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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2018 Volume 16 Issue 3

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Anti‑inflammatory and antitumor action of hydrogen via reactive oxygen species (Review)

Ye Yang, Yaping Zhu, Xiaowei Xi
Pages: 2771-2776
Published online on: 26 June 2018

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Review

MicroRNA‑21: A promising biomarker for the prognosis and diagnosis of non‑small cell lung cancer (Review)

Wen Zheng, Juanjuan Zhao, Yijing Tao, Mengmeng Guo, Zhou Ya, Chao Chen, Nalin Qin, Jing Zheng, Junmin Luo, Lin Xu
Pages: 2777-2782
Published online on: 15 June 2018

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Case Report Open Access

Adenoid cystic carcinoma of the larynx in a 70-year-old patient: A case report

Filippo Ricciardiello, Raffaele Addeo, Antonella Miriam Di Lullo, Teresa Abate, Salvatore Mazzone, Flavia Oliva, Giovanni Motta, Michelle Caraglia, Massimo Mesolella
Pages: 2783-2788
Published online on: 18 June 2018

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Article Open Access

Gene therapy of renal cancer using recombinant adeno‑associated virus encoding human endostatin

Erlin Sun, Ruifa Han, Bingxin Lu
Pages: 2789-2796
Published online on: 28 June 2018

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Article Open Access

MEG‑3‑mediated Wnt/β‑catenin signaling pathway controls the inhibition of tunicamycin‑mediated viability in glioblastoma Retraction in /10.3892/ol.2025.15162

Xiangyu Cui, Dezhou Sun, Bin Shen, Xin Wang
Pages: 2797-2804
Published online on: 28 June 2018

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Article Open Access

Doxorubicin combined with Notch1‑targeting siRNA for the treatment of gastric cancer

Wei Zhou, Wei Tan, Xu Huang, Hong Gang Yu
Pages: 2805-2812
Published online on: 28 June 2018

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Article Open Access

Antitumor efficacy of the Runx2‑dendritic cell vaccine in triple‑negative breast cancer in vitro

Mi Tang, Yu Liu, Qiao‑Chu Zhang, Peng Zhang, Jue‑Kun Wu, Jia‑Ni Wang, Ying Ruan, Yong Huang
Pages: 2813-2822
Published online on: 21 June 2018

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Article Open Access

Overexpression of TPX2 is associated with progression and prognosis of prostate cancer

Jun Zou, Rui‑Yan Huang, Fu‑Neng Jiang, De‑Xiong Chen, Cong Wang, Zhao‑Dong Han, Yu‑Xiang Liang, Wei‑De Zhong
Pages: 2823-2832
Published online on: 25 June 2018

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Article Open Access

Liver receptor homologue 1, a novel prognostic marker in colon cancer patients

Cong Wu, Jin Feng, Ling Li, Yugang Wu, Haibin Xie, Yong Yin, Jing Ye, Zhong Li
Pages: 2833-2838
Published online on: 18 June 2018

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Article Open Access

Impact of liver tumor percutaneous radiofrequency ablation on circulating tumor cells

Yang Li, Na Huang, Chunlin Wang, Huanrong Ma, Minyu Zhou, Li Lin, Zhenhua Huang, Li Sun, Min Shi, Wangjun Liao
Pages: 2839-2850
Published online on: 25 June 2018

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Article Open Access

AG490 reverses phenotypic alteration of dendritic cells by bladder cancer cells

Weigang Xiu, Juan Ma, Ting Lei, Man Zhang
Pages: 2851-2856
Published online on: 27 June 2018

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Article Open Access

Wnt2 contributes to the progression of gastric cancer by promoting cell migration and invasion

Zhaoran Zhang, Jinyan Wang, Xiang Dong
Pages: 2857-2864
Published online on: 28 June 2018

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Article Open Access

Silencing long non‑coding RNA, differentiation antagonizing non‑protein coding RNA promotes apoptosis and inhibits tumor growth in colon cancer

Xiao‑Jin Yang, Jing‑Jing Zhao, Wei‑Jun Chen, Gen‑Gen Zhang, Wei Wang, Han‑Chuan Tao
Pages: 2865-2872
Published online on: 28 June 2018

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Article Open Access

Skp2 expression has different clinicopathological and prognostic implications in lung adenocarcinoma and squamous cell carcinoma

Kaize Zhong, Fan Yang, Qiuying Han, Jing Chen, Jun Wang
Pages: 2873-2880
Published online on: 20 June 2018

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Article Open Access

Overexpression of macrophage migration inhibitory factor and functionally‑related genes, D‑DT, CD74, CD44, CXCR2 and CXCR4, in glioblastoma

Mario Presti, Emanuela Mazzon, Maria Sofia Basile, Maria Cristina Petralia, Alessia Bramanti, Giuseppe Colletti, Placido Bramanti, Ferdinando Nicoletti, Paolo Fagone
Pages: 2881-2886
Published online on: 19 June 2018

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Article Open Access

Epstein‑Barr virus‑encoded microRNA BART7 downregulates major histocompatibility complex class I chain‑related peptide A and reduces the cytotoxicity of natural killer cells to nasopharyngeal carcinoma

Thian‑Sze Wong, Siqi Chen, Min‑Juan Zhang, Jimmy Yu‑Wai Chan, Wei Gao
Pages: 2887-2892
Published online on: 28 June 2018

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Article Open Access

VTIQ evaluates antitumor effects of NET‑1 siRNA by UTMD in HCC xenograft models

Xitian Liang, Bolin Wu, Haitao Shang, Xue Han, Hui Jing, Yixin Sun, Wen Cheng
Pages: 2893-2902
Published online on: 19 June 2018

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Article Open Access

SMOC1 silencing suppresses the angiotensin II‑induced myocardial fibrosis of mouse myocardial fibroblasts via affecting the BMP2/Smad pathway

Yize Wang, Xianming Wu
Pages: 2903-2910
Published online on: 19 June 2018

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Article Open Access

Tumor targeting with docosahexaenoic acid‑conjugated docetaxel for inhibiting lung cancer metastasis to bone

Shougang Jiang, Zhiguo Liu, Lei Wu, Yingjie Yuan, Yan Hu, Xingyao Zhang, Liang Wei, Yuangang Zu
Pages: 2911-2920
Published online on: 28 June 2018

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Article Open Access

Calcium gluconate alleviates the toxic effect of hydrofluoric acid on human dermal fibroblasts through the Wnt/β‑catenin pathway

Jinxia Peng, Rui Liu, Ling Peng, Hongtao Jia
Pages: 2921-2928
Published online on: 18 June 2018

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Article Open Access

Clinical characteristics and prognosis of pediatric patients with B cell acute lymphoblastic leukemia relapse

Xiaohong Zhang, Haixia Wu, Hong Fan, Baifang Su, Ge Zhang, Lin Dong
Pages: 2929-2934
Published online on: 18 June 2018

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Article Open Access

Prognostic value of IL‑6R mRNA in lung adenocarcinoma and squamous cell carcinoma

Bin Xu, Qu Chen, Cuihua Yue, Lei Lan, Jingting Jiang, Yueping Shen, Binfeng Lu
Pages: 2935-2948
Published online on: 28 June 2018

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Article Open Access

Resveratrol induces apoptosis in SGC‑7901 gastric cancer cells

Xiaoxue Wu, Yundan Xu, Biran Zhu, Qiang Liu, Qunfeng Yao, Gang Zhao
Pages: 2949-2956
Published online on: 28 June 2018

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Article Open Access

Medicinal supplement genipin induces p53 and Bax‑dependent apoptosis in colon cancer cells

Jingwang Ye, Jing Li, Xiangfeng Wang, Ling Li
Pages: 2957-2964
Published online on: 26 June 2018

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Article Open Access

Matrine inhibits TPC‑1 human thyroid cancer cells via the miR‑21/PTEN/Akt pathway

Lina Zhao, Xianyu Zhang, Shusen Cui
Pages: 2965-2970
Published online on: 21 June 2018

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Article Open Access

Clinical significance of tumor necrosis factor receptor 2 in middle and lower thoracic esophageal squamous cell carcinoma

Dong Yang, Ruidong Li, Huili Wang, Junye Wang, Ye Li, Hongbo Wang, Wei Wang, Zifeng Liu
Pages: 2971-2978
Published online on: 20 June 2018

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Case Report Open Access

Complete cure of a patient with HBV‑associated hepatocellular carcinoma with lung metastasis using interferon and survival up to 108 months: A case report and literature review

Fang Wang, Hongmin Lv, Yan Li, Tao Han, Hui Liu, Kefeng Jia, Fang Liu, Yanying Gao, Fengmei Wang
Pages: 2979-2988
Published online on: 28 June 2018

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Article Open Access

Clinical significance of chromodomain helicase/ATPase DNA binding protein 1‑like and human mutL homolog 1 gene expression in cholangiocarcinoma

Jingwen Hua, Shiniao Li, Changwen Huang
Pages: 2989-2994
Published online on: 28 June 2018

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Article Open Access

Extramedullary plasmacytoma of the larynx: Literature review and report of a case who subsequently developed acute myeloid leukemia

Shenglei Ge, Ganghua Zhu, Yan Yi
Pages: 2995-3004
Published online on: 19 June 2018

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Article Open Access

miR-16 targets SALL4 to repress the proliferation and migration of gastric cancer

Xuefeng Jiang, Zhe Wang
Pages: 3005-3012
Published online on: 20 June 2018

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Article Open Access

The knockdown of the Mediator complex subunit MED15 restrains urothelial bladder cancer cells' malignancy

Isabella Syring, Richard Weiten, Tim Müller, Doris Schmidt, Susanne Steiner, Glen Kristiansen, Stefan C. Müller, Jörg Ellinger
Pages: 3013-3021
Published online on: 25 June 2018

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Article Open Access

Immunological effects of a low‑dose cytarabine, aclarubicin and granulocyte‑colony stimulating factor priming regimen on a mouse leukemia model

Jinqiu Chen, Nan Yang, Hailing Liu, Huan Yao, Jin Wang, Yun Yang, Wanggang Zhang
Pages: 3022-3028
Published online on: 25 June 2018

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Article Open Access

Decreased expression level and DNA‑binding activity of specificity protein 1 via cyclooxygenase‑2 inhibition antagonizes radiation resistance, cell migration and invasion in radiation‑resistant lung cancer cells

Ruijun Liu, Qiang Tan, Qingquan Luo
Pages: 3029-3037
Published online on: 28 June 2018

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Article Open Access

MicroRNA‑30a suppresses the proliferation, migration and invasion of human renal cell carcinoma cells by directly targeting ADAM9 Retraction in /10.3892/ol.2024.14232

