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Article Open Access

Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer

  • Authors:
    • Yi Li
    • Ji Wang
    • Li Tan
    • Beina Hui
    • Xiaowei Ma
    • Yanli Yan
    • Chaofan Xue
    • Xiaoting Shi
    • Emmanuel Kwateng Drokow
    • Juan Ren
  • View Affiliations / Copyright

    Affiliations: Department of Radiotherapy, Oncology Department, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China, Intensive Care Unit, China Meitan General Hospital, Beijing 100028, P.R. China, Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China
    Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3735-3745
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    Published online on: January 4, 2018
       https://doi.org/10.3892/ol.2018.7732
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Abstract

The aim of the present study was to compare inte­nsity‑modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) in irradiation of lung cancer. Plans of 14 patients were compared. The results demonstrated that in peripheral lung cancer, V5 (%) of the lung in partial‑arc (PA)‑VMAT was decreased compared with IMRT, single‑arc (SA)‑, and double partial‑arc (2PA)‑VMAT. V30 (%) of the lung in IMRT was decreased compared with SA‑, PA‑ and 2PA‑VMAT. In the case of planning target volume (PTV) not encompassing the mediastinum in central lung cancer, the conformality index (CI) and heterogeneity index (HI) of SA‑VMAT was improved compared with IMRT, PA‑, and 2PA‑VMAT. The received dose of heart in SA‑VMAT was higher compared with IMRT, PA‑ and 2PA‑VMAT. V30 (%) and V5 (%) of the lung in IMRT was higher compared with SA‑, PA‑ and 2PA‑VMAT; V10 (%) of the lung in 2PA was decreased compared with IMRT, SA‑ and PA. In the case of PTV encompassing the mediastinum in central lung cancer, the HI and CI of 2PA was improved compared with IMRT, SA‑ and PA‑VMAT. The received dose of heart in 2PA was higher compared with IMRT, SA‑ and PA‑VMAT. V30 (%) and V5 (%) of the lung in 2PA‑VMAT was higher compared with IMRT, SA‑ and PA‑VMAT. V20 (%) of the lung in 2PA was decreased compared with IMRT, SA‑ and PA‑VMAT. In conclusion, it may be necessary to classify the radiotherapy plans of lung cancer into three categories including peripheral lung cancer, PTV not encompassing the mediastinum of central lung cancer, and PTV encompassing the mediastinum of central lung cancer. Each of IMRT, SA‑VMAT, PA‑VMAT, 2PA‑VMAT strategy had individual advantages, and therefore it may be crucial to employ different planning techniques for different disease classifications and OAR requirements.
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Copy and paste a formatted citation
Spandidos Publications style
Li Y, Wang J, Tan L, Hui B, Ma X, Yan Y, Xue C, Shi X, Drokow EK, Ren J, Ren J, et al: Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer. Oncol Lett 15: 3735-3745, 2018.
APA
Li, Y., Wang, J., Tan, L., Hui, B., Ma, X., Yan, Y. ... Ren, J. (2018). Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer. Oncology Letters, 15, 3735-3745. https://doi.org/10.3892/ol.2018.7732
MLA
Li, Y., Wang, J., Tan, L., Hui, B., Ma, X., Yan, Y., Xue, C., Shi, X., Drokow, E. K., Ren, J."Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer". Oncology Letters 15.3 (2018): 3735-3745.
Chicago
Li, Y., Wang, J., Tan, L., Hui, B., Ma, X., Yan, Y., Xue, C., Shi, X., Drokow, E. K., Ren, J."Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer". Oncology Letters 15, no. 3 (2018): 3735-3745. https://doi.org/10.3892/ol.2018.7732
Copy and paste a formatted citation
x
Spandidos Publications style
Li Y, Wang J, Tan L, Hui B, Ma X, Yan Y, Xue C, Shi X, Drokow EK, Ren J, Ren J, et al: Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer. Oncol Lett 15: 3735-3745, 2018.
APA
Li, Y., Wang, J., Tan, L., Hui, B., Ma, X., Yan, Y. ... Ren, J. (2018). Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer. Oncology Letters, 15, 3735-3745. https://doi.org/10.3892/ol.2018.7732
MLA
Li, Y., Wang, J., Tan, L., Hui, B., Ma, X., Yan, Y., Xue, C., Shi, X., Drokow, E. K., Ren, J."Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer". Oncology Letters 15.3 (2018): 3735-3745.
Chicago
Li, Y., Wang, J., Tan, L., Hui, B., Ma, X., Yan, Y., Xue, C., Shi, X., Drokow, E. K., Ren, J."Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer". Oncology Letters 15, no. 3 (2018): 3735-3745. https://doi.org/10.3892/ol.2018.7732
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