Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
April-2018 Volume 15 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
April-2018 Volume 15 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Clinical characteristics and surgical outcomes of solitary spinal epidural cavernous angiomas

  • Authors:
    • Tao Yang
    • Fei Wang
    • Chaoshi Niu
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui 230001, P.R. China
  • Pages: 6036-6042
    |
    Published online on: February 12, 2018
       https://doi.org/10.3892/ol.2018.8024
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The majority of spinal cavernous angiomas (CAs) originate from the vertebral bodies with or without epidural space extension. Solitary epidural CAs are rare. In the present study, we retrospectively reviewed the records of 12 patients who underwent microsurgery for solitary spinal epidural CAs. All patients had performed pre‑ and postoperative magnetic resonance imaging. The patients were 7 females and 5 males with the mean age of 52.1 years. Two tumors were located in the cervicothoracic spine, nine in the thoracic spine and one in the lumbar spine, respectively. Solitary epidural CAs generally exhibited isointensity on T1‑weighted images and hyperintesity on T2‑weighted images. Contrast‑enhanced T1‑weighted images showed homogeneous markedly enhancement. Gross total resection (GTR) was achieved in 11 cases, and subtotal resection (STR) was achieved in 1 case. During an average follow up of 35.9 months, neurological function was improved in 11 patients and in one patient, preoperative status was maintained. No patient experienced tumor recurrence. These findings suggest that CAs should be considered in the differential diagnosis of spinal epidural lesions. Early surgery is advocated to prevent irreversible neurological deficits. When aggravated by a large amount of acute hemorrhage, neurological deterioration is usually acute and prompt surgical decompression is the optimal choice. Because of the excessive vascularity of CAs, en bloc resection is recommended. In addition, a good clinical outcome after GTR can be expected, and the risk of long‑term recurrence is low.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Tong X, Deng X, Li H, Fu Z and Xu Y: Clinical presentation and surgical outcome of intramedullary spinal cord cavernous malformations. J Neurosurg Spine. 16:308–314. 2012. View Article : Google Scholar : PubMed/NCBI

2 

Zevgaridis D, Büttner A, Weis S, Hamburger C and Reulen HJ: Spinal epidural cavernous hemangiomas. Report of three cases and review of the literature. J Neurosurg. 88:903–908. 1998. View Article : Google Scholar : PubMed/NCBI

3 

Talacchi A, Spinnato S, Alessandrini F, Iuzzolino P and Bricolo A: Radiologic and surgical aspects of pure spinal epidural cavernous angiomas. Report on 5 cases and review of the literature. Surg Neurol. 52:198–203. 1999. View Article : Google Scholar : PubMed/NCBI

4 

Aoyagi N, Kojima K and Kasai H: Review of spinal epidural cavernous hemangioma. Neurol Med Chir (Tokyo). 43:471–475. 2003. View Article : Google Scholar : PubMed/NCBI

5 

Hatiboglu MA, Iplikcioglu AC and Ozcan D: Epidural spinal cavernous hemangioma. Neurol Med Chir (Tokyo). 46:455–458. 2006. View Article : Google Scholar : PubMed/NCBI

6 

Caruso G, Galarza M, Borghesi I, Pozzati E and Vitale M: Acute presentation of spinal epidural cavernous angiomas: Case report. Neurosurgery. 60:E575–E576. 2007. View Article : Google Scholar : PubMed/NCBI

7 

Sohn MJ, Lee DJ, Jeon SR and Khang SK: Spinal radiosurgical treatment for thoracic epidural cavernous hemangioma presenting as radiculomyelopathy: Technical case report. Neurosurgery. 64:E1202–E1203. 2009. View Article : Google Scholar : PubMed/NCBI

8 

Sarikaya-Seiwert S, Gierga K, Wessalowski R, Steiger HJ and Hänggi D: Solitary spinal epidural cavernous angiomas in children presenting with acute neurological symptoms caused by hemorrhage. J Neurosurg Pediatr. 5:89–93. 2010. View Article : Google Scholar : PubMed/NCBI

