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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2018 Volume 16 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Anti‑inflammatory and antitumor action of hydrogen via reactive oxygen species (Review)

Ye Yang, Yaping Zhu, Xiaowei Xi
Pages: 2771-2776
Published online on: 26 June 2018

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Review

MicroRNA‑21: A promising biomarker for the prognosis and diagnosis of non‑small cell lung cancer (Review)

Wen Zheng, Juanjuan Zhao, Yijing Tao, Mengmeng Guo, Zhou Ya, Chao Chen, Nalin Qin, Jing Zheng, Junmin Luo, Lin Xu
Pages: 2777-2782
Published online on: 15 June 2018

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Case Report Open Access

Adenoid cystic carcinoma of the larynx in a 70-year-old patient: A case report

Filippo Ricciardiello, Raffaele Addeo, Antonella Miriam Di Lullo, Teresa Abate, Salvatore Mazzone, Flavia Oliva, Giovanni Motta, Michelle Caraglia, Massimo Mesolella
Pages: 2783-2788
Published online on: 18 June 2018

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Article Open Access

Gene therapy of renal cancer using recombinant adeno‑associated virus encoding human endostatin

Erlin Sun, Ruifa Han, Bingxin Lu
Pages: 2789-2796
Published online on: 28 June 2018

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Article Open Access

MEG‑3‑mediated Wnt/β‑catenin signaling pathway controls the inhibition of tunicamycin‑mediated viability in glioblastoma Retraction in /10.3892/ol.2025.15162

Xiangyu Cui, Dezhou Sun, Bin Shen, Xin Wang
Pages: 2797-2804
Published online on: 28 June 2018

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Article Open Access

Doxorubicin combined with Notch1‑targeting siRNA for the treatment of gastric cancer

Wei Zhou, Wei Tan, Xu Huang, Hong Gang Yu
Pages: 2805-2812
Published online on: 28 June 2018

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Article Open Access

Antitumor efficacy of the Runx2‑dendritic cell vaccine in triple‑negative breast cancer in vitro

Mi Tang, Yu Liu, Qiao‑Chu Zhang, Peng Zhang, Jue‑Kun Wu, Jia‑Ni Wang, Ying Ruan, Yong Huang
Pages: 2813-2822
Published online on: 21 June 2018

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Article Open Access

Overexpression of TPX2 is associated with progression and prognosis of prostate cancer

Jun Zou, Rui‑Yan Huang, Fu‑Neng Jiang, De‑Xiong Chen, Cong Wang, Zhao‑Dong Han, Yu‑Xiang Liang, Wei‑De Zhong
Pages: 2823-2832
Published online on: 25 June 2018

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Article Open Access

Liver receptor homologue 1, a novel prognostic marker in colon cancer patients

Cong Wu, Jin Feng, Ling Li, Yugang Wu, Haibin Xie, Yong Yin, Jing Ye, Zhong Li
Pages: 2833-2838
Published online on: 18 June 2018

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Article Open Access

Impact of liver tumor percutaneous radiofrequency ablation on circulating tumor cells

Yang Li, Na Huang, Chunlin Wang, Huanrong Ma, Minyu Zhou, Li Lin, Zhenhua Huang, Li Sun, Min Shi, Wangjun Liao
Pages: 2839-2850
Published online on: 25 June 2018

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Article Open Access

AG490 reverses phenotypic alteration of dendritic cells by bladder cancer cells

Weigang Xiu, Juan Ma, Ting Lei, Man Zhang
Pages: 2851-2856
Published online on: 27 June 2018

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Article Open Access

Wnt2 contributes to the progression of gastric cancer by promoting cell migration and invasion

Zhaoran Zhang, Jinyan Wang, Xiang Dong
Pages: 2857-2864
Published online on: 28 June 2018

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Article Open Access

Silencing long non‑coding RNA, differentiation antagonizing non‑protein coding RNA promotes apoptosis and inhibits tumor growth in colon cancer

Xiao‑Jin Yang, Jing‑Jing Zhao, Wei‑Jun Chen, Gen‑Gen Zhang, Wei Wang, Han‑Chuan Tao
Pages: 2865-2872
Published online on: 28 June 2018

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Article Open Access

Skp2 expression has different clinicopathological and prognostic implications in lung adenocarcinoma and squamous cell carcinoma

Kaize Zhong, Fan Yang, Qiuying Han, Jing Chen, Jun Wang
Pages: 2873-2880
Published online on: 20 June 2018

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Article Open Access

Overexpression of macrophage migration inhibitory factor and functionally‑related genes, D‑DT, CD74, CD44, CXCR2 and CXCR4, in glioblastoma

Mario Presti, Emanuela Mazzon, Maria Sofia Basile, Maria Cristina Petralia, Alessia Bramanti, Giuseppe Colletti, Placido Bramanti, Ferdinando Nicoletti, Paolo Fagone
Pages: 2881-2886
Published online on: 19 June 2018

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Article Open Access

Epstein‑Barr virus‑encoded microRNA BART7 downregulates major histocompatibility complex class I chain‑related peptide A and reduces the cytotoxicity of natural killer cells to nasopharyngeal carcinoma

Thian‑Sze Wong, Siqi Chen, Min‑Juan Zhang, Jimmy Yu‑Wai Chan, Wei Gao
Pages: 2887-2892
Published online on: 28 June 2018

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Article Open Access

VTIQ evaluates antitumor effects of NET‑1 siRNA by UTMD in HCC xenograft models

Xitian Liang, Bolin Wu, Haitao Shang, Xue Han, Hui Jing, Yixin Sun, Wen Cheng
Pages: 2893-2902
Published online on: 19 June 2018

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Article Open Access

SMOC1 silencing suppresses the angiotensin II‑induced myocardial fibrosis of mouse myocardial fibroblasts via affecting the BMP2/Smad pathway

Yize Wang, Xianming Wu
Pages: 2903-2910
Published online on: 19 June 2018

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Article Open Access

Tumor targeting with docosahexaenoic acid‑conjugated docetaxel for inhibiting lung cancer metastasis to bone

Shougang Jiang, Zhiguo Liu, Lei Wu, Yingjie Yuan, Yan Hu, Xingyao Zhang, Liang Wei, Yuangang Zu
Pages: 2911-2920
Published online on: 28 June 2018

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Article Open Access

Calcium gluconate alleviates the toxic effect of hydrofluoric acid on human dermal fibroblasts through the Wnt/β‑catenin pathway

Jinxia Peng, Rui Liu, Ling Peng, Hongtao Jia
Pages: 2921-2928
Published online on: 18 June 2018

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Article Open Access

Clinical characteristics and prognosis of pediatric patients with B cell acute lymphoblastic leukemia relapse

Xiaohong Zhang, Haixia Wu, Hong Fan, Baifang Su, Ge Zhang, Lin Dong
Pages: 2929-2934
Published online on: 18 June 2018

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Article Open Access

Prognostic value of IL‑6R mRNA in lung adenocarcinoma and squamous cell carcinoma

Bin Xu, Qu Chen, Cuihua Yue, Lei Lan, Jingting Jiang, Yueping Shen, Binfeng Lu
Pages: 2935-2948
Published online on: 28 June 2018