Lining Jiang, Yabin Liu, Can Ma, Binghui Li
Pages: 3038-3044
Published online on: 20 June 2018

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Article Open Access

Role of regulatory T cells and CD8+ T lymphocytes in the dissemination of circulating tumor cells in primary invasive breast cancer

Dandan Xue, Tiansong Xia, Jue Wang, Meihong Chong, Shui Wang, Chunhui Zhang
Pages: 3045-3053
Published online on: 19 June 2018

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Article Open Access

Burkitt lymphoma‑associated network construction and important network motif analysis

Kunhao Wang, Chao Ma, Chong Xing, Chin‑Ling Chen, Zhigang Chen, Yuxia Yao, Jianan Wang, Chunyu Tao
Pages: 3054-3062
Published online on: 21 June 2018

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Article Open Access

miR-106b targets DAB2 to promote hepatocellular carcinoma cell proliferation and metastasis

Chunhui Sun, Xun Yao, Qingyu Jiang, Xiuyong Sun
Pages: 3063-3069
Published online on: 15 June 2018

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Article Open Access

Role of PLK1 signaling pathway genes in gastrointestinal stromal tumors

Jen‑Shi Chen, Chun‑Nan Yeh, Chi‑Tung Cheng, Chueh‑Chuan Yen, Yen‑Yang Chen, Shih‑Chiang Huang, Kun‑Chun Chiang, Ta‑Sen Yeh, San‑Chi Chen, Ta‑Chung Chao, Muh‑Hwa Yang, Yee Chao
Pages: 3070-3082
Published online on: 21 June 2018

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Article Open Access

Anterior gradient 2 as a supervisory marker for tumor vessel normalization induced by anti‑angiogenic treatment

Fan Pan, Wei Li, Wende Yang, Xiao‑Yan Yang, Shuhao Liu, Xin Li, Xiaoxu Zhao, Hui Ding, Li Qin, Yunlong Pan
Pages: 3083-3091
Published online on: 20 June 2018

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Article Open Access

Screening and identification of key biomarkers in bladder carcinoma: Evidence from bioinformatics analysis

Meiqin Yan, Xuan Jing, Yina Liu, Xiangrong Cui
Pages: 3092-3100
Published online on: 21 June 2018

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Article Open Access

miR-185 inhibits cell migration and invasion of hepatocellular carcinoma through CDC42 Erratum in /10.3892/ol.2019.11186

Qingjun Zhang, Yun Chen, Ke Liu
Pages: 3101-3107
Published online on: 15 June 2018

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Article Open Access

Effect of chelidonine on growth, invasion, angiogenesis and gene expression in head and neck cancer cell lines

Ruth Herrmann, Jeanette Roller, Christine Polednik, Marianne Schmidt
Pages: 3108-3116
Published online on: 27 June 2018

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Article Open Access

Homogenously isoattenuating insulinoma on biphasic contrast‑enhanced computed tomography: Little benefits of diffusion‑weighted imaging for lesion detection

Zhenshan Shi, Xiumei Li, Ruixiong You, Yueming Li, Xianying Zheng, Kamisha Ramen, Vikash Sahadeo Loosa, Dairong Cao, Qunlin Chen
Pages: 3117-3125
Published online on: 28 June 2018

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Article Open Access

Tubeimoside‑1 inhibits the proliferation and metastasis by promoting miR‑126‑5p expression in non‑small cell lung cancer cells

Hanbing Shi, Hongxia Bi, Xingyuan Sun, Haiying Dong, Yunfei Jiang, Haijun Mu, Wei Li, Guohua Liu, Ruizhi Gao, Jiang Su
Pages: 3126-3134
Published online on: 29 June 2018

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Article Open Access

Clinical significance of cytokeratin in the cervical lymph nodes of patients with mandibular gingival squamous cell carcinoma

Qingyun Duan, Mei Xu, Xiong Zhang, Muyun Jia, Rongtao Yuan, Min Gan
Pages: 3135-3139
Published online on: 21 June 2018

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Article Open Access

Expression of miR-30c and miR-29b in prostate cancer and its diagnostic significance

Chuanan Zhu, Xiumei Hou, Jiabin Zhu, Chunxiao Jiang, Wei Wei
Pages: 3140-3144
Published online on: 21 June 2018

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Article Open Access

A study on the biological function of heat shock factor 1 proteins in breast cancer

Xiaolan Wang, Dianlong Zhang, Mingqian Cao, Jinling Ba, Bin Wu, Tao Liu, Chen Nie
Pages: 3145-3149
Published online on: 28 June 2018

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Article Open Access

miR‑18a‑5p promotes cell invasion and migration of osteosarcoma by directly targeting IRF2

Chao Lu, Kan Peng, Hao Guo, Xiaoyu Ren, Shouye Hu, Yuanzhen Cai, Yan Han, Le Ma, Peng Xu
Pages: 3150-3156
Published online on: 27 June 2018

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Article Open Access

Radiofrequency ablation combined with esophageal stent in the treatment of malignant esophageal stenosis: A single-center prospective study

Yonggui Zhang, Mingwei Zhou, Lin Bai, Rongyan Han, Kang Lv, Zhe Wang
Pages: 3157-3161
Published online on: 28 June 2018

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Article

Anticancer effect of salidroside reduces viability through autophagy/PI3K/Akt and MMP‑9 signaling pathways in human bladder cancer cells

Tian Li, Kewei Xu, Yifan Liu
Pages: 3162-3168
Published online on: 18 June 2018

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Article

MicroRNA‑376a regulates cell proliferation and apoptosis by targeting forkhead box protein P2 in lymphoma

Shuna Yao, Yanyan Liu, Zhihua Yao, Yan Zhao, Haiying Wang, Yuanlin Xu, Jiuyang Zhang, Jing Li, Shujun Yang
Pages: 3169-3176
Published online on: 22 June 2018

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Article

Deoxypodophyllotoxin induces cell cycle arrest and apoptosis in human cholangiocarcinoma cells

Meifang Xiao, Xuegong Fan, Yongming Fu, Yujuan Zhou, Shaohui Liu, Shifang Peng
Pages: 3177-3182
Published online on: 18 June 2018

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Article

Potential biomarkers of HCC based on gene expression and DNA methylation profiles

Chao Meng, Xiaomin Shen, Wentao Jiang
Pages: 3183-3192
Published online on: 26 June 2018

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Article

Mitochondrial ROS activate interleukin‑1β expression in allergic rhinitis

Qiping Shi, Zhiwei Lei, Gui Cheng, Dehai Li, Qian Wang, Simin Luo, Hengwen Yang, Haiying Jia
Pages: 3193-3200
Published online on: 18 June 2018

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Article

The diagnostic value of PI‑RADS V1 and V2 using multiparametric MRI in transition zone prostate clinical cancer

Ximing Wang, Jie Bao, Xiaoxia Ping, Chunhong Hu, Jianquan Hou, Fenglin Dong, Lingchuan Guo
Pages: 3201-3206
Published online on: 28 June 2018

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Article

Scinderin‑knockdown inhibits proliferation and promotes apoptosis in human breast carcinoma cells

Wenjing Jian, Xiaoli Zhang, Jiguo Wang, Yunlong Liu, Chuting Hu, Xianming Wang, Renbin Liu
Pages: 3207-3214
Published online on: 21 June 2018

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Article

Value of systemic PET/CT in the diagnosis and differential diagnosis of aplastic anemia

Meilan Chen, Liyuan Lu, Juan Li, Bin Zhang, Junru Liu, Jingli Gu, Dong Zheng, Xiuzhen Tong, Hehua Wang
Pages: 3215-3222
Published online on: 28 June 2018

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Article

The impact of exogenous CO releasing molecule CORM‑2 on inflammation and signaling of orthotopic lung cancer

Li Shao, Congyang Liu, Shuhua Wang, Jiannan Liu, Li Wang, Liping Lv, Yong Zou
Pages: 3223-3230
Published online on: 26 June 2018

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Article

Identification of six serum antigens and autoantibodies for the detection of early stage epithelial ovarian carcinoma by bioinformatics analysis and liquid chip analysis

Yupeng Zou, Li Li
Pages: 3231-3240
Published online on: 26 June 2018

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Article

Anti‑Condyloma acuminata mechanism of microRNAs‑375 modulates HPV in cervical cancer cells via the UBE3A and IGF‑1R pathway

Shuying Wu, Hong Chen
Pages: 3241-3247
Published online on: 18 June 2018

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Article

Knockdown of lncRNA TP73‑AS1 inhibits gastric cancer cell proliferation and invasion via the WNT/β‑catenin signaling pathway

Yufeng Wang, Shuai Xiao, Bingyi Wang, Yang Li, Quanning Chen
Pages: 3248-3254
Published online on: 28 June 2018

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Article

Cell‑free culture conditioned medium elicits pancreatic β cell lineage‑specific epigenetic reprogramming in mice

Koichi Kawamoto, Tomofumi Ohashi, Masamitsu Konno, Naohiro Nishida, Jun Koseki, Hidetoshi Matsui, Daisuke Sakai, Toshihiro Kudo, Hidetoshi Eguchi, Taroh Satoh, Yuichiro Doki, Masaki Mori, Hideshi Ishii
Pages: 3255-3259
Published online on: 21 June 2018

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Article

Anti‑Müllerian hormone inhibits proliferation and induces apoptosis in epithelial ovarian cancer cells by regulating the cell cycle and decreasing the secretion of stem cell factor

Tiansong Zhang, Linhao Deng, Qian Xiong, Shujun Su, Jian Gu
Pages: 3260-3266
Published online on: 18 June 2018

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Article

Serum exosomal microRNA‑122 and microRNA‑21 as predictive biomarkers in transarterial chemoembolization‑treated hepatocellular carcinoma patients

Tomoyuki Suehiro, Hisamitsu Miyaaki, Yasuko Kanda, Hidetaka Shibata, Takuya Honda, Eisuke Ozawa, Satoshi Miuma, Naota Taura, Kazuhiko Nakao
Pages: 3267-3273
Published online on: 19 June 2018

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Article

Thymidylate synthase predicts poor response to pemetrexed chemotherapy in patients with advanced breast cancer

Fei Shan, Yu‑Lin Liu, Qiang Wang, Yan‑Long Shi
Pages: 3274-3280
Published online on: 15 June 2018

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Article

Optimized lymph node dissection range during progression of lower thoracic esophageal squamous cell carcinoma in the latest therapeutic surgical strategy: A retrospective analysis

