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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2018 Volume 15 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Molecular challenges of neuroendocrine tumors (Review)

Parthik Patel, Karina Galoian
Pages: 2715-2725
Published online on: 21 December 2017

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Review

Function of Axl receptor tyrosine kinase in non-small cell lung cancer (Review)

Guoan Zhang, Meng Wang, Hongli Zhao, Wen Cui
Pages: 2726-2734
Published online on: 27 December 2017

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Review

MicroRNAs and cancer: Key paradigms in molecular therapy (Review)

Weige Tan, Bodu Liu, Shaohua Qu, Gehao Liang, Wei Luo, Chang Gong
Pages: 2735-2742
Published online on: 19 December 2017

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Review

Functions of nuclear actin-binding proteins in human cancer (Review)

Xinyi Yang, Ying Lin
Pages: 2743-2748
Published online on: 19 December 2017

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Review

Glucagonoma and the glucagonoma syndrome (Review)

Xujun Song, Suli Zheng, Gang Yang, Guangbing Xiong, Zhe Cao, Mengyu Feng, Taiping Zhang, Yupei Zhao
Pages: 2749-2755
Published online on: 28 December 2017

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Article Open Access

Upregulated HOXA9 expression is associated with lymph node metastasis in colorectal cancer

Yohei Watanabe, Motonobu Saito, Katsuharu Saito, Yoshiko Matsumoto, Yasuyuki Kanke, Hisashi Onozawa, Suguru Hayase, Wataru Sakamoto, Teruhide Ishigame, Tomoyuki Momma, Shinji Ohki, Seiichi Takenoshita
Pages: 2756-2762
Published online on: 19 December 2017

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Article Open Access

TERT promoter mutations and their correlation with BRAF and RAS mutations in a consecutive cohort of 145 thyroid cancer cases

Andrea Cacciato Insilla, Agnese Proietti, Nicla Borrelli, Elisabetta Macerola, Cristina Niccoli, Paolo Vitti, Paolo Miccoli, Fulvio Basolo
Pages: 2763-2770
Published online on: 21 December 2017

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Article Open Access

Opposite response to hypoxia by breast cancer cells between cell proliferation and cell migration: A clue from microRNA expression profile

Ming Zhang, Chang‑E Gao, Wen‑Lin Chen, Yi‑Yin Tang, Jian‑Yun Nie, Li‑Da Shen, Xiang Ma, De‑Dian Chen
Pages: 2771-2780
Published online on: 19 December 2017

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Article Open Access

Deregulation of microRNA-193b affects the proliferation of liver cancer via myeloid cell leukemia-1

Wenjun Yin, Yuehua Nie, Lingying Chen, Quipping Wang, Shuangquan Liu, Xiusheng He, Wenjun Wang
Pages: 2781-2788
Published online on: 27 December 2017

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Article Open Access

Identification and analysis of key genes in osteosarcoma using bioinformatics

Chunyu Diao, Yong Xi, Tao Xiao
Pages: 2789-2794
Published online on: 19 December 2017

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Article Open Access

PRL-3 promotes breast cancer progression by downregulating p14ARF-mediated p53 expression

Hua Xie, Hao Wang
Pages: 2795-2800
Published online on: 19 December 2017

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Article Open Access

Dexamethasone induced apoptosis of A549 cells via the TGF-β1/Smad2 pathway

Xiao‑Ling Feng, Hui‑Zhi Fei, Ling Hu
Pages: 2801-2806
Published online on: 27 December 2017

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Article Open Access

Bioinformatical analysis of gene expression signatures of different glioma subtypes

Rui Wang, Jun Wei, Zhaohui Li, Yu Tian, Chao Du
Pages: 2807-2814
Published online on: 20 December 2017

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Article Open Access

Karyopherin subunit-α 2 expression accelerates cell cycle progression by upregulating CCNB2 and CDK1 in hepatocellular carcinoma

Chun‑Lin Gao, Gao‑Wei Wang, Guan‑Qin Yang, Hong Yang, Li Zhuang
Pages: 2815-2820
Published online on: 27 December 2017

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Article Open Access

Induction of apoptosis by an oleanolic acid derivative in SMMC-7721 human hepatocellular carcinoma cells is associated with mitochondrial dysfunction

Xinfeng Fan, Penglong Wang, Yaogui Sun, Junbing Jiang, Haiyuan Du, Zhirui Wang, Zhibian Duan, Haimin Lei, Hongquan Li
Pages: 2821-2828
Published online on: 19 December 2017

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Article Open Access

Lentivirus-mediated silencing of HOTAIR lncRNA restores gefitinib sensitivity by activating Bax/Caspase-3 and suppressing TGF-α/EGFR signaling in lung adenocarcinoma

Yuanshun Liu, Hua Jiang, Hongbin Zhou, Xiwang Ying, Zhehua Wang, Yang Yang, Wulin Xu, Xujun He, Yaqing Li
Pages: 2829-2838
Published online on: 19 December 2017

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Article Open Access

Chloroquine potentiates the anticancer effect of sunitinib on renal cell carcinoma by inhibiting autophagy and inducing apoptosis Corrigendum in /10.3892/ol.2024.14403

Man‑Li Li, You‑Zhi Xu, Wen‑Jie Lu, Yong‑Huai Li, Shi‑Sheng Tan, Hong‑Jun Lin, Tian‑Ming Wu, Yan Li, Si‑Ying Wang, Ying‑Lan Zhao
Pages: 2839-2846
Published online on: 19 December 2017

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Article Open Access

Short interfering RNA-mediated silencing of actin-related protein 2/3 complex subunit 4 inhibits the migration of SW620 human colorectal cancer cells

Xiaojuan Su, Siyang Wang, Yongxu Huo, Chunlei Yang
Pages: 2847-2854
Published online on: 19 December 2017

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Article Open Access

Estrogen receptor-α promoter methylation is a biomarker for outcome prediction of cisplatin resistance in triple-negative breast cancer

Junnan Xu, Tao Sun, Xiangyu Guo, Yan Wang, Mingxi Jing
Pages: 2855-2862
Published online on: 19 December 2017

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Article Open Access

MicroRNA‑9 functions as a tumor suppressor and enhances radio‑sensitivity in radio‑resistant A549 cells by targeting neuropilin 1

Kai Xiong, Li Hong Shao, Hai Qin Zhang, Linlin Jin, Wei Wei, Zhuo Dong, Yue Quan Zhu, Ning Wu, Shun Zi Jin, Li Xiang Xue
Pages: 2863-2870
Published online on: 28 December 2017

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Article Open Access

Enhancement of cisplatin cytotoxicity by Retigeric acid B involves blocking DNA repair and activating DR5 in prostate cancer cells

Yongqing Liu, Chunwen Yue, Juan Li, Jing Wu, Shikang Wang, Deqing Sun, Yanxia Guo, Zhaomin Lin, Denglu Zhang, Rongmei Wang
Pages: 2871-2880
Published online on: 20 December 2017

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Article Open Access

Mitochondrial ROS contribute to oridonin-induced HepG2 apoptosis through PARP activation

Xiaoning Liu, Jingjing Kang, Hui Wang, Tao Huang
Pages: 2881-2888
Published online on: 20 December 2017

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Article Open Access

Phosphoproteomic analysis of the antitumor effects of ginsenoside Rg3 in human breast cancer cells

Mingjin Zou, Jing Wang, Jidong Gao, Hui Han, Yi Fang
Pages: 2889-2898
Published online on: 19 December 2017

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Article Open Access

Cranial irradiation inhibits hippocampal neurogenesis via DNMT1 and DNMT3A

Shengjun Ji, Xin Ding, Jiang Ji, Haohao Wu, Rui Sun, Xiaoyang Li, Liyuan Zhang, Ye Tian
Pages: 2899-2904
Published online on: 19 December 2017

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Article Open Access

A novel ARMS-based assay for the quantification of EGFR mutations in patients with lung adenocarcinoma

Yazhen Zhu, Zhiwei Guo, Ying Liu, Xiyun Zheng, Guohua Yang, Guangjuan Zheng
Pages: 2905-2912
Published online on: 21 December 2017

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Article Open Access

Thermographic real-time-monitoring of surgical radiofrequency and microwave ablation in a perfused porcine liver model

Florian Primavesi, Stefan Swierczynski, Eckhard Klieser, Tobias Kiesslich, Tarkan Jäger, Romana Urbas, Jörg Hutter, Daniel Neureiter, Dietmar Öfner, Stefan Stättner
Pages: 2913-2920
Published online on: 18 December 2017

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Article Open Access

NAC1 promotes the migration of prostate cancer cells and participates in osteoclastogenesis by negatively regulating IFNβ

Fang Chen, Yinghao Yin, Zhifeng Yan, Ke Cao, Kuangbiao Zhong
Pages: 2921-2928
Published online on: 20 December 2017

