kenji Sakata, Kazunori Noguchi, Jun Akiba, Hirohisa Yano, Osamu Nakashima
Pages: 2387-2392
Published online on: 08 December 2017

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Article

Carnosic acid, an inducer of NAD(P)H quinone oxidoreductase 1, enhances the cytotoxicity of β‑lapachone in melanoma cell lines

Nobuyuki Arakawa, Ayaka Okubo, Shinji Yasuhira, Kazuhiro Takahashi, Hiroo Amano, Toshihide Akasaka, Tomoyuki Masuda, Masahiko Shibazaki, Chihaya Maesawa
Pages: 2393-2400
Published online on: 14 December 2017

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Article

Decreased expression of CADM1 and CADM4 are associated with advanced stage breast cancer

Motonobu Saito, Akiteru Goto, Noriko Abe, Katsuharu Saito, Daichi Maeda, Tohru Ohtake, Yoshinori Murakami, Seiichi Takenoshita
Pages: 2401-2406
Published online on: 06 December 2017

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Article

A retrospective study of 34 patients with unicentric and multicentric Castleman's disease: Experience from a single institution

Jin‑Peng Jiang, Xiao‑Fei Shen, Jun‑Feng Du, Wen‑Xian Guan
Pages: 2407-2412
Published online on: 14 December 2017

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Article

Melanocyte-specific gene 1 promotes melanoma progression by enhancing the expression of Bcl-2

Hui Zhao, Guosheng Wu, Ji Zhu, Mengyan Sun, Yuchong Wang, Yongjie Fan, Kai Wu, Hongda Bi, Haiying Dai, Chuan Lv, Chunyu Xue
Pages: 2413-2418
Published online on: 12 December 2017

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Article

Molecular screening and the clinical impacts of BCR‑ABL KD mutations in patients with imatinib‑resistant chronic myeloid leukemia

Betül Koçkan, Tayfur Toptaş, Işik Atagündüz, Ayşe Tülin Tuğlular, Ayşe Özer, Mustafa Akkiprik
Pages: 2419-2424
Published online on: 13 December 2017

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Article

A novel function of NUCB2 in promoting the development and invasion of renal cell carcinoma

Huan Xu, Wenzhi Li, Kai Qi, Juan Zhou, Meng Gu, Zhong Wang
Pages: 2425-2430
Published online on: 08 December 2017

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Article

Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer

Young Ju Jeong, Sung Hwan Park, Sung Hee Mun, Sang Gyu Kwak, Sun‑Jae Lee, Hoon Kyu Oh
Pages: 2431-2440
Published online on: 14 December 2017

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Article

Dynamics of CRISPR/Cas9-mediated genomic editing of the AXL locus in hepatocellular carcinoma cells

Irene Scharf, Lisa Bierbaumer, Heidemarie Huber, Philipp Wittmann, Christine Haider, Christine Pirker, Walter Berger, Wolfgang Mikulits
Pages: 2441-2450
Published online on: 13 December 2017

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Article

Experience-based surgical approach to pancreatic mucinous cystic neoplasms with ovarian-type stroma

Chang Moo Kang, Akira Matsushita, Ho Kyoung Hwang, Yoko Matsuda, Hyunki Kim, Yoshiharu Nakamura, Woo Jung Lee
Pages: 2451-2458
Published online on: 14 December 2017

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Article

Anticancer effects of 10-hydroxycamptothecin induce apoptosis of human osteosarcoma through activating caspase-3, p53 and cytochrome c pathways

Xiong Min, Han Heng, Hua‑Long Yu, Mao Dan, Chen Jie, Yun Zeng, He Ning, Zhi‑Gang Liu , Zhi‑Yong Wang, Wang Lin
Pages: 2459-2464
Published online on: 13 December 2017

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Article

Retrospective observational cohort study on cosmetic outcome of using Ti‑Ni memory alloy wire for intradermal suture following mastectomy in patients with breast cancer

Gang Li, Sida Qin, Xin Sun, Jiansheng Wang, Yunfeng Zhang, Jia Zhang, Jing Zhang, Shou‑Ching Tang, Hong Ren
Pages: 2465-2470
Published online on: 13 December 2017

