|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
Statistics, 2017. CA Cancer J Clin. 67:7–30. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Rosen DG, Yang G, Liu G, Mercado-Uribe I,
Chang B, Xiao XS, Zheng J, Xue FX and Liu J: Ovarian cancer:
Pathology, biology and disease models. Front Biosci (Landmark Ed).
14:2089–2102. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
4
|
Leamon CP, Lovejoy CD and Nguyen B:
Patient selection and targeted treatment in the management of
platinum-resistant ovarian cancer. Pharmgenomics Pers Med.
6:113–125. 2013.PubMed/NCBI
|
|
5
|
Ingham PW and Placzek M: Orchestrating
ontogenesis: Variations on a theme by sonic hedgehog. Nat Rev
Genet. 1–850. 2006.
|
|
6
|
Choudhry Z, Rikani AA, Choudhry AM, Tariq
S, Zakaria F, Asghar MW, Sarfraz MK, Haider K, Shafiq AA and
Mobassarah NJ: Sonic hedgehog signalling pathway: A complex
network. Ann Neurosci. 21:28–31. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Xie J, Bartels CM, Barton SW and Gu D:
Targeting hedgehog signaling in cancer: Research and clinical
developments. Onco Targets Ther. 6:1425–1435. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Hahn H, Wicking C, Zaphiropoulous PG,
Gailani MR, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E,
Unden AB, Gillies S, et al: Mutations of the human homolog of
Drosophila patched in the nevoid basal cell carcinoma syndrome.
Cell. 85:841–851. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Johnson RL, Rothman AL, Xie J, Goodrich
LV, Bare JW, Bonifas JM, Quinn AG, Myers RM, Cox DR, Epstein EH Jr
and Scott MP: Human homolog of patched, a candidate gene for the
basal cell nevus syndrome. Science. 272:1668–1671. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Reifenberger J, Wolter M, Knobbe CB,
Köhler B, Schönicke A, Scharwächter C, Kumar K, Blaschke B, Ruzicka
T and Reifenberger G: Somatic mutations in the PTCH, SMOH, SUFUH
and TP53 genes in sporadic basal cell carcinomas. Br J Dermatol.
152:43–51. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Couveprivat S, Bouadjar B, Avril MF,
Sarasin A and Daya-Grosjean L: Significantly high levels of
ultraviolet-specific mutations in the smoothened gene in basal cell
carcinomas from DNA repair-deficient xeroderma pigmentosum
patients. Cancer Res. 62:7186–7189. 2002.PubMed/NCBI
|
|
12
|
Tostar U, Malm CJ, Meis-Kindblom JM,
Kindblom LG, Toftgård R and Undén AB: Deregulation of the hedgehog
signalling pathway: A possible role for the PTCH and SUFU genes in
human rhabdomyoma and rhabdomyosarcoma development. J Pathol.
208:17–25. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Pressey JG, Anderson JR, Crossman DK,
Lynch JC and Barr FG: Hedgehog pathway activity in pediatric
embryonal rhabdomyosarcoma and undifferentiated sarcoma: A report
from the children's oncology group. Pediatr Blood Cancer.
57:930–938. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Aavikko M, Li SP, Saarinen S, Alhopuro P,
Kaasinen E, Morgunova E, Li Y, Vesanen K, Smith MJ, Evans DG, et
al: Loss of SUFU function in familial multiple meningioma. Am J Hum
Genet. 91:520–526. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Fei DL, Sanchez-Mejias A, Wang Z, Flaveny
C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C,
Briegel KJ, et al: Hedgehog signaling regulates bladder cancer
growth and tumorigenicity. Cancer Res. 72:4449–4458. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Bhattacharya R, Kwon J, Ali B, Wang E,
Patra S, Shridhar V and Mukherjee P: Role of hedgehog signaling in
ovarian cancer. Clin Cancer Res. 14:7659–7666. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Yang L, He J, Huang S, Zhang X, Bian Y, He
N, Zhang H and Xie J: Activation of hedgehog signaling is not a
frequent event in ovarian cancers. Mol Cancer. 8:1122009.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Chen Y, Bieber MM and Teng NN: Hedgehog
signaling regulates drug sensitivity by targeting ABC transporters
ABCB1 and ABCG2 in epithelial ovarian cancer. Mol Carcinog.
53:625–634. 2014.PubMed/NCBI
|
|
19
|
Chen X, Horiuchi A, Kikuchi N, Osada R,
Yoshida J, Shiozawa T and Konishi I: Hedgehog signal pathway is
activated in ovarian carcinomas, correlating with cell
proliferation: It's inhibition leads to growth suppression and
apoptosis. Cancer Sci. 98:68–76. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Yang YB, Liu L, Wang YQ, Yang YX and Wan
XP: Expression of Hedgehog pathway in normal ovary and ovarian
cancer. J Shanghai Jiaotong Univ (Med Sci). 29:426–430. 2009.(In
Chinese).
|
|
21
|
Schmid S, Bieber M, Zhang F, Zhang M, He
B, Jablons D and Teng NN: Wnt and hedgehog gene pathway expression
in serous ovarian cancer. Int J Gynecol Cancer. 21:975–980. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Li H, Li J and Feng L: Hedgehog signaling
pathway as a therapeutic target for ovarian cancer. Cancer
Epidemiol. 40:152–157. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Rumjanek VM, Vidal RS and Maia RC:
Multidrug resistance in chronic myeloid leukaemia: How much can we
learn from MDR-CML cell lines? Biosci Rep. 33:e000812013.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Queiroz KC, Ruela-de-Sousa RR, Fuhler GM,
Aberson HL, Ferreira CV, Peppelenbosch MP and Spek CA: Hedgehog
signaling maintains chemoresistance in myeloid leukemic cells.
Oncogene. 29:6314–6322. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Chen XL, Cheng QY, She MR, Wang Q, Huang
XH, Cao LQ, Fu XH and Chen JS: Expression of sonic hedgehog
signaling components in hepatocellular carcinoma and
cyclopamine-induced apoptosis through Bcl-2 downregulation in
vitro. Arch Med Res. 41:315–323. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Guo J, Gao J, Li Z, Gong Y, Man X, Jin J
and Wu H: Adenovirus vector-mediated Gli1 siRNA induces growth
inhibition and apoptosis in human pancreatic cancer with
Smo-dependent or Smo-independent Hh pathway activation in vitro and
in vivo. Cancer Lett. 339:185–194. 2013. View Article : Google Scholar : PubMed/NCBI
|
