|
1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Chen W, Zheng R, Zeng H, Zhang S and He J:
Annual report on status of cancer in China, 2011. Chin J Cancer
Res. 27:2–12. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
von Euler US: On the specific
vaso-dilating and plain muscle stimulating substances from
accessory genital glands in man and certain animals (prostaglandin
and vesiglandin). J Physiol. 88:213–234. 1936. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Legler DF, Bruckner M, Uetz-von Allmen E
and Krause P: Prostaglandin E2 at new glance: Novel insights in
functional diversity offer therapeutic chances. Int J Biochem Cell
Biol. 42:198–201. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Che Q, Liu BY, Liao Y, Zhang HJ, Yang TT,
He YY, Xia YH, Lu W, He XY, Chen Z, et al: Activation of a positive
feedback loop involving IL-6 and aromatase promotes intratumoral
17β-estradiol biosynthesis in endometrial carcinoma
microenvironment. Int J Cancer. 135:282–294. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Zhu M, Che Q, Liao Y, Wang H, Wang J, Chen
Z, Wang F, Dai C and Wan X: Oncostatin M activates STAT3 to promote
endometrial cancer invasion and angiogenesis. Oncol Rep.
34:129–138. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Doherty GA, Byrne SM, Molloy ES, Malhotra
V, Austin SC, Kay EW, Murray FE and Fitzgerald DJ: Proneoplastic
effects of PGE2 mediated by EP4 receptor in colorectal cancer. BMC
Cancer. 9:2072009. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Frasor J, Weaver AE, Pradhan M and Mehta
K: Synergistic up-regulation of prostaglandin E synthase expression
in breast cancer cells by 17beta-estradiol and proinflammatory
cytokines. Endocrinology. 149:6272–6279. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Rask K, Zhu Y, Wang W, Hedin L and
Sundfeldt K: Ovarian epithelial cancer: A role for PGE2-synthesis
and signalling in malignant transformation and progression. Mol
Cancer. 5:622006. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Yu H, Lee H, Herrmann A, Buettner R and
Jove R: Revisiting STAT3 signalling in cancer: New and unexpected
biological functions. Nat Rev Cancer. 14:736–746. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Frank DA: STAT3 as a central mediator of
neoplastic cellular transformation. Cancer Lett. 251:199–210. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Chaluvally-Raghavan P, Jeong KJ, Pradeep
S, Silva AM, Yu S, Liu W, Moss T, Rodriguez-Aguayo C, Zhang D, Ram
P, et al: Direct upregulation of STAT3 by MicroRNA-551b-3p
deregulates growth and metastasis of ovarian cancer. Cell Rep.
15:1493–1504. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Banerjee K and Resat H: Constitutive
activation of STAT3 in breast cancer cells: A review. Int J Cancer.
138:2570–2578. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Mora LB, Buettner R, Seigne J, Diaz J,
Ahmad N, Garcia R, Bowman T, Falcone R, Fairclough R, Cantor A, et
al: Constitutive activation of Stat3 in human prostate tumors and
cell lines: Direct inhibition of Stat3 signaling induces apoptosis
of prostate cancer cells. Cancer Res. 62:6659–6666. 2002.PubMed/NCBI
|
|
16
|
Luwor RB, Stylli SS and Kaye AH: The role
of Stat3 in glioblastoma multiforme. J Clin Neurosci. 20:907–911.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Pilati C and Zucman-Rossi J: Mutations
leading to constitutive active gp130/JAK1/STAT3 pathway. Cytokine
Growth Factor Rev. 26:499–506. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Guengerich FP: Cytochrome p450 and
chemical toxicology. Chem Res Toxicol. 21:70–83. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Vasaitis TS, Bruno RD and Njar VC: CYP17
inhibitors for prostate cancer therapy. J Steroid Biochem Mol Biol.
125:23–31. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Alex AB, Pal SK and Agarwal N: CYP17
inhibitors in prostate cancer: Latest evidence and clinical
potential. Ther Adv Med Oncol. 8:267–275. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Koh WJ, Greer BE, Abu-Rustum NR, Apte SM,
Campos SM, Chan J, Cho KR, Cohn D, Crispens MA, Dupont N, et al:
Uterine neoplasms, version 1.2014. J Natl Compr Canc Netw.
12:248–280. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Venturin GL, Chiku VM, Silva KL, de
Almeida BF and de Lima VM: M1 polarization and the effect of PGE2
on TNF-α production by lymph node cells from dogs with visceral
leishmaniasis. Parasite Immunol. 38:698–704. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Prosperi JR and Robertson FM:
Cyclooxygenase-2 directly regulates gene expression of P450 Cyp19
aromatase promoter regions pII, pI.3 and pI.7 and estradiol
production in human breast tumor cells. Prostaglandins Other Lipid
Mediat. 81:55–70. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Huang X, Jin J, Shen S, Xia Y, Xu P, Zou
X, Wang H, Yi L, Wang Y and Gao Q: Modulation of expression of
17-Hydroxylase/17,20 lyase (CYP17) and P450 aromatase (CYP19) by
inhibition of MEK1 in a human ovarian granulosa-like tumor cell
line. Gynecol Endocrinol. 32:201–205. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ramalho TR, Filgueiras LR, Pacheco de
Oliveira MT, Lima AL, Bezerra-Santos CR, Jancar S and Piuvezam MR:
Gamma-terpinene modulation of LPS-stimulated macrophages is
dependent on the PGE2/IL-10 axis. Planta Med. 82:1341–1345. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Machado-Carvalho L, Martín M, Torres R,
Gabasa M, Alobid I, Mullol J, Pujols L, Roca-Ferrer J and Picado C:
Low E-prostanoid 2 receptor levels and deficient induction of the
IL-1β/IL-1 type I receptor/COX-2 pathway: Vicious circle in
patients with aspirin-exacerbated respiratory disease. J Allergy
Clin Immunol. 137:99–107.e7. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Ke J, Yang Y, Che Q, Jiang F, Wang H, Chen
Z, Zhu M, Tong H, Zhang H, Yan X, et al: Prostaglandin E2 (PGE2)
promotes proliferation and invasion by enhancing SUMO-1 activity
via EP4 receptor in endometrial cancer. Tumour Biol.