Hiroki Harada, Kei Hosoda, Hiromitsu Moriya, Hiroaki Mieno, Akira Ema, Marie Washio, Yoshimasa Kosaka, Masahiko Watanabe, Keishi Yamashita
Pages: 3281-3289
Published online on: 27 June 2018

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Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis Corrigendum in /10.3892/ol.2026.15649

Jianfeng Xu, Lei Yang, Liang Dong
Pages: 3290-3296
Published online on: 26 June 2018

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Article

Anticancer effect of resibufogenin on gastric carcinoma cells through the phosphoinositide 3‑kinase/protein kinase B/glycogen synthase kinase 3β signaling pathway

Zhen Lu, Aman Xu, Xiao Yuan, Kaiwei Chen, Likun Wang, Tao Guo
Pages: 3297-3302
Published online on: 18 June 2018

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Article

Circulating plasma microRNAs in the detection of esophageal squamous cell carcinoma

Lu Zhang, Bing Dong, Pengfei Ren, Hua Ye, Jianxiang Shi, Jiejie Qin, Kaijuan Wang, Peng Wang, Jianying Zhang
Pages: 3303-3318
Published online on: 20 June 2018

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Article

Upregulation of miR‑375 inhibits human liver cancer cell growth by modulating cell proliferation and apoptosis via targeting ErbB2

Lina Li, Liping Jia, Yan Ding
Pages: 3319-3326
Published online on: 22 June 2018

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Article

The protective effect of puerarin on angiotensin II‑induced aortic aneurysm formation by the inhibition of NADPH oxidase activation and oxidative stress‑triggered AP‑1 signaling pathways

Jie Yue, Shunwu Chang, Zhanxiang Xiao, Youfei Qi, Jianxing He
Pages: 3327-3332
Published online on: 26 June 2018

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Article

Oridonin inhibits growth and induces apoptosis of human neurocytoma cells via the Wnt/β‑catenin pathway

Jingyan Liang, Weiguang Wang, Lifu Wei, Shan Gao, Yingge Wang
Pages: 3333-3340
Published online on: 18 June 2018

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Article

Arsenic trioxide and sorafenib combination therapy for human hepatocellular carcinoma functions via up‑regulation of TNF‑related apoptosis‑inducing ligand

Lingyan Wang, Zhihui Min, Xiangdong Wang, Mushuang Hu, Dongli Song, Zhenggang Ren, Yunfeng Cheng, Yanhong Wang
Pages: 3341-3350
Published online on: 18 June 2018

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Article

Oncostatin M treatment increases the responsiveness toward cisplatin‑based chemoradiotherapy in cervical cancer cells in a STAT3‑dependent manner

Russalina Stroeder, Barbara Walch‑Rückheim, Jil Fischbach, Ingolf Juhasz‑Böss, Christian Rübe, Erich‑Franz Solomayer, Sigrun Smola
Pages: 3351-3358
Published online on: 18 June 2018

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Article

MicroRNA‑2682‑3p inhibits osteosarcoma cell proliferation by targeting CCND2, MMP8 and Myd88

Fan Zhang, Yanjie Zhu, Guoxin Fan, Shuo Hu
Pages: 3359-3364
Published online on: 27 June 2018

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Article

Long non‑coding RNA H19 promotes the migration and invasion of colon cancer cells via MAPK signaling pathway

Weiwei Yang, Rajkumar Ezakiel Redpath, Chongyou Zhang, Ning Ning
Pages: 3365-3372
Published online on: 29 June 2018

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Article

Downregulation of BIRC5 inhibits the migration and invasion of esophageal cancer cells by interacting with the PI3K/Akt signaling pathway

Xiaobin Shang, Guoyan Liu, Yuefeng Zhang, Peng Tang, Hongdian Zhang, Hongjing Jiang, Zhentao Yu
Pages: 3373-3379
Published online on: 18 June 2018

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Article

Preliminary evaluation of the potential role of β‑elemene in reversing erlotinib‑resistant human NSCLC A549/ER cells

Lan Lin, Lianbin Li, Xiangqi Chen, Bangwei Zeng, Tingyan Lin
Pages: 3380-3388
Published online on: 18 June 2018

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Article

Carbon ion beam radioresistant rodent cells are sensitized to trifluorothymidine exposure

Sung‑Jae Baek, Katsutoshi Sato, Naohiro Nishida, Jun Koseki, Kazuhiko Hayashi, Koichi Kawamoto, Masamitsu Konno, Yuichiro Doki, Masaki Mori, Kazuhiko Ogawa, Hideshi Ishii
Pages: 3389-3393
Published online on: 21 June 2018

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Article

DNA double strand breaks induced by low dose mammography X‑rays in breast tissue: A pilot study

Julie Depuydt, Tanguy Viaene, Phillip Blondeel, Nathalie Roche, Rudy Van den Broecke, Hubert Thierens, Anne Vral
Pages: 3394-3400
Published online on: 26 June 2018

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Article

Association between the overexpression of PBOV1 and the prognosis of patients with hepatocellular carcinoma

Chengbiao Xue, Zibiao Zhong, Shaojun Ye, Yanfeng Wang, Qifa Ye
Pages: 3401-3407
Published online on: 25 June 2018

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Correction Open Access

[Erratum] BRCA1 homozygous unclassified variant in a patient with non‑Fanconi anemia: A case report

Davide Bondavalli, Francesca Malvestiti, Valeria Pensotti, Irene Feroce, Bernardo Bonanni
Pages: 3408-3408
Published online on: 25 June 2018

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Correction Open Access

[Corrigendum] Label‑free quantitative proteomic analysis identifies CTNNB1 as a direct target of FOXP3 in gastric cancer cells

Du‑Yi Pan, Xiao‑Qing Zeng, Gui‑Fen Ma, Jing Gao, Na Li, Qing Miao, Jing‑Jing Lian, Hu Zhou, Li‑Li Xu, Shi‑Yao Chen
Pages: 3409-3409
Published online on: 25 June 2018

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Review

Electrochemotherapy in head and neck cancer: A review of an emerging cancer treatment (Review)

Armando De Virgilio, Massimo Ralli, Lucia Longo, Patrizia Mancini, Giuseppe Attanasio, Francesca Atturo, Marco De Vincentiis, Antonio Greco
Pages: 3415-3423
Published online on: 12 July 2018

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Review

The role of lncRNAs in the development of endometrial carcinoma (Review)

Bi‑Lan Li, Xiao‑Ping Wan
Pages: 3424-3429
Published online on: 04 July 2018

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Article Open Access

Recurrence‑associated factors of laparoscopic adenomyomectomy for severely symptomatic adenomyoma

Wentao Yu, Guanyuan Liu, Chongdong Liu, Zhenyu Zhang
Pages: 3430-3438
Published online on: 05 July 2018

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Article Open Access

In vivo acquired sorafenib‑resistant patient‑derived tumor model displays alternative angiogenic pathways, multi‑drug resistance and chromosome instability

Gang Hu, Yixin Zhang, Kedong Ouyang, Fubo Xie, Houshun Fang, Xueyang Yang, Kunyan Liu, Zongyu Wang, Xuzhen Tang, Jibin Liu, Lei Yang, Zhenzhou Jiang, Weikang Tao, He Zhou, Luyong Zhang
Pages: 3439-3446
Published online on: 04 July 2018

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Article Open Access

Identification of genes that predict the biochemical recurrence of prostate cancer

Jianfeng Chu, Ning Li, Wentao Gai
Pages: 3447-3452
Published online on: 10 July 2018

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Article Open Access

Downregulation of ERBB3 decreases the proliferation, migration and invasion of cervical cancer cells though the interaction with MTK‑1

Jingyun Du, Shihua Zhou, Li Wang, Mulan Yu, Liyan Mei
Pages: 3453-3458
Published online on: 05 July 2018

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microRNA‑761 regulates glycogen synthase kinase 3β expression and promotes the proliferation and cell cycle of human gastric cancer cells

Xinfang Sun, Hongtao Hou, Ke Li, Mingming Zheng
Pages: 3459-3464
Published online on: 11 July 2018

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Article Open Access

Expression of V‑domain immunoglobulin suppressor of T cell activation is associated with the advanced stage and presence of lymph node metastasis in ovarian cancer

Hong Liao, Hongmei Zhu, Shanling Liu, He Wang
Pages: 3465-3472
Published online on: 02 July 2018

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Article Open Access

Expression of ELF5 in endometrial carcinoma tissues and its clinical significance

He Yang, Hongchao Yan
Pages: 3473-3480
Published online on: 05 July 2018

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Article Open Access

Downregulation of Dock1 and Elmo1 suppresses the migration and invasion of triple‑negative breast cancer epithelial cells through the RhoA/Rac1 pathway

Yueyang Liang, Shushu Wang, Yi Zhang
Pages: 3481-3488
Published online on: 04 July 2018

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Article Open Access

Dual targeting of survivin and X‑linked inhibitor of apoptosis protein suppresses the growth and promotes the apoptosis of gastric cancer HGC‑27 cells

Yanfeng Li, Wenbo Gao, Yan Ma, Guanyu Zhu, Fuhui Chen, Hongyan Qu
Pages: 3489-3498
Published online on: 05 July 2018

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Article Open Access

Ferritin level prospectively predicts hepatocarcinogenesis in patients with chronic hepatitis B virus infection

Zhenyuan Bian, Hie‑Won Hann, Zhong Ye, Chun Yin, Yang Wang, Wan Fang, Shaogui Wan, Chun Wang, Kaishan Tao
Pages: 3499-3508
Published online on: 06 July 2018

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Article Open Access

Autophagy inhibitor chloroquine induces apoptosis of cholangiocarcinoma cells via endoplasmic reticulum stress

Baoxing Jia, Yanan Xue, Xiaoyu Yan, Jiuling Li, Yao Wu, Rui Guo, Juanjuan Zhang, Lichao Zhang, Yaping Li, Yahui Liu, Liankun Sun
Pages: 3509-3516
Published online on: 11 July 2018

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Article Open Access

ARHGAP24 regulates cell ability and apoptosis ofcolorectal cancer cells via the regulation of P53

Suiliang Zhang, Liang Sui, Juhua Zhuang, Saifei He, Yanan Song, Ying Ye, Wei Xia
Pages: 3517-3524
Published online on: 04 July 2018

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Article Open Access

miR-486-5p inhibits cell proliferation and invasion through repressing GAB2 in non-small cell lung cancer

Sunfeng Yu, Shuang Geng, Yi Hu
Pages: 3525-3530
Published online on: 29 June 2018

