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Article Open Access

Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography

  • Authors:
    • Rui Fang
    • Yong Yang
    • Haicheng Han
    • Xiaoqing Fu
    • Liwen Dong
    • Baisheng Xie
    • Wei Lu
    • Chenyang Ma
    • Feng Cui
    • Jian Hu
    • Jun Wang
  • View Affiliations / Copyright

    Affiliations: Guangxing Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310007, P.R. China, School of Medicine, Hangzhou Normal University, Hangzhou, Zhejiang 310018, P.R. China, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, P.R. China, The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China, Peking University People's Hospital, Beijing 100044, P.R. China
    Copyright: © Fang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2483-2489
    |
    Published online on: June 6, 2018
       https://doi.org/10.3892/ol.2018.8921
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Abstract

Risk factors for stage I lung adenocarcinoma were analyzed using low‑dose high‑resolution computed tomography (CT). The patients were divided into case group (stage I lung adenocarcinoma patients) and control group (benign pulmonary nodules patients). All patients were subjected to low‑dose high‑resolution CT. Multiple linear regression was performed to analyze the CT imaging features of the two groups. Stage I lung adenocarcinoma patients were significantly associated with nodular site (X3, upper left lobe) [95% CI (1.796, 54.695), p=0.008], nodule type (X4) (p<0.001), nodule size (X5) [95% CI (0.614, 0.803), p<0.001], spicule sign (X7) [95% CI (0.029, 0.580), p=0.008], lobulation sign (X8) [95% CI (0.048, 0.673), p=0.011]. The stepwise regression equation is: Logistic (p) = ‑12.009 + 2.294X3 ‑ 0.327X4 ‑ 0.354X5 ‑ 2.042X7 ‑ 1.713X8. Risk factors of low‑dose and high‑resolution CT imaging for patients with stage I lung adenocarcinoma are nodular site (upper left lobe), nodule type, nodule size, spicule sign, and lobulation sign.
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Copy and paste a formatted citation
Spandidos Publications style
Fang R, Yang Y, Han H, Fu X, Dong L, Xie B, Lu W, Ma C, Cui F, Hu J, Hu J, et al: Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography. Oncol Lett 16: 2483-2489, 2018.
APA
Fang, R., Yang, Y., Han, H., Fu, X., Dong, L., Xie, B. ... Wang, J. (2018). Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography. Oncology Letters, 16, 2483-2489. https://doi.org/10.3892/ol.2018.8921
MLA
Fang, R., Yang, Y., Han, H., Fu, X., Dong, L., Xie, B., Lu, W., Ma, C., Cui, F., Hu, J., Wang, J."Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography". Oncology Letters 16.2 (2018): 2483-2489.
Chicago
Fang, R., Yang, Y., Han, H., Fu, X., Dong, L., Xie, B., Lu, W., Ma, C., Cui, F., Hu, J., Wang, J."Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography". Oncology Letters 16, no. 2 (2018): 2483-2489. https://doi.org/10.3892/ol.2018.8921
Copy and paste a formatted citation
x
Spandidos Publications style
Fang R, Yang Y, Han H, Fu X, Dong L, Xie B, Lu W, Ma C, Cui F, Hu J, Hu J, et al: Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography. Oncol Lett 16: 2483-2489, 2018.
APA
Fang, R., Yang, Y., Han, H., Fu, X., Dong, L., Xie, B. ... Wang, J. (2018). Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography. Oncology Letters, 16, 2483-2489. https://doi.org/10.3892/ol.2018.8921
MLA
Fang, R., Yang, Y., Han, H., Fu, X., Dong, L., Xie, B., Lu, W., Ma, C., Cui, F., Hu, J., Wang, J."Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography". Oncology Letters 16.2 (2018): 2483-2489.
Chicago
Fang, R., Yang, Y., Han, H., Fu, X., Dong, L., Xie, B., Lu, W., Ma, C., Cui, F., Hu, J., Wang, J."Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography". Oncology Letters 16, no. 2 (2018): 2483-2489. https://doi.org/10.3892/ol.2018.8921
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