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Article

Neurological manifestations of atrial myxoma: A retrospective analysis

  • Authors:
    • Xue‑Yan Wen
    • Yong‑Min Chen
    • Li‑Li Yu
    • Shu‑Rong Wang
    • Hong‑Bo Zheng
    • Zhi‑Bin Chen
    • Lin Ma
    • Xiao‑Ping Liao
    • Qi‑Fu Li
  • View Affiliations / Copyright

    Affiliations: Department of Neurology, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan 571199, P.R. China, Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
  • Pages: 4635-4639
    |
    Published online on: July 25, 2018
       https://doi.org/10.3892/ol.2018.9218
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Abstract

Atrial myxoma is the most common type of primary cardiac tumor and it is closely associated with stroke in adults. Early diagnosis and treatment of atrial myxomas is essential for the prevention of embolic events. The aim of the present study was to assess neurological complications associated with atrial myxoma. The neurological signs of atrial myxoma were retrospectively assessed in individuals who underwent treatment at West China Hospital (Chengdu, China) and The Affiliated Hospital of Hainan Medical University (Haikou, China), between March 2003 and February 2015. A total of 130 patients with atrial myxoma were included and 22 (17%) exhibited neurologic signs. These patients were aged 39.9±12.6 years (range, 13‑78 years) and there were 13 female and 9 male patients. Ischemic cerebral infarct constituted the dominant clinical symptom (68.2%) and 3 patients exhibited concomitant cardiac manifestations. Atrial myxoma was diagnosed by echocardiography in all patients. Irregular surface of atrial myxomas was associated with a high risk of embolic events. The patients with myxoma successfully underwent surgery with no mortality recorded. In conclusion, atrial myxomas frequently manifest as cerebral infarction in individuals without cardiovascular risk factors. These tumors more commonly affect the middle cerebral artery. Irregular surface of myxomas appears to be associated with embolic events. Echocardiography may improve the diagnosis and early treatment of atrial myxomas.
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Copy and paste a formatted citation
Spandidos Publications style
Wen XY, Chen YM, Yu LL, Wang SR, Zheng HB, Chen ZB, Ma L, Liao XP and Li QF: Neurological manifestations of atrial myxoma: A retrospective analysis. Oncol Lett 16: 4635-4639, 2018.
APA
Wen, X., Chen, Y., Yu, L., Wang, S., Zheng, H., Chen, Z. ... Li, Q. (2018). Neurological manifestations of atrial myxoma: A retrospective analysis. Oncology Letters, 16, 4635-4639. https://doi.org/10.3892/ol.2018.9218
MLA
Wen, X., Chen, Y., Yu, L., Wang, S., Zheng, H., Chen, Z., Ma, L., Liao, X., Li, Q."Neurological manifestations of atrial myxoma: A retrospective analysis". Oncology Letters 16.4 (2018): 4635-4639.
Chicago
Wen, X., Chen, Y., Yu, L., Wang, S., Zheng, H., Chen, Z., Ma, L., Liao, X., Li, Q."Neurological manifestations of atrial myxoma: A retrospective analysis". Oncology Letters 16, no. 4 (2018): 4635-4639. https://doi.org/10.3892/ol.2018.9218
Copy and paste a formatted citation
x
Spandidos Publications style
Wen XY, Chen YM, Yu LL, Wang SR, Zheng HB, Chen ZB, Ma L, Liao XP and Li QF: Neurological manifestations of atrial myxoma: A retrospective analysis. Oncol Lett 16: 4635-4639, 2018.
APA
Wen, X., Chen, Y., Yu, L., Wang, S., Zheng, H., Chen, Z. ... Li, Q. (2018). Neurological manifestations of atrial myxoma: A retrospective analysis. Oncology Letters, 16, 4635-4639. https://doi.org/10.3892/ol.2018.9218
MLA
Wen, X., Chen, Y., Yu, L., Wang, S., Zheng, H., Chen, Z., Ma, L., Liao, X., Li, Q."Neurological manifestations of atrial myxoma: A retrospective analysis". Oncology Letters 16.4 (2018): 4635-4639.
Chicago
Wen, X., Chen, Y., Yu, L., Wang, S., Zheng, H., Chen, Z., Ma, L., Liao, X., Li, Q."Neurological manifestations of atrial myxoma: A retrospective analysis". Oncology Letters 16, no. 4 (2018): 4635-4639. https://doi.org/10.3892/ol.2018.9218
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