Retrospective observational cohort study on cosmetic outcome of using Ti‑Ni memory alloy wire for intradermal suture following mastectomy in patients with breast cancer

Li,Gang; Qin,Sida; Sun,Xin; Wang,Jiansheng; Zhang,Yunfeng; Zhang,Jia; Zhang,Jing; Tang,Shou‑Ching; Ren,Hong

doi:10.3892/ol.2017.7603

Retrospective observational cohort study on cosmetic outcome of using Ti‑Ni memory alloy wire for intradermal suture following mastectomy in patients with breast cancer

Authors:
- Gang Li
- Sida Qin
- Xin Sun
- Jiansheng Wang
- Yunfeng Zhang
- Jia Zhang
- Jing Zhang
- Shou‑Ching Tang
- Hong Ren
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Affiliations: Department of Thoracic Surgery and Oncology, Cancer Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xian, Shaanxi 710061, P.R. China, Division of Hematology and Oncology, The Georgia Cancer Center, Augusta University, Augusta, GA 30912, USA
Published online on: December 13, 2017 https://doi.org/10.3892/ol.2017.7603
Pages: 2465-2470

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Abstract

The method of suturing for incisions is crucial for the comprehensive treatment of clinical patients with breast cancer. Suturing is considered a major part of post‑surgical recovery and may serve as a marker for evaluation of surgical outcome. The present study aimed to establish an effective means of suturing for patients who received modified radical surgery that helps to improve the cosmetic outcome of the incision. Enrolled patients were divided into an active and a control group. Ti‑Ni memory alloy wire for intradermal suture in the active group and silk for interruption suture in the control group were applied to assess the different prognosis‑associated factors. The Vancouver Scar Scale (VSS) was used to evaluate the wound size and the recovery time of the scars. The association between diabetes and the number of days of wound healing was also analyzed. The results indicated that the mean VSS score of the active group was decreased compared with that of the control group (P<0.001). The VSS scores of four main features (vascularity, pigmentation, pliability and height) between the two groups also statistically differed (P<0.001). Furthermore, the mean number of days of wound healing was significantly decreased for the active group compared with that for the control group (P=0.0026) in the patients with diabetes. In addition, the usage of Ti‑Ni memory alloy wire was able to decrease the mean number of wound healing days between patients with diabetes and their non‑diabetic counterparts (P=0.7009). The present study indicated that intradermal suture offers improved cosmetic outcome for patients undergoing mastectomy with or without axillary surgery. This technique may be useful for preventing scar overgrowth and for facilitating the recovery process in patients with diabetes.

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