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Article Open Access

Retrospective study on recovery of 521 gastrointestinal tumor patients after laparoscopic surgery

Jiakun Shi, Shengjie Li, Yujie Wang, Lei Zheng
Pages: 3531-3536
Published online on: 04 July 2018

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Article

Upregulating MMP‑1 in carcinoma‑associated fibroblasts reduces the efficacy of Taxotere on breast cancer synergized by Collagen IV

Qingyu Cui, Bixiao Wang, Kaifu Li, Haichen Sun, Tao Hai, Yan Zhang, Hua Kang
Pages: 3537-3544
Published online on: 05 July 2018

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Article Open Access

Homoisoflavanone‑1 isolated from Polygonatum odoratum arrests the cell cycle and induces apoptosis in A549 cells

Deli Ning, Ming Jin, Tao Xv, Jikai Sun, Min Li
Pages: 3545-3554
Published online on: 05 July 2018

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Case Report Open Access

Abscopal effect of radiation on lymph node metastasis in esophageal carcinoma: A case report and literature review

Xiangfei Zhao, Jingbo Kang, Rugang Zhao
Pages: 3555-3560
Published online on: 05 July 2018

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Article Open Access

miR‑329 inhibits papillary thyroid cancer progression via direct targeting WNT1

Liang Wu, Fulai Pei, Xiaojuan Men, Kai Wang, Deliang Ma
Pages: 3561-3568
Published online on: 06 July 2018

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Article Open Access

Ailanthone induces autophagic and apoptotic cell death in human promyelocytic leukemia HL‑60 cells

Cheng Wei, Chuanrong Chen, Yuxin Cheng, Lin Zhu, Yu Wang, Can Luo, Yang He, Zhiming Yang, Zhaoning Ji
Pages: 3569-3576
Published online on: 06 July 2018

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Article Open Access

Exopolysaccharides produced by Lactobacillus strains suppress HT‑29 cell growth via induction of G0/G1 cell cycle arrest and apoptosis

Wei Di, Lanwei Zhang, Huaxi Yi, Xue Han, Yingchun Zhang, Liang Xin
Pages: 3577-3586
Published online on: 11 July 2018

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miR-329 regulates the sensitivity of 5-FU in chemotherapy of colorectal cancer by targeting E2F1

Jie Yin, Xiping Shen, Mei Li, Fangying Ni, Li Xu, Hua Lu
Pages: 3587-3592
Published online on: 11 July 2018

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Prognostic importance of bile duct invasion in surgical resection with curative intent for hepatocellular carcinoma using PSM analysis

Xinwei Yang, Zhiquan Qiu, Rongzhen Ran, Longjiu Cui, Xiangji Luo, Mengchao Wu, Wei‑Feng Tan, Xiaoqing Jiang
Pages: 3593-3602
Published online on: 10 July 2018

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High PKM2 expression is independently correlated with decreased overall survival in hepatocellular carcinoma

Dong‑Hui Lu, Wen‑Wen Lv, Wen‑Xing Li, Yue‑Dong Gao
Pages: 3603-3610
Published online on: 06 July 2018

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Article Open Access

Error analysis of applicator position for combined internal/external radiation therapy in cervical cancer

Wei Ying, Li Liang, Yu Wang, Guo-Hai Qi
Pages: 3611-3613
Published online on: 02 July 2018

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Article Open Access

Protective effect and mechanism of rat recombinant S100 calcium‑binding protein A4 on oxidative stress injury of rat vascular endothelial cells

Xiangyan Meng, Xiujie Gao, Zhiqing Zhang, Xuesi Zhou, Lei Wu, Miaomiao Yang, Kun Wang, Hanlin Ren, Bei Sun, Tianhui Wang
Pages: 3614-3622
Published online on: 11 July 2018

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PET/CT imaging analysis of recurrent sites and patterns of spread following modified radical surgery (type B) for stage Ib‑IIa cervical cancer

Shuxia Cheng, Yanmei Li, Mingchuan Zhang, Tingting Tong
Pages: 3623-3627
Published online on: 04 July 2018

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Article Open Access

Betulinic acid exerts potent antitumor effects on paclitaxel‑resistant human lung carcinoma cells (H460) via G2/M phase cell cycle arrest and induction of mitochondrial apoptosis

Xiao‑Kai Zhan, Jun‑Ling Li, Sen Zhang, Pu‑Yuan Xing, Meng‑Fan Xia
Pages: 3628-3634
Published online on: 06 July 2018

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Article Open Access

DNM1L, a key prognostic predictor for gastric adenocarcinoma, is involved in cell proliferation, invasion, and apoptosis

Xiao‑Wu Xu, Xiao‑Min Yang, Wei‑Jia Zhao, Lei Zhou, De‑Chun Li, Yi‑Hu Zheng
Pages: 3635-3641
Published online on: 11 July 2018

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Identification and verification of differentially expressed microRNAs and their target genes for the diagnosis of esophageal cancer

Xiaoyue Cai, Xiwen Yang, Changjuan Jin, Lei Li, Qing Cui, Yijun Guo, Yun Dong, Xiaohua Yang, Lili Guo, Ming Zhang
Pages: 3642-3650
Published online on: 04 July 2018

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Itraconazole inhibits the proliferation of gastric cancer cells in vitro and improves patient survival

Ke Lan, Ron Yan, Kun Zhu, Wenhan Li, Zisen Xu, Chengxue Dang, Kang Li
Pages: 3651-3657
Published online on: 04 July 2018

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Downregulation of trefoil factor‑3 expression in the rectum is associated with the development of ulcerative colitis‑associated cancer

Satoru Kondo, Toshimitsu Araki, Yuji Toiyama, Koji Tanaka, Mikio Kawamura, Yoshinaga Okugawa, Yoshiki Okita, Susumu Saigusa, Yasuhiro Inoue, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
Pages: 3658-3664
Published online on: 10 July 2018

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Prognostic impact of SET domain‑containing protein 8 and protein arginine methyltransferase 5 in patients with hepatocellular carcinoma following curative resection

Zhifei Lin, Huliang Jia, Liang Hong, Yahui Zheng, Weiqin Shao, Xudong Ren, Wenwei Zhu, Lu Lu, Ming Lu, Jubo Zhang, Jinhong Chen
Pages: 3665-3673
Published online on: 05 July 2018

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Article Open Access

Cetuximab retreatment in patients with metastatic colorectal cancer who exhibited a clinical benefit in response to prior cetuximab: A retrospective study

Hiroaki Tanioka, Motoi Asano, Ryousuke Yoshida, Naohisa Waki, Futoshi Uno, Masahiro Ishizaki, Kazuki Yamashita, Yuki Morishita, Takeshi Nagasaka
Pages: 3674-3680
Published online on: 11 July 2018

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Article Open Access

Decreased CRHBP expression is predictive of poor prognosis in patients with hepatocellular carcinoma

Hai‑Bing Xia, Hui‑Ju Wang, Luo‑Qin Fu, Shi‑Bing Wang, Li Li, Guo‑Qing Ru, Xiang‑Lei He, Xiang‑Min Tong, Xiao‑Zhou Mou, Dong‑Sheng Huang
Pages: 3681-3689
Published online on: 04 July 2018

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Article Open Access

Comparative analysis of tumor‑associated vascular changes following TACE alone or in combination with sorafenib treatment in HCC: A retrospective study

Ligang Chen, Yifei Zheng, Hongjian Zhang, Heng Pan, Qiusong Liu, Xu Zhou, Wei Wei, Yun Liu, Maochuan Zhen, Jinling Wang, Jianyin Zhou, Yilin Zhao
Pages: 3690-3698
Published online on: 02 July 2018

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Association between AKT rs2494752 single nucleotide polymorphism and the risk of metastasis in hepatocellular carcinoma

Zhaohui Wang, Huiling Fu, Wei Li
Pages: 3699-3705
Published online on: 02 July 2018

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Article Open Access

si‑TP73‑AS1 suppressed proliferation and increased the chemotherapeutic response of GC cells to cisplatin

Jianjun Peng
Pages: 3706-3714
Published online on: 10 July 2018

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Article Open Access

Preliminary screening and analysis of metastasis‑related lncRNA and co‑expressed papillary thyroid carcinoma mRNA

Ming‑Hua Ge, Lie‑Hao Jiang, Qing‑Liang Wen, Zhuo Tan, Chao Chen, Chuan‑Ming Zheng, Xin Zhu, Jia‑Wen Chen, Zi‑Yu Zhu, Xiu‑Jun Cai
Pages: 3715-3725
Published online on: 05 July 2018

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Article Open Access

Circulating HER‑2 mRNA in the peripheral blood as a potential diagnostic and prognostic biomarker in females with breast cancer

Yanlin Wu, Qiping Meng, Zhixue Yang, Lili Shi, Rongkuan Hu, Peizhuo Zhang, Jinrong Wei, Jie Ren, Bingjing Leng, Dong Xu, Guo‑Qin Jiang
Pages: 3726-3734
Published online on: 05 July 2018

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Article Open Access

LncRNAs KB‑1836B5, LINC00566 and FAM27L are associated with the survival time of patients with ovarian cancer

Huijian Li, Mi Gong, Min Zhao, Xinru Wang, Wenjun Cheng, Yankai Xia
Pages: 3735-3745
Published online on: 12 July 2018

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Article Open Access

Prognostic value of heterogeneous ribonucleoprotein A1 expression and inflammatory indicators for patients with surgically resected hepatocellular carcinoma: Perspectives from a high occurrence area of hepatocellular carcinoma in China Erratum in /10.3892/ol.2018.9580

Ruisheng Ke, Lizhi Lv, Jiayan Li, Xiaojin Zhang, Fang Yang, Kun Zhang, Yi Jiang
Pages: 3746-3756
Published online on: 04 July 2018

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[Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer

Senthil Rajappa, Ashish Joshi, Dinesh C. Doval, Ullas Batra, Rejiv Rajendranath, Avinash Deo, Ghanshyam Biswas, Peush Bajpai, T. V.S. Tilak, Sriram Kane, Kishore Kumar, Manish Kumar, Avinash D. Talele, Prakash Devde, Ashutosh Gupta, Nisarg Joshi, Jaykumar Sejpal, Deepak Bunger, Mujtaba Khan
Pages: 3757-3769
Published online on: 02 July 2018

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Article Open Access

Diagnostic accuracy of the UBC® Rapid Test for bladder cancer: A meta‑analysis

Pei Lu, Jianchun Cui, Keliang Chen, Qiang Lu, Jiexiu Zhang, Jun Tao, Zhijian Han, Wei Zhang, Rijin Song, Min Gu
Pages: 3770-3778
Published online on: 05 July 2018