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Article

Targeting breast cancer cells with a CuInS2/ZnS quantum dot-labeled Ki-67 bioprobe

Guang Sun, Wanying Xing, Ren Xing, Liu Cong, Sun Tong, Siyao Yu
Pages: 2471-2476
Published online on: 14 December 2017

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Article

Effect and molecular mechanism of mTOR inhibitor rapamycin on temozolomide‑induced autophagic death of U251 glioma cells

Bing Li, Chun Zhou, Liang Yi, Lunshan Xu, Minhui Xu
Pages: 2477-2484
Published online on: 06 December 2017

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Article

Electron microscopic analysis of different cell types in human pancreatic cancer spheres

Toshiyuki Ishiwata, Fumio Hasegawa, Masaki Michishita, Norihiko Sasaki, Naoshi Ishikawa, Kaiyo Takubo, Yoko Matsuda, Tomio Arai, Junko Aida
Pages: 2485-2490
Published online on: 08 December 2017

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Article

A rare e14a3 BCR/ABL fusion transcript in acute lymphoblastic leukemia patient treated with CAR-modified T-cell therapy

Haodong Cai, Li Yang, Kefeng Shen, Wei Zhang, Jie Xiong, Meilan Zhang, Xia Mao, Ying Wang, Min Xiao
Pages: 2491-2494
Published online on: 13 December 2017

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Article

Lymph node retrieval after dissolution of surrounding adipose tissue for pathological examination of colorectal cancer

Hiromichi Maeda, Ken Okamoto, Koji Oba, Mai Shiga, Yuki Fujieda, Tsutomu Namikawa, Makoto Hiroi, Ichiro Murakami, Kazuhiro Hanazaki, Michiya Kobayashi
Pages: 2495-2500
Published online on: 14 December 2017

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Article

Expression of CXC-motif-chemokine 12 and the receptor C‑X‑C receptor 4 in glioma and theeffect on peritumoral brain edema

Wenlong Tang, Yupeng Chen, Xingfu Wang, Yao Chen, Jiandong Zhang, Zhixiong Lin
Pages: 2501-2507
Published online on: 08 December 2017

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Article

miR-339-5p inhibits metastasis of non-small cell lung cancer by regulating the epithelial-to-mesenchymal transition

Yun Li, Xuelin Zhang, Zhen Yang, Yanan Li, Baiyu Han, Liang An Chen
Pages: 2508-2514
Published online on: 13 December 2017

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Article

Celastrol suppresses the proliferation of lung adenocarcinoma cells by regulating microRNA-24 and microRNA-181b

Yun‑Fei Yan, Han‑Han Zhang, Qing Lv, Yue‑Mei Liu, You‑Jie Li, Bao‑Sheng Li, Ping‑Yu Wang, Wen‑Jing Shang, Zhen Yue, Shu‑Yang Xie
Pages: 2515-2521
Published online on: 12 December 2017

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Article

Characterization of circulating tumor cells in newly diagnosed breast cancer

Lu Xu, Songlin Jia, Hengyu Li, Yue Yu, Guoping Liu, Yanmei Wu, Xishui Liu, Chaoqian Liu, Yue Zhou, Zhenzhen Zhang, Yuan Sheng
Pages: 2522-2528
Published online on: 06 December 2017

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Case Report

A unique bone marrow lymphoma patient presenting with an isolated mass: A case report

Yi‑Wen Xu, Ming‑Hui Duan
Pages: 2529-2533
Published online on: 06 December 2017

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Article

The expression and underlying angiogenesis effect of DPC4 and VEGF on the progression of cervical carcinoma

Yanni A, Ying Li, Shuping Zhao
Pages: 2534-2540
Published online on: 11 December 2017

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Article

Development and in vitro evaluation of mucoadhesive patches of methotrexate for targeted delivery in oral cancer

Bao‑Zhong Jin, Xiao‑Qi Dong, Xin Xu, Feng‑He Zhang
Pages: 2541-2549
Published online on: 13 December 2017

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Article

Tanshinone II is a potent candidate for treatment of lipopolysaccharide-induced acute lung injury in rat model

