|
1
|
Jemal A, Siegel R, Xu J and Ward E: Cancer
statistics, 2010. CA Cancer J Clin. 60:277–300. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Liu D, Yang Y and Zhao S: Autophagy
facilitates the EGFR-TKI acquired resistance of non-small-cell lung
cancer cells. J Formos Med Assoc. 113:141–142. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Petersen I and Petersen S: Towards a
genetic-based classification of human lung cancer. Anal Cell
Pathol. 22:111–121. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ma J, Ward EM, Smith R and Jemal A: Annual
number of lung cancer deaths potentially avertable by screening in
the united states. Cancer. 119:1381–1385. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Jones SE: Metastatic breast cancer: The
treatment challenge. Clin Breast Cancer. 8:224–233. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Bacac M and Stamenkovic I: Metastatic
cancer cell. Annu Rev Pathol. 3:221–247. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Chaffer CL and Weinberg RA: A perspective
on cancer cell metastasis. Science. 331:1559–1564. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Thiery JP: Epithelial-mesenchymal
transitions in tumour progression. Nat Rev Cancer. 2:442–454. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Kalluri R and Weinberg RA: The basics of
epithelial-mesenchymal transition. J Clin Invest. 119:1420–1428.
2009. View
Article : Google Scholar : PubMed/NCBI
|
|
10
|
Tomaskovic-Crook E, Thompson EW and Thiery
JP: Epithelial to mesenchymal transition and breast cancer. Breast
Cancer Res. 11:2132009. View
Article : Google Scholar : PubMed/NCBI
|
|
11
|
Yilmaz M, Christofori G and Lehembre F:
Distinct mechanisms of tumor invasion and metastasis. Trends Mol
Med. 13:535–541. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Jarde T, Caldefie-Chezet F, Damez M,
Mishellany F, Penault-Llorca F, Guillot J and Vasson MP: Leptin and
leptin receptor involvement in cancer development: A study on human
primary breast carcinoma. Oncol Rep. 19:905–911. 2008.PubMed/NCBI
|
|
13
|
Liu CL, Chang YC, Cheng SP, Chern SR, Yang
TL, Lee JJ, Guo IC and Chen CP: The roles of serum leptin
concentration and polymorphism in leptin receptor gene at codon 109
in breast cancer. Oncology. 72:75–81. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Otvos L Jr and Surmacz E: Targeting the
leptin receptor: A potential new mode of treatment for breast
cancer. Expert Rev Anticancer Ther. 11:1147–1150. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Akinci M, Kosova F, Cetin B, Aslan S, Ari
Z and Cetin A: Leptin levels in thyroid cancer. Asian J Surg.
32:216–223. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Uddin S, Bu R, Ahmed M, Hussain AR, Ajarim
D, Al-Dayel F, Bavi P and Al-kuraya KS: Leptin receptor expression
and its association with pi3k/akt signaling pathway in diffuse
large b-cell lymphoma. Leuk Lymphoma. 51:1305–1314. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kitade M, Yoshiji H, Kojima H, Ikenaka Y,
Noguchi R, Kaji K, Yoshii J, Yanase K, Namisaki T, Asada K, et al:
Leptin-mediated neovascularization is a prerequisite for
progression of nonalcoholic steatohepatitis in rats. Hepatology.
44:983–991. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ribatti D, Belloni AS, Nico B, Di Comite
M, Crivellato E and Vacca A: Leptin-leptin receptor are involved in
angiogenesis in human hepatocellular carcinoma. Peptides.
29:1596–1602. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Chia VM, Newcomb PA, Lampe JW, White E,
Mandelson MT, McTiernan A and Potter JD: Leptin concentrations,
leptin receptor polymorphisms and colorectal adenoma risk. Cancer
Epidemiol Biomark Prev. 16:2697–2703. 2007. View Article : Google Scholar
|
|
20
|
Stolzenberg-Solomon RZ, Newton CC,
Silverman DT, Pollak M, Nogueira LM, Weinstein SJ, Albanes D,
Mannisto S and Jacobs EJ: Circulating leptin and risk of pancreatic
cancer: A pooled analysis from 3 cohorts. Am J Epidemiol.
182:187–197. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Feng H, Liu Q, Zhang N, Zheng L, Sang M,
Feng J, Zhang J, Wu X and Shan B: Leptin promotes metastasis by
inducing an epithelial-mesenchymal transition in a549 lung cancer
cells. Oncol Res. 21:165–171. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Kim JH, Jang YS, Eom KS, Hwang YI, Kang
HR, Jang SH, Kim CH, Park YB, Lee MG, Hyun IG, et al: Transforming
growth factor beta1 induces epithelial-to-mesenchymal transition of
a549 cells. J Korean Med Sci. 22:898–904. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kasai H, Allen JT, Mason RM, Kamimura T
and Zhang Z: TGF-beta1 induces human alveolar epithelial to
mesenchymal cell transition (EMT). Respir Res. 6:562005. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Zhang HJ, Wang HY, Zhang HT, Su JM, Zhu J,
Wang HB, Zhou WY, Zhang H, Zhao MC, Zhang L, et al: Transforming
growth factor-β1 promotes lung adenocarcinoma invasion and
metastasis by epithelial-to-mesenchymal transition. Mol Cell
Biochem. 355:309–314. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Malli F, Papaioannou AI, Gourgoulianis KI
and Daniil Z and Daniil Z: The role of leptin in the respiratory
system: An overview. Respir Res. 11:1522010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Lago F, Dieguez C, Gomez-Reino J and
Gualillo O: Adipokines as emerging mediators of immune response and
inflammation. Nat Clin Pract Rheumatol. 3:716–724. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Xu YJ, Shao YF, Zhao X, Geng YT, Wang K
and Yin YM: Expression and clinical significance of leptin, the
functional receptor of leptin (OB-Rb) and her-2 in non-small-cell
lung cancer: A retrospective analysis. J Cancer Res Clin Oncol.