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Article Open Access

Mechanism of the enhancing effects of miR‑93 on resistance of breast cancer MCF‑7 cells to adriamycin

Qian Wang, Chunying Su, Jiantao Li, Changsheng Wei
Pages: 3779-3783
Published online on: 29 June 2018

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Article Open Access

Endoglin‑targeted contrast‑enhanced ultrasound imaging in hepatoblastoma xenografts

Rong Shan, Bei Wang, Aiguang Wang, Zongguo Sun, Fengyun Dong, Ju Liu, Hongjun Sun
Pages: 3784-3790
Published online on: 04 July 2018

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Article Open Access

Expression of KIAA1456 in lung cancer tissue and its effects on proliferation, migration and invasion of lung cancer cells

Shuling Wang, Xiangqun Liu, Jianan Huang, Ying Zhang, Chunli Sang, Tao Li, Jieqing Yuan
Pages: 3791-3795
Published online on: 10 July 2018

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Article Open Access

Overexpression of SMARCA2 or CAMK2D is associated with cisplatin resistance in human epithelial ovarian cancer

Xiaoli Xu, Zhiguo Zheng, Lanlan Jia, Shasha Suo, Bowen Liu, Tianning Shao, Qinqing Tu, Yuejin Hua, Hong Xu
Pages: 3796-3804
Published online on: 10 July 2018

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Article Open Access

Clinical significance of decreased programmed cell death 4 expression in patients with giant cell tumors of the bone

Fei Gao, Wei Zhang, Lingling Ding, Miaoqing Zhao, Zhe Ma, Shanying Huang
Pages: 3805-3811
Published online on: 05 July 2018

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Article Open Access

Dual effects of arsenic trioxide on tumor cells and the potential underlying mechanisms

Xiao Zhang, Dahai Yu, Huaize Geng, Fengmei Li, Lin Lv, Lei Zhao, Caichuan Yan, Baoxin Li
Pages: 3812-3820
Published online on: 05 July 2018

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A study on the biological function of heat shock factor 1 proteins in breast cancer

Xiaolan Wang, Dianlong Zhang, Mingqian Cao, Jinling Ba, Bin Wu, Tao Liu, Chen Nie
Pages: 3821-3825
Published online on: 02 July 2018

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Article Open Access

Bufalin induced apoptosis of bladder carcinoma cells through the inactivation of Na+K+‑ATPase

Houbao Huang, Wei Zhang
Pages: 3826-3832
Published online on: 12 July 2018

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Article Open Access

Genetic variations in the SULF1 gene alter the risk of cervical cancer and precancerous lesions

Efthimios Dardiotis, Vasileios Siokas, Antonios Garas, Evangelos Paraskevaidis, Maria Kyrgiou, Georgia Xiromerisiou, Efthimios Deligeoroglou, Georgios Galazios, Emmanuel N. Kontomanolis, Demetrios A. Spandidos, Aristidis Tsatsakis, Alexandros Daponte
Pages: 3833-3841
Published online on: 06 July 2018

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Article Open Access

CREB1, a direct target of miR-122, promotes cell proliferation and invasion in bladder cancer

Lihua Guo, Min Yin, Yixuan Wang
Pages: 3842-3848
Published online on: 10 July 2018

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Article Open Access

Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin increases the activation of aryl hydrocarbon receptor and is associated with the aggressiveness of osteosarcoma MG-63 osteoblast-like cells

Shih-Chieh Yang, Chin-Hsien Wu, Yuan-Kun Tu, Shin-Yu Huang, Pai-Chien Chou
Pages: 3849-3857
Published online on: 06 July 2018

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Bleomycin inhibits proliferation and induces apoptosis in TPC‑1 cells through reversing M2‑macrophages polarization

Hongwei Liu, Huilei Dong, Li Jiang, Zhendong Li, Xiande Ma
Pages: 3858-3866
Published online on: 06 July 2018

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Article Open Access

Bufalin suppresses the proliferation and metastasis of renal cell carcinoma by inhibiting the PI3K/Akt/mTOR signaling pathway

Jinlin Xie, Wenfeng Lin, Linglong Huang, Naijin Xu, Abai Xu, Binshen Chen, Masami Watanabe, Chunxiao Liu, Peng Huang
Pages: 3867-3873
Published online on: 10 July 2018

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Article

Suppression of Hiwi inhibits the growth and epithelial‑mesenchymal transition of cervical cancer cells

Guangjun Pei, Baojian Li, Anjun Ma
Pages: 3874-3880
Published online on: 02 July 2018

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Article

Irreversible electroporation of malignant liver tumors: Effect on laboratory values

Mohammed Alnaggar, Ammar M. Qaid, Jibing Chen, Lizhi Niu, Kecheng Xu
Pages: 3881-3888
Published online on: 02 July 2018

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Case Report

Low‑grade myofibroblastic sarcoma arising in the tip of the tongue with intravascular invasion: A case report

Yurie Mikami, Shinsuke Fujii, Ken‑Ichi Kohashi, Yuichi Yamada, Masafumi Moriyama, Shintaro Kawano, Seiji Nakamura, Yoshinao Oda, Tamotsu Kiyoshima
Pages: 3889-3894
Published online on: 10 July 2018

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Article Open Access

Neoangiogenesis of gastric submucosa‑invasive adenocarcinoma

Hanae Sasaki, Satoko Morohashi, Takahito Toba, Hiroko Seino, Tadashi Yoshizawa, Hideaki Hirai, Toshihiro Haga, Yunyan Wu, Hiroshi Kijima
Pages: 3895-3900
Published online on: 10 July 2018

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Article

Astragaloside attenuates the progression of prostate cancer cells through endoplasmic reticulum stress pathways

Bo Tan, Renfeng Jia, Gang Wang, Jinhui Yang
Pages: 3901-3906
Published online on: 04 July 2018

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Article

LncRNA ATB promotes the proliferation and metastasis of lung cancer via activation of the p38 signaling pathway

Lei Wei, Tao Wu, Ping He, Jun‑Lei Zhang, Wei Wu
Pages: 3907-3912
Published online on: 10 July 2018

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Case Report

Identification of a novel breast cancer‑causing mutation in the BRCA1 gene by targeted next generation sequencing: A case report

Yanyan Wang, Da Jiang, Qiang Zhao, Hui Huang, Xue Zhang, Yanzhi Cui, Jiayin Liu, Jing Wu, Keke Lin, Weixi Chen, Jiale Xiang, Hui Jin, Zhiyu Peng, Santasree Banerjee
Pages: 3913-3916
Published online on: 12 July 2018

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Article

Distribution of circulating follicular helper T cells and expression of interleukin‑21 and chemokine C‑X‑C ligand 13 in gastric cancer

Xinying Meng, Xinjuan Yu, Quanjiang Dong, Xiaona Xu, Jinghua Li, Qianqian Xu, Jian Ma, Changhong Zhou
Pages: 3917-3922
Published online on: 10 July 2018

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Article

HIV positivity may not have a negative impact on survival in Epstein‑Barr virus‑positive Hodgkin lymphoma: A Japanese nationwide retrospective survey

Mihoko Yotsumoto, Yoshikazu Ito, Shotaro Hagiwara, Yasuhito Terui, Hirokazu Nagai, Yasunori Ota, Atsushi Ajisawa, Tomoko Uehira, Junko Tanuma, Kazuma Ohyashiki, Seiji Okada
Pages: 3923-3928
Published online on: 11 July 2018

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Article

Triptolide induces protective autophagy and apoptosis in human cervical cancer cells by downregulating Akt/mTOR activation

Guangyi Qin, Ping Li, Zhuowei Xue
Pages: 3929-3934
Published online on: 04 July 2018

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Article

LncRNA‑ECM is overexpressed in esophageal squamous cell carcinoma and promotes tumor metastasis

Juan Yao, Xiaozhou Shen, Hongzhi Li, Jie Xu, Shanshan Shao, Jun‑Xing Huang, Mei Lin
Pages: 3935-3942
Published online on: 11 July 2018

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Article Open Access

Mn12Ac inhibits the migration, invasion and epithelial‑mesenchymal transition of lung cancer cells by downregulating the Wnt/β‑catenin and PI3K/AKT signaling pathways

Zihao Chen, Jiangbo He, Xiqian Xing, Ping Li, Wei Zhang, Zhuxiu Tong, Xiaojie Jing, Licheng Li, Dian Liu, Qiong Wu, Hongping Ju
Pages: 3943-3948
Published online on: 11 July 2018

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Article

Role of YAP in lung cancer resistance to cisplatin

Juan Song, Li‑Xia Xie, Xin‑Yi Zhang, Ping Hu, Mei‑Fang Long, Fang Xiong, Juan Huang, Xiao‑Qun Ye
Pages: 3949-3954
Published online on: 12 July 2018

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Function of GCN5 in the TGF‑β1‑induced epithelial‑to‑mesenchymal transition in breast cancer

Liming Zhao, Aixia Pang, Yunchun Li
Pages: 3955-3963
Published online on: 11 July 2018

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Article

Upregulation of gastric adenocarcinoma predictive long intergenic non‑coding RNA promotes progression and predicts poor prognosis in perihilar cholangiocarcinoma

Xin‑Ping Wang, Jing Song, Gui‑Ting Liu, Jian‑Jun Wang, Hai‑Feng Guo
Pages: 3964-3972
Published online on: 11 July 2018

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Case Report

Squamous cell carcinoma of the spleen: A case report

Zhou Jiang, Fang Ma, Xianling Liu
Pages: 3973-3975
Published online on: 06 July 2018

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Article

Targeting CXC motif chemokine receptor 4 inhibits the proliferation, migration and angiogenesis of lung cancer cells

Wei He, Tong Yang, Xin‑Hua Gong, Ru‑Zhai Qin, Xiao‑Dong Zhang, Wen‑Dan Liu
Pages: 3976-3982
Published online on: 04 July 2018

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Article

Silencing of uPAR via RNA interference inhibits invasion and migration of oral tongue squamous cell carcinoma

Xuexiang Gao, Qi Guo, Shuo Wang, Cen Gao, Jian Chen, Li Zhang, Yuan Zhao, Jing Wang
Pages: 3983-3991
Published online on: 06 July 2018

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Article

Dissecting the expression landscape of mitochondrial genes in lung squamous cell carcinoma and lung adenocarcinoma

Nan Li, Jing Zhao, Yibing Ma, Bhaskar Roy, Ren Liu, Karsten Kristiansen, Qiang Gao
Pages: 3992-4000
Published online on: 10 July 2018