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Article Open Access

Resveratrol induces apoptosis in SGC‑7901 gastric cancer cells

Xiaoxue Wu, Yundan Xu, Biran Zhu, Qiang Liu, Qunfeng Yao, Gang Zhao
Pages: 2949-2956
Published online on: 28 June 2018

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Article Open Access

Medicinal supplement genipin induces p53 and Bax‑dependent apoptosis in colon cancer cells

Jingwang Ye, Jing Li, Xiangfeng Wang, Ling Li
Pages: 2957-2964
Published online on: 26 June 2018

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Article Open Access

Matrine inhibits TPC‑1 human thyroid cancer cells via the miR‑21/PTEN/Akt pathway

Lina Zhao, Xianyu Zhang, Shusen Cui
Pages: 2965-2970
Published online on: 21 June 2018

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Article Open Access

Clinical significance of tumor necrosis factor receptor 2 in middle and lower thoracic esophageal squamous cell carcinoma

Dong Yang, Ruidong Li, Huili Wang, Junye Wang, Ye Li, Hongbo Wang, Wei Wang, Zifeng Liu
Pages: 2971-2978
Published online on: 20 June 2018

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Case Report Open Access

Complete cure of a patient with HBV‑associated hepatocellular carcinoma with lung metastasis using interferon and survival up to 108 months: A case report and literature review

Fang Wang, Hongmin Lv, Yan Li, Tao Han, Hui Liu, Kefeng Jia, Fang Liu, Yanying Gao, Fengmei Wang
Pages: 2979-2988
Published online on: 28 June 2018

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Article Open Access

Clinical significance of chromodomain helicase/ATPase DNA binding protein 1‑like and human mutL homolog 1 gene expression in cholangiocarcinoma

Jingwen Hua, Shiniao Li, Changwen Huang
Pages: 2989-2994
Published online on: 28 June 2018

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Article Open Access

Extramedullary plasmacytoma of the larynx: Literature review and report of a case who subsequently developed acute myeloid leukemia

Shenglei Ge, Ganghua Zhu, Yan Yi
Pages: 2995-3004
Published online on: 19 June 2018

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Article Open Access

miR-16 targets SALL4 to repress the proliferation and migration of gastric cancer

Xuefeng Jiang, Zhe Wang
Pages: 3005-3012
Published online on: 20 June 2018

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Article Open Access

The knockdown of the Mediator complex subunit MED15 restrains urothelial bladder cancer cells' malignancy

Isabella Syring, Richard Weiten, Tim Müller, Doris Schmidt, Susanne Steiner, Glen Kristiansen, Stefan C. Müller, Jörg Ellinger
Pages: 3013-3021
Published online on: 25 June 2018

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Article Open Access

Immunological effects of a low‑dose cytarabine, aclarubicin and granulocyte‑colony stimulating factor priming regimen on a mouse leukemia model

Jinqiu Chen, Nan Yang, Hailing Liu, Huan Yao, Jin Wang, Yun Yang, Wanggang Zhang
Pages: 3022-3028
Published online on: 25 June 2018

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Article Open Access

Decreased expression level and DNA‑binding activity of specificity protein 1 via cyclooxygenase‑2 inhibition antagonizes radiation resistance, cell migration and invasion in radiation‑resistant lung cancer cells

Ruijun Liu, Qiang Tan, Qingquan Luo
Pages: 3029-3037
Published online on: 28 June 2018

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Article Open Access

MicroRNA‑30a suppresses the proliferation, migration and invasion of human renal cell carcinoma cells by directly targeting ADAM9 Retraction in /10.3892/ol.2024.14232

Lining Jiang, Yabin Liu, Can Ma, Binghui Li
Pages: 3038-3044
Published online on: 20 June 2018

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Article Open Access

Role of regulatory T cells and CD8+ T lymphocytes in the dissemination of circulating tumor cells in primary invasive breast cancer

Dandan Xue, Tiansong Xia, Jue Wang, Meihong Chong, Shui Wang, Chunhui Zhang
Pages: 3045-3053
Published online on: 19 June 2018

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Article Open Access

Burkitt lymphoma‑associated network construction and important network motif analysis

Kunhao Wang, Chao Ma, Chong Xing, Chin‑Ling Chen, Zhigang Chen, Yuxia Yao, Jianan Wang, Chunyu Tao
Pages: 3054-3062
Published online on: 21 June 2018

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Article Open Access

miR-106b targets DAB2 to promote hepatocellular carcinoma cell proliferation and metastasis

Chunhui Sun, Xun Yao, Qingyu Jiang, Xiuyong Sun
Pages: 3063-3069
Published online on: 15 June 2018

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Article Open Access

Role of PLK1 signaling pathway genes in gastrointestinal stromal tumors

Jen‑Shi Chen, Chun‑Nan Yeh, Chi‑Tung Cheng, Chueh‑Chuan Yen, Yen‑Yang Chen, Shih‑Chiang Huang, Kun‑Chun Chiang, Ta‑Sen Yeh, San‑Chi Chen, Ta‑Chung Chao, Muh‑Hwa Yang, Yee Chao
Pages: 3070-3082
Published online on: 21 June 2018

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Article Open Access

Anterior gradient 2 as a supervisory marker for tumor vessel normalization induced by anti‑angiogenic treatment

Fan Pan, Wei Li, Wende Yang, Xiao‑Yan Yang, Shuhao Liu, Xin Li, Xiaoxu Zhao, Hui Ding, Li Qin, Yunlong Pan
Pages: 3083-3091
Published online on: 20 June 2018

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Article Open Access

Screening and identification of key biomarkers in bladder carcinoma: Evidence from bioinformatics analysis

Meiqin Yan, Xuan Jing, Yina Liu, Xiangrong Cui
Pages: 3092-3100
Published online on: 21 June 2018

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Article Open Access

miR-185 inhibits cell migration and invasion of hepatocellular carcinoma through CDC42 Erratum in /10.3892/ol.2019.11186

Qingjun Zhang, Yun Chen, Ke Liu
Pages: 3101-3107
Published online on: 15 June 2018

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Article Open Access

Effect of chelidonine on growth, invasion, angiogenesis and gene expression in head and neck cancer cell lines

Ruth Herrmann, Jeanette Roller, Christine Polednik, Marianne Schmidt
Pages: 3108-3116
Published online on: 27 June 2018

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Article Open Access

Homogenously isoattenuating insulinoma on biphasic contrast‑enhanced computed tomography: Little benefits of diffusion‑weighted imaging for lesion detection

Zhenshan Shi, Xiumei Li, Ruixiong You, Yueming Li, Xianying Zheng, Kamisha Ramen, Vikash Sahadeo Loosa, Dairong Cao, Qunlin Chen
Pages: 3117-3125
Published online on: 28 June 2018

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Article Open Access

Tubeimoside‑1 inhibits the proliferation and metastasis by promoting miR‑126‑5p expression in non‑small cell lung cancer cells

Hanbing Shi, Hongxia Bi, Xingyuan Sun, Haiying Dong, Yunfei Jiang, Haijun Mu, Wei Li, Guohua Liu, Ruizhi Gao, Jiang Su
Pages: 3126-3134
Published online on: 29 June 2018