9 

Floeth F, Riemenschneider M and Herdmann J: Intralesional hemorrhage and thrombosis without rupture in a pure spinal epidural cavernous angioma: A rare cause of acute lumbal radiculopathy. Eur Spine J. 19 Suppl 2:S193–S196. 2010. View Article : Google Scholar : PubMed/NCBI

10 

Sanghvi D, Munshi M, Kulkarni B and Kumar A: Dorsal spinal epidural cavernous hemangioma. J Craniovertebr Junction Spine. 1:122–125. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Saracen A and Kotwica Z: Thoracic spinal epidural cavernous haemangioma with an acute onset: Case report and the review of the literature. Clin Neurol Neurosurg. 115:799–801. 2013. View Article : Google Scholar : PubMed/NCBI

12 

Sharma MS, Borkar SA, Kumar A, Sharma MC, Sharma BS and Mahapatra AK: Thoracic extraosseous, epidural, cavernous hemangioma: Case report and review of literature. J Neurosci Rural Pract. 4:309–312. 2013. View Article : Google Scholar : PubMed/NCBI

13 

Bayri Y, Ekşi MŞ, Yalçınkaya Koç D and Konya D: Spinal epidural cavernous angioma: Two case reports and review of the literature. Acta Orthop Traumatol Turc. 49:459–464. 2015.PubMed/NCBI

14 

Feng J, Xu YK, Li L, Yang RM, Ye XH, Zhang N, Yu T and Lin BQ: MRI diagnosis and preoperative evaluation for pure epidural cavernous hemangiomas. Neuroradiology. 51:741–747. 2009. View Article : Google Scholar : PubMed/NCBI

15 

Zhong W, Huang S, Chen H, Sun H, Cai B, Liu Y and You C: Pure spinal epidural cavernous hemangioma. Acta Neurochir (Wien). 154:739–745. 2012. View Article : Google Scholar : PubMed/NCBI

16 

Khalatbari MR, Abbassioun K and Amirjmshidi A: Solitary spinal epidural cavernous angioma: Report of nine surgically treated cases and review of the literature. Eur Spine J. 22:542–547. 2013. View Article : Google Scholar : PubMed/NCBI

17 

Li TY, Xu YL, Yang J, Wang J and Wang GH: Primary spinal epidural cavernous hemangioma: Clinical features and surgical outcome in 14 cases. J Neurosurg Spine. 22:39–46. 2015. View Article : Google Scholar : PubMed/NCBI

18 

Chiles BW III, Leonard MA, Choudhri HF and Cooper PR: Cervical spondylotic myelopathy: Patterns of neurological deficit and recovery after anterior cervical decompression. Neurosurgery. 44:762–770. 1999. View Article : Google Scholar : PubMed/NCBI

19 

Labauge P, Bouly S, Parker F, Gallas S, Emery E, Loiseau H, Lejeune JP, Lonjon M, Proust F, Boetto S, et al: Outcome in 53 patients with spinal cord cavernomas. Surg Neurol. 70:176–181. 2008. View Article : Google Scholar : PubMed/NCBI

20 

Barker FG III, Amin-Hanjani S, Butler WE, Lyons S, Ojemann RG, Chapman PH and Ogilvy CS: Temporal clustering of hemorrhages from untreated cavernous malformations of the central nervous system. Neurosurgery. 49:15–24. 2001. View Article : Google Scholar : PubMed/NCBI

21 

Gao W, Qiao X, Ma S, Ma J, Dong X, Qin T and Fang Q: Contribution of skin trauma to infantile skin hemangioma. Med Hypotheses. 76:512–513. 2011. View Article : Google Scholar : PubMed/NCBI

22 

Demir MK, Ozdemir H, Unlu E, Temizöz O and Genchellac H: Differential diagnosis of spinal epidural meningioma and hemangioma at MR imaging. Radiology. 244:9332007. View Article : Google Scholar : PubMed/NCBI

23 

Uchida K, Yayama T, Nakajima H, Hirai T, Kobayashi S, Chen K, Guerrero AR and Baba H: Microsurgical resection of cavernous haemangioma around the thoracic neuroforamen: A case report. J Orthop Surg (Hong Kong). 18:370–373. 2010. View Article : Google Scholar : PubMed/NCBI