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Article

The diagnostic and prognostic value of plasma microRNA‑125b‑5p in patients with multiple myeloma

Yanxia Jiang, Yajing Luan, Hong Chang, Guoan Chen
Pages: 4001-4007
Published online on: 11 July 2018

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Article

Effect of As2O3 on colorectal CSCs stained with ALDH1 in primary cell culture in vitro

Ke Ning, Wenlong Ning, Xiaoting Ning, Xueyan Wang, Fei Zhou
Pages: 4008-4012
Published online on: 10 July 2018

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Article

HMGN5 promotes proliferation and invasion via the activation of Wnt/β-catenin signaling pathway in pancreatic ductal adenocarcinoma

Jianwen Zhao, Yong Wang, Xinglong Wu
Pages: 4013-4019
Published online on: 05 July 2018

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Article

MicroRNA‑96 expression induced by low‑dose cisplatin or doxorubicin regulates chemosensitivity, cell death and proliferation in gastric cancer SGC7901 cells by targeting FOXO1

Chunhui Lang, Miao Xu, Ziyi Zhao, Jinyao Chen, Lishi Zhang
Pages: 4020-4026
Published online on: 11 July 2018

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Article

Establishment of an miR‑137‑knockout cell model using CRISPR/Cas9 genome editing

Wei Chen, Qi Li, Jingjie Du, Xiaodi Li, Songshan Jiang, Yuanli He
Pages: 4027-4032
Published online on: 06 July 2018

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Article

Combined effects of octreotide and cisplatin on the proliferation of side population cells from anaplastic thyroid cancer cell lines

Zhilan Li, Xiudi Jiang, Peihong Chen, Xuebing Wu, Aihua Duan, Yiyu Qin
Pages: 4033-4042
Published online on: 10 July 2018

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Case Report

Chronic active hepatitis induced by Pazopanib mimicking hypervascular liver metastases in a patient with recurrent soft tissue sarcoma: A case report

Ana Ezponda, Ignacio González De La Huebra, Marta Calvo, Miguel Ángel Idoate, Isabel Vivas
Pages: 4043-4048
Published online on: 10 July 2018

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Article

Optimal body mass index cut‑point for predicting recurrence‑free survival in patients with non‑muscle‑invasive urothelial carcinoma of bladder

Satoru Yonekura, Fumihito Terauchi, Kenji Hoshi, Takehiko Yamaguchi, Shigeo Kawai
Pages: 4049-4056
Published online on: 04 July 2018

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Article

Ulinastatin protects the lungs of COPD rats through the HMGB1/TLR4 signaling pathway

Wei Liu, Zhiguang Liu, Weidong Zhang, Shaoxi Cai
Pages: 4057-4063
Published online on: 11 July 2018

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Article

Proteins involved in cutaneous basal cell carcinoma development

Magdalena Ciążyńska, Igor A. Bednarski, Karolina Wódz, Paweł Kolano, Joanna Narbutt, Michał Sobjanek, Anna Woźniacka, Aleksandra Lesiak
Pages: 4064-4072
Published online on: 11 July 2018

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Article

PARP9 is overexpressed in human breast cancer and promotes cancer cell migration

Xinghong Tang, Hongying Zhang, Yan Long, Hui Hua, Yangfu Jiang, Jing Jing
Pages: 4073-4077
Published online on: 11 July 2018

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Article

Circular RNA as a biomarker for cancer: A systematic meta‑analysis

Yulong Li, Xiaoli Zeng, Jianxun He, Yuan Gui, Song Zhao, Hua Chen, Qi Sun, Nan Jia, Hui Yuan
Pages: 4078-4084
Published online on: 11 July 2018

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Case Report

Concurrent palliative external radiotherapy with sorafenib or doxorubicin for bulky differentiated thyroid carcinoma: A case report

Karen S. Cortés‑Mateus, Katarzyna Holub, Fabricio Racca, Juan José Grau, Jaume Capdevila
Pages: 4085-4089
Published online on: 04 July 2018

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October-2026 Volume 32 Issue 4

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SCImago Journal Rank (SJR): 0.663

Article Open Access

Efficacy and safety of rituximab in the treatment of primary central nervous system lymphoma: A meta‑analysis and systematic review of 1,388 patients

Lichaoyue Sun, Wenshu Li, Wei Chen, Chunxing Li, Zhao Ren, Qing Xie, Dongxiao Wang
Article Number: 488
Published online on: 02 September 2026

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Psychological stress and tumor progression: Molecular mechanisms and therapeutic implications (Review)

Yifei Zhang, Yajun Kong, Shuanbao Zhao
Article Number: 487
Published online on: 02 September 2026

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Development and evaluation of clinical models based on ultrasound, serum CA153 and molecular subtype in predicting the efficacy of neoadjuvant chemotherapy in breast cancer

Ming-Yue Du, Shu-E Zeng
Article Number: 486
Published online on: 02 September 2026

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Clinical utility of circulating tumor‑derived endothelial cells in lung cancer detection and prognosis prediction

Xiang Li, Jun Yang, Bin Chen, Ziyu Zhang, Jiangman Zhao, Mengxin Zhao, Zhimou Wang
Article Number: 485
Published online on: 02 September 2026

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Construction of a new predictive model in head and neck squamous cell carcinoma based on the investigation of extracellular matrix‑associated genes

Liangqian Tu, Yiyin Qiu, Handan Zheng, Bixin Fang, Ming Chen
Article Number: 484
Published online on: 02 September 2026

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Special Issue

Inhibition or induction of gastrointestinal tumors by ferroptosis and intervention by herbal extracts (Review)

Defei Yin, Qinghua Li, Junwei Liang, Xiaoyan Yan, Dajuan Sun
Article Number: 483
Published online on: 02 September 2026

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[Expression of Concern] Demethylation of microRNA-142 induced by demethylation agents plays a suppressive role in osteosarcoma cells

Muliang Ding, Jianzhong Hu, Jiangdong Ni, Zhonghui Zheng, Deye Song, Junjie Wang
Article Number: 482
Published online on: 01 September 2026

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CCT2 defines a highly cisplatin‑resistant and poor‑prognosis subtype of lung adenocarcinoma

Huafang Mao, Chao Su, Xiaoliang Han, Guoxia Wang
Article Number: 481
Published online on: 28 August 2026

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[Expression of Concern] Simvastatin potentiates doxorubicin activity against MCF‑7 breast cancer cells

Benjaporn Buranrat, Wanwisa Suwannaloet, Jarinyaporn Naowaboot
Article Number: 480
Published online on: 27 August 2026

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Characterization of ZIC5 expression in esophageal squamous cell carcinoma and its association with patient survival

Bo Yang, Baige Wang, Haiquan Deng, Yong Luo, Shenghao Wu, Huaxin Yin, Hongdian Zhang, Yuncheng Zhang, Zhen Zhang
Article Number: 479
Published online on: 26 August 2026

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Microbiome‑based diagnostic biomarkers in pancreatic ductal adenocarcinoma: Current evidence and translational challenges (Review)

Huiya Jin, Hui Sun, Jing Yang
Article Number: 478
Published online on: 26 August 2026

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[Corrigendum] Long non-coding RNA CCAT2 functions as an oncogene in hepatocellular carcinoma, regulating cellular proliferation, migration and apoptosis

Ning Zhou, Zhongzhou Si, Ting Li, Guangshun Chen, Zhongqiang Zhang, Haizhi Qi
Article Number: 477
Published online on: 26 August 2026

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Efficacy and safety of ICI‑based triple combination therapy for gene‑negative advanced lung adenocarcinoma

Diwei Mo, Huan Chen, Zhihong Zhu, Jinghua Yu, Xia Yang, Yiyu Lu, Keng Wang, Guifeng Xu, Luwen Lei, Xingxi Pan
Article Number: 476
Published online on: 25 August 2026

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[Corrigendum] Angiotensin II type 2 receptor‑interacting protein 3a suppresses proliferation, migration and invasion in tongue squamous cell carcinoma via the extracellular signal‑regulated kinase‑Snai2 pathway

Tingting Zhao, Qianting He, Zhonghua Liu, Xueqiang Ding, Xiaofeng Zhou, Anxun Wang
Article Number: 475
Published online on: 24 August 2026

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Pazopanib treatment for primary cardiovascular sarcoma: A retrospective observational study and literature review

Shintaro Yamanaka, Yoshihiro Yakushijin, Shinji Hasebe, Shoichiro Yamamoto, Tomomi Fujii, Riko Kitazawa, Taketsugu Fujibuchi, Teruki Kidani, Masaki Maruta
Article Number: 474
Published online on: 21 August 2026

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Primary cutaneous angiosarcoma of the scalp initially misdiagnosed as cellulitis in a 95‑year‑old Asian man: A case report

Baopeng Qi, Qianru Li, Yuan Gao, Yuanyu Tang, Yang Yu
Article Number: 473
Published online on: 21 August 2026

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Colorectal cancer and tumor vaccines (Review)

Jianshuang Ma, Congming Xiang, Dong Xia
Article Number: 472
Published online on: 21 August 2026

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Pre‑radiotherapy modified prognostic nutritional index predicts acute radiation enteritis in patients with cervical cancer undergoing radiotherapy: A retrospective study

Yani Zou, Rui Huang, Wenqiang Qin, Chunqiu Wu, Wei Zhang
Article Number: 471
Published online on: 21 August 2026

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[Corrigendum] MicroRNA‑101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A

Lumin Wang, Jiayi Yao, Hongfei Sun, Kang He, Dongdong Tong, Tusheng Song, Chen Huang
Article Number: 470
Published online on: 20 August 2026

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Boost delivery in hypofractionated breast cancer radiotherapy: A registry‑based analysis of treatment patterns and survival

Karoline Elisabeth Horry, Dirk Vordermark, Daniel Medenwald, Jörg Andreas Müller
Article Number: 469
Published online on: 18 August 2026

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Effect of perioperative nutritional status, inflammatory response and postoperative chemotherapy on survival after gastrectomy for advanced gastric cancer

Yoshinori Fujiwara, Shunji Endo, Masaharu Higashida, Masaaki Hori, Yoko Endo, Ryoko Makieda, Akihide Fujii, Miyoko Kobayashi, Kazuhiko Yoshimatsu, Tomio Ueno
Article Number: 468
Published online on: 18 August 2026

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[Retracted] miR‑185‑5p targets ROCK2 and inhibits cell migration and invasion of hepatocellular carcinoma

Yuexiang Niu, Gongen Tang
Article Number: 467
Published online on: 17 August 2026

