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Article Open Access

Analysis of middle- and long-term efficacy of thoracoscope-assisted segmental resection of the lung on non-small cell lung cancer in the early stage

  • Authors:
    • Ning Ding
    • Ning Zhou
    • Qinglin Li
    • Guangming Ren
    • Min Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Respiratory Medicine, The Affiliated Xuzhou City Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, P.R. China
    Copyright: © Ding et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3662-3668
    |
    Published online on: January 12, 2018
       https://doi.org/10.3892/ol.2018.7789
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Abstract

We investigated the short- and long-term efficacy of thoracoscope-assisted segmental resection of lung of non-small cell lung cancer (NSCLC). We selected a total of 94 patients with lung cancer in the early stage who were admitted to The First People's Hospital of Xuzhou for treatment between March 2011 and February 2012. Patients were divided randomly into either the control group (n=47) or the observation group (n=47). In the observation group, patients received thoracoscope-assisted segmental resection of lung, while in the control group, the conventional thoracic surgery was performed for treatment. After surgeries, we observed the incidence rate of complications among the two groups, and enzyme-linked immunosorbent assay (ELISA) was adopted to detect levels of inflammatory factors. We also compared the cardiac and pulmonary functions, the levels of immunoglobulins and subgroups of T lymphocytes in the peripheral blood of the patients. In addition, all patients attended a 5-year follow‑up to determine the recurrence and survival rate. Compared to the control group, patients in the observation group had significantly less intra-operative bleeding volume, a shorter duration of surgery, and suffered slighter pain after surgery (P<0.05). After surgery, the incidence rate of complications in the observation group was significantly lower than that in the control group (P<0.05). After surgeries, patients in both groups experienced a remarkable improvement in cardiac and pulmonary functions, and the improvement in the observation group was superior to that of the control group (P<0.05). During the 5-year follow-up, the survival rate of the observation group is significantly higher than that in thecontrol group, and patients in the observation group experienced a lower recurrence rate than those in the control group (P<0.05). Thus, thoracoscope-assisted segmental resection of lung is of great significance in clinical practice.
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1 

Borghaei H, Paz-Ares L, Horn L, Spigel DR, Steins M, Ready NE, Chow LQ, Vokes EE, Felip E, Holgado E, et al: Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N Engl J Med. 373:1627–1639. 2015. View Article : Google Scholar : PubMed/NCBI

2 

D'Addario G, Früh M, Reck M, Baumann P, Klepetko W and Felip E: ESMO Guidelines Working Group: Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 21 Suppl 5:v116–v119. 2010. View Article : Google Scholar : PubMed/NCBI

3 

Garon EB, Rizvi NA, Hui R, Leighl N, Balmanoukian AS, Eder JP, Patnaik A, Aggarwal C, Gubens M, Horn L, et al: KEYNOTE-001 Investigators: Pembrolizumab for the treatment of non-small-cell lung cancer. N Engl J Med. 372:2018–2028. 2015. View Article : Google Scholar : PubMed/NCBI

4 

Sprung J, Scavonetto F, Yeoh TY, Kramer JM, Karnes RJ, Eisenach JH, Schroeder DR and Weingarten TN: Outcomes after radical prostatectomy for cancer: a comparison between general anesthesia and epidural anesthesia with fentanyl analgesia: a matched cohort study. Anesth Analg. 119:859–866. 2014. View Article : Google Scholar : PubMed/NCBI

5 

Klapper J and D'Amico TA: VATS versus open surgery for lung cancer resection: Moving toward a minimally invasive approach. J Natl Compr Canc Netw. 13:162–164. 2015. View Article : Google Scholar : PubMed/NCBI

6 

Masters GA, Temin S, Azzoli CG, Giaccone G, Baker S Jr, Brahmer JR, Ellis PM, Gajra A, Rackear N, Schiller JH, et al: American Society of Clinical Oncology Clinical Practice: Systemic Therapy for Stage IV Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 33:3488–3515. 2015. View Article : Google Scholar : PubMed/NCBI

7 

Travis WD, Travis LB and Devesa SS: Lung cancer. Cancer. 75 Suppl:191–202. 1995. View Article : Google Scholar : PubMed/NCBI

8 

Thomas A, Liu SV, Subramaniam DS and Giaccone G: Refining the treatment of NSCLC according to histological and molecular subtypes. Nat Rev Clin Oncol. 12:511–526. 2015. View Article : Google Scholar : PubMed/NCBI

9 

Grimminger PP, Maus MK, Schneider PM, Metzger R, Hölscher AH, Sugita H, Danenberg PV, Alakus H and Brabender J: Glutathione S-transferase PI (GST-PI) mRNA expression and DNA methylation is involved in the pathogenesis and prognosis of NSCLC. Lung Cancer. 78:87–91. 2012. View Article : Google Scholar : PubMed/NCBI

10 

Black RC and Khurshid H: NSCLC: An update of driver mutations, their role in pathogenesis and clinical significance. R I Med J (2013). 98:25–28. 2015.PubMed/NCBI

11 

Van Der Steen N, Rolfo C, Giovannetti E, Reclusa P, Peters GJ and Pauwels P: P2.09: cMET in NSCLC: Expression, amplification and mutations: track: biology and pathogenesis. J Thorac Oncol. 11:S221–S222. 2016. View Article : Google Scholar : PubMed/NCBI

