1
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
2
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
3
|
Nur U, Quaresma M, De Stavola B, Peake M
and Rachet B: Inequalities in non-small cell lung cancer treatment
and mortality. J Epidemiol Community Health. 69:985–992. 2015.
View Article : Google Scholar : PubMed/NCBI
|
4
|
Molina JR, Yang P, Cassivi SD, Schild SE
and Adjei AA: Non-small cell lung cancer: Epidemiology, risk
factors, treatment, and survivorship. Mayo Clin Proc. 83:584–594.
2008. View Article : Google Scholar : PubMed/NCBI
|
5
|
Martin GS: The hunting of the Src. Nat Rev
Mol Cell Biol. 2:467–475. 2001. View
Article : Google Scholar : PubMed/NCBI
|
6
|
Mello AA, Leal MF, Rey JA, Pinto GR,
Lamarão LM, Montenegro RC, Alves AP, Assumpção PP, Borges Bdo N,
Smith MC and Burbano RR: Deregulated expression of SRC, LYN and CKB
Kinases by DNA methylation and its potential role in gastric cancer
invasiveness and metastasis. PLos One. 10:e01404922015. View Article : Google Scholar : PubMed/NCBI
|
7
|
Chen J, Elfiky A, Han M, Chen C and Saif
MW: The role of Src in colon cancer and its therapeutic
implications. Clin Colorectal Cancer. 13:5–13. 2014. View Article : Google Scholar : PubMed/NCBI
|
8
|
Nam K, Oh S, Lee KM, Yoo SA and Shin I:
CD44 regulates cell proliferation, migration, and invasion via
modulation of c-Src transcription in human breast cancer cells.
Cell Signal. 27:1882–1894. 2015. View Article : Google Scholar : PubMed/NCBI
|
9
|
Je DW, O YM, Ji YG, Cho Y and Lee DH: The
inhibition of SRC family kinase suppresses pancreatic cancer cell
proliferation, migration, and invasion. Pancreas. 43:768–776. 2014.
View Article : Google Scholar : PubMed/NCBI
|
10
|
Singh S, Trevino J, Bora-Singhal N,
Coppola D, Haura E, Altiok S and Chellappan SP: EGFR/Src/Akt
signaling modulates Sox2 expression and self-renewal of stem-like
side-population cells in non-small cell lung cancer. Mol Cancer.
11:732012. View Article : Google Scholar : PubMed/NCBI
|
11
|
Min HY, Yun HJ, Lee JS, Lee HJ, Cho J,
Jang HJ, Park SH, Liu D, Oh SH, Lee JJ, et al: Targeting the
insulin-like growth factor receptor and Src signaling network for
the treatment of non-small cell lung cancer. Mol Cancer.
14:1132015. View Article : Google Scholar : PubMed/NCBI
|
12
|
Sutton P, Borgia JA, Bonomi P and Plate
JM: Lyn, a Src family kinase, regulates activation of epidermal
growth factor receptors in lung adenocarcinoma cells. Mol Cancer.
12:762013. View Article : Google Scholar : PubMed/NCBI
|
13
|
Phuchareon J, McCormick F, Eisele DW and
Tetsu O: EGFR inhibition evokes innate drug resistance in lung
cancer cells by preventing Akt activity and thus inactivating Ets-1
function. Proc Natl Acad Sci USA. 112:E3855–E3863. 2015. View Article : Google Scholar : PubMed/NCBI
|
14
|
Shi Y: Mechanisms of caspase activation
and inhibition during apoptosis. Mol Cell. 9:459–470. 2002.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Joseph B, Ekedahl J, Lewensohn R,
Marchetti P, Formstecher P and Zhivotovsky B: Defective caspase-3
relocalization in non-small cell lung carcinoma. Oncogene.
20:2877–2888. 2001. View Article : Google Scholar : PubMed/NCBI
|
16
|
Fu YN, Yeh CL, Cheng HH, Yang CH, Tsai SF,
Huang SF and Chen YR: EGFR mutants found in non-small cell lung
cancer show different levels of sensitivity to suppression of Src:
Implications in targeting therapy. Oncogene. 27:957–965. 2008.
View Article : Google Scholar : PubMed/NCBI
|
17
|
Zeng H, Zheng R, Guo Y, Zhang S, Zou X,
Wang N, Zhang L, Tang J, Chen J, Wei K, et al: Cancer survival in
China, 2003–2005: A population-based study. Int J Cancer.
136:1921–1930. 2015. View Article : Google Scholar : PubMed/NCBI
|
18
|
Frame MC: Src in cancer: Deregulation and
consequences for cell behaviour. Biochim Biophys Acta.
1602:114–130. 2002.PubMed/NCBI
|
19
|
Nam JS, Ino Y, Sakamoto M and Hirohashi S:
Src family kinase inhibitor PP2 restores the E-cadherin/catenin
cell adhesion system in human cancer cells and reduces cancer
metastasis. Clin Cancer Res. 8:2430–2436. 2002.PubMed/NCBI
|
20
|
Biscardi JS, Maa MC, Tice DA, Cox ME, Leu
TH and Parsons SJ: C-Src-mediated phosphorylation of the epidermal
growth factor receptor on Tyr845 and Tyr1101 is associated with
modulation of receptor function. J Biol Chem. 274:8335–8343. 1999.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Sarris EG, Saif MW and Syrigos KN: The
biological role of PI3K pathway in lung cancer. Pharmaceuticals
(Basel). 5:1236–1264. 2012. View Article : Google Scholar : PubMed/NCBI
|
22
|
Engelman JA, Luo J and Cantley LC: The
evolution of phosphatidylinositol 3-kinases as regulators of growth
and metabolism. Nat Rev Genet. 7:606–619. 2006. View Article : Google Scholar : PubMed/NCBI
|
23
|
Tsurutani J, Fukuoka J, Tsurutani H, Shih
JH, Hewitt SM, Travis WD, Jen J and Dennis PA: Evaluation of two
phosphorylation sites improves the prognostic significance of Akt
activation in non-small-cell lung cancer tumors. J Clin Oncol.
24:306–314. 2006. View Article : Google Scholar : PubMed/NCBI
|
24
|
Bose P, Rahmani M and Grant S: Coordinate
PI3K pathway and Bcl-2 family disruption in AML. Oncotarget.
3:1499–1500. 2012. View Article : Google Scholar : PubMed/NCBI
|
25
|
Elmore S: Apoptosis: A review of
programmed cell death. Toxicol Pathol. 35:495–516. 2007. View Article : Google Scholar : PubMed/NCBI
|
26
|
Ahel I, Ahel D, Matsusaka T, Clark AJ,
Pines J, Boulton SJ and West SC: Poly(ADP-ribose)-binding zinc
finger motifs in DNA repair/checkpoint proteins. Nature. 451:81–85.
2008. View Article : Google Scholar : PubMed/NCBI
|
27
|
Enari M, Sakahira H, Yokoyama H, Okawa K,
Iwamatsu A and Nagata S: A caspase-activated DNase that degrades
DNA during apoptosis, and its inhibitor ICAD. Nature. 391:43–50.
1998. View Article : Google Scholar : PubMed/NCBI
|