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Article Open Access

Analysis of the effect of laparoscopy and hysteroscopy on ovarian function, immune function and quality of sexual life of patients with hysteromyoma at different ages

Yuxue Zhang, Xiaoli Gu, Yuejin Meng, Haizhou Guo, Jiehua Du, Wei Xing
Pages: 2929-2934
Published online on: 15 December 2017

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Article Open Access

Long‑lasting memory of cellular immunity in a chronic myeloid leukemia patient maintains molecular response 5 after cessation of dasatinib

Tatsuro Jo, Kazuhiro Noguchi, Shizuka Hayashi, Sadaharu Irie, Risa Hayase, Haruna Shioya, Youhei Kaneko, Kensuke Horio, Jun Taguchi
Pages: 2935-2938
Published online on: 29 December 2017

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Article Open Access

Metformin inhibits the migration and invasion of esophageal squamous cell carcinoma cells by downregulating the protein kinase B signaling pathway

Yindi He, Xiaojun Tan, Hui Hu, Qinjia Wang, Xi Hu, Xianbin Cai, Yinghong Guan, Binming Chen, Xubin Jing
Pages: 2939-2945
Published online on: 28 December 2017

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Case Report Open Access

Primary malignant perivascular epithelioid cell neoplasm (PEComa) of the bone mimicking granular cell tumor in core biopsy: A case report and literature review

Sam Sadigh, Preya Shah, Kristy Weber, Ronnie Sebro, Paul J. Zhang
Pages: 2946-2952
Published online on: 20 December 2017

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Article Open Access

Expression of EZH2 is associated with poor outcome in colorectal cancer

Zhuanpeng Chen, Ping Yang, Wanglin Li, Feng He, Jianchang Wei, Tong Zhang, Junbin Zhong, Huacui Chen, Jie Cao
Pages: 2953-2961
Published online on: 19 December 2017

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Article Open Access

Bromelain has significant clinical benefits after extraction of the third molar during chemotherapy in patients with hematologic tumor

Yi Tan, Ping Li
Pages: 2962-2966
Published online on: 20 December 2017

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Article Open Access

DHA induces apoptosis of human malignant breast cancer tissues by the TLR‑4/PPAR‑α pathways

Lijing Geng, Wei Zhou, Bing Liu, Xinyun Wang, Bo Chen
Pages: 2967-2977
Published online on: 28 December 2017

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Article Open Access

Dynamics of angiogenesis and cellularity in rabbit VX2 tumors using contrast-enhanced magnetic resonance imaging and diffusion-weighted imaging

Haixia Li, Lijuan Yu, Wenzhi Wang, Lingling Wang, Xiulan Zheng, Shaochun Dai, Yanqin Sun
Pages: 2978-2984
Published online on: 19 December 2017

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Article Open Access

CD133 expression and α‑fetoprotein levels define novel prognostic subtypes of HBV‑associated hepatocellular carcinoma: A long‑term follow‑up analysis

Xiao‑Meng Dai, Sheng‑Li Yang, Xiu‑Mei Zheng, George G. Chen, Jing Chen, Tao Zhang
Pages: 2985-2991
Published online on: 28 December 2017

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Article Open Access

Nucleotide variation in ATG4A and susceptibility to cervical cancer in Southwestern Chinese women

Jin‑Ju Mao, Li‑Xiang Wu, Wei Wang, Yuan‑Yuan Ye, Jun Yang, Hong Chen, Qian‑Fan Yang, Xiu‑Yu Zhang, Bo Wang, Wei‑Xian Chen
Pages: 2992-3000
Published online on: 20 December 2017

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Article Open Access

Focal adhesion kinase is overexpressed in thymic epithelial tumors and may serve as an independent prognostic biomarker

Meng Li, Feng Hou, Jie Zhao, Tianqiang Zhang, Dongfei Li, Wensi Wu, Xiaotong Liu, Linhao Xu
Pages: 3001-3007
Published online on: 21 December 2017

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Article Open Access

Analysis of radiation effects in two irradiated tumor spheroid models

Afkar Al‑Ramadan, Anja C. Mortensen, Jörgen Carlsson, Marika V. Nestor
Pages: 3008-3016
Published online on: 29 December 2017

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Article Open Access

Bioinformatics identification of dysregulated microRNAs in triple negative breast cancer based on microRNA expression profiling

Junqing Chen, Zhanhong Chen, Jian Huang, Feng Chen, Weiwu Ye, Guojun Ding, Xiaojia Wang
Pages: 3017-3023
Published online on: 28 December 2017

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Article Open Access

Prognostic significance of sodium-potassium ATPase regulator, FXYD3, in human hepatocellular carcinoma

Li‑Juan Wang, Qi‑Jiong Li, Yong Le, Han‑Yue Ouyang, Min‑Ke He, Zi‑Shan Yu, Yong‑Fa Zhang, Ming Shi
Pages: 3024-3030
Published online on: 21 December 2017

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Article Open Access

Gadd45β silencing impaired viability and metastatic phenotypes in cholangiocarcinoma cells by modulating the EMT pathway

Kyaw Zwar Myint, Pornparn Kongpracha, Panthip Rattanasinganchan, Kawin Leelawat, Penpak Moolthiya, Kittipong Chaiyabutr, Rutaiwan Tohtong
Pages: 3031-3041
Published online on: 28 December 2017

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Article Open Access

Expression of proteins associated with epithelial‑mesenchymal transition in esophageal squamous cell carcinoma

Tian Zhang, Hao Li, Yang Zhang, Pei Wang, Huijie Bian, Zhi‑Nan Chen
Pages: 3042-3048
Published online on: 28 December 2017

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Article Open Access

Long non-coding RNA cartilage injury-related promotes malignancy in bladder cancer

Xuebao Xiang, Jiefu Huang, Wenfa Mo, Leiming Jiang, Wenguo Sun, Pengcheng Li
Pages: 3049-3055
Published online on: 21 December 2017

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Article Open Access

Analysis of the association of the expression of KiSS-1 in colorectal cancer tissues with the pathology and prognosis

Xinkai Huo, Lei Zhang, Tao Li
Pages: 3056-3060
Published online on: 15 December 2017

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Article Open Access

High expression of carcinoembryonic antigen and telomerase reverse transcriptase in circulating tumor cells is associated with poor clinical response to the immune checkpoint inhibitor nivolumab

Halin Bao, Tuya Bai, Koji Takata, Takehiko Yokobori, Takashi Ohnaga, Takeshi Hisada, Toshitaka Maeno, Pinjie Bao, Tomonori Yoshida, Yuji Kumakura, Hiroaki Honjo, Makoto Sakai, Makoto Sohda, Minoru Fukuchi, Bolag Altan, Tadashi Handa, Munenori Ide, Tatsuya Miyazaki, Kyoichi Ogata, Tetsunari Oyama, Kimihiro Shimizu, Akira Mogi, Takayuki Asao, Ken Shirabe, Hiroyuki Kuwano, Kyoichi Kaira
Pages: 3061-3067
Published online on: 20 December 2017

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Article Open Access

Characterization of mutations in BRCA1/2 and the relationship with clinic‑pathological features of breast cancer in a hereditarily high‑risk sample of chinese population

Min Fang, Li Zhu, Hengyu Li, Xizhou Li, Yanmei Wu, Kainan Wu, Jian Lin, Yuan Sheng, Yue Yu
Pages: 3068-3074
Published online on: 29 December 2017

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Article

miR-494 inhibits cervical cancer cell proliferation through upregulation of SOCS6 expression

Lei Cheng, Beihua Kong, Ying Zhao, Jie Jiang
Pages: 3075-3080
Published online on: 19 December 2017

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Article

Prostate stem cell antigen is expressed in normal and malignant human brain tissues

Hiroe Ono, Hiromi Sakamoto, Teruhiko Yoshida, Norihisa Saeki
Pages: 3081-3084
Published online on: 18 December 2017

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Article

TBX2 expression is associated with platinum‑sensitivity of ovarian serous carcinoma

Reiko Tasaka, Takeshi Fukuda, Masahiro Shimomura, Yuta Inoue, Takuma Wada, Masaru Kawanishi, Tomoyo Yasui, Toshiyuki Sumi
Pages: 3085-3090
Published online on: 29 December 2017

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Article

Investigation into metastatic processes and the therapeutic effects of gemcitabine on human pancreatic cancer using an orthotopic SUIT‑2 pancreatic cancer mouse model

Tamami Higuchi, Takehiko Yokobori, Tomoharu Naito, Chihaya Kakinuma, Shinji Hagiwara, Masahiko Nishiyama, Takayuki Asao
Pages: 3091-3099
Published online on: 29 December 2017

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Article

Wnt3a expression is associated with poor prognosis of esophageal squamous cell carcinoma

Junya Oguma, Soji Ozawa, Akihito Kazuno, Miho Nitta, Yamato Ninomiya, Hiroshi Kajiwara
Pages: 3100-3108
Published online on: 20 December 2017