12 

Seok Y, Cho S, Lee JY, Yang HC, Kim K and Jheon S: The effect of postoperative change in bronchial angle on postoperative pulmonary function after upper lobectomy in lung cancer patients. Interact Cardiovasc Thorac Surg. 18:183–188. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Cheng YD, Duan CJ, Dong S, Zhang H, Zhang SK, Wang SQ and Zhang CF: Clinical controlled comparison between lobectomy and segmental resection for patients over 70 years of age with clinical stage I non-small cell lung cancer. Eur J Surg Oncol. 38:1149–1155. 2012. View Article : Google Scholar : PubMed/NCBI

14 

Laursen LØ, Petersen RH, Hansen HJ, Jensen TK, Ravn J and Konge L: Video-assisted thoracoscopic surgery lobectomy for lung cancer is associated with a lower 30-day morbidity compared with lobectomy by thoracotomy. Eur J Cardiothorac Surg. 49:870–875. 2016. View Article : Google Scholar : PubMed/NCBI

15 

Goto T, Kadota Y, Mori T, Yamashita S, Horio H, Nagayasu T and Iwasaki A: Video-assisted thoracic surgery for pneumothorax: Republication of a systematic review and a proposal by the guideline committee of the Japanese association for chest surgery 2014. Gen Thorac Cardiovasc Surg. 63:8–13. 2015. View Article : Google Scholar : PubMed/NCBI

16 

Hong Y and Rurong W: Systemic and alveolar inflammatory response in the dependent and nondependent lung in patients undergoing lung resection surgery. Eur J Anaesthesiol. 33:63–64. 2016. View Article : Google Scholar : PubMed/NCBI

17 

Zhang J, Wang X, Zhang Y, Wu J and Zhou N: Leucine-rich repeats and immunoglobulin-like domains protein 1 and fascin actin-bundling protein 1 expression in nonsmall cell lung cancer. J Cancer Res Ther. 12 Suppl:C248–C251. 2016. View Article : Google Scholar : PubMed/NCBI

18 

Feng Q, Wei H, Morihara J, Stern J, Yu M, Kiviat N, Hellstrom I and Hellstrom KE: Th2 type inflammation promotes the gradual progression of HPV-infected cervical cells to cervical carcinoma. Gynecol Oncol. 127:412–419. 2012. View Article : Google Scholar : PubMed/NCBI

19 

Kayhan Erdogan G, Gul M, Kayhan B, Gedik E, Ozgul U, Kurtoglu EL, Durmus M and Ersoy MÖ: Dexmedetomidine ameliorates TNBS-induced colitis by inducing immunomodulator effect. J Surg Res. 183:733–741. 2013. View Article : Google Scholar : PubMed/NCBI

20 

Jackute J, Zemaitis M, Pranys D, Sitkauskiene B, Miliauskas S, Bajoriunas V, Lavinskiene S and Sakalauskas R: The prognostic influence of tumor infiltrating Foxp3(+)CD4(+), CD4(+) and CD8(+) T cells in resected non-small cell lung cancer. J Inflamm (Lond). 12:632015. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Ding N, Zhou N, Li Q, Ren G and Zhou M: Analysis of middle- and long-term efficacy of thoracoscope-assisted segmental resection of the lung on non-small cell lung cancer in the early stage. Oncol Lett 15: 3662-3668, 2018.
APA
Ding, N., Zhou, N., Li, Q., Ren, G., & Zhou, M. (2018). Analysis of middle- and long-term efficacy of thoracoscope-assisted segmental resection of the lung on non-small cell lung cancer in the early stage. Oncology Letters, 15, 3662-3668. https://doi.org/10.3892/ol.2018.7789
MLA
Ding, N., Zhou, N., Li, Q., Ren, G., Zhou, M."Analysis of middle- and long-term efficacy of thoracoscope-assisted segmental resection of the lung on non-small cell lung cancer in the early stage". Oncology Letters 15.3 (2018): 3662-3668.
Chicago
Ding, N., Zhou, N., Li, Q., Ren, G., Zhou, M."Analysis of middle- and long-term efficacy of thoracoscope-assisted segmental resection of the lung on non-small cell lung cancer in the early stage". Oncology Letters 15, no. 3 (2018): 3662-3668. https://doi.org/10.3892/ol.2018.7789
Copy and paste a formatted citation
x
Spandidos Publications style
Ding N, Zhou N, Li Q, Ren G and Zhou M: Analysis of middle- and long-term efficacy of thoracoscope-assisted segmental resection of the lung on non-small cell lung cancer in the early stage. Oncol Lett 15: 3662-3668, 2018.
APA
Ding, N., Zhou, N., Li, Q., Ren, G., & Zhou, M. (2018). Analysis of middle- and long-term efficacy of thoracoscope-assisted segmental resection of the lung on non-small cell lung cancer in the early stage. Oncology Letters, 15, 3662-3668. https://doi.org/10.3892/ol.2018.7789
MLA
Ding, N., Zhou, N., Li, Q., Ren, G., Zhou, M."Analysis of middle- and long-term efficacy of thoracoscope-assisted segmental resection of the lung on non-small cell lung cancer in the early stage". Oncology Letters 15.3 (2018): 3662-3668.
Chicago
Ding, N., Zhou, N., Li, Q., Ren, G., Zhou, M."Analysis of middle- and long-term efficacy of thoracoscope-assisted segmental resection of the lung on non-small cell lung cancer in the early stage". Oncology Letters 15, no. 3 (2018): 3662-3668. https://doi.org/10.3892/ol.2018.7789
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