Malignant lymphoma of the uterine cervix presumptively diagnosed by Pap smear: A case report

Koyanagi,Takahiro; Kondo,Haruhiko; Toyama,Atsushi; Ando,Miho; Imaoka,Sakiko; Inamura,Masayo; Yamamoto,Hiroko; Nakamura,Sumie; To,Yoko; Fukami,Tatsuya; Goto,Maki; Tsujioka,Hiroshi; Eguchi,Fuyuki

doi:10.3892/ol.2018.8146

May-2018 Volume 15 Issue 5

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May-2018 Volume 15 Issue 5

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Case Report

Malignant lymphoma of the uterine cervix presumptively diagnosed by Pap smear: A case report

Authors:
- Takahiro Koyanagi
- Haruhiko Kondo
- Atsushi Toyama
- Miho Ando
- Sakiko Imaoka
- Masayo Inamura
- Hiroko Yamamoto
- Sumie Nakamura
- Yoko To
- Tatsuya Fukami
- Maki Goto
- Hiroshi Tsujioka
- Fuyuki Eguchi
View Affiliations / Copyright

Affiliations: Department of Obstetrics and Gynecology, ASO Iizuka Hospital, Iizuka, Fukuoka 820‑8505, Japan
Pages: 6678-6680
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Published online on: March 1, 2018

https://doi.org/10.3892/ol.2018.8146
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Abstract

Malignant lymphoma of the uterine cervix is exceedingly rare and is difficult to diagnose by cervical cytology. The current study presents a case of malignant lymphoma of the uterine cervix that was presumptively diagnosed by cervical cancer screening in which the patient had no clinical symptoms. The anterior lip of the uterine cervix was occupied by a macroscopic hemorrhagic tumor. The obtained tumor cells exhibited typical cytological features of malignant lymphoma and were positive for CD20. The final diagnosis was diffuse large B cell lymphoma of the uterine cervix, stage IIEA (Ann Arbor classification). The patient received 6 courses of R‑CHOP chemotherapy and achieved complete remission. Despite its rarity, the possibility of malignant lymphoma should be considered while screening for cervical cancers using Pap smears. The Pap test screening may be useful for the early diagnosis of malignant lymphoma of the uterine cervix in certain cases. By reaching a rapid and accurate diagnosis, immediate treatment may be initiated and surgery may be avoided.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Malignant lymphoma of the uterine cervix presumptively diagnosed by Pap smear: A case report

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