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Article

Soft-shelled turtle peptide modulates microRNA profile in human gastric cancer AGS cells

Yi‑Chen Wu, Xiang Liu, Jiu‑Li Wang, Xiang‑Liu Chen, Lan Lei, Jing Han, You‑Shui Jiang, Zhi‑Qiang Ling
Pages: 3109-3120
Published online on: 27 December 2017

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Article

The protective effects of rutaecarpine on acute pancreatitis

Lu Yan, Qing‑Fu Li, Yan‑Ting Rong, Yong‑Heng Chen, Zhao‑Hong Huang, Zhi‑Zhi Wang, Jie Peng
Pages: 3121-3126
Published online on: 20 December 2017

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Article

Effect of silencing colon cancer-associated transcript 2 on the proliferation, apoptosis and autophagy of gastric cancer BGC-823 cells

Zhao‑Yan Yu, Zi Wang, Ke‑Yue Lee, Ping Yuan, Jie Ding
Pages: 3127-3132
Published online on: 21 December 2017

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Article

GTSF1 gene may serve as a novel potential diagnostic biomarker for liver cancer

De‑Yong Gao, Yun Ling, Xiao‑Li Lou, Ying‑Ying Wang, Liang‑Ming Liu
Pages: 3133-3140
Published online on: 27 December 2017

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Article

Luteinizing hormone compromises the in vivo anti-tumor effect of cisplatin on human epithelial ovarian cancer cells

Yan Huang, Yuqi Zhou, Lingfang Xia, Jia Tang, Hao Wen, Meiqin Zhang
Pages: 3141-3146
Published online on: 19 December 2017

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Article

MED28 increases the colony‑forming ability of breast cancer cells by stabilizing the ZNF224 protein upon DNA damage

Jin Gu Cho, Key‑Hwan Lim, Sang Gyu Park
Pages: 3147-3154
Published online on: 29 December 2017

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Article

Actein inhibits cell proliferation and migration and promotes cell apoptosis in human non-small cell lung cancer cells

Yuanyuan Zhang, Jianchun Lian, Xiaowei Wang
Pages: 3155-3160
Published online on: 20 December 2017

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Article

Mutations in KRAS codon 12 predict poor survival in Chinese patients with metastatic colorectal cancer

Bingjun Bai, Lina Shan, Binbin Xie, Xuefeng Huang, Weifang Mao, Xiaowei Wang, Da Wang, Hongbo Zhu
Pages: 3161-3166
Published online on: 28 December 2017

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Article

Simvastatin in combination with meclofenamic acid inhibits the proliferation and migration of human prostate cancer PC‑3 cells via an AKR1C3 mechanism

Yoshitaka Sekine, Hiroshi Nakayama, Yoshiyuki Miyazawa, Haruo Kato, Yosuke Furuya, Seiji Arai, Hidekazu Koike, Hiroshi Matsui, Yasuhiro Shibata, Kazuto Ito, Kazuhiro Suzuki
Pages: 3167-3172
Published online on: 29 December 2017

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Article

RKIP and peroxiredoxin 2 expression predicts the proliferative potential of gastric cancer stem cells

Shao‑Feng Yang, Ran Ma, Li‑Li Pan, Jing Cao, Nan Sheng
Pages: 3173-3177
Published online on: 28 December 2017

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Article

Dihydroartemisinin-induced apoptosis in human acute monocytic leukemia cells

Jia‑Tian Cao, Hui‑Min Mo, Yue Wang, Kai Zhao, Tian‑Tian Zhang, Chang‑Qian Wang, Kai‑Lin Xu, Zhi‑Hua Han
Pages: 3178-3184
Published online on: 19 December 2017

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Article

Interference of P-REX2a may inhibit proliferation and reverse the resistance of SGC7901 cells to doxorubicin

Yaowei Ai, Qiaohui Zhou, Ling Li, Zhihong Pan, Mingwen Guo, Jingbo Han
Pages: 3185-3191
Published online on: 27 December 2017

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Article

Furin inhibitor D6R suppresses epithelial-mesenchymal transition in SW1990 and PaTu8988 cells via the Hippo-YAP signaling pathway

Meng Zhou, Youli Zhang, Hong Wei, Junbo He, Dawei Wang, Baoding Chen, Jian Zeng, Aihua Gong, Min Xu
Pages: 3192-3196
Published online on: 20 December 2017

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Article

mir‑106a regulates cell proliferation and apoptosis of colon cancer cells through targeting the PTEN/PI3K/AKT signaling pathway

Yan Qin, Zhibin Huo, Xiang Song, Xiao Chen, Xiaopeng Tian, Xinjie Wang
Pages: 3197-3201
Published online on: 29 December 2017

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Article

Ursolic acid activates the apoptosis of prostate cancer via ROCK/PTEN mediated mitochondrial translocation of cofilin-1

Dawei Mu, Gaobiao Zhou, Jianye Li, Bin Su, Heqing Guo
Pages: 3202-3206
Published online on: 27 December 2017

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Article

MACC1 and HGF are associated with survival in patients with gastric cancer

Guokai Dong, Man Wang, Guangfu Gu, Shanshan Li, Xiaoming Sun, Zhouru Li, Hongxing Cai, Zhengqiu Zhu
Pages: 3207-3213
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Article

Screening of FOXD3 targets in lung cancer via bioinformatics analysis

Wenhua Jiang, Pengfei Liu, Xiaodong Li
Pages: 3214-3220
Published online on: 21 December 2017

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Article

Beclin-1 knockdown decreases proliferation, invasion and migration of Ewing sarcoma SK-ES-1 cells via inhibition of MMP-9 Corrigendum in /10.3892/ol.2020.12372

Conglin Ye, Xiaolong Yu, Xuqiang Liu, Ping Zhan, Tao Nie, Runsheng Guo, Hucheng Liu, Min Dai, Bin Zhang
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Article

Downregulated cytoplasmic polyadenylation element-binding protein-4 is associated with the carcinogenesis of head and neck squamous cell carcinoma

Manli Zeng, Fen Li, Lei Wang, Chen Chen, Xiaolin Huang, Xingyu Wu, Wensheng She, Lin Zhou, Zezhang Tao
Pages: 3226-3232
Published online on: 20 December 2017

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Article

Inhibition of enhancer of zeste homolog 2 increases the expression of p16 and suppresses the proliferation and migration of ovarian carcinoma cells in vitro and in vivo

Fangfang Lu, Hong Xu, Qi Wang, Meiyi Li, Jiahua Meng, Yan Kuang
Pages: 3233-3239
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Article

TH588, an MTH1 inhibitor, enhances phenethyl isothiocyanate‑induced growth inhibition in pancreatic cancer cells

Fumiyoshi Ikejiri, Yoshio Honma, Takashi Kasukabe, Takeshi Urano, Junji Suzumiya
Pages: 3240-3244
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Article

Increased expression of monoamine oxidase A is associated with epithelial to mesenchymal transition and clinicopathological features in non-small cell lung cancer

Fei Liu, Liang Hu, Yuefan Ma, Bingyu Huang, Zihan Xiu, Peihua Zhang, Keyuan Zhou, Xudong Tang
Pages: 3245-3251
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Article

Potential anticancer effect of prostratin through SIK3 inhibition

Dalal Alotaibi, Suneetha Amara, Terrance L. Johnson, Venkataswarup Tiriveedhi
Pages: 3252-3258
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Article

Bergamottin, a natural furanocoumarin abundantly present in grapefruit juice, suppresses the invasiveness of human glioma cells via inactivation of Rac1 signaling

Wenzheng Luo, Zhenyu Song, Hongwei Sun, Junxin Liang, Shanshan Zhao
Pages: 3259-3266
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Article

Common module analysis reveals prospective targets and mechanisms of pediatric adrenocortical adenoma and carcinoma

Anurag Kulshrestha, Shikha Suman
Pages: 3267-3272
Published online on: 19 December 2017

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Article

Serum microRNA-193b as a promising biomarker for prediction of chemoradiation sensitivity in esophageal squamous cell carcinoma patients

Chung Man Chan, Kenneth K. Y. Lai, Enders K. O. Ng, Mei Na Kiang, Tiffany W. H. Kwok, Hector K. Wang, Kwok Wah Chan, Tsz Ting Law, Daniel K. Tong, Kin Tak Chan, Nikki P. Lee, Simon Law
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Article

MMP‑2 silencing reduces the osteogenic transformation of fibroblasts by inhibiting the activation of the BMP/Smad pathway in ankylosing spondylitis

Bo Yuan, Zhiming Wu
Pages: 3281-3286
Published online on: 29 December 2017

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Article

Methylation of DACT2 contributes to the progression of breast cancer through activating WNT signaling pathway

