|
1
|
Alejandro F, Josep ML and Jordi B:
Hepatocellular carcinoma. Lancet. 379:1245–1255. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Chen WQ, Zheng RS, Baade PD, Zhang SW,
Zeng HM, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in
China, 2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Siegel R, Naishadham D and Jemal A: Cancer
statistics, 2013. CA Cancer J Clin. 63:11–30. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ogunwobi OO and Liu C: Therapeutic and
prognostic importance of epithelial-mesenchymal transition in liver
cancers: Insights from experimental models. Crit Rev Oncol Hematol.
83:319–328. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Inokawa Y, Nomoto S, Hishida M, Hayashi M,
Kanda M, Nishikawa Y, Takeda S, Sugimoto H, Fujii T, Yamada S,
Hayashi M, Kanda M, Nishikawa Y, Takeda S, Sugimoto H, Fujii T,
Yamada S, Kodera Y, et al: Detection of doublecortin
domain-containing 2 (DCDC2), a new candidate tumor suppressor gene
of hepatocellular carcinoma by triple combination array analysis. J
Exp Clin Cancer Res. 32:652013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Bannister AJ and Kouzarides T: Regulation
of chromatin by histone modifications. Cell Res. 21:381–395. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ang YS, Tsai SY, Lee DF, Monk J, Su J,
Ratnakumar K, Ding J, Ge Y, Darr H, Chang B, et al: Wdr5 mediates
self-renewal and reprogramming via the embryonic stem cell core
transcriptional network. Cell. 145:183–197. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Wysocka J, Swigut T, Milne TA, Dou Y,
Zhang X, Burlingame AL, Roeder RG, Brivanlou AH and Allis CD: WDR5
associates with histone H3 methylated at K4 and is essential for H3
K4 methylation and vertebrate development. Cell. 121:859–872. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Trievel RC and Shilatifard A: WDR5, a
complexed protein. Nat Struct Mol Biol. 16:678–680. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Dou Y, Milne TA, Ruthenburg AJ, Lee S, Lee
JW, Verdine GL, Allis CD and Roeder RG: Regulation of MLL1 H3K4
methyltransferase activity by its core components. Nat Struct Mol
Biol. 13:713–719. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
11
|
Shinsky SA, Hu M, Vought VE, Ng SB,
Bamshad MJ, Shendure J and Cosgrove MS: A non-active-site SET
domain surface crucial for the interaction of MLL1 and the
RbBP5/Ash2L heterodimer within MLL family core complexes. J Mol
Biol. 426:2283–2299. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Schuetz A, Allali-Hassani A, Martín F,
Loppnau P, Vedadi M, Bochkarev A, Plotnikov AN, Arrowsmith CH and
Min J: Structural basis for molecular recognition and presentation
of histone H3 by WDR5. EMBO J. 25:4245–4252. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Kim JY, Banerjee T, Vinckevicius A, Luo Q,
Parker JB, Baker MR, Radhakrishnan I, Wei JJ, Barish GD and
Chakravarti D: A role for WDR5 in integrating threonine 11
phosphorylation to lysine 4 methylation on histone H3 during
androgen signaling and in prostate cancer. Mol Cell. 54:613–625.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Chen X, Xie WB, Gu P, Cai QQ, Wang B, Xie
Y, Dong W, He W, Zhong G, Lin T and Huang J: UpregulatedWDR5
promotes proliferation, self-renewal and chemoresistance in bladder
cancer via mediating H3K4 trimethylation. Sci Rep. 5:82932015.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Ge Z, Song EJ, Kawasawa YI, Li J, Dovat S
and Song C: WDR5 high expression and its effect on tumorigenesis in
leukemia. Oncotarget. 7:37740–37754. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Dai X, Guo W, Zhan C, Liu X, Bai Z and
Yang Y: WDR5 expression is prognostic of breast cancer outcome.
PLoS One. 10:e01249642015. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Wittekind C, Compton CC, Greene FL and
Sobin LH: TNM residual tumor classifcation revisited. Cancer.
94:2511–2516. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zhou L, Rui JA, Ye DX, Wang SB, Chen SG
and Qu Q: Edmondson-steiner grading increases the predictive
efficiency of TNM staging for long-term survival of patients with
hepatocellular carcinoma after curative resection. World J Surg.
32:1748–1756. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Chen Z, Yang P, Li W, He F, Wei J, Zhang
T, Zhong J, Chen H and Cao J: Expression of EZH2 is associated with
poor outcome in colorectal cancer. Oncol Lett. 15:2953–2961.
2018.PubMed/NCBI
|
|
20
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
He C, Xu J, Zhang J, Xie D, Ye H, Xiao Z,
Cai M, Xu K, Zeng Y, Li H and Wang J: High expression of
trimethylated histone H3 lysine 4 is associated with poor prognosis
in hepatocellular carcinoma. Hum Pathol. 43:1425–1435. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Margueron R and Reinberg D: The Polycomb
complex PRC2 and its mark in life. Nature. 469:343–349. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Weikert S, Christoph F, Kollermann J,
Müller M, Schrader M, Miller K and Krause H: Expression levels of
the EZH2 polycomb transcriptional repressor correlate with
aggressiveness and invasive potential of bladder carcinomas. Int J
Mol Med. 16:349–353. 2005.PubMed/NCBI
|
|
24
|
Bachmann IM, Halvorsen OJ, Collett K,
Stefansson IM, Straume O, Haukaas SA, Salvesen HB, Otte AP and
Akslen LA: EZH2 expression is associated with high proliferation
rate and aggressive tumor subgroups in cutaneous melanoma and
cancers of the endometrium, prostate, and breast. J Clin Oncol.
24:268–273. 2006. View Article : Google Scholar : PubMed/NCBI
|