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Article Open Access

Clinical significance of cytokeratin in the cervical lymph nodes of patients with mandibular gingival squamous cell carcinoma

Qingyun Duan, Mei Xu, Xiong Zhang, Muyun Jia, Rongtao Yuan, Min Gan
Pages: 3135-3139
Published online on: 21 June 2018

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Article Open Access

Expression of miR-30c and miR-29b in prostate cancer and its diagnostic significance

Chuanan Zhu, Xiumei Hou, Jiabin Zhu, Chunxiao Jiang, Wei Wei
Pages: 3140-3144
Published online on: 21 June 2018

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Article Open Access

A study on the biological function of heat shock factor 1 proteins in breast cancer

Xiaolan Wang, Dianlong Zhang, Mingqian Cao, Jinling Ba, Bin Wu, Tao Liu, Chen Nie
Pages: 3145-3149
Published online on: 28 June 2018

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Article Open Access

miR‑18a‑5p promotes cell invasion and migration of osteosarcoma by directly targeting IRF2

Chao Lu, Kan Peng, Hao Guo, Xiaoyu Ren, Shouye Hu, Yuanzhen Cai, Yan Han, Le Ma, Peng Xu
Pages: 3150-3156
Published online on: 27 June 2018

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Article Open Access

Radiofrequency ablation combined with esophageal stent in the treatment of malignant esophageal stenosis: A single-center prospective study

Yonggui Zhang, Mingwei Zhou, Lin Bai, Rongyan Han, Kang Lv, Zhe Wang
Pages: 3157-3161
Published online on: 28 June 2018

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Article

Anticancer effect of salidroside reduces viability through autophagy/PI3K/Akt and MMP‑9 signaling pathways in human bladder cancer cells

Tian Li, Kewei Xu, Yifan Liu
Pages: 3162-3168
Published online on: 18 June 2018

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Article

MicroRNA‑376a regulates cell proliferation and apoptosis by targeting forkhead box protein P2 in lymphoma

Shuna Yao, Yanyan Liu, Zhihua Yao, Yan Zhao, Haiying Wang, Yuanlin Xu, Jiuyang Zhang, Jing Li, Shujun Yang
Pages: 3169-3176
Published online on: 22 June 2018

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Article

Deoxypodophyllotoxin induces cell cycle arrest and apoptosis in human cholangiocarcinoma cells

Meifang Xiao, Xuegong Fan, Yongming Fu, Yujuan Zhou, Shaohui Liu, Shifang Peng
Pages: 3177-3182
Published online on: 18 June 2018

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Article

Potential biomarkers of HCC based on gene expression and DNA methylation profiles

Chao Meng, Xiaomin Shen, Wentao Jiang
Pages: 3183-3192
Published online on: 26 June 2018

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Article

Mitochondrial ROS activate interleukin‑1β expression in allergic rhinitis

Qiping Shi, Zhiwei Lei, Gui Cheng, Dehai Li, Qian Wang, Simin Luo, Hengwen Yang, Haiying Jia
Pages: 3193-3200
Published online on: 18 June 2018

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Article

The diagnostic value of PI‑RADS V1 and V2 using multiparametric MRI in transition zone prostate clinical cancer

Ximing Wang, Jie Bao, Xiaoxia Ping, Chunhong Hu, Jianquan Hou, Fenglin Dong, Lingchuan Guo
Pages: 3201-3206
Published online on: 28 June 2018

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Article

Scinderin‑knockdown inhibits proliferation and promotes apoptosis in human breast carcinoma cells

Wenjing Jian, Xiaoli Zhang, Jiguo Wang, Yunlong Liu, Chuting Hu, Xianming Wang, Renbin Liu
Pages: 3207-3214
Published online on: 21 June 2018

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Article

Value of systemic PET/CT in the diagnosis and differential diagnosis of aplastic anemia

Meilan Chen, Liyuan Lu, Juan Li, Bin Zhang, Junru Liu, Jingli Gu, Dong Zheng, Xiuzhen Tong, Hehua Wang
Pages: 3215-3222
Published online on: 28 June 2018

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Article

The impact of exogenous CO releasing molecule CORM‑2 on inflammation and signaling of orthotopic lung cancer

Li Shao, Congyang Liu, Shuhua Wang, Jiannan Liu, Li Wang, Liping Lv, Yong Zou
Pages: 3223-3230
Published online on: 26 June 2018

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Article

Identification of six serum antigens and autoantibodies for the detection of early stage epithelial ovarian carcinoma by bioinformatics analysis and liquid chip analysis

Yupeng Zou, Li Li
Pages: 3231-3240
Published online on: 26 June 2018

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Article

Anti‑Condyloma acuminata mechanism of microRNAs‑375 modulates HPV in cervical cancer cells via the UBE3A and IGF‑1R pathway

Shuying Wu, Hong Chen
Pages: 3241-3247
Published online on: 18 June 2018

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Article

Knockdown of lncRNA TP73‑AS1 inhibits gastric cancer cell proliferation and invasion via the WNT/β‑catenin signaling pathway

Yufeng Wang, Shuai Xiao, Bingyi Wang, Yang Li, Quanning Chen
Pages: 3248-3254
Published online on: 28 June 2018

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Article

Cell‑free culture conditioned medium elicits pancreatic β cell lineage‑specific epigenetic reprogramming in mice

Koichi Kawamoto, Tomofumi Ohashi, Masamitsu Konno, Naohiro Nishida, Jun Koseki, Hidetoshi Matsui, Daisuke Sakai, Toshihiro Kudo, Hidetoshi Eguchi, Taroh Satoh, Yuichiro Doki, Masaki Mori, Hideshi Ishii
Pages: 3255-3259
Published online on: 21 June 2018

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Article

Anti‑Müllerian hormone inhibits proliferation and induces apoptosis in epithelial ovarian cancer cells by regulating the cell cycle and decreasing the secretion of stem cell factor

Tiansong Zhang, Linhao Deng, Qian Xiong, Shujun Su, Jian Gu
Pages: 3260-3266
Published online on: 18 June 2018

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Article

Serum exosomal microRNA‑122 and microRNA‑21 as predictive biomarkers in transarterial chemoembolization‑treated hepatocellular carcinoma patients

Tomoyuki Suehiro, Hisamitsu Miyaaki, Yasuko Kanda, Hidetaka Shibata, Takuya Honda, Eisuke Ozawa, Satoshi Miuma, Naota Taura, Kazuhiko Nakao
Pages: 3267-3273
Published online on: 19 June 2018

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Article

Thymidylate synthase predicts poor response to pemetrexed chemotherapy in patients with advanced breast cancer

Fei Shan, Yu‑Lin Liu, Qiang Wang, Yan‑Long Shi
Pages: 3274-3280
Published online on: 15 June 2018

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Article

Optimized lymph node dissection range during progression of lower thoracic esophageal squamous cell carcinoma in the latest therapeutic surgical strategy: A retrospective analysis

Hiroki Harada, Kei Hosoda, Hiromitsu Moriya, Hiroaki Mieno, Akira Ema, Marie Washio, Yoshimasa Kosaka, Masahiko Watanabe, Keishi Yamashita
Pages: 3281-3289
Published online on: 27 June 2018