Li Guo, Xiaohong Wang, Yuguang Yang, Hongchun Xu, Zhihong Zhang, Lili Yin, Yan Wang, Maopeng Yang, Shu Zhao, Shuping Bai, Ling Zhao, Zhipeng Wang, Xin Lian, Ying Liu, Qingyuan Zhang
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Article

Detection of EGFR and BRAF mutations by competitive allele-specific TaqMan polymerase chain reaction in lung adenocarcinoma

Yang Yang, Yi Meng, Hang Zhang, Xiaoyan Shen, Rutian Li, Lixia Yu, Baorui Liu, Lifeng Wang
Pages: 3295-3304
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Article

miR‑433 accelerates acquired chemoresistance of gallbladder cancer cells by targeting cyclin M

Jianhua Yu, Weiguang Zhang, Baochun Lu, Hongwei Qian, Haijun Tang, Zhiyang Zhu, Xinggui Yuan, Peitu Ren
Pages: 3305-3312
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Article

Effects of thalidomide on growth and VEGF-A expression in SW480 colon cancer cells

Xin Zhang, Hesheng Luo
Pages: 3313-3320
Published online on: 19 December 2017

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Article

Over-activated PD-1/PD-L1 axis facilitates the chemoresistance of diffuse large B-cell lymphoma cells to the CHOP regimen

Juan Liu, Lina Quan, Chunhui Zhang, Aichun Liu, Dongxia Tong, Jinghua Wang
Pages: 3321-3328
Published online on: 21 December 2017

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Case Report

BRCA1 homozygous unclassified variant in a patient with non‑Fanconi anemia: A case report Erratum in /10.3892/ol.2018.9015

Bondavalli Davide, Malvestiti Francesca, Pensotti Valeria, Feroce Irene, Bonanni Bernardo
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Article

STAT3 promotes the proliferation and migration of hepatocellular carcinoma cells by regulating AKT2

Yi Xie, Jianmin Li, Chao Zhang
Pages: 3333-3338
Published online on: 21 December 2017

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Article

Clinical value of the preoperative neutrophil-to-lymphocyte ratio and red blood cell distribution width in patients with colorectal carcinoma

Fuyan Han, Xuming Shang, Furong Wan, Zhanfeng Liu, Wenjun Tian, Dan Wang, Yiqing Liu, Yong Wang, Bingchang Zhang, Ying Ju
Pages: 3339-3349
Published online on: 27 December 2017

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Article

Gene expression analyses associated with malignant phenotypes of metastatic sub-clones derived from a mouse oral squamous cell carcinoma Sq-1979 cell line

Mitsutaka Adachi, Masako Mizuno‑Kamiya, Eiji Takayama, Harumi Kawaki, Toshihiro Inagaki, Shigeki Sumi, Masayuki Motohashi, Yasunori Muramatsu, Shin‑Ichiro Sumitomo, Michio Shikimori, Yutaka Yamazaki, Nobuo Kondoh
Pages: 3350-3356
Published online on: 19 December 2017

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Article

MiR-34c induces apoptosis and inhibits the viability of M4e cells by targeting BCL2

Rui Li, Hongxia Zhang, Xiling Zheng
Pages: 3357-3361
Published online on: 19 December 2017

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Article

A novel approach to glioma therapy using an oncolytic adenovirus with two specific promoters

Feng Liu, Kaya Xu, Hua Yang, Yuming Li, Jian Liu, Jixiang Wang, Zhizhong Guan
Pages: 3362-3368
Published online on: 21 December 2017

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Article

Long non-coding RNA CCAT2 promotes epithelial-mesenchymal transition involving Wnt/β-catenin pathway in epithelial ovarian carcinoma cells

Beidi Wang, Meimei Liu, Rujin Zhuang, Jing Jiang, Jiayin Gao, Hao Wang, He Chen, Zongfeng Zhang, Ye Kuang, Peiling Li
Pages: 3369-3375
Published online on: 20 December 2017

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Article

Escitalopram oxalate inhibits proliferation and migration and induces apoptosis in non-small cell lung cancer cells

I Yuan, Chi‑Ting Horng, Vincent Chin‑Hung Chen, Chun‑Hung Chen, Li‑Jeng Chen, Tsai‑Ching Hsu, Bor‑Show Tzang
Pages: 3376-3382
Published online on: 21 December 2017

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Article

Blood supply characteristics of pedunculated hepatocellular carcinoma prior to and following transcatheter arterial chemoembolization treatment: An angiographic demonstration

Dexiao Huang, Yong Chen, Qingle Zeng, Jianbo Zhao, Xizhong Wu, Renhua Wu, Yanhao Li
Pages: 3383-3389
Published online on: 21 December 2017

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Review Open Access

Therapeutic targeting of noncoding RNAs in hepatocellular carcinoma: Recent progress and future prospects (Review)

Zhangang Xiao, Jing Shen, Lin Zhang, Mingxing Li, Wei Hu, Chihin Cho
Pages: 3395-3402
Published online on: 09 January 2018

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Review

Discoidin domain receptor 1: New star in cancer-targeted therapy and its complex role in breast carcinoma (Review)

Hui Jing, Jingyuan Song, Junnian Zheng
Pages: 3403-3408
Published online on: 15 January 2018

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Review

Molecular background of the regional lymph node metastasis of gastric cancer (Review)

Tong Zhu, Xueqian Hu, Pinkang Wei, Guangzhi Shan
Pages: 3409-3414
Published online on: 16 January 2018

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Review Open Access

Notch signaling and non-small cell lung cancer (Review)

Bin Zou, Xue‑Liang Zhou, Song‑Qing Lai, Ji‑Chun Liu
Pages: 3415-3421
Published online on: 08 January 2018

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Article Open Access

Combined treatment with D-allose, docetaxel and radiation inhibits the tumor growth in an in vivo model of head and neck cancer

Hiroshi Hoshikawa, Kazuyo Kamitori, Kanako Indo, Terushige Mori, Mizuna Kamata, Tomoko Takahashi, Masaaki Tokuda
Pages: 3422-3428
Published online on: 12 January 2018

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Article Open Access

Low-molecular-weight polysaccharides from Agaricus blazei Murrill modulate the Th1 response in cancer immunity

Liyan Jiang, Zhipu Yu, Yu Lin, Liran Cui, Shujuan Yao, Liyan Lv, Jicheng Liu
Pages: 3429-3436
Published online on: 15 January 2018

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Article Open Access

Angiogenesis for tumor vascular normalization of Endostar on hepatoma 22 tumor-bearing mice is involved in the immune response

Qingyu Xu, Junfei Gu, You Lv, Jiarui Yuan, Nan Yang, Juan Chen, Chunfei Wang, Xuefeng Hou, Xiaobin Jia, Liang Feng, Guowen Yin
Pages: 3437-3446
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Article Open Access

Expression and clinical significance of serum MMP‑7 and PTEN levels in patients with acute myeloid leukemia

Jiang Wu, Yu Song
Pages: 3447-3452
Published online on: 15 January 2018

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Article Open Access

Evaluation of therapeutic effects of 125I particles brachytherapy for recurrent bladder cancer

Yu-Ming Zhou, Xiao Feng, Bing-Cheng Zhou, Yue-Feng Fan, Yuan-Liang Huang
Pages: 3453-3457
Published online on: 29 December 2017

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Article Open Access

Fucosterol exhibits selective antitumor anticancer activity against HeLa human cervical cell line by inducing mitochondrial mediated apoptosis, cell cycle migration inhibition and downregulation of m-TOR/PI3K/Akt signalling pathway Retraction in /10.3892/ol.2022.13618

Hongye Jiang, Jie Li, Aiyue Chen, Yinguang Li, Meng Xia, Peng Guo, Shuzhong Yao, Shuqin Chen
Pages: 3458-3463
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Article Open Access

miR-96 promotes breast cancer metastasis by suppressing MTSS1

Wei Xie, Feng Sun, Lin Chen, Xinjian Cao
Pages: 3464-3471
Published online on: 04 January 2018

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Article Open Access

Role of epithelial-mesenchymal transition markers E-cadherin, N-cadherin, β-catenin and ZEB2 in laryngeal squamous cell carcinoma

Guang‑Jie Zhu, Pan‑Pan Song, Han Zhou, Xiao‑Hui Shen, Jun‑Guo Wang, Xiao‑Feng Ma, Ya‑Jun Gu, Ding‑Ding Liu, An‑Ning Feng, Xiao‑Yun Qian, Xia Gao
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Article Open Access

HIF-1α promotes ZEB1 expression and EMT in a human bladder cancer lung metastasis animal model Corrigendum in /10.3892/ol.2021.12860

Jianning Zhu, Zhixin Huang, Mengzhao Zhang, Weiyi Wang, Hua Liang, Jin Zeng, Kaijie Wu, Xinyang Wang, Jer‑Tsong Hsieh, Peng Guo, Jinhai Fan
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Long noncoding RNA BLACAT1 promotes cell proliferation and invasion in human cervical cancer