137:1841–1848. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Li Y, Geng J, Wang Y, Lu Q, Du Y, Wang W
and Li Z: The role of leptin receptor gene polymorphisms in
determining the susceptibility and prognosis of nsclc in chinese
patients. J Cancer Res Clin Oncol. 138:311–316. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Wang W, Yan H, Dou C and Su Y: Human
leptin triggers proliferation of a549 cells via blocking
endoplasmic reticulum stress-related apoptosis. Biochemistry.
78:1333–1341. 2013.PubMed/NCBI
|
|
30
|
Shen Y, Wang Q, Zhao Q and Zhou J: Leptin
promotes the immune escape of lung cancer by inducing
proinflammatory cytokines and resistance to apoptosis. Mol Med Rep.
2:295–299. 2009.PubMed/NCBI
|
|
31
|
Lai Q and Sun Y: Human leptin protein
induces proliferation of A549 cells via inhibition of PKR-like ER
kinase and activating transcription factor-6 mediated apoptosis.
Yonsei Med J. 54:1407–1415. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zheng XJ, Yang ZX, Dong YJ, Zhang GY, Sun
MF, An XK, Pan LH and Zhang SL: Downregulation of leptin inhibits
growth and induces apoptosis of lung cancer cells via the notch and
jak/stat3 signaling pathways. Biol Open. 5:794–800. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Qi HW, Xin LY, Xu X, Ji XX and Fan LH:
Epithelial-to-mesenchymal transition markers to predict response of
berberine in suppressing lung cancer invasion and metastasis. J
Transl Med. 12:222014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Sanchez-Tillo E, Lazaro A, Torrent R,
Cuatrecasas M, Vaquero EC, Castells A, Engel P and Postigo A: Zeb1
represses e-cadherin and induces an emt by recruiting the swi/snf
chromatin-remodeling protein brg1. Oncogene. 29:3490–3500. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Yang MH, Hsu DS, Wang HW, Wang HJ, Lan HY,
Yang WH, Huang CH, Kao SY, Tzeng CH, Tai SK, et al: Bmi1 is
essential in Twist1-induced epithelial-mesenchymal transition. Nat
Cell Biol. 12:982–992. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Chen XF, Zhang HJ, Wang HB, Zhu J, Zhou
WY, Zhang H, Zhao MC, Su JM, Gao W, Zhang L, et al: Transforming
growth factor-β1 induces epithelial-to-mesenchymal transition in
human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling
pathways. Mol Biol Rep. 39:3549–3556. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Bakin AV, Tomlinson AK, Bhowmick NA, Moses
HL and Arteaga CL: Phosphatidylinositol 3-kinase function is
required for transforming growth factor beta-mediated epithelial to
mesenchymal transition and cell migration. J Biol Chem.
275:36803–36810. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Derynck R and Zhang YE: Smad-dependent and
smad-independent pathways in tgf-beta family signalling. Nature.
425:577–584. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Ahmad A, Maitah MY, Ginnebaugh KR, Li Y,
Bao B, Gadgeel SM and Sarkar FH: Inhibition of hedgehog signaling
sensitizes nsclc cells to standard therapies through modulation of
emt-regulating mirnas. J Hematol Oncol. 6:772013. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Gomes LR, Terra LF, Sogayar MC and
Labriola L: Epithelial-mesenchymal transition: Implications in
cancer progression and metastasis. Curr Pharm Biotechnol.
12:1881–1890. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Karatas F, Yalcin B, Sahin S, Akbulut H,
Utkan G, Demirkazik A and Icli F: The significance of serum leptin
level in patients with early stage nonsmall cell lung cancer. J
Cancer Res Ther. 13:204–207. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Tong X, Ma Y, Zhou Q, He J, Peng B, Liu S,
Yan Z, Yang X and Fan H: Serum and tissue leptin in lung cancer: A
meta-analysis. Oncotarget. 8:19699–19711. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Feng HL, Guo P, Wang J, Liu QY, Xu JF,
Yang HC and Zhang JM: Association of the expression of leptin and
leptin receptor with bone metastasis in pulmonary adenocarcinoma.
Zhonghua Zhong Liu Za Zhi. 38:840–844. 2016.(In Chinese).
PubMed/NCBI
|
|
44
|
Mou W, Xue H, Tong H, Sun S, Zhang Z,
Zhang C, Sun Q, Dong J, Wen X, Yan G, et al: Prognostic value of
serum leptin in advanced lung adenocarcinoma patients with
cisplatin/pemetrexed chemotherapy. Oncol Lett. 7:2073–2078. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Demiray G, Degirmencioglu S, Ugurlu E and
Yaren A: Effects of serum leptin and resistin levels on cancer
cachexia in patients with advanced-stage non-small cell lung
cancer. Clin Med Insights Oncol. 11:11795549176901442017.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Anar C, Deniz D, Erol S, Batum O, Bicmen C
and Yilmaz U: Are serum leptin levels a prognostic factor in
advanced lung cancer? Bratisl Lek Listy. 118:13–16. 2017.PubMed/NCBI
|