24 

Demachi H, Takashima T, Kadoya M, Suzuki M, Konishi H, Tomita K, Yonezawa K and Ubukata A: MR imaging of spinal neurinomas with pathological correlation. J Comput Assist Tomogr. 14:250–254. 1990. View Article : Google Scholar : PubMed/NCBI

25 

Wu L, Yang T, Deng X, Yang C, Zhao L, Yao N, Fang J, Wang G, Yang J and Xu Y: Spinal extradural en plaque meningiomas: Clinical features and long-term outcomes of 12 cases. J Neurosurg Spine. 21:892–898. 2014. View Article : Google Scholar : PubMed/NCBI

26 

Gelabert-González M and García-Allut A: Spinal extradural angiolipoma: Report of two cases and review of the literature. Eur Spine J. 18:324–335. 2009. View Article : Google Scholar : PubMed/NCBI

27 

Caroli E, Acqui M, Trasimeni G, Di Stefano D and Ferrante L: A case of intraroot cauda equina cavernous angioma: Clinical considerations. Spinal Cord. 45:318–321. 2007. View Article : Google Scholar : PubMed/NCBI

28 

Lee JW, Cho EY, Hong SH, Chung HW, Kim JH, Chang KH, Choi JY, Yeom JS and Kang HS: Spinal epidural hemangiomas: Various types of MR imaging features with histopathologic correlation. AJNR Am J Neuroradiol. 28:1242–1248. 2007. View Article : Google Scholar : PubMed/NCBI

29 

Gencpinar P, Açıkbaş SC, Nur BG, Karaali K, Arslan M, Gurer EI, Duman O and Haspolat S: Epidural capillary hemangioma: A review of the literature. Clin Neurol Neurosurg. 126:99–102. 2014. View Article : Google Scholar : PubMed/NCBI

30 

Padovani R, Acciarri N, Giulioni M, Pantieri R and Foschini MP: Cavernous angiomas of the spinal district: Surgical treatment of 11 patients. Eur Spine J. 6:298–303. 1997. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Yang T, Wang F and Niu C: Clinical characteristics and surgical outcomes of solitary spinal epidural cavernous angiomas. Oncol Lett 15: 6036-6042, 2018.
APA
Yang, T., Wang, F., & Niu, C. (2018). Clinical characteristics and surgical outcomes of solitary spinal epidural cavernous angiomas. Oncology Letters, 15, 6036-6042. https://doi.org/10.3892/ol.2018.8024
MLA
Yang, T., Wang, F., Niu, C."Clinical characteristics and surgical outcomes of solitary spinal epidural cavernous angiomas". Oncology Letters 15.4 (2018): 6036-6042.
Chicago
Yang, T., Wang, F., Niu, C."Clinical characteristics and surgical outcomes of solitary spinal epidural cavernous angiomas". Oncology Letters 15, no. 4 (2018): 6036-6042. https://doi.org/10.3892/ol.2018.8024
Copy and paste a formatted citation
x
Spandidos Publications style
Yang T, Wang F and Niu C: Clinical characteristics and surgical outcomes of solitary spinal epidural cavernous angiomas. Oncol Lett 15: 6036-6042, 2018.
APA
Yang, T., Wang, F., & Niu, C. (2018). Clinical characteristics and surgical outcomes of solitary spinal epidural cavernous angiomas. Oncology Letters, 15, 6036-6042. https://doi.org/10.3892/ol.2018.8024
MLA
Yang, T., Wang, F., Niu, C."Clinical characteristics and surgical outcomes of solitary spinal epidural cavernous angiomas". Oncology Letters 15.4 (2018): 6036-6042.
Chicago
Yang, T., Wang, F., Niu, C."Clinical characteristics and surgical outcomes of solitary spinal epidural cavernous angiomas". Oncology Letters 15, no. 4 (2018): 6036-6042. https://doi.org/10.3892/ol.2018.8024
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team