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[Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer

  • Authors:
    • Senthil Rajappa
    • Ashish Joshi
    • Dinesh C. Doval
    • Ullas Batra
    • Rejiv Rajendranath
    • Avinash Deo
    • Ghanshyam Biswas
    • Peush Bajpai
    • T. V.S. Tilak
    • Sriram Kane
    • Kishore Kumar
    • Manish Kumar
    • Avinash D. Talele
    • Prakash Devde
    • Ashutosh Gupta
    • Nisarg Joshi
    • Jaykumar Sejpal
    • Deepak Bunger
    • Mujtaba Khan
  • View Affiliations / Copyright

    Affiliations: Department of Medical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana 500034, India, Nanavati Hospital, Mumbai, Maharashtra 400056, India, Rajiv Gandhi Cancer Institute and Research Centre, Delhi 110085, India, Apollo Speciality Hospital, Chennai, Tamil Nadu 600096, India, Fortis SL Raheja Hospital, Mumbai, Maharashtra 400016, India, Sparsh Hospital, Bhubaneswar, Odisha 751007, India, Max Super Speciality Hospital, New Delhi 110017, India, Command Hospital, Bangalore, Karnataka 560007, India, Kane Hematology and Oncology Clinic, Nagpur, Maharashtra 440012, India, Command Hospital, Lucknow, Uttar Pradesh 226002, India, CHL Hospital, Indore, Madhya Pradesh 452008, India, Seth Nandlal Dhoot Hospital, Aurangabad, Maharashtra 431210, India, Government Medical College, Jammu, Jammu and Kashmir 180001, India, Intas Pharmaceuticals Ltd., Ahmedabad, Gujarat 380061, India
    Copyright: © Rajappa et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Pages: 3757-3769
    |
    Published online on: July 2, 2018
       https://doi.org/10.3892/ol.2018.9057
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Abstract

The management of breast cancer with advanced disease or metastasis is a common problem in India and other countries. A panel of 13 oncology experts deliberated on the sidelines of the 35th Indian Cooperative Oncology Network Conference held in Mumbai to formulate an expert opinion recommendation on the novel drug delivery system (NDDS) formulations in the treatment of metastatic breast cancer (MBC). The survey comprised of 39 questions related to limitations of conventional formulations and therapeutic positioning of NDDS formulations of docetaxel, paclitaxel and doxorubicin in the management of MBC. The experts used data from published literature and their practical experience to provide expert opinion and recommendations for use by the community oncologists. The experts opined that the newer NDDS formulations should provide a significant efficacy advantage in terms of overall survival and progression‑free survival, or demonstrate better tolerability when compared with conventional formulations. The newer NDDS formulations of taxanes should be considered in special circumstances such as diabetes, in patients who have had hypersensitivity reactions and in cases where steroids need to be avoided. The novel formulations of doxorubicin should be used in the elderly and in patients with borderline cardiac function.
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Copy and paste a formatted citation
Spandidos Publications style
Rajappa S, Joshi A, Doval DC, Batra U, Rajendranath R, Deo A, Biswas G, Bajpai P, Tilak TV, Kane S, Kane S, et al: [Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer. Oncol Lett 16: 3757-3769, 2018.
APA
Rajappa, S., Joshi, A., Doval, D.C., Batra, U., Rajendranath, R., Deo, A. ... Khan, M. (2018). [Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer. Oncology Letters, 16, 3757-3769. https://doi.org/10.3892/ol.2018.9057
MLA
Rajappa, S., Joshi, A., Doval, D. C., Batra, U., Rajendranath, R., Deo, A., Biswas, G., Bajpai, P., Tilak, T. V., Kane, S., Kumar, K., Kumar, M., Talele, A. D., Devde, P., Gupta, A., Joshi, N., Sejpal, J., Bunger, D., Khan, M."[Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer". Oncology Letters 16.3 (2018): 3757-3769.
Chicago
Rajappa, S., Joshi, A., Doval, D. C., Batra, U., Rajendranath, R., Deo, A., Biswas, G., Bajpai, P., Tilak, T. V., Kane, S., Kumar, K., Kumar, M., Talele, A. D., Devde, P., Gupta, A., Joshi, N., Sejpal, J., Bunger, D., Khan, M."[Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer". Oncology Letters 16, no. 3 (2018): 3757-3769. https://doi.org/10.3892/ol.2018.9057
Copy and paste a formatted citation
x
Spandidos Publications style
Rajappa S, Joshi A, Doval DC, Batra U, Rajendranath R, Deo A, Biswas G, Bajpai P, Tilak TV, Kane S, Kane S, et al: [Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer. Oncol Lett 16: 3757-3769, 2018.
APA
Rajappa, S., Joshi, A., Doval, D.C., Batra, U., Rajendranath, R., Deo, A. ... Khan, M. (2018). [Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer. Oncology Letters, 16, 3757-3769. https://doi.org/10.3892/ol.2018.9057
MLA
Rajappa, S., Joshi, A., Doval, D. C., Batra, U., Rajendranath, R., Deo, A., Biswas, G., Bajpai, P., Tilak, T. V., Kane, S., Kumar, K., Kumar, M., Talele, A. D., Devde, P., Gupta, A., Joshi, N., Sejpal, J., Bunger, D., Khan, M."[Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer". Oncology Letters 16.3 (2018): 3757-3769.
Chicago
Rajappa, S., Joshi, A., Doval, D. C., Batra, U., Rajendranath, R., Deo, A., Biswas, G., Bajpai, P., Tilak, T. V., Kane, S., Kumar, K., Kumar, M., Talele, A. D., Devde, P., Gupta, A., Joshi, N., Sejpal, J., Bunger, D., Khan, M."[Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer". Oncology Letters 16, no. 3 (2018): 3757-3769. https://doi.org/10.3892/ol.2018.9057
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