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Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis Corrigendum in /10.3892/ol.2026.15649

Jianfeng Xu, Lei Yang, Liang Dong
Pages: 3290-3296
Published online on: 26 June 2018

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Article

Anticancer effect of resibufogenin on gastric carcinoma cells through the phosphoinositide 3‑kinase/protein kinase B/glycogen synthase kinase 3β signaling pathway

Zhen Lu, Aman Xu, Xiao Yuan, Kaiwei Chen, Likun Wang, Tao Guo
Pages: 3297-3302
Published online on: 18 June 2018

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Article

Circulating plasma microRNAs in the detection of esophageal squamous cell carcinoma

Lu Zhang, Bing Dong, Pengfei Ren, Hua Ye, Jianxiang Shi, Jiejie Qin, Kaijuan Wang, Peng Wang, Jianying Zhang
Pages: 3303-3318
Published online on: 20 June 2018

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Article

Upregulation of miR‑375 inhibits human liver cancer cell growth by modulating cell proliferation and apoptosis via targeting ErbB2

Lina Li, Liping Jia, Yan Ding
Pages: 3319-3326
Published online on: 22 June 2018

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Article

The protective effect of puerarin on angiotensin II‑induced aortic aneurysm formation by the inhibition of NADPH oxidase activation and oxidative stress‑triggered AP‑1 signaling pathways

Jie Yue, Shunwu Chang, Zhanxiang Xiao, Youfei Qi, Jianxing He
Pages: 3327-3332
Published online on: 26 June 2018

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Article

Oridonin inhibits growth and induces apoptosis of human neurocytoma cells via the Wnt/β‑catenin pathway

Jingyan Liang, Weiguang Wang, Lifu Wei, Shan Gao, Yingge Wang
Pages: 3333-3340
Published online on: 18 June 2018

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Article

Arsenic trioxide and sorafenib combination therapy for human hepatocellular carcinoma functions via up‑regulation of TNF‑related apoptosis‑inducing ligand

Lingyan Wang, Zhihui Min, Xiangdong Wang, Mushuang Hu, Dongli Song, Zhenggang Ren, Yunfeng Cheng, Yanhong Wang
Pages: 3341-3350
Published online on: 18 June 2018

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Article

Oncostatin M treatment increases the responsiveness toward cisplatin‑based chemoradiotherapy in cervical cancer cells in a STAT3‑dependent manner

Russalina Stroeder, Barbara Walch‑Rückheim, Jil Fischbach, Ingolf Juhasz‑Böss, Christian Rübe, Erich‑Franz Solomayer, Sigrun Smola
Pages: 3351-3358
Published online on: 18 June 2018

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Article

MicroRNA‑2682‑3p inhibits osteosarcoma cell proliferation by targeting CCND2, MMP8 and Myd88

Fan Zhang, Yanjie Zhu, Guoxin Fan, Shuo Hu
Pages: 3359-3364
Published online on: 27 June 2018

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Article

Long non‑coding RNA H19 promotes the migration and invasion of colon cancer cells via MAPK signaling pathway

Weiwei Yang, Rajkumar Ezakiel Redpath, Chongyou Zhang, Ning Ning
Pages: 3365-3372
Published online on: 29 June 2018

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Article

Downregulation of BIRC5 inhibits the migration and invasion of esophageal cancer cells by interacting with the PI3K/Akt signaling pathway

Xiaobin Shang, Guoyan Liu, Yuefeng Zhang, Peng Tang, Hongdian Zhang, Hongjing Jiang, Zhentao Yu
Pages: 3373-3379
Published online on: 18 June 2018

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Article

Preliminary evaluation of the potential role of β‑elemene in reversing erlotinib‑resistant human NSCLC A549/ER cells

Lan Lin, Lianbin Li, Xiangqi Chen, Bangwei Zeng, Tingyan Lin
Pages: 3380-3388
Published online on: 18 June 2018

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Article

Carbon ion beam radioresistant rodent cells are sensitized to trifluorothymidine exposure

Sung‑Jae Baek, Katsutoshi Sato, Naohiro Nishida, Jun Koseki, Kazuhiko Hayashi, Koichi Kawamoto, Masamitsu Konno, Yuichiro Doki, Masaki Mori, Kazuhiko Ogawa, Hideshi Ishii
Pages: 3389-3393
Published online on: 21 June 2018

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Article

DNA double strand breaks induced by low dose mammography X‑rays in breast tissue: A pilot study

Julie Depuydt, Tanguy Viaene, Phillip Blondeel, Nathalie Roche, Rudy Van den Broecke, Hubert Thierens, Anne Vral
Pages: 3394-3400
Published online on: 26 June 2018

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Article

Association between the overexpression of PBOV1 and the prognosis of patients with hepatocellular carcinoma

Chengbiao Xue, Zibiao Zhong, Shaojun Ye, Yanfeng Wang, Qifa Ye
Pages: 3401-3407
Published online on: 25 June 2018

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Correction Open Access

[Erratum] BRCA1 homozygous unclassified variant in a patient with non‑Fanconi anemia: A case report

Davide Bondavalli, Francesca Malvestiti, Valeria Pensotti, Irene Feroce, Bernardo Bonanni
Pages: 3408-3408
Published online on: 25 June 2018

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Correction Open Access

[Corrigendum] Label‑free quantitative proteomic analysis identifies CTNNB1 as a direct target of FOXP3 in gastric cancer cells

Du‑Yi Pan, Xiao‑Qing Zeng, Gui‑Fen Ma, Jing Gao, Na Li, Qing Miao, Jing‑Jing Lian, Hu Zhou, Li‑Li Xu, Shi‑Yao Chen
Pages: 3409-3409
Published online on: 25 June 2018

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Review

Electrochemotherapy in head and neck cancer: A review of an emerging cancer treatment (Review)

Armando De Virgilio, Massimo Ralli, Lucia Longo, Patrizia Mancini, Giuseppe Attanasio, Francesca Atturo, Marco De Vincentiis, Antonio Greco
Pages: 3415-3423
Published online on: 12 July 2018

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Review

The role of lncRNAs in the development of endometrial carcinoma (Review)

Bi‑Lan Li, Xiao‑Ping Wan
Pages: 3424-3429
Published online on: 04 July 2018

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Article Open Access

Recurrence‑associated factors of laparoscopic adenomyomectomy for severely symptomatic adenomyoma

Wentao Yu, Guanyuan Liu, Chongdong Liu, Zhenyu Zhang
Pages: 3430-3438
Published online on: 05 July 2018

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Article Open Access

In vivo acquired sorafenib‑resistant patient‑derived tumor model displays alternative angiogenic pathways, multi‑drug resistance and chromosome instability

Gang Hu, Yixin Zhang, Kedong Ouyang, Fubo Xie, Houshun Fang, Xueyang Yang, Kunyan Liu, Zongyu Wang, Xuzhen Tang, Jibin Liu, Lei Yang, Zhenzhou Jiang, Weikang Tao, He Zhou, Luyong Zhang
Pages: 3439-3446
Published online on: 04 July 2018

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Article Open Access

Identification of genes that predict the biochemical recurrence of prostate cancer

