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Article

Expression pattern of human SERPINE2 in a variety of human tumors

  • Authors:
    • Ying Yang
    • Xiangke Xin
    • Xing Fu
    • Danmei Xu
  • View Affiliations / Copyright

    Affiliations: Department of Haematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China
  • Pages: 4523-4530
    |
    Published online on: January 18, 2018
       https://doi.org/10.3892/ol.2018.7819
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Abstract

Serine proteinase inhibitor, clade E member 2 (SERPINE2), also known as protease nexin‑1 (PN‑1), is a member of the serpin family. Despite several reported roles of SERPINE2 in tumor development the histological distribution of SERPINE2 and its expression levels in a large variety of tumors remains unclear. Through expressed sequence tag database analysis, immunohistochemical staining of tissue microarrays and a literature review, it was revealed that SERPINE2 expression varied according to growth stages and tissue types. SERPINE2 is differentially expressed in a number of tumors and their normal tissue counterparts. SERPINE2 is identified most abundantly in adenocarcinomas. SERPINE2 serves diverse roles in a variety of tumors and therefore may serve as a promising biomarker for tumor diagnosis and prognosis.
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Copy and paste a formatted citation
Spandidos Publications style
Yang Y, Xin X, Fu X and Xu D: Expression pattern of human SERPINE2 in a variety of human tumors. Oncol Lett 15: 4523-4530, 2018.
APA
Yang, Y., Xin, X., Fu, X., & Xu, D. (2018). Expression pattern of human SERPINE2 in a variety of human tumors. Oncology Letters, 15, 4523-4530. https://doi.org/10.3892/ol.2018.7819
MLA
Yang, Y., Xin, X., Fu, X., Xu, D."Expression pattern of human SERPINE2 in a variety of human tumors". Oncology Letters 15.4 (2018): 4523-4530.
Chicago
Yang, Y., Xin, X., Fu, X., Xu, D."Expression pattern of human SERPINE2 in a variety of human tumors". Oncology Letters 15, no. 4 (2018): 4523-4530. https://doi.org/10.3892/ol.2018.7819
Copy and paste a formatted citation
x
Spandidos Publications style
Yang Y, Xin X, Fu X and Xu D: Expression pattern of human SERPINE2 in a variety of human tumors. Oncol Lett 15: 4523-4530, 2018.
APA
Yang, Y., Xin, X., Fu, X., & Xu, D. (2018). Expression pattern of human SERPINE2 in a variety of human tumors. Oncology Letters, 15, 4523-4530. https://doi.org/10.3892/ol.2018.7819
MLA
Yang, Y., Xin, X., Fu, X., Xu, D."Expression pattern of human SERPINE2 in a variety of human tumors". Oncology Letters 15.4 (2018): 4523-4530.
Chicago
Yang, Y., Xin, X., Fu, X., Xu, D."Expression pattern of human SERPINE2 in a variety of human tumors". Oncology Letters 15, no. 4 (2018): 4523-4530. https://doi.org/10.3892/ol.2018.7819
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