Dan Shan, Yumin Shang, Tongxiu Hu
Pages: 3490-3495
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Article Open Access

Abnormal expression of circulating and tumor-infiltrating carcinoembryonic antigen-related cell adhesion molecule 1 in patients with glioma

Jinhu Li, Xiaodong Liu, Yijun Duan, Hongqin Wang, Wen Su, Yazhou Wang, Guotao Zhuang, Yimin Fan
Pages: 3496-3503
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Case Report Open Access

Primary non-Hodgkin's lymphoma of the vagina: A case report

Feng Wang, Xuquan Jing, Bo Liu, Xue Meng, Xindong Sun, Yongsheng Gao, Linlin Wang, Zheng Fu
Pages: 3504-3507
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Article Open Access

Short-term outcomes of reconstruction subsequent to intercalary resection of femoral diaphyseal metastatic tumor with pathological fracture: Comparison between segmental allograft and intercalary prosthesis

Deng‑Xing Lun, Yong‑Cheng Hu, Xiong‑Gang Yang, Feng Wang, Zhao‑Wan Xu
Pages: 3508-3517
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Application of deep learning to the classification of images from colposcopy

Masakazu Sato, Koji Horie, Aki Hara, Yuichiro Miyamoto, Kazuko Kurihara, Kensuke Tomio, Harushige Yokota
Pages: 3518-3523
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Association of histone deacetylase expression with histology and prognosis of ovarian cancer

Mitsutake Yano, Masanori Yasuda, Mika Sakaki, Koji Nagata, Takashi Fujino, Eiichi Arai, Takahiro Hasebe, Masaki Miyazawa, Mariko Miyazawa, Naoki Ogane, Kosei Hasegawa, Hisashi Narahara
Pages: 3524-3531
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Article Open Access

Differential microRNA expression profiles in tamoxifen-resistant human breast cancer cell lines induced by two methods

Peng Ye, Cheng Fang, Hui Zeng, Yu Shi, Zhongya Pan, Nairui An, Keli He, Li Zhang, Xinghua Long
Pages: 3532-3539
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Utility of Survivin, BAP1, and Ki‑67 immunohistochemistry in distinguishing epithelioid mesothelioma from reactive mesothelial hyperplasia

Kei Kushitani, Vishwa Jeet Amatya, Amany Sayed Mawas, Rui Suzuki, Yoshihiro Miyata, Morihito Okada, Kouki Inai, Takumi Kishimoto, Yukio Takeshima
Pages: 3540-3547
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Effects of NOB1 on the pathogenesis of osteosarcoma and its expression on the chemosensitivity to cisplatin

Leiming Luo, Yuanhui Wang, Yiran Yin, Jianhua Ge, Xiaobo Lu
Pages: 3548-3551
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Potential prognostic biomarkers identified by DNA methylation profiling analysis for patients with lung adenocarcinoma

Liankui Han, Gang Xu, Chuan Xu, Bo Liu, Di Liu
Pages: 3552-3557
Published online on: 12 January 2018

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Comparison of the safety of the application of painless gastroscopy and ordinary gastroscopy in chronic hypertension patients combined with early gastric cancer

Fangli Men, Lianmin Wei, Bing Liu, Fengting Wu, Jingyu Liu, Ni Guo, Qing Niu
Pages: 3558-3561
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Rapid detection of quantum dot immune chromatography nasopharyngeal carcinoma EBNA1 antibody

Jian He, Jing Xu, Ping Wu, Lingfeng Liao, Huatao Quan, Jing Kang, Yongquan Tian, Yaoyun Tang
Pages: 3562-3565
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Article Open Access

Risk factors and coping strategies of severe community-acquired pneumonia in chemotherapy induction period of acute leukemia

Ning Li, Qingcheng Duan, Weidan Zhang
Pages: 3566-3571
Published online on: 04 January 2018

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Article Open Access

Parthenolide facilitates apoptosis and reverses drug-resistance of human gastric carcinoma cells by inhibiting the STAT3 signaling pathway

Hua Li, Hang Lu, Meng Lv, Qingsheng Wang, Yuping Sun
Pages: 3572-3579
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Article Open Access

Values of miR-34a and miR-218 expression in the diagnosis of cervical cancer and the prediction of prognosis

Ping Wang, Guanyun Zhai, Yunyan Bai
Pages: 3580-3585
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Loss of CDX2 gene expression is associated with DNA repair proteins and is a crucial member of the Wnt signaling pathway in liver metastasis of colorectal cancer

Csaba Tóth, Farkas Sükösd, Erzsébet Valicsek, Esther Herpel, Peter Schirmacher, László Tiszlavicz
Pages: 3586-3593
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Article Open Access

The role of immune cell subpopulations in the growth and rejection of TC‑1/A9 tumors in novel mouse strains differing in the H2‑D haplotype and NKC domain

Marie Indrová, Joanna Rossowska, Elzbieta Pajtasz‑Piasecka, Romana Mikyšková, Jan Richter, Jozef Rosina, Radislav Sedlacek, Anna Fišerová
Pages: 3594-3601
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Article Open Access

Diffuse large B-cell lymphoma: 10 years' real-world clinical experience with rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisolone

Matej Horvat, Vesna Zadnik, Tanja Južnič Šetina, Lučka Boltežar, Jana Pahole Goličnik, Srdjan Novaković, Barbara Jezeršek Novaković
Pages: 3602-3609
Published online on: 11 January 2018

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Article Open Access

Primary pulmonary intravascular large B-cell lymphoma: A report of three cases and literature review

Yingwei Zhang, Lintao Bi, Yuying Qiu, Tingting Zhao, Mengshu Cao, Jingjing Ding, Fanqing Meng, Hourong Cai
Pages: 3610-3613
Published online on: 09 January 2018

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Article Open Access

Expression of matrix metalloproteinase-7 correlates with the invasion of T1 colorectal carcinoma

Fumihiko Urushibara, Eisuke Shiozawa, Hideyuki Miyachi, Masashi Misawa, Tomonari Cho, Yusuke Takehara, Nana Arai, Toshitaka Funaki, Sakiko Tazawa, Mayumi Homma, Tomoko Norose, Mutsuko Omatsu, Toshiko Yamochi, Toshiaki Kunimura, Genshu Tate, Kazuho Honda, Ishida Fumio, Shin‑Ei Kudo, Masafumi Takimoto
Pages: 3614-3620
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Article Open Access

Effects of Yangzheng Sanjie Decoction-containing serum mediated by microRNA-7 on cell proliferation and apoptosis in gastric cancer

Wanqun Chen, Yaya Yu, Naikun Yang, Jingli Zhu, Ke Li, Ruocun Li, Wenqiao Su, Lina Luo, Ling Hu, Gengxin Chen, Haixia Deng
Pages: 3621-3629
Published online on: 09 January 2018

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Article Open Access

The regulation and function of microRNA-377/RASSF8 signaling axis in gastric cancer

Xiaobo Bo, Yusheng Chen, Weizhong Sheng, Yuda Gong, Haiyu Wang, Weidong Gao, Bo Zhang
Pages: 3630-3638
Published online on: 08 January 2018

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Article Open Access

Ηypoxia-inducible factor 1-α promotes colon cell proliferation and migration by upregulating AMPK-related protein kinase 5 under hypoxic conditions

Ji Kui Peng, Shi Qiang Shen, Ju Wang, Hong Wei Jiang, Yong Qiang Wang
Pages: 3639-3645
Published online on: 08 January 2018

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Article Open Access

Paclitaxel plus nedaplatin vs. paclitaxel plus carboplatin in women with epithelial ovarian cancer: A multi-center, randomized, open-label, phase III trial

Li Li, Qingqing Zhuang, Zeyi Cao, Rutie Yin, Yaping Zhu, Lirong Zhu, Xing Xie, Youzhong Zhang, Qiang Wu, Jianhua Zheng, Qi Zhou, Xiaoping Li, Lingying Wu, Youji Feng, Changyu Wang
Pages: 3646-3652
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Article Open Access

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Xia Lin, Yingming Xiang, Hongcan Shi, Fangbiao Zhang
Pages: 3653-3661
Published online on: 15 January 2018

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Article Open Access

Analysis of middle- and long-term efficacy of thoracoscope-assisted segmental resection of the lung on non-small cell lung cancer in the early stage

Ning Ding, Ning Zhou, Qinglin Li, Guangming Ren, Min Zhou
Pages: 3662-3668
Published online on: 12 January 2018

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Article Open Access

Two protein-coding genes act as a novel clinical signature to predict prognosis in patients with ovarian serous cystadenocarcinoma

Jue Zhang, Meng Xu, Han Gao, Jin‑Chen Guo, Yu‑Lin Guo, Miao Zou, Xu‑Feng Wu
Pages: 3669-3675
Published online on: 12 January 2018