Jianfeng Chu, Ning Li, Wentao Gai
Pages: 3447-3452
Published online on: 10 July 2018

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Article Open Access

Downregulation of ERBB3 decreases the proliferation, migration and invasion of cervical cancer cells though the interaction with MTK‑1

Jingyun Du, Shihua Zhou, Li Wang, Mulan Yu, Liyan Mei
Pages: 3453-3458
Published online on: 05 July 2018

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microRNA‑761 regulates glycogen synthase kinase 3β expression and promotes the proliferation and cell cycle of human gastric cancer cells

Xinfang Sun, Hongtao Hou, Ke Li, Mingming Zheng
Pages: 3459-3464
Published online on: 11 July 2018

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Article Open Access

Expression of V‑domain immunoglobulin suppressor of T cell activation is associated with the advanced stage and presence of lymph node metastasis in ovarian cancer

Hong Liao, Hongmei Zhu, Shanling Liu, He Wang
Pages: 3465-3472
Published online on: 02 July 2018

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Article Open Access

Expression of ELF5 in endometrial carcinoma tissues and its clinical significance

He Yang, Hongchao Yan
Pages: 3473-3480
Published online on: 05 July 2018

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Article Open Access

Downregulation of Dock1 and Elmo1 suppresses the migration and invasion of triple‑negative breast cancer epithelial cells through the RhoA/Rac1 pathway

Yueyang Liang, Shushu Wang, Yi Zhang
Pages: 3481-3488
Published online on: 04 July 2018

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Article Open Access

Dual targeting of survivin and X‑linked inhibitor of apoptosis protein suppresses the growth and promotes the apoptosis of gastric cancer HGC‑27 cells

Yanfeng Li, Wenbo Gao, Yan Ma, Guanyu Zhu, Fuhui Chen, Hongyan Qu
Pages: 3489-3498
Published online on: 05 July 2018

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Article Open Access

Ferritin level prospectively predicts hepatocarcinogenesis in patients with chronic hepatitis B virus infection

Zhenyuan Bian, Hie‑Won Hann, Zhong Ye, Chun Yin, Yang Wang, Wan Fang, Shaogui Wan, Chun Wang, Kaishan Tao
Pages: 3499-3508
Published online on: 06 July 2018

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Article Open Access

Autophagy inhibitor chloroquine induces apoptosis of cholangiocarcinoma cells via endoplasmic reticulum stress

Baoxing Jia, Yanan Xue, Xiaoyu Yan, Jiuling Li, Yao Wu, Rui Guo, Juanjuan Zhang, Lichao Zhang, Yaping Li, Yahui Liu, Liankun Sun
Pages: 3509-3516
Published online on: 11 July 2018

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Article Open Access

ARHGAP24 regulates cell ability and apoptosis ofcolorectal cancer cells via the regulation of P53

Suiliang Zhang, Liang Sui, Juhua Zhuang, Saifei He, Yanan Song, Ying Ye, Wei Xia
Pages: 3517-3524
Published online on: 04 July 2018

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Article Open Access

miR-486-5p inhibits cell proliferation and invasion through repressing GAB2 in non-small cell lung cancer

Sunfeng Yu, Shuang Geng, Yi Hu
Pages: 3525-3530
Published online on: 29 June 2018

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Article Open Access

Retrospective study on recovery of 521 gastrointestinal tumor patients after laparoscopic surgery

Jiakun Shi, Shengjie Li, Yujie Wang, Lei Zheng
Pages: 3531-3536
Published online on: 04 July 2018

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Article

Upregulating MMP‑1 in carcinoma‑associated fibroblasts reduces the efficacy of Taxotere on breast cancer synergized by Collagen IV

Qingyu Cui, Bixiao Wang, Kaifu Li, Haichen Sun, Tao Hai, Yan Zhang, Hua Kang
Pages: 3537-3544
Published online on: 05 July 2018

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Article Open Access

Homoisoflavanone‑1 isolated from Polygonatum odoratum arrests the cell cycle and induces apoptosis in A549 cells

Deli Ning, Ming Jin, Tao Xv, Jikai Sun, Min Li
Pages: 3545-3554
Published online on: 05 July 2018

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Case Report Open Access

Abscopal effect of radiation on lymph node metastasis in esophageal carcinoma: A case report and literature review

Xiangfei Zhao, Jingbo Kang, Rugang Zhao
Pages: 3555-3560
Published online on: 05 July 2018

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Article Open Access

miR‑329 inhibits papillary thyroid cancer progression via direct targeting WNT1

Liang Wu, Fulai Pei, Xiaojuan Men, Kai Wang, Deliang Ma
Pages: 3561-3568
Published online on: 06 July 2018

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Article Open Access

Ailanthone induces autophagic and apoptotic cell death in human promyelocytic leukemia HL‑60 cells

Cheng Wei, Chuanrong Chen, Yuxin Cheng, Lin Zhu, Yu Wang, Can Luo, Yang He, Zhiming Yang, Zhaoning Ji
Pages: 3569-3576
Published online on: 06 July 2018

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Article Open Access

Exopolysaccharides produced by Lactobacillus strains suppress HT‑29 cell growth via induction of G0/G1 cell cycle arrest and apoptosis

Wei Di, Lanwei Zhang, Huaxi Yi, Xue Han, Yingchun Zhang, Liang Xin
Pages: 3577-3586
Published online on: 11 July 2018

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miR-329 regulates the sensitivity of 5-FU in chemotherapy of colorectal cancer by targeting E2F1

Jie Yin, Xiping Shen, Mei Li, Fangying Ni, Li Xu, Hua Lu
Pages: 3587-3592
Published online on: 11 July 2018

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Prognostic importance of bile duct invasion in surgical resection with curative intent for hepatocellular carcinoma using PSM analysis

Xinwei Yang, Zhiquan Qiu, Rongzhen Ran, Longjiu Cui, Xiangji Luo, Mengchao Wu, Wei‑Feng Tan, Xiaoqing Jiang
Pages: 3593-3602
Published online on: 10 July 2018

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High PKM2 expression is independently correlated with decreased overall survival in hepatocellular carcinoma

Dong‑Hui Lu, Wen‑Wen Lv, Wen‑Xing Li, Yue‑Dong Gao
Pages: 3603-3610
Published online on: 06 July 2018

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Article Open Access

Error analysis of applicator position for combined internal/external radiation therapy in cervical cancer

Wei Ying, Li Liang, Yu Wang, Guo-Hai Qi
Pages: 3611-3613
Published online on: 02 July 2018

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Article Open Access

Protective effect and mechanism of rat recombinant S100 calcium‑binding protein A4 on oxidative stress injury of rat vascular endothelial cells

Xiangyan Meng, Xiujie Gao, Zhiqing Zhang, Xuesi Zhou, Lei Wu, Miaomiao Yang, Kun Wang, Hanlin Ren, Bei Sun, Tianhui Wang
Pages: 3614-3622
Published online on: 11 July 2018

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PET/CT imaging analysis of recurrent sites and patterns of spread following modified radical surgery (type B) for stage Ib‑IIa cervical cancer

Shuxia Cheng, Yanmei Li, Mingchuan Zhang, Tingting Tong
Pages: 3623-3627
Published online on: 04 July 2018