Ling Li, Yong‑Gang Zhang, Yu‑Fei Tan, Jing‑Jing Zhao, Hua‑Ru Zhang, Bing Zhao
Pages: 2550-2554
Published online on: 11 December 2017

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Article

Therapeutic effect of targeted Fas-expressing adenoviruses method combining γδ T cells in a mouse model of human ovarian carcinoma

Dingyuan Zeng, Jiajing Lin, Hongying He, Guangping Tan, Ying Lan, Fuyan Jiang, Shuting Sheng
Pages: 2555-2561
Published online on: 13 December 2017

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Article

Dihydroartemisinin treatment of multiple myeloma cells causes activation of c-Jun leading to cell apoptosis

Yong Wang, Xiaoyuan Xu, Xiaojian Wu, Weibin Chen, Fangmei Huang, Xiaomin Gui
Pages: 2562-2566
Published online on: 11 December 2017

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Article

Validation of the novel susceptibility loci for prostate cancer in a Chinese population

Yishuo Wu, Haitao Chen, Ying Ji, Rong Na, Zengnan Mo, Dingwei Ye, Meilin Wang, Jun Qi, Xiaoling Lin, Qiang Ding, Jianfeng Xu, S. Lilly Zheng, Yinghao Sun, Wei Meng
Pages: 2567-2573
Published online on: 13 December 2017

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Article

Prediction of long‑term survival rates in patients undergoing curative resection for solitary hepatocellular carcinoma

Yi Cao, Zhelong Jiang, Shaohu Wang, Haoyang Zhang, Yi Jiang, Lizhi Lv
Pages: 2574-2582
Published online on: 13 December 2017

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Article

Neddylation inhibitor MLN4924 induces G2 cell cycle arrest, DNA damage and sensitizes esophageal squamous cell carcinoma cells to cisplatin

Shan Lin, Zhaoyang Shang, Shuo Li, Peng Gao, Yi Zhang, Shuaiheng Hou, Peng Qin, Ziming Dong, Tao Hu, Ping Chen
Pages: 2583-2589
Published online on: 14 December 2017

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Article

Activin A induces apoptosis of mouse myeloma cells via the mitochondrial pathway

Yuanyi Zhang, Yan Qi, Yang Zhao, Hongyan Sun, Jingyan Ge, Zhonghui Liu
Pages: 2590-2594
Published online on: 11 December 2017

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Article

LATS2 promoter hypermethylation and its effect on gene expression in human breast cancer

Saki Matsui, Naofumi Kagara, Chieko Mishima, Yasuto Naoi, Masafumi Shimoda, Atsushi Shimomura, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi
Pages: 2595-2603
Published online on: 06 December 2017

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Article

Augmentation of antibody-dependent cellular cytotoxicity with defucosylated monoclonal antibodies in patients with GI-tract cancer

Takahiro Nakajima, Hirokazu Okayama, Mai Ashizawa, Masaru Noda, Keita Aoto, Motonobu Saito, Tomoyuki Monma, Shinji Ohki, Masahiko Shibata, Seiichi Takenoshita, Koji Kono
Pages: 2604-2610
Published online on: 08 December 2017

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Article

3‑Oxoacid CoA transferase 1 as a therapeutic target gene for cisplatin-resistant ovarian cancer

San‑Duk Yang, So Hee Ahn, Jong‑Il Kim
Pages: 2611-2618
Published online on: 08 December 2017

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Article

Genipin inhibits the growth of human bladder cancer cells via inactivation of PI3K/Akt signaling

Zheng Li, Tian‑Biao Zhang, Dong‑Hui Jia, Wen‑Qi Sun, Chao‑Liang Wang, Ao‑Zheng Gu, Xiao‑Ming Yang
Pages: 2619-2624
Published online on: 11 December 2017

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Article

Analysis of expression profile data identifies key genes and pathways in hepatocellular carcinoma

Xuwei Jiang, Yuqing Hao
Pages: 2625-2630
Published online on: 06 December 2017

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Article

Antitumor effect of membrane-type Tim-3 on hepatocellular carcinoma Hepa1-6 cells of ICR mice

Ju Liu, Haiying Sun, Dan Shen, Mingmin Wang, Zirong Wen
Pages: 2631-2634
Published online on: 14 December 2017