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Article Open Access

Role and underlying mechanism of SPATA12 in oxidative damage

Daobing Wu, Dan Li, Zhiyong Liu, Xiaowen Liu, Shihua Zhou, Hongyan Duan
Pages: 3676-3684
Published online on: 08 January 2018

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Article Open Access

Characteristics of breast metastases from non-breast solid tumors in 22 patients from a southern Chinese population

Peng Sun, Jiewei Chen, Jiabin Lu, Rongzhen Luo, Mei Li, Jiehua He
Pages: 3685-3693
Published online on: 08 January 2018

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Article Open Access

Fbxw7 regulates renal cell carcinoma migration and invasion via suppression of the epithelial-mesenchymal transition

Hongchao He, Jun Dai, Zhaoping Xu, Wei He, Xiaojing Wang, Yu Zhu, Haofei Wang
Pages: 3694-3702
Published online on: 08 January 2018

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Article Open Access

Serum immunoglobulin E response as a marker for unfavorable prognosis following cholesteryl pullulan-MAGE A4 vaccination

Takehiro Abiko, Takahiro Tsuchikawa, Kengo Miyauchi, Masataka Wada, Noriaki Kyogoku, Toshiaki Shichinohe, Yoshihiro Miyahara, Shinichi Kageyama, Hiroaki Ikeda, Hiroshi Shiku, Satoshi Hirano
Pages: 3703-3711
Published online on: 10 January 2018

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Article Open Access

Homeobox B3 promotes tumor cell proliferation and invasion in glioblastoma

Ke Xu, Chun Qiu, Hua Pei, Muhammad Aamer Mehmood, Huamin Wang, Liang Li, Qianfeng Xia
Pages: 3712-3718
Published online on: 08 January 2018

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Article Open Access

Downregulation of ribonucleotide reductase subunits M2 induces apoptosis and G1 arrest of cervical cancer cells

Nan Wang, Yong Li, Jianhong Zhou
Pages: 3719-3725
Published online on: 16 January 2018

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Article Open Access

Sequencing of circulating tumor DNA for dynamic monitoring of gene mutations in advanced non-small cell lung cancer

Ruilian Xu, Guolin Zhong, Tanxiao Huang, Wan He, Cheng Kong, Xiaoni Zhang, Ying Wang, Ming Liu, Mingyan Xu, Shifu Chen
Pages: 3726-3734
Published online on: 16 January 2018

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Article Open Access

Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer

Yi Li, Ji Wang, Li Tan, Beina Hui, Xiaowei Ma, Yanli Yan, Chaofan Xue, Xiaoting Shi, Emmanuel Kwateng Drokow, Juan Ren
Pages: 3735-3745
Published online on: 04 January 2018

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Article Open Access

Prognostic analysis of hepatocellular carcinoma on the background of liver cirrhosis via contrast-enhanced ultrasound and pathology

Yukai He, Fenghua Liu, Shaofeng Mou, Qingyan Li, Sikui Wang
Pages: 3746-3752
Published online on: 12 January 2018

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Article Open Access

Transcription factor PU.1 is involved in the progression of glioma

Yuanzhi Xu, Song Gu, Yunke Bi, Xiangqian Qi, Yujin Yan, Meiqing Lou
Pages: 3753-3759
Published online on: 10 January 2018

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Article

IFN-γ induces the upregulation of RFXAP via inhibition of miR-212-3p in pancreatic cancer cells: A novel mechanism for IFN-γ response

Guoping Ding, Liangjing Zhou, Tao Shen, Liping Cao
Pages: 3760-3765
Published online on: 12 January 2018

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Article

XPA expression is a predictive marker of the effectiveness of neoadjuvant chemotherapy for locally advanced uterine cervical cancer

Takuma Wada, Takeshi Fukuda, Masahiro Shimomura, Yuta Inoue, Masaru Kawanishi, Reiko Tasaka, Tomoyo Yasui, Kazuo Ikeda, Toshiyuki Sumi
Pages: 3766-3771
Published online on: 16 January 2018

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Article

Association between receptor interacting serine/threonine kinase 2 polymorphisms and gastric cancer susceptibility

Masafumi Ota, Tomomitsu Tahara, Toshimi Otsuka, Wu Jing, Tomoe Nomura, Ranji Hayashi, Takeo Shimasaki, Masakatsu Nakamura, Tomoyuki Shibata, Tomiyasu Arisawa
Pages: 3772-3778
Published online on: 12 January 2018

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Article

Clinicopathological and functional implications of the inhibitor of apoptosis proteins survivin and XIAP in esophageal cancer

Levent Dizdar, Lisa M. Jünemann, Thomas A. Werner, Pablo E. Verde, Stephan E. Baldus, Nikolas H. Stoecklein, Wolfram T. Knoefel, Andreas Krieg
Pages: 3779-3789
Published online on: 09 January 2018

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Article

17β-estradiol regulates the malignancy of cancer stem-like cells derived from the MCF7 cell line partially through Sox2

Lian Guo, Feng Li, Mengyuan Wang, Yue Xu, Bangqiong Wang, Dongchuan Ran, Xianxiang Zhang
Pages: 3790-3795
Published online on: 15 January 2018

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Article

Prognostic significance of c-Met, β-catenin and FAK in patients with hepatocellular carcinoma following surgery

Xue‑Yi Gong, Ning Ma, Hong‑Xu Xu, Fan Chen, Xiao‑Hui Huang, Qian Wang
Pages: 3796-3805
Published online on: 05 January 2018

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Article

Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1

Xiupeng Zhang, Guiyang Jiang, Jingjing Wu, Haijing Zhou, Yong Zhang, Yuan Miao, Yangyang Feng, Juanhan Yu
Pages: 3806-3813
Published online on: 16 January 2018

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Article

Anticancer effect of miR-96 inhibitor in bladder cancer cell lines

Ting Xu, Xiao‑Wen Du, Jun‑Biao Hu, Yong‑Feng Zhu, Hui‑Ling Wu, Guo‑Ping Dai, Yao‑Min Shu, Jun Ouyang
Pages: 3814-3819
Published online on: 08 January 2018

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Article

TNF-α promotes colon cancer cell migration and invasion by upregulating TROP-2

Peng Zhao, Zhongtao Zhang
Pages: 3820-3827
Published online on: 05 January 2018

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Article

PIAS1 inhibited the metastasis of gastric cancer cell by epithelial-mesenchymal transition regulation within the inflammatory microenvironment

Xiaoyu Wang, Libing Wang, Yan Xu, Guohua Zhang, Yunlin Wu, Ping Chen
Pages: 3828-3837
Published online on: 16 January 2018

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Article

Overexpression of RHEB is associated with metastasis and poor prognosis in hepatocellular carcinoma

Fuchen Liu, Zeya Pan, Jinmin Zhang, Junsheng Ni, Chao Wang, Zhenguang Wang, Fangming Gu, Wei Dong, Weiping Zhou, Hui Liu
Pages: 3838-3845
Published online on: 10 January 2018

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Article

Ubiquitin-specific protease 15 promotes tumor cell invasion and proliferation in glioblastoma

Ke Xu, Hua Pei, Zhenhao Zhang, Huamin Wang, Liang Li, Qianfeng Xia
Pages: 3846-3851
Published online on: 08 January 2018

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Article

Remodeling and spacing factor 1 overexpression is associated with poor prognosis in renal cell carcinoma

Xiuwei Zhang, Dongwei Xue, Fengxia Hao, Lingling Xie, Jiani He, Junda Gai, Yuhui Liu, Hongtao Xu, Qingchang Li, Enhua Wang
Pages: 3852-3857
Published online on: 15 January 2018

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Article

Metadherin contributes to epithelial-mesenchymal transition and paclitaxel resistance induced by acidic extracellular pH in nasopharyngeal carcinoma

Changyun Yu, Yong Liu, Zhaobing Qin
Pages: 3858-3863
Published online on: 10 January 2018

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Article

Effect of selective inhibition of aquaporin 1 on chemotherapy sensitivity of J82 human bladder cancer cells

Xuefeng Zhang, Yun Chen, Liming Dong, Benkang Shi
Pages: 3864-3869
Published online on: 04 January 2018

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Article

Brucea javanica seed oil enhances the radiosensitivity of esophageal cancer by inhibiting hypoxia-inducible factor 1α, in vitro and in vivo

Peng Pan, Bai‑Xia Yang, Xiao‑Lin Ge
Pages: 3870-3875
Published online on: 12 January 2018

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Article

Distinctive profiles of tumor-infiltrating immune cells and association with intensity of infiltration in colorectal cancer

Yugang Wu, Lei Yuan, Qicheng Lu, Haiyan Xu, Xiaozhou He
Pages: 3876-3882
Published online on: 10 January 2018

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Article

HSPA12B overexpression induces cisplatin resistance in non-small-cell lung cancer by regulating the PI3K/Akt/NF-κB signaling pathway