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Article Open Access

Betulinic acid exerts potent antitumor effects on paclitaxel‑resistant human lung carcinoma cells (H460) via G2/M phase cell cycle arrest and induction of mitochondrial apoptosis

Xiao‑Kai Zhan, Jun‑Ling Li, Sen Zhang, Pu‑Yuan Xing, Meng‑Fan Xia
Pages: 3628-3634
Published online on: 06 July 2018

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Article Open Access

DNM1L, a key prognostic predictor for gastric adenocarcinoma, is involved in cell proliferation, invasion, and apoptosis

Xiao‑Wu Xu, Xiao‑Min Yang, Wei‑Jia Zhao, Lei Zhou, De‑Chun Li, Yi‑Hu Zheng
Pages: 3635-3641
Published online on: 11 July 2018

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Identification and verification of differentially expressed microRNAs and their target genes for the diagnosis of esophageal cancer

Xiaoyue Cai, Xiwen Yang, Changjuan Jin, Lei Li, Qing Cui, Yijun Guo, Yun Dong, Xiaohua Yang, Lili Guo, Ming Zhang
Pages: 3642-3650
Published online on: 04 July 2018

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Itraconazole inhibits the proliferation of gastric cancer cells in vitro and improves patient survival

Ke Lan, Ron Yan, Kun Zhu, Wenhan Li, Zisen Xu, Chengxue Dang, Kang Li
Pages: 3651-3657
Published online on: 04 July 2018

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Downregulation of trefoil factor‑3 expression in the rectum is associated with the development of ulcerative colitis‑associated cancer

Satoru Kondo, Toshimitsu Araki, Yuji Toiyama, Koji Tanaka, Mikio Kawamura, Yoshinaga Okugawa, Yoshiki Okita, Susumu Saigusa, Yasuhiro Inoue, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
Pages: 3658-3664
Published online on: 10 July 2018

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Prognostic impact of SET domain‑containing protein 8 and protein arginine methyltransferase 5 in patients with hepatocellular carcinoma following curative resection

Zhifei Lin, Huliang Jia, Liang Hong, Yahui Zheng, Weiqin Shao, Xudong Ren, Wenwei Zhu, Lu Lu, Ming Lu, Jubo Zhang, Jinhong Chen
Pages: 3665-3673
Published online on: 05 July 2018

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Article Open Access

Cetuximab retreatment in patients with metastatic colorectal cancer who exhibited a clinical benefit in response to prior cetuximab: A retrospective study

Hiroaki Tanioka, Motoi Asano, Ryousuke Yoshida, Naohisa Waki, Futoshi Uno, Masahiro Ishizaki, Kazuki Yamashita, Yuki Morishita, Takeshi Nagasaka
Pages: 3674-3680
Published online on: 11 July 2018

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Article Open Access

Decreased CRHBP expression is predictive of poor prognosis in patients with hepatocellular carcinoma

Hai‑Bing Xia, Hui‑Ju Wang, Luo‑Qin Fu, Shi‑Bing Wang, Li Li, Guo‑Qing Ru, Xiang‑Lei He, Xiang‑Min Tong, Xiao‑Zhou Mou, Dong‑Sheng Huang
Pages: 3681-3689
Published online on: 04 July 2018

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Article Open Access

Comparative analysis of tumor‑associated vascular changes following TACE alone or in combination with sorafenib treatment in HCC: A retrospective study

Ligang Chen, Yifei Zheng, Hongjian Zhang, Heng Pan, Qiusong Liu, Xu Zhou, Wei Wei, Yun Liu, Maochuan Zhen, Jinling Wang, Jianyin Zhou, Yilin Zhao
Pages: 3690-3698
Published online on: 02 July 2018

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Association between AKT rs2494752 single nucleotide polymorphism and the risk of metastasis in hepatocellular carcinoma

Zhaohui Wang, Huiling Fu, Wei Li
Pages: 3699-3705
Published online on: 02 July 2018

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Article Open Access

si‑TP73‑AS1 suppressed proliferation and increased the chemotherapeutic response of GC cells to cisplatin

Jianjun Peng
Pages: 3706-3714
Published online on: 10 July 2018

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Article Open Access

Preliminary screening and analysis of metastasis‑related lncRNA and co‑expressed papillary thyroid carcinoma mRNA

Ming‑Hua Ge, Lie‑Hao Jiang, Qing‑Liang Wen, Zhuo Tan, Chao Chen, Chuan‑Ming Zheng, Xin Zhu, Jia‑Wen Chen, Zi‑Yu Zhu, Xiu‑Jun Cai
Pages: 3715-3725
Published online on: 05 July 2018

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Article Open Access

Circulating HER‑2 mRNA in the peripheral blood as a potential diagnostic and prognostic biomarker in females with breast cancer

Yanlin Wu, Qiping Meng, Zhixue Yang, Lili Shi, Rongkuan Hu, Peizhuo Zhang, Jinrong Wei, Jie Ren, Bingjing Leng, Dong Xu, Guo‑Qin Jiang
Pages: 3726-3734
Published online on: 05 July 2018

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Article Open Access

LncRNAs KB‑1836B5, LINC00566 and FAM27L are associated with the survival time of patients with ovarian cancer

Huijian Li, Mi Gong, Min Zhao, Xinru Wang, Wenjun Cheng, Yankai Xia
Pages: 3735-3745
Published online on: 12 July 2018

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Article Open Access

Prognostic value of heterogeneous ribonucleoprotein A1 expression and inflammatory indicators for patients with surgically resected hepatocellular carcinoma: Perspectives from a high occurrence area of hepatocellular carcinoma in China Erratum in /10.3892/ol.2018.9580

Ruisheng Ke, Lizhi Lv, Jiayan Li, Xiaojin Zhang, Fang Yang, Kun Zhang, Yi Jiang
Pages: 3746-3756
Published online on: 04 July 2018

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[Experts' Opinion] Novel formulations of docetaxel, paclitaxel and doxorubicin in the management of metastatic breast cancer

Senthil Rajappa, Ashish Joshi, Dinesh C. Doval, Ullas Batra, Rejiv Rajendranath, Avinash Deo, Ghanshyam Biswas, Peush Bajpai, T. V.S. Tilak, Sriram Kane, Kishore Kumar, Manish Kumar, Avinash D. Talele, Prakash Devde, Ashutosh Gupta, Nisarg Joshi, Jaykumar Sejpal, Deepak Bunger, Mujtaba Khan
Pages: 3757-3769
Published online on: 02 July 2018

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Article Open Access

Diagnostic accuracy of the UBC® Rapid Test for bladder cancer: A meta‑analysis

Pei Lu, Jianchun Cui, Keliang Chen, Qiang Lu, Jiexiu Zhang, Jun Tao, Zhijian Han, Wei Zhang, Rijin Song, Min Gu
Pages: 3770-3778
Published online on: 05 July 2018

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Article Open Access

Mechanism of the enhancing effects of miR‑93 on resistance of breast cancer MCF‑7 cells to adriamycin

Qian Wang, Chunying Su, Jiantao Li, Changsheng Wei
Pages: 3779-3783
Published online on: 29 June 2018

