Recurrence of adenoid cystic carcinoma of the trachea treated with radical radiotherapy: A case report

Pawlewicz,Konrad; Szutkowski,Zbigniew; Kawecki,Andrzej

doi:10.3892/ol.2018.7780

March-2018 Volume 15 Issue 3

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March-2018 Volume 15 Issue 3

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Case Report

Recurrence of adenoid cystic carcinoma of the trachea treated with radical radiotherapy: A case report

Authors:
- Konrad Pawlewicz
- Zbigniew Szutkowski
- Andrzej Kawecki
View Affiliations / Copyright

Affiliations: Department of Radiotherapy, The Maria Skłodowska Curie Memorial Cancer Centre and Institute of Oncology, Warsaw 02‑781, Poland
Pages: 3890-3894
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Published online on: January 12, 2018

https://doi.org/10.3892/ol.2018.7780
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Abstract

Adenoid cystic carcinoma (ACC) of the trachea is a relatively rare tumor among thoracic diseases. The present study reports the case of a 23-year-old woman with ACC of the trachea who underwent surgical resection of the tumor in The National Institute of Tuberculosis and Lung Diseases (Warsaw, Poland). Histopathological examination revealed that the tumor was not completely resected (R2 resection) and strict observation of the patient was therefore prescribed. After ~9 years of follow‑up, clinical and histopathological tumor progression was confirmed and the patient was referred to the Centre of Oncology in Warsaw. The localization and advanced nature of the disease precluded surgical intervention, and radical radiotherapy was therefore performed using intensity‑modulated radiation therapy. A total dose of 7,590 Gy, the planning target volume, was administered. A hyperfractionation scheme of radiotherapy was used: 2 fractions of 1.15 Gy daily, with at least a 6 h break in between. Tumor regression was observed following treatment and has been maintained for >3 years, assessed by clinical and computed tomography and positron emission tomography imaging examinations.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Recurrence of adenoid cystic carcinoma of the trachea treated with radical radiotherapy: A case report

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