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Article

Capture of mesothelioma cells with ‘universal’ CTC-chip

Kazue Yoneda, Yasuhiro Chikaishi, Taiji Kuwata, Takashi Ohnaga, Fumihiro Tanaka
Pages: 2635-2640
Published online on: 14 December 2017

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Article

Association between clinicopathological factors and postoperative radiotherapy in patients with completely resected pathological N2 non-small cell lung cancer

Yujin Xu, Jianqiang Li, Jin Wang, Xiao Hu, Honglian Ma, Pu Li, Xiao Zheng, Ming Chen
Pages: 2641-2650
Published online on: 13 December 2017

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Article

Acridone suppresses the proliferation of human breast cancer cells in vitro via ATP-binding cassette subfamily G member 2

Licheng Xu, Shuyan Li, Zhi Liang, Haixia Lin, Rongzhan Fu
Pages: 2651-2654
Published online on: 11 December 2017

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Article

The effects of hemocyanin on T cells cultured in vitro

Jiani Liu, Cong Chen, Chen Ling, Haoyun Hu, Jingsong Cao, Yongqiang Gao
Pages: 2655-2660
Published online on: 11 December 2017

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Article

Expression and potential mechanism of metabolism-related genes and CRLS1 in non-small cell lung cancer

Hai‑Ming Feng, Ye Zhao, Jian‑Ping Zhang, Jian‑Hua Zhang, Peng Jiang, Bin Li, Cheng Wang
Pages: 2661-2668
Published online on: 12 December 2017

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Article

Abiraterone acetate withdrawal syndrome: Speculations on the underlying mechanisms

Tomonori Kato, Akira Komiya, Joji Yuasa, Kanya Kaga, Mayuko Kaga, Satoko Kojima, Yukio Naya, Shigeo Isaka
Pages: 2669-2672
Published online on: 14 December 2017

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Article

Mechanism of the anti-angiogenic effect of Avemar on tumor cells

Nilüfer Gülmen Imir, Esra Aydemir, Ece Şimşek
Pages: 2673-2678
Published online on: 13 December 2017

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Article

Salvianolic acid B suppresses cell proliferation and induces apoptosis in osteosarcoma through p38-mediated reactive oxygen species generation

Zhaoyang Zeng, Hua Zhang, Xin Wang, Kai Liu, Tian Li, Shaobo Sun, Hailong Li
Pages: 2679-2685
Published online on: 13 December 2017

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Article

Prediction of decannulation, oral intake recovery, overall survival and lung metastasis following oral malignant tumor resection and reconstruction

Hidenori Suzuki, Ikuo Hyodo, Yasuhisa Hasegawa
Pages: 2686-2694
Published online on: 11 December 2017

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Article

MicroRNA-122-3p inhibits tumor cell proliferation and induces apoptosis by targeting Forkhead box O in A549 cells

Wen Wang, Jinsong Yang, Fenglei Yu, Wenjie Li, Li Wang, Haoyu Zou, Xia Long
Pages: 2695-2699
Published online on: 11 December 2017

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Article

Overexpression of centrosomal protein 55 regulates the proliferation of glioma cell and mediates proliferation promoted by EGFRvIII in glioblastoma U251 cells

Hongfan Zhu, Diangang Chen, Jinliang Tang, Changlin Huang, Shengqing Lv, Donglin Wang, Guanghui Li
Pages: 2700-2706
Published online on: 08 December 2017

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Correction Open Access

[Corrigendum] A proposed method for the relative quantification of levels of circulating microRNAs in the plasma of gastric cancer patients

Mayra‑Cecilia Suárez‑Arriaga, Javier Torres, Margarita Camorlinga‑Ponce, Alejandro Gómez‑Delgado, Patricia Piña‑Sánchez, Hilda‑Alicia Valdez‑Salazar, Rosa‑María Ribas‑Aparicio, Ezequiel M. Fuentes‑Pananá, Martha‑Eugenia Ruiz‑Tachiquín
Pages: 2707-2707
Published online on: 14 December 2017

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Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu-Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
Article Number: 321
Published online on: 02 June 2026

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Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
Published online on: 02 June 2026

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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Article Open Access

Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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