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Article Open Access

Endoglin‑targeted contrast‑enhanced ultrasound imaging in hepatoblastoma xenografts

Rong Shan, Bei Wang, Aiguang Wang, Zongguo Sun, Fengyun Dong, Ju Liu, Hongjun Sun
Pages: 3784-3790
Published online on: 04 July 2018

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Article Open Access

Expression of KIAA1456 in lung cancer tissue and its effects on proliferation, migration and invasion of lung cancer cells

Shuling Wang, Xiangqun Liu, Jianan Huang, Ying Zhang, Chunli Sang, Tao Li, Jieqing Yuan
Pages: 3791-3795
Published online on: 10 July 2018

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Article Open Access

Overexpression of SMARCA2 or CAMK2D is associated with cisplatin resistance in human epithelial ovarian cancer

Xiaoli Xu, Zhiguo Zheng, Lanlan Jia, Shasha Suo, Bowen Liu, Tianning Shao, Qinqing Tu, Yuejin Hua, Hong Xu
Pages: 3796-3804
Published online on: 10 July 2018

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Article Open Access

Clinical significance of decreased programmed cell death 4 expression in patients with giant cell tumors of the bone

Fei Gao, Wei Zhang, Lingling Ding, Miaoqing Zhao, Zhe Ma, Shanying Huang
Pages: 3805-3811
Published online on: 05 July 2018

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Article Open Access

Dual effects of arsenic trioxide on tumor cells and the potential underlying mechanisms

Xiao Zhang, Dahai Yu, Huaize Geng, Fengmei Li, Lin Lv, Lei Zhao, Caichuan Yan, Baoxin Li
Pages: 3812-3820
Published online on: 05 July 2018

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A study on the biological function of heat shock factor 1 proteins in breast cancer

Xiaolan Wang, Dianlong Zhang, Mingqian Cao, Jinling Ba, Bin Wu, Tao Liu, Chen Nie
Pages: 3821-3825
Published online on: 02 July 2018

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Article Open Access

Bufalin induced apoptosis of bladder carcinoma cells through the inactivation of Na+K+‑ATPase

Houbao Huang, Wei Zhang
Pages: 3826-3832
Published online on: 12 July 2018

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Article Open Access

Genetic variations in the SULF1 gene alter the risk of cervical cancer and precancerous lesions

Efthimios Dardiotis, Vasileios Siokas, Antonios Garas, Evangelos Paraskevaidis, Maria Kyrgiou, Georgia Xiromerisiou, Efthimios Deligeoroglou, Georgios Galazios, Emmanuel N. Kontomanolis, Demetrios A. Spandidos, Aristidis Tsatsakis, Alexandros Daponte
Pages: 3833-3841
Published online on: 06 July 2018

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Article Open Access

CREB1, a direct target of miR-122, promotes cell proliferation and invasion in bladder cancer

Lihua Guo, Min Yin, Yixuan Wang
Pages: 3842-3848
Published online on: 10 July 2018

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Article Open Access

Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin increases the activation of aryl hydrocarbon receptor and is associated with the aggressiveness of osteosarcoma MG-63 osteoblast-like cells

Shih-Chieh Yang, Chin-Hsien Wu, Yuan-Kun Tu, Shin-Yu Huang, Pai-Chien Chou
Pages: 3849-3857
Published online on: 06 July 2018

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Bleomycin inhibits proliferation and induces apoptosis in TPC‑1 cells through reversing M2‑macrophages polarization

Hongwei Liu, Huilei Dong, Li Jiang, Zhendong Li, Xiande Ma
Pages: 3858-3866
Published online on: 06 July 2018

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Article Open Access

Bufalin suppresses the proliferation and metastasis of renal cell carcinoma by inhibiting the PI3K/Akt/mTOR signaling pathway

Jinlin Xie, Wenfeng Lin, Linglong Huang, Naijin Xu, Abai Xu, Binshen Chen, Masami Watanabe, Chunxiao Liu, Peng Huang
Pages: 3867-3873
Published online on: 10 July 2018

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Article

Suppression of Hiwi inhibits the growth and epithelial‑mesenchymal transition of cervical cancer cells

Guangjun Pei, Baojian Li, Anjun Ma
Pages: 3874-3880
Published online on: 02 July 2018

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Article

Irreversible electroporation of malignant liver tumors: Effect on laboratory values

Mohammed Alnaggar, Ammar M. Qaid, Jibing Chen, Lizhi Niu, Kecheng Xu
Pages: 3881-3888
Published online on: 02 July 2018

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Case Report

Low‑grade myofibroblastic sarcoma arising in the tip of the tongue with intravascular invasion: A case report

Yurie Mikami, Shinsuke Fujii, Ken‑Ichi Kohashi, Yuichi Yamada, Masafumi Moriyama, Shintaro Kawano, Seiji Nakamura, Yoshinao Oda, Tamotsu Kiyoshima
Pages: 3889-3894
Published online on: 10 July 2018

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Article Open Access

Neoangiogenesis of gastric submucosa‑invasive adenocarcinoma

Hanae Sasaki, Satoko Morohashi, Takahito Toba, Hiroko Seino, Tadashi Yoshizawa, Hideaki Hirai, Toshihiro Haga, Yunyan Wu, Hiroshi Kijima
Pages: 3895-3900
Published online on: 10 July 2018

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Article

Astragaloside attenuates the progression of prostate cancer cells through endoplasmic reticulum stress pathways

Bo Tan, Renfeng Jia, Gang Wang, Jinhui Yang
Pages: 3901-3906
Published online on: 04 July 2018

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Article

LncRNA ATB promotes the proliferation and metastasis of lung cancer via activation of the p38 signaling pathway

Lei Wei, Tao Wu, Ping He, Jun‑Lei Zhang, Wei Wu
Pages: 3907-3912
Published online on: 10 July 2018

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Case Report

Identification of a novel breast cancer‑causing mutation in the BRCA1 gene by targeted next generation sequencing: A case report

Yanyan Wang, Da Jiang, Qiang Zhao, Hui Huang, Xue Zhang, Yanzhi Cui, Jiayin Liu, Jing Wu, Keke Lin, Weixi Chen, Jiale Xiang, Hui Jin, Zhiyu Peng, Santasree Banerjee
Pages: 3913-3916
Published online on: 12 July 2018

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Article

Distribution of circulating follicular helper T cells and expression of interleukin‑21 and chemokine C‑X‑C ligand 13 in gastric cancer

Xinying Meng, Xinjuan Yu, Quanjiang Dong, Xiaona Xu, Jinghua Li, Qianqian Xu, Jian Ma, Changhong Zhou
Pages: 3917-3922
Published online on: 10 July 2018

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Article

HIV positivity may not have a negative impact on survival in Epstein‑Barr virus‑positive Hodgkin lymphoma: A Japanese nationwide retrospective survey

Mihoko Yotsumoto, Yoshikazu Ito, Shotaro Hagiwara, Yasuhito Terui, Hirokazu Nagai, Yasunori Ota, Atsushi Ajisawa, Tomoko Uehira, Junko Tanuma, Kazuma Ohyashiki, Seiji Okada
Pages: 3923-3928
Published online on: 11 July 2018