37:12203–12211. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Mantovani A, Allavena P, Sica A and
Balkwill F: Cancer-related inflammation. Nature. 454:436–444. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: The next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Kim JI, Lakshmikanthan V, Frilot N and
Daaka Y: Prostaglandin E2 promotes lung cancer cell migration via
EP4-betaArrestin1-c-Src signalsome. Mol Cancer Res. 8:569–577.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Li S, Xu X, Jiang M, Bi Y, Xu J and Han M:
Lipopolysaccharide induces inflammation and facilitates lung
metastasis in a breast cancer model via the prostaglandin E2-EP2
pathway. Mol Med Rep. 11:4454–4462. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Miller WR, Anderson TJ and Jack WJ:
Relationship between tumour aromatase activity, tumour
characteristics and response to therapy. J Steroid Biochem Mol
Biol. 37:1055–1059. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Ito K, Miki Y, Suzuki T, McNamara KM and
Sasano H: In situ androgen and estrogen biosynthesis in endometrial
cancer: Focus on androgen actions and intratumoral production.
Endocr Relat Cancer. 23:R323–R335. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Goodman NF, Cobin RH, Futterweit W, Glueck
JS, Legro RS and Carmina E; American Association of Clinical
Endocrinologists (AACE), ; American College of Endocrinology (ACE),
; Androgen Excess and PCOS Society (AES), : American association of
clinical endocrinologists, american college of endocrinology and
androgen excess and pcos society disease state clinical review:
Guide to the best practices in the evaluation and treatment of
polycystic ovary syndrome-part 1. Endocr Pract. 21:1291–1300. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Shao R, Li X and Billig H: Promising
clinical practices of metformin in women with PCOS and early-stage
endometrial cancer. BBA Clin. 2:7–9. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Gao SP, Mark KG, Leslie K, Pao W, Motoi N,
Gerald WL, Travis WD, Bornmann W, Veach D, Clarkson B and Bromberg
JF: Mutations in the EGFR kinase domain mediate STAT3 activation
via IL-6 production in human lung adenocarcinomas. J Clin Invest.
117:3846–3856. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
38
|
Berishaj M, Gao SP, Ahmed S, Leslie K,
Al-Ahmadie H, Gerald WL, Bornmann W and Bromberg JF: Stat3 is
tyrosine-phosphorylated through the interleukin-6/glycoprotein
130/Janus kinase pathway in breast cancer. Breast Cancer Res.
9:R322007. View
Article : Google Scholar : PubMed/NCBI
|
|
39
|
Sai K, Wang S, Balasubramaniyan V, Conrad
C, Lang FF, Aldape K, Szymanski S, Fokt I, Dasgupta A, Madden T, et
al: Induction of cell-cycle arrest and apoptosis in glioblastoma
stem-like cells by WP1193, a novel small molecule inhibitor of the
JAK2/STAT3 pathway. J Neurooncol. 107:487–501. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Okazaki H, Tokumaru S, Hanakawa Y,
Shiraishi K, Shirakata Y, Dai X, Yang L, Tohyama M, Hashimoto K and
Sayama K: Nuclear translocation of phosphorylated STAT3 regulates
VEGF-A-induced lymphatic endothelial cell migration and tube
formation. Biochem Biophys Res Commun. 412:441–445. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Xie TX, Wei D, Liu M, Gao AC, Ali-Osman F,
Sawaya R and Huang S: Stat3 activation regulates the expression of
matrix metalloproteinase-2 and tumor invasion and metastasis.
Oncogene. 23:3550–3560. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Song Y, Qian L, Song S, Chen L, Zhang Y,
Yuan G, Zhang H, Xia Q, Hu M, Yu M, et al: Fra-1 and Stat3
synergistically regulate activation of human MMP-9 gene. Mol
Immunol. 45:137–143. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Subramaniam KS, Omar IS, Kwong SC, Mohamed
Z, Woo YL, Mat Adenan NA and Chung I: Cancer-associated fibroblasts
promote endometrial cancer growth via activation of
interleukin-6/STAT-3/c-Myc pathway. Am J Cancer Res. 6:200–213.
2016.PubMed/NCBI
|
|
44
|
Gao J, Tian J, Lv Y, Shi F, Kong F, Shi H
and Zhao L: Leptin induces functional activation of
cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT
pathways in human endometrial cancer cells. Cancer Sci.
100:389–395. 2009. View Article : Google Scholar : PubMed/NCBI
|