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Article

OLFML2A expression in acute myeloid leukemia, with exploratory findings in acute lymphoblastic leukemia: Prognostic significance and re‑analysis of public single‑cell transcriptomic data

Xuan Lu, Jinlian Li, Xinru Zhao, Wanchuan Zhuang, Xingxing Chai
Article Number: 466
Published online on: 17 August 2026

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Identifying an appropriate endogenous control for real‑time PCR of microRNAs in colorectal liver metastases: A comparison of 18s rRNA and small nuclear RNA RNU6B

Clemens Franz, Sibylle Hartmann, Alexis Ulrich, Georgios Polychronidis, Christoph Kahlert, Fee Klupp, Mohammed Al‑Saeedi
Article Number: 465
Published online on: 17 August 2026

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Analysis of DNA methylation markers for diagnosing cervical precancer and cancer: A single‑center cross‑sectional study

Xue Chen, Jialing Li, Li Tian, Xinshu Li, Jingwen Guo, Liling He, Shulian Mao, Xitang Yang, Hua Guo
Article Number: 464
Published online on: 17 August 2026

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Flavokawain A inhibits high glucose‑induced malignant progression of lung cancer cells by suppressing PRMT5‑mediated PTEN neddylation and nuclear translocation

Lei Zheng, Juan Li, Chao Song, Leping Shi, Qian Zhou, Yuyao Guan
Article Number: 463
Published online on: 14 August 2026

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Metabolic heterogeneity and functional diversity of cancer-associated fibroblasts in gastric cancer (Review)

Qilu Fang, Neng Lv, Shuwei Yu, Jia Wang, Wenxiu Xin
Article Number: 462
Published online on: 14 August 2026

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Preoperative CA125 and metabolic factors associated with high‑risk pathology in endometrial cancer

Yinuo Wang, Yueqi Yan, Wen Sun, Yiting Gao, Bingli Qi, Xia Li, Shouze Liu, Shikai Liu
Article Number: 461
Published online on: 14 August 2026

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EGR1 regulates IGF‑1‑stimulated pancreatic cancer cell invasion by increasing IL‑11 expression 

Yena Choi, Euitaek Jung, Junekyu Han, Soon Young Shin
Article Number: 460
Published online on: 13 August 2026

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Claudin‑18.2: Molecular mechanisms to clinical translation in solid tumors (Review)

Minjie Zhang, Dawei Wu, Yu Tang, Ning Li, Xinhua Yan
Article Number: 459
Published online on: 12 August 2026

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Case Report Open Access

Probable cavernous sinus‑adjacent meningeal metastasis from esophageal squamous cell carcinoma: A case report

Heng Di Zhang, Bin He, Jing Jing Peng, Ting Yu, Fang Yuan Kong, Ling Zhang
Article Number: 458
Published online on: 12 August 2026

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Immunotherapy combined with anti‑angiogenic therapy, radiotherapy and chemotherapy for the treatment of giant pelvic osteosarcoma: A case report and literature review

Qingying Yan, Jiewen Yang, Yunxia Liu, Miao Cheng, Zhen Wang, Jialu Chen, Yefeng Xu
Article Number: 457
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Obesity accelerates murine gastric cancer growth by modulating the Sirt1/YAP pathway

Hai-Jun Li, Jun-Ke Fu, Xiang-Ming Che, Lin Fan, Yong Zhang, E Bai
Article Number: 456
Published online on: 12 August 2026

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Tumor suppressor syntaxin binding protein 1 regulates alternative splicing of DNA repair genes related to radiation sensitivity in breast cancer cells

Meng Zhang, Xiaoxue Zhang, Qian Rou, Ying Liu, Ailifeire Abudujiapaer, Minghui Li, Huaixiong Wang, Fang Cheng
Article Number: 455
Published online on: 12 August 2026

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Retraction Open Access

[Retracted] 2’,4’‑dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC‑3 human prostate cancer cell growth by induction of apoptosis 

Yuqing Sheng, Mingchang Zou, Yan Wang, Qiheng Li
Article Number: 454
Published online on: 11 August 2026

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Case Report Open Access

Mixed carcinoma transdifferentiation of bladder urothelial carcinoma after chemotherapy: A case report

Liwei Zhao, Jiaguo Huang, Zhanwen Dong, Ji Sun, Runmiao Hua, Xuliang Wang, Kai Wang
Article Number: 453
Published online on: 10 August 2026

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Primary leiomyosarcoma of the lumbar soft tissue treated with multimodal therapy, including anlotinib: A case report

Jia-Huan Li, De-Xiang Liao, Zhen Hu, Zhi-Yong Zhang, Dan-Dan Ma, Wei-Dong Jin, Tao Fu
Article Number: 452
Published online on: 10 August 2026

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Expression of Concern Open Access

[Expression of Concern] Valosin‑containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF‑κβ/beclin‑1 signaling pathway

Xin Hua Long, Yun Fei Zhou, Min Lan, Shan Hu Huang, Zhi Li Liu, Yong Shu
Article Number: 451
Published online on: 07 August 2026

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Prognostic value of the CONUT score in newly diagnosed diffuse large B‑cell lymphoma

Sema Seçilmiş, Hacer Berna Afacan Öztürk, Birgül Ay Karakuş, Asena Dikyar, Kadir Acar, Ahmet Kürşad Güneş
Article Number: 450
Published online on: 06 August 2026

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DHX15 as a novel immune‑related prognostic biomarker in breast cancer: An integrated bioinformatics analysis with in vitro functional validation

Fan Li, Qin Yue, Jing Li
Article Number: 449
Published online on: 05 August 2026

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Case Report Open Access

Emergence of KRAS mosaicism with multiple variants during treatment with alectinib in ALK‑positive metastatic non‑small cell lung cancer: A case report

Alizée Simon, Gautier Treffel, Guillaume Pax, Guillaume Gauchotte, Marie Husson, Idrissia Hanriot, Agnès Leroux, Jean-Louis Merlin, Alexandre Harlé, Pauline Gilson
Article Number: 448
Published online on: 05 August 2026

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[Expression of Concern] Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation  

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao
Article Number: 447
Published online on: 05 August 2026

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Article

Preliminary study on the efficacy of pazopanib combined with toripalimab as first‑line therapy for metastatic renal cell carcinoma: Real‑world data from a single center

Bin Wang, Tianjun Xing, Hongyu Liu, Xuebing Han, Kai Wu
Article Number: 446
Published online on: 05 August 2026

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Subtype‑specific mechanisms of lipid metabolism in gynecological malignancies and novel targeted intervention strategies (Review)

Yidan Ran
Article Number: 445
Published online on: 04 August 2026

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Chrono‑immunotherapy in genitourinary oncology: From emerging evidence to clinical translation (Review)

Osama Zein Deen, Xin Ye, Patsy Lee, Roxana Astani, Georg Bjarnason, Christian Kollmannsberger, Bernhard Eigl, Guliz Ozgun
Article Number: 444
Published online on: 03 August 2026

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Case Report Open Access

Imaging features and clinical management of mesenteric cavernous lymphangioma: A case report and literature review

Zhongze Zhao, Ermin Cai, Tong Zhou, Jianju Feng, Lingzhi Gu
Article Number: 443
Published online on: 03 August 2026

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Association between the expression of GSTP1 and mutant p53, poor chemotherapy response and metastasis in patients with osteosarcoma

Bangkit Primayudha, Evelina Kodrat, Yogi Prabowo, Aryadi Kurniawan, Nurjati Chairani Siregar, Muhamad Naseh Sajadi Budi Irawan, Rahadyan Magetsari, I Gede Eka Wiratnaya, Istan Irmansyah Irsan, Achmad Fauzi Kamal
Article Number: 442
Published online on: 03 August 2026

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Astragaloside IV suppresses triple‑negative breast cancer cell migration and invasion by targeting BCAT1‑mediated branched‑chain amino acid metabolism

Yi-Ting Liu, Lu Zhang, Xiao-Dong Sun
Article Number: 441
Published online on: 03 August 2026

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LC‑MS/MS‑based clinical value exploration of the methionine cycle in luminal breast cancer

Wenxuan Wu, Yifeng Tu, Han Yao, Yajun Mao, Changfei Mao, Feifei Xu, Zhongcheng Wang
Article Number: 440
Published online on: 03 August 2026

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Article

Accuracy of percutaneous ultrasound‑guided needle biopsy of abdominal lymph nodes for the diagnosis of malignant disease

Camilla Mazzoni, Lisa Argnani, Davide Di Benedetto, Sofia Maria Bakken, Beatrice Casadei, Cinzia Pellegrini, Leonardo De Marco, Marta Machado, Alessandro Broccoli, Pier Luigi Zinzani, Carla Serra
Article Number: 439
Published online on: 03 August 2026

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[Retracted] Esomeprazole affects the proliferation, metastasis, apoptosis and chemosensitivity of gastric cancer cells by regulating lncRNA/circRNA‑miRNA‑mRNA ceRNA networks

Qian Xu, Xiyun Jia, Qian Wu, Lei Shi, Zihan Ma, Nan Ba, Han Zhao, Xingzhou Xia, Zisen Zhang
Article Number: 438
Published online on: 03 August 2026

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Case Report Open Access

Papillary thyroid carcinoma in a patient with long‑standing chronic lymphocytic leukemia: A case report

Jiaxiang Ma, Tieying Gan, Ailin Song, Hongyou Tian, Shaoce Xu, Lei Zhao
Article Number: 437
Published online on: 30 July 2026

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Current status and targeted therapies in endometrial cancer: Molecular classification‑driven treatment strategies (Review)

Xinyu Li, Jie Liu, Fang Huang, Xinyue Deng, Mingxuan Chen, Wen Mou, Wenxia Liu
Article Number: 436
Published online on: 30 July 2026

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Role of lipid‑associated fibroblasts and their signature genes FABP4, CD36 and ABCA8 in gastric cancer progression

Junqun Liao, Lin Wu, Li Zhou, Qiao Ling, Piyun Zhang
Article Number: 435
Published online on: 30 July 2026

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Correction Open Access

[Corrigendum] Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 434
Published online on: 30 July 2026

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Article

Influence of the second primary cancer on clinical outcomes of nasopharyngeal carcinoma following definitive chemoradiotherapy

Shu-Chin Yang, Chung-Han Ho, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, Sheng-Yow Ho
Article Number: 433
Published online on: 29 July 2026

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Review Open Access

ETS transcription factor ELK3: Molecular insights and translational horizons in cancer (Review)

Zhenzhe Liu, Zhong Wei, Zhensheng Li, Liqiang Zhou
Article Number: 432
Published online on: 29 July 2026