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Article

Triptolide induces protective autophagy and apoptosis in human cervical cancer cells by downregulating Akt/mTOR activation

Guangyi Qin, Ping Li, Zhuowei Xue
Pages: 3929-3934
Published online on: 04 July 2018

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Article

LncRNA‑ECM is overexpressed in esophageal squamous cell carcinoma and promotes tumor metastasis

Juan Yao, Xiaozhou Shen, Hongzhi Li, Jie Xu, Shanshan Shao, Jun‑Xing Huang, Mei Lin
Pages: 3935-3942
Published online on: 11 July 2018

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Article Open Access

Mn12Ac inhibits the migration, invasion and epithelial‑mesenchymal transition of lung cancer cells by downregulating the Wnt/β‑catenin and PI3K/AKT signaling pathways

Zihao Chen, Jiangbo He, Xiqian Xing, Ping Li, Wei Zhang, Zhuxiu Tong, Xiaojie Jing, Licheng Li, Dian Liu, Qiong Wu, Hongping Ju
Pages: 3943-3948
Published online on: 11 July 2018

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Article

Role of YAP in lung cancer resistance to cisplatin

Juan Song, Li‑Xia Xie, Xin‑Yi Zhang, Ping Hu, Mei‑Fang Long, Fang Xiong, Juan Huang, Xiao‑Qun Ye
Pages: 3949-3954
Published online on: 12 July 2018

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Article

Function of GCN5 in the TGF‑β1‑induced epithelial‑to‑mesenchymal transition in breast cancer

Liming Zhao, Aixia Pang, Yunchun Li
Pages: 3955-3963
Published online on: 11 July 2018

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Article

Upregulation of gastric adenocarcinoma predictive long intergenic non‑coding RNA promotes progression and predicts poor prognosis in perihilar cholangiocarcinoma

Xin‑Ping Wang, Jing Song, Gui‑Ting Liu, Jian‑Jun Wang, Hai‑Feng Guo
Pages: 3964-3972
Published online on: 11 July 2018

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Case Report

Squamous cell carcinoma of the spleen: A case report

Zhou Jiang, Fang Ma, Xianling Liu
Pages: 3973-3975
Published online on: 06 July 2018

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Article

Targeting CXC motif chemokine receptor 4 inhibits the proliferation, migration and angiogenesis of lung cancer cells

Wei He, Tong Yang, Xin‑Hua Gong, Ru‑Zhai Qin, Xiao‑Dong Zhang, Wen‑Dan Liu
Pages: 3976-3982
Published online on: 04 July 2018

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Article

Silencing of uPAR via RNA interference inhibits invasion and migration of oral tongue squamous cell carcinoma

Xuexiang Gao, Qi Guo, Shuo Wang, Cen Gao, Jian Chen, Li Zhang, Yuan Zhao, Jing Wang
Pages: 3983-3991
Published online on: 06 July 2018

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Article

Dissecting the expression landscape of mitochondrial genes in lung squamous cell carcinoma and lung adenocarcinoma

Nan Li, Jing Zhao, Yibing Ma, Bhaskar Roy, Ren Liu, Karsten Kristiansen, Qiang Gao
Pages: 3992-4000
Published online on: 10 July 2018

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Article

The diagnostic and prognostic value of plasma microRNA‑125b‑5p in patients with multiple myeloma

Yanxia Jiang, Yajing Luan, Hong Chang, Guoan Chen
Pages: 4001-4007
Published online on: 11 July 2018

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Article

Effect of As2O3 on colorectal CSCs stained with ALDH1 in primary cell culture in vitro

Ke Ning, Wenlong Ning, Xiaoting Ning, Xueyan Wang, Fei Zhou
Pages: 4008-4012
Published online on: 10 July 2018

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Article

HMGN5 promotes proliferation and invasion via the activation of Wnt/β-catenin signaling pathway in pancreatic ductal adenocarcinoma

Jianwen Zhao, Yong Wang, Xinglong Wu
Pages: 4013-4019
Published online on: 05 July 2018

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Article

MicroRNA‑96 expression induced by low‑dose cisplatin or doxorubicin regulates chemosensitivity, cell death and proliferation in gastric cancer SGC7901 cells by targeting FOXO1

Chunhui Lang, Miao Xu, Ziyi Zhao, Jinyao Chen, Lishi Zhang
Pages: 4020-4026
Published online on: 11 July 2018

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Article

Establishment of an miR‑137‑knockout cell model using CRISPR/Cas9 genome editing

Wei Chen, Qi Li, Jingjie Du, Xiaodi Li, Songshan Jiang, Yuanli He
Pages: 4027-4032
Published online on: 06 July 2018

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Article

Combined effects of octreotide and cisplatin on the proliferation of side population cells from anaplastic thyroid cancer cell lines

Zhilan Li, Xiudi Jiang, Peihong Chen, Xuebing Wu, Aihua Duan, Yiyu Qin
Pages: 4033-4042
Published online on: 10 July 2018

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Case Report

Chronic active hepatitis induced by Pazopanib mimicking hypervascular liver metastases in a patient with recurrent soft tissue sarcoma: A case report

Ana Ezponda, Ignacio González De La Huebra, Marta Calvo, Miguel Ángel Idoate, Isabel Vivas
Pages: 4043-4048
Published online on: 10 July 2018

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Article

Optimal body mass index cut‑point for predicting recurrence‑free survival in patients with non‑muscle‑invasive urothelial carcinoma of bladder

Satoru Yonekura, Fumihito Terauchi, Kenji Hoshi, Takehiko Yamaguchi, Shigeo Kawai
Pages: 4049-4056
Published online on: 04 July 2018

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Article

Ulinastatin protects the lungs of COPD rats through the HMGB1/TLR4 signaling pathway

Wei Liu, Zhiguang Liu, Weidong Zhang, Shaoxi Cai
Pages: 4057-4063
Published online on: 11 July 2018

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Article

Proteins involved in cutaneous basal cell carcinoma development

Magdalena Ciążyńska, Igor A. Bednarski, Karolina Wódz, Paweł Kolano, Joanna Narbutt, Michał Sobjanek, Anna Woźniacka, Aleksandra Lesiak
Pages: 4064-4072
Published online on: 11 July 2018

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Article

PARP9 is overexpressed in human breast cancer and promotes cancer cell migration

Xinghong Tang, Hongying Zhang, Yan Long, Hui Hua, Yangfu Jiang, Jing Jing
Pages: 4073-4077
Published online on: 11 July 2018

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Article

Circular RNA as a biomarker for cancer: A systematic meta‑analysis

Yulong Li, Xiaoli Zeng, Jianxun He, Yuan Gui, Song Zhao, Hua Chen, Qi Sun, Nan Jia, Hui Yuan
Pages: 4078-4084
Published online on: 11 July 2018

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Case Report

Concurrent palliative external radiotherapy with sorafenib or doxorubicin for bulky differentiated thyroid carcinoma: A case report

Karen S. Cortés‑Mateus, Katarzyna Holub, Fabricio Racca, Juan José Grau, Jaume Capdevila
Pages: 4085-4089
Published online on: 04 July 2018

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June-2026 Volume 31 Issue 6

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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Article Open Access

METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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