Wei Chen, Xiaoqun Liu, Sujuan Yuan, Tiankui Qiao
Pages: 3883-3889
Published online on: 16 January 2018

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Case Report

Recurrence of adenoid cystic carcinoma of the trachea treated with radical radiotherapy: A case report

Konrad Pawlewicz, Zbigniew Szutkowski, Andrzej Kawecki
Pages: 3890-3894
Published online on: 12 January 2018

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Article

Etoposide radiosensitizes p53-defective cholangiocarcinoma cell lines independent of their G2 checkpoint efficacies

Arunee Hematulin, Sutiwan Meethang, Kitsana Utapom, Sopit Wongkham, Daniel Sagan
Pages: 3895-3903
Published online on: 09 January 2018

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Article

Effects of PHA-665752 and vemurafenib combination treatment on in vitro and murine xenograft growth of human colorectal cancer cells with BRAFV600E mutations

Jie Zhi, Zhongxin Li, Jian Lv, Bo Feng, Donghai Yang, Liang Xue, Zhaolong Zhao, Yanni Zhang, Jianhua Wu, Yingchao Jv, Yitao Jia
Pages: 3904-3910
Published online on: 10 January 2018

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Article

Human sodium iodide transporter gene-mediated imaging and therapy of mouse glioma, comparison between 188Re and 131I

Rui Guo, Yun Xi, Min Zhang, Ying Miao, Miao Zhang, Biao Li
Pages: 3911-3917
Published online on: 08 January 2018

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Article

An obligatory anaerobic Salmonella typhimurium strain redirects M2 macrophages to the M1 phenotype

Mei Yang, Juan Xu, Qi Wang, An‑Qin Zhang, Kun Wang
Pages: 3918-3922
Published online on: 08 January 2018

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Article

Overexpression of flavin-containing monooxygenase 5 predicts poor prognosis in patients with colorectal cancer

Tong Zhang, Ping Yang, Jianchang Wei, Wanglin Li, Junbin Zhong, Huacui Chen, Jie Cao
Pages: 3923-3927
Published online on: 04 January 2018

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Article

Flattening filter-free technique in volumetric modulated arc therapy for lung stereotactic body radiotherapy: A clinical comparison with the flattening filter technique

Shuri Aoki, Hideomi Yamashita, Akihiro Haga, Kanabu Nawa, Toshikazu Imae, Wataru Takahashi, Osamu Abe, Keiichi Nakagawa
Pages: 3928-3936
Published online on: 16 January 2018

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Article

miR302a inhibits the proliferation of esophageal cancer cells through the MAPK and PI3K/Akt signaling pathways

Daokui Xia, Shumei Tian, Zhen Chen, Wenchao Qin, Quan Liu
Pages: 3937-3943
Published online on: 12 January 2018

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Article

Induction of apoptosis in human cervical carcinoma HeLa cells by active compounds from Hypericum ascyron L.

Xiu‑Mei Li, Xue‑Gang Luo, Jun‑Fang He, Nan Wang, Hao Zhou, Pei‑Long Yang, Tong‑Cun Zhang
Pages: 3944-3950
Published online on: 16 January 2018

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Article

[18F]FDG-PET/CT and MRI for initial pelvic lymph node staging in patients with cervical carcinoma: The potential usefulness of [18F]FDG-PET/MRI

Philip Anner, Marius Mayerhöfer, Wolfgang Wadsak, Silvana Geleff, Robert Dudczak, Alexander Haug, Marcus Hacker, Georgios Karanikas
Pages: 3951-3956
Published online on: 12 January 2018

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Article

β-elemene enhances anticancer and anti-metastatic effects of osteosarcoma of ligustrazine in vitro and in vivo

Min Fang, Xiaolong Mei, Hui Yao, Tao Zhang, Na Lu, Yanshi Liu, Wenyue Xu, Chunyou Wan
Pages: 3957-3964
Published online on: 12 January 2018

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Article

Effect of TLR4 on the growth of SiHa human cervical cancer cells via the MyD88‑TRAF6-TAK1 and NF-κB-cyclin D1-STAT3 signaling pathways

Li Ma, Li Feng, Xiaoping Ding, Yongwang Li
Pages: 3965-3970
Published online on: 16 January 2018

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Article

TGFBR1*6A is a potential modifier of migration and invasion in colorectal cancer cells

Rui Zhou, Ying Huang, Boran Cheng, Yulei Wang, Bin Xiong
Pages: 3971-3976
Published online on: 04 January 2018

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Article

Long non-coding RNA SPRY4-IT1 promotes the proliferation and invasion of U251 cells through upregulation of SKA2

Xiao‑Jun He, Er‑Bao Bian, Chun‑Chun Ma, Chao Wang, Hong‑Liang Wang, Bing Zhao
Pages: 3977-3984
Published online on: 12 January 2018

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Article

IL-10 in the microenvironment of HNSCC inhibits the CpG ODN-induced IFN-α secretion of pDCs

Karl‑Ludwig Bruchhage, Sabrina Heinrichs, Barbara Wollenberg, Ralph Pries
Pages: 3985-3990
Published online on: 11 January 2018

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Article

Cardamonin enhances the anti-proliferative effect of cisplatin on ovarian cancer

Peiguang Niu, Daohua Shi, Shusheng Zhang, Yanting Zhu, Jintuo Zhou
Pages: 3991-3997
Published online on: 08 January 2018

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Article

MicroRNA-433 targets AKT3 and inhibits cell proliferation and viability in breast cancer

Xiaolei Hu, Jie Wang, Wan He, Pan Zhao, Changsheng Ye
Pages: 3998-4004
Published online on: 16 January 2018

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Article

Sp5 negatively regulates the proliferation of HCT116 cells by upregulating the transcription of p27

Masaya Miyamoto, Tomoatsu Hayashi, Yoshihiro Kawasaki, Tetsu Akiyama
Pages: 4005-4009
Published online on: 15 January 2018

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Article

Apoptosis-sensitizing activity of birinapant in head and neck squamous cell carcinoma cell lines

Roman C. Brands, Mario J.J. Scheurer, Stefan Hartmann, Axel Seher, Alexander C. Kübler, Urs D.A. Müller‑Richter
Pages: 4010-4016
Published online on: 12 January 2018

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Article

Predictive value of inflammatory indexes on the chemotherapeutic response in patients with unresectable lung cancer: A retrospective study

Haifeng Sun, Pingping Hu, Jiajun Du, Xinying Wang
Pages: 4017-4025
Published online on: 12 January 2018

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Article

Downregulation of the long non-coding RNA taurine-upregulated gene 1 inhibits glioma cell proliferation and invasion and promotes apoptosis

Zhijun Zhao, Bin Wang, Junhai Hao, Weitao Man, Yongkai Chang, Shunchang Ma, Yeshuai Hu, Fusheng Liu, Jun Yang
Pages: 4026-4032
Published online on: 12 January 2018

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Article

A retrospective study of pattern of recurrence after radical surgery for thoracic esophageal carcinoma with or without postoperative radiotherapy

Yichun Wang, Li Zhang, Dongmei Ye, Wanli Xia, Jun Jiang, Xiumei Wang, Mingxia Zhang, Fan Wang
Pages: 4033-4039
Published online on: 16 January 2018

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Retraction Open Access

[Retracted] Expression of miR-711 and mechanism of proliferation and apoptosis in human gastric carcinoma

Sheng‑Xing Zhu, Xian‑Zhou Tong, Shuijun Zhang
Pages: 4040-4040
Published online on: 05 January 2018

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Journal Cover
March-2026 Volume 31 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Immune microenvironment and treatment response of dMMR gastric cancer: Heterogeneity and implications for immunotherapy

Liping Wang, Xinliang Zhong, Mengxing Diao, Wei Deng
Article Number: 119
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑150 upregulation reduces osteosarcoma cell invasion and metastasis by downregulating Ezrin

Ce Zhan, Cheng Li, Hao Zhang, Hao Tang, Fang Ji, Su-Chi Qiao, Wei-Dong Xu, Zhi-Wei Wang
Article Number: 118
Published online on: 26 January 2026

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Article Open Access

Unveiling mitochondrial DNA copy number alterations: Insights into progression from cervical intraepithelial neoplasia to cervical cancer

İzzet Özgürlük, Haktan Bağış Erdem, Mustafa Tarık Alay, Okan Oktar, Firdevs Şahin-Duran, Ezgi Çevik‑Demir, Aysu Yeşim Tezcan, Hüseyin Levent Keskin
Article Number: 117
Published online on: 23 January 2026

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Case Report Open Access

Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report

Nobuhito Hara, Yumi Yoshii, Yoshiki Kojitani, Rika Sasaki, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Junichi Takemura, Ryo Miyata, Masatsugu Hamaji, Mitsuharu Hosono, Fumi Okada, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 116
Published online on: 22 January 2026