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Review Open Access

Bone niche‑driven antitumor immune failure in osteosarcoma: Mechanisms and therapeutic implications (Review)

Bolin Tang, Yuhuai Wu, Jianping Liu, Rui Pan
Article Number: 431
Published online on: 29 July 2026

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Article Open Access

Deep learning model based on CT images to predict Ki‑67 expression in renal carcinoma

Dan Shen, Hongmei Li, Bingye Shi, Tao Ma, Bin Zhou, Chao Gao, Yibo Liu, Zhenyu Cui
Article Number: 430
Published online on: 29 July 2026

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[Retracted] Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 429
Published online on: 29 July 2026

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Article Open Access

Investigation of CRP and NLR as potential biomarkers for redefining biological borderline resectable pancreatic cancer

Keishi Kawasaki, Hidehiro Tajima, Teppei Tatsuoka, Musashi Takada, Soya Meguro, Hirotaka Ishido, Hideyuki Yoshitomi
Article Number: 428
Published online on: 28 July 2026

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Article Open Access

FAM122B acts as an independent poor prognostic factor and promotes the malignant biological behaviors of low‑grade glioma

Hao Wang, Tengfei Guo, Yanbo Gao, Yi Zhou, Rongjun Qian
Article Number: 427
Published online on: 28 July 2026

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Article Open Access

A nomogram based on immunohistochemistry and lymphocyte‑to‑monocyte ratio for predicting risk stratification in endometrial carcinoma

Yunyun Chen, Jianwei Li, Li Yan, Peili Liu, Fanfei Meng, Yajun Zhang
Article Number: 426
Published online on: 28 July 2026

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Correction Open Access

[Corrigendum] Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells

Xiaoyu Zhang, Tianyu Zhai, Zhenyu Hei, Di Zhou, Longyang Jin, Chao Han, Jiandong Wang
Article Number: 425
Published online on: 27 July 2026

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Case Report Open Access

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases 

Noriko Kato, Takashi Yanagawa, Masahiko Okamoto, Tatsuya Ohno, Hirotaka Chikuda
Article Number: 424
Published online on: 23 July 2026

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Correction Open Access

[Corrigendum] Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 423
Published online on: 23 July 2026

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November-2026 Volume 32 Issue 5

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Decitabine induces cell differentiation and growth inhibition accompanied by upregulation of microRNA‑143 and MS4A3 in the myelodysplastic syndromes‑derived leukemic cell line MDS‑L

Rie Nishi, Naoko Hosono, Kaoru Thoyama, Takahiro Yamauchi
Article Number: 518
Published online on: 18 September 2026

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Malignant mesothelioma of the tunica vaginalis testis: A case report

Zhenjiang Liu, Aiyun Han, Shen Li, Jin Zhang, Yuanshan Guo, Chao Sun
Article Number: 517
Published online on: 18 September 2026

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Article Open Access

Methyltransferase‑like 7B promotes M2‑like macrophage polarization in lung adenocarcinoma via upregulating human epidermal growth factor receptor 3 expression and secretion

Sixiao He, Huibin Song, Jie Wu, Jinquan Xia, Ni Liu, Jia Cao, Zixuan Zhang, Xiaolin Cui, Chang Zou
Article Number: 516
Published online on: 18 September 2026

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Exosomal miR‑145‑5p inhibits papillary thyroid cancer by targeting TPM3 and inactivating the PI3K‑Akt pathway

Yunfeng Weng, Xianjiao Cao, Wenyan Song, Qingqing He
Article Number: 515
Published online on: 17 September 2026

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Identification of cancer‑associated fibroblast biomarkers in cutaneous squamous cell carcinoma

Yuanyuan Deng, Jue Qi, Yu Tang, Yueting Cun, Qian He, Li He
Article Number: 514
Published online on: 17 September 2026

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Focal adhesion kinase inhibitor defactinib enhances olaparib‑induced suppression of BRCA‑proficient breast cancer cell proliferation

Hisako Ono, Keiko Taniguchi, Shusuke Yasuda, Mamiko Sukeno, Tomoya Matsui, Yasuto Naoi, Mano Horinaka, Toshiyuki Sakai
Article Number: 513
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Geum-Hwa Lee, Do-Sung Kim, Myung Ja Chung, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae
Article Number: 512
Published online on: 16 September 2026

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Review Open Access

Role of tumor necrosis factor receptor superfamily member 19 in cancer: Diverse functions and therapeutic potential (Review)

Manyu Xu, Zhaoyang Liu, Jingyu Zhang, Hanyun Xu, Yufei Xu, Yue Zhang, Qiong-Ying Hu, Tao Zhang
Article Number: 511
Published online on: 15 September 2026

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Article Open Access

Initiation of immune checkpoint inhibitor therapy in winter is associated with improved overall survival in patients with advanced non‑small cell lung cancer

Zhangxuan Chen, Jingsi Chen, Yang Yao, Xinjing Li, Ranpu Wu, Bingxue Wang, Jiajie Sun, Hongbing Liu
Article Number: 510
Published online on: 15 September 2026

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Article Open Access

Optimal timing of stereotactic radiosurgery with first‑line osimertinib in EGFR‑mutant non‑small cell lung cancer brain metastases: Immediate, early‑consolidation and salvage strategies

Xiaona Zhuang, Xiaoxiao Lu, Junjun Miao, Guangying Hou, Xiangkun Yuan
Article Number: 509
Published online on: 15 September 2026

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Article Open Access

Integrated analysis identified MARK4 as a prognostic and immunomodulatory biomarker in oral squamous cell carcinoma

Xinyue Zhang, Xiaoxue Shen, Sujun Hu, Rui Yao
Article Number: 508
Published online on: 15 September 2026

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Case Report Open Access

Combination of vinorelbine capsules and the small molecule anti‑angiogenic drug apatinib for first‑line treatment of advanced triple‑negative breast cancer with schizophrenia after failure of anthracycline and taxane therapy: A case report

Xue Bai, Liping Chen, Xuelian Chen, Dongcun Wang, Wenyan Kang, Lin Song, Meidi Liu, Caiwen Du
Article Number: 507
Published online on: 15 September 2026

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Review Open Access

Basis and prospects of radiotherapy combined with high‑intensity focused ultrasound ablation (Review)

Lingli Fan, Xiyue Yang, Jie Li, Yao Liao, Yuxi Bai, Xin Mao, Li Yuan, Feng Gao, Gang Feng, Qiuling Shi, Xiaobo Du
Article Number: 506
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] Remodeling of energy metabolism by a ketone body and medium‑chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

Yui Kadochi, Shiori Mori, Rina Fujiwara‑Tani, Yi Luo, Yukiko Nishiguchi, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 505
Published online on: 14 September 2026

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Article Open Access

Melatonin exerts an in vitro anti‑glioblastoma effect through SIRT1‑mediated HMGB1 deacetylation and inhibition of the TLR4/NF‑κB pathway

Beitian Shi, Yu Wang, Chao Zhang, Shiqiang Hou, Ning Lin, Lanlan Zhang
Article Number: 504
Published online on: 14 September 2026

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Case Report Open Access

Concurrent EGFR exon 19 deletion‑insertion and germline BRCA1 alteration in KRAS‑wild‑type pancreatic ductal adenocarcinoma: A case report and review of therapeutic implications

Sheng Yu Wei, Wei Yu, Qiao Huang
Article Number: 503
Published online on: 14 September 2026

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Review Open Access

Effect of extracellular vesicles on malignant tumours: Mechanisms and clinical findings (Review)

Ruiyi Shen, Qihong Lan, Yuan Lu, Ke Wen, Zhenzhen Wei, Qian Liu
Article Number: 502
Published online on: 11 September 2026

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Article

Circulating PCSK9: A new frontier in cancer risk stratification for obese diabetics

Lien-Cheng Tsao, Chen-Ling Kuo, Yu-Shan Cheng, Ching-Shan Huang, Chin-San Liu, Shih-Li Su
Article Number: 501
Published online on: 11 September 2026

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Review Open Access

Multifaceted roles of chemokines in gastric cancer: From tumor microenvironment modulation to therapeutic targeting (Review)

Zhanping Li, Zhongdang Xiao
Article Number: 500
Published online on: 11 September 2026

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Article

Identification and assessment of FN1, MET, KRT19 and CLDN1 as key dysregulated genes in papillary thyroid cancer through transcriptomic profiling and expression analysis

Anette Roxana Gastelum‑Quiroz, Noemí García‑Magallanes, Andrea Ross‑Orozco, Marco Alvarez‑Arrazola, Fred Luque‑Ortega, Karla Lizbeth Morales‑Hernández, Dora Cedano‑Prieto, Vanessa G. Félix, Eliakym Arámbula‑Meraz
Article Number: 499
Published online on: 11 September 2026

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Correction Open Access

[Corrigendum] Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 498
Published online on: 10 September 2026

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Article

Integrated bioinformatics and feature selection-based discovery of ADP-ribosylation-associated biomarkers in non-small cell lung cancer

Jie He, Qingtao Zhao, Hongzhen Zhao, Hua Zhang, Zhonghui Hu, Lingxin Kong, Zengming Wang, Jianghong Yan, Shuo Yang, Shicheng Liu
Article Number: 497
Published online on: 08 September 2026

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Review Open Access

Mechanism‑guided radiosensitization strategies for nasopharyngeal carcinoma: Current evidence and translational perspectives (Review)

Wei Deng, Ziyun Li, Zhenhua Zhu
Article Number: 496
Published online on: 08 September 2026

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Retraction Open Access

[Retracted] Characterization of sonic hedgehog inhibition in gastric carcinoma cells

Ruxue Bai, Hongchuan Zhao, Xiang Zhang, Shiyu Du
Article Number: 495
Published online on: 08 September 2026

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Article Open Access

KLF2 as a prognostic and potential therapeutic target associated with ferroptosis in serous ovarian cancer: An integrative bioinformatics and clinical validation study

Yuanyi Wang, Juan Yu, Wu Huang, Yuan Yuan, Xiangbo Lan, Youli Jian, Xiao Li, Simei Wang, Xiao Huang, Ge Xu, Xing Wei
Article Number: 494
Published online on: 07 September 2026

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Case Report Open Access

Pathological transformation of rectal adenocarcinoma to choriocarcinoma in a male patient: A case report and review of the literature

Yefang Lao, Xikai Zhang, Zhongzhong Peng, Xiao Zhou, Xianyuan Miao, Qiongqiong Wang, Sijia Ren, Kaifeng Wang, Hongmin Lu
Article Number: 493
Published online on: 07 September 2026

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Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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