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Case Report Open Access

Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review

Danli Ye, Min Wu, Jiawen Zong, Weipeng Zeng, Guangning Yan, Juan Zhou, Wei Wang
Article Number: 115
Published online on: 20 January 2026

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Article Open Access

NDC80 kinetochore complex component is a potential molecular target of adenoid cystic carcinoma

Xia Yan, Sumei He, Yuansheng Lin, Jin Zhang, Jian Huan, Haibo Chen, Lina Lu
Article Number: 114
Published online on: 20 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑429 inhibits gastric cancer migration and invasion through the downregulation of specificity protein 1

Jingbin Ni, Yisha Yang, Di Liu, Hui Sun, Shimao Jin, Jingying Li
Article Number: 113
Published online on: 19 January 2026

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Review Open Access

Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome (Review)

Hanyue Ying, Ke Zhang, Yu Chen, Qinghua Deng, Chun Mao, Jiawei Li
Article Number: 112
Published online on: 19 January 2026

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Article Open Access

Endostar combined with docetaxel or cisplatin in the management of malignant ascites through hyperthermic intraperitoneal chemotherapy: A retrospective cohort study

Jing Wu, Dashan Yin, Jin Qian, Yi Zhou, Yajun Wu, Ganlu Zhang
Article Number: 111
Published online on: 14 January 2026

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Review

 Three‑dimensional culture of tumor cells (Review)

Shiyao Du, Jinyu Yang, Hui Li, Shanshan Men, Dongping Xu, Haifeng Wang
Article Number: 110
Published online on: 15 January 2026

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Article Open Access

Cytotoxic, apoptotic and genotoxic effects of thymoquinone‑oxime derivative on gastric cancer cells: An in vitro study

Kübra Bozali̇, Zeynep İnce, Nurhi̇lal Kiziltoprak, Taygun Gülşen, Mehmet Köstek, Yasi̇r Musa Kesgi̇n, Muhammer Ergenç, Mi̇ne Dağgez, Eren Altun, Fati̇h Taşkesen, Cebrai̇l Akyüz, Oğuzhan Sunamak, Mustafa Duman, Eray Meti̇n Güler
Article Number: 109
Published online on: 14 January 2026

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Review Open Access

Tumor microenvironment in gastric cancer immune tolerance and its therapeutic relevance in immunomodulation (Review)

Zihe Guan, Lichao Han, Baojiang Chen, Yijia Ma, Qianyue Ni, Zijian Wang, Jingyu Yang, Zheng Liu
Article Number: 108
Published online on: 13 January 2026

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Article Open Access

Phosphorylated‑EGFR and MMP7 upregulation in gastric cancer: Association with metastasis and poor prognosis

Biran Ding, Yiqiu Wan, Yao Wu, Zhan Zhang, Ying Ma, Zuo Wang, Runqiu Jiang, Tao Li
Article Number: 107
Published online on: 14 January 2026

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Article Open Access

Study on the expression level of folate receptor γ in thyroid cancer and its association with clinicopathological characteristics

Jinying Cao, Yanxu Li, Xin Deng, Bo Lv, Ling Han, Ling Tong
Article Number: 106
Published online on: 12 January 2026

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Article Open Access

Prognostic value of glioma‑associated oncogene homolog 1 and SET domain‑containing protein 2 immunohistochemical scores in locally advanced cervical cancer

Erick De La Cruz‑Hernández, Gabriela Carolina Morales‑Sandoval, Marcela Lizano, Alejandro Avilés‑Salas, Leonardo Josué Castro‑Muñoz, Adela Carrillo‑García, Maria Del Pilar Ramos‑Godinez, Jaime Alberto Coronel‑Martinez, Adriana Contreras‑Paredes
Article Number: 105
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Clinical significance of bromodomain‑containing protein 7 and its association with tumor progression in prostate cancer

Yong Liang, Baiping Dong, Jiangwei Shen, Caosheng Ma, Zhongping Ma
Article Number: 104
Published online on: 12 January 2026

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Article Open Access

LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance

Cairong Zhang, Jie Ma, Wenling Wang, Min Guo, Cuiliu Han, Madinamu Sadike, Kaichun Zhu
Article Number: 103
Published online on: 12 January 2026

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Article Open Access

Circular RNA hsa_circ_0006168: A potential biomarker for the diagnosis and prognosis of prostate cancer

Ye Ding, Mao-Tong Liu, Na Yu, Liusijie Gao, Li-Ping Chen
Article Number: 102
Published online on: 09 January 2026

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Article Open Access

Meta‑analysis of the clinical efficacy of anti‑PD‑1/L1 + paclitaxel/albumin‑paclitaxel + platinum vs. paclitaxel/albumin‑paclitaxel + platinum in the treatment of patients with advanced non‑small cell lung cancer

Feng Li, Suyun Yan, Liping Liu
Article Number: 101
Published online on: 09 January 2026

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Review Open Access

Progress in perioperative immunotherapy for lung cancer and analysis of therapy (Review)

Xiao Ma, Gaofeng Li, Heng Li, Lanjun Li, Hanting Zhao, Zhiqing Liu
Article Number: 100
Published online on: 09 January 2026

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Correction Open Access

[Corrigendum] p53 positively regulates the expression of cancer stem cell marker CD133 in HCT116 colon cancer cells

Xia Chen, Hua Guan, Xiao-Dan Liu, Da-Fei Xie, Yu Wang, Teng Ma, Bo Huang, Ping-Kun Zhou
Article Number: 99
Published online on: 08 January 2026

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Case Report Open Access

High‑intensity focused ultrasound in the multimodal treatment of colorectal cancer liver metastases: A case report

Yuanhong Yang, Hao Zhang, Yifan Shen, Fan Yang, Dan Zhao, Yujie Lin, Guohua Huang
Article Number: 98
Published online on: 07 January 2026

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Article Open Access

Exosomal microRNA‑448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis

Yuankun Chen, Tiantian Zhu, Fang Chen, Mingyue Niu, Haifeng Wu, Qiuping Wu, Zheng Wang, Wenting Li
Article Number: 97
Published online on: 07 January 2026

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Article

Diagnostic value of magnetic resonance imaging in preoperative evaluation of cervical cancer and analysis of pathological features

Xiaofei Cai, Xinjian Lu, Jinjun Yang, Xinxue Wei, Wenjing Yue, Yunqing Ban
Article Number: 96
Published online on: 07 January 2026

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Retraction Open Access

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk‑ChA‑1 and Mz‑ChA‑1 cell growth by inducing caspase‑dependent apoptosis and downregulation of survivin and Bcl‑2 expression

Fei Zhong, Jing Yang, Zhu-Ting Tong, Liu-Liu Chen, Lu-Lu Fan, Fang Wang, Xia-Li Zha, Jun Li
Article Number: 95
Published online on: 07 January 2026

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Article Open Access

Prognosis of liver transplantation and hepatectomy in patients with hepatocellular carcinoma meeting the Milan criteria: A systematic review and meta‑analysis

Jiling Wang, Zheng Pan, Yongzheng Wang, Yanshuo Ye, Wei Li
Article Number: 94
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Advances in targeting vasculogenic mimicry in malignant tumors using monomeric compounds from Traditional Chinese Medicine (Review)

Fang-Yuan Liu, Yu-Qian Fu, Dan-Ni Ding, Shao-Xuan Liu, Yu-Xin Zhao, Ying Shen
Article Number: 126
Published online on: 03 February 2026

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Article Open Access

Preoperative lymphocyte‑albumin‑monocyte index as an inflammation‑ and nutrition‑based predictor of overall survival in triple‑negative breast cancer: A retrospective cohort study

Boxiang Zhang, Kuan Wang, Maihemuti Aishanjiang, Fang Lan, Binlin Ma
Article Number: 125
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated

Yakui Mu, Na Sa, Liang Yu, Sumei Lu, Haibo Wang, Wei Xu
Article Number: 124
Published online on: 02 February 2026

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Review Open Access

Combination of extracellular vesicles and organoids as a prospective model for cancer research (Review)

Jia Cao, Yanan Xu, Yuhan Gao, Xing Li, Libin Wang
Article Number: 123
Published online on: 30 January 2026

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Case Report Open Access

Malignant adenomyoepithelioma with HRAS G13R mutation: A case report

Hiroko Kuwabara, Reika Takeda, Yoshitaka Utsumi, Toshitaka Nagao, Kosei Kimura, Yoshinobu Hirose, Mitsuhiko Iwamoto
Article Number: 122
Published online on: 30 January 2026

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Case Report Open Access

Recurrent microsatellite instability‑high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report

Tomoki Nakagawa, Naohiro Aruga, Hajime Watanabe, Ryota Masuda, Shunsuke Yamada, Masayuki Iwazaki
Article Number: 121
Published online on: 29 January 2026

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Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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