|
1
|
May M: Statistics: Attacking an epidemic.
Nature. 509:50–51. 2014. View
Article : Google Scholar
|
|
2
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Zhou D, Yang L, Zheng L, Ge W, Li D, Zhang
Y, Hu X, Gao Z, Xu J, Huang Y, et al: Exome capture sequencing of
adenoma reveals Genetic alterations in multiple cellular pathways
at the early stage of colorectal tumorigenesis. PLoS One.
8:e533102013. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Korinek V, Barker N, Morin PJ, vanWichen
D, de Weger R, Kinzler KW, Vogelstein B and Clevers H: Constitutive
transcriptional activation by a β-catenin-Tcf complex in
APC−/− colon carcinoma. Science. 275:1784–1787. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Morin PJ, Sparks AB, Korinek V, Barker N,
Clevers H, Vogelstein B and Kinzler KW: Activation of
beta-catenin-Tcf signaling in colon cancer by mutations in
beta-catenin or APC. Science. 275:1787–1790. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Baker SJ, Markowitz S, Fearon ER, Willson
JK and Vogelstein B: Suppression of human colorectal carcinoma cell
growth by wild-type p53. Science. 249:912–915. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Aoki Y, Niihori T, Narumi Y, Kure S and
Matsubara Y: The RAS/MAPK syndromes: Novel roles of the RAS pathway
in human genetic disorders. Hum Muta. 29:992–1006. 2008. View Article : Google Scholar
|
|
8
|
Young LW, Darios ES and Watts SW: An
immunohistochemical analysis of SERT in the blood-brain barrier of
the male rat brain. Histochem Cell Biol. 144:321–329. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Stuart JN, Ebaugh JD, Copes AL, Hatcher
NG, Gillette R and Sweedler JV: Systemic serotonin sulfate in
opisthobranch mollusks. J Neurochem. 90:734–742. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Oh KH, Nam Y, Jeong JH, Kim IK and Sohn
UD: The effect of DA-9701 on 5-hydroxytryptamine-induced
contraction of feline esophageal smooth muscle cells. Molecules.
19:5135–5149. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Shyu KG: Serotonin 5-HT2B
receptor in cardiac fibroblast contributes to cardiac hypertrophy:
A new therapeutic target for heart failure? Circ Res. 104:1–3.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Davies PA, Pistis M, Hanna MC, Peters JA,
Lambert JJ, Hales TG and Kirkness EF: The 5-HT3B subunit
is a major determinant of serotonin-receptor function. Nature.
397:359–363. 1999. View
Article : Google Scholar : PubMed/NCBI
|
|
13
|
Amirabad Mohammadi L, Ahangari G and
Deilami Derakhshan G: Significant changes of 5-Hydroxytriptamine 3A
receptor gene expression in peripheral blood mononuclear cells of
allergic asthmatic patients. Iran J Allergy Asthma Immunol.
13:33–39. 2014.PubMed/NCBI
|
|
14
|
Lummis SC: 5-HT3 receptors. J
Biol Chem. 287:40239–40245. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Jansen M, Bali M and Akabas MH: Modular
design of Cys-loop ligand-gated ion channels: Functional
5-HT3 and GABA rho 1 receptors lacking the large
cytoplasmic M3M4 loop. J Gen Physiol. 131:137–146. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Dizeyi N, Bjartell A, Nilsson E, Hansson
J, Gadaleanu V, Cross N and Abrahamsson PA: Expression of serotonin
receptors and role of serotonin in human prostate cancer tissue and
cell lines. Prostate. 59:328–336. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Siddiqui EJ, Shabbir MA, Mikhailidis DP,
Mumtaz FH and Thompson CS: The effect of serotonin and serotonin
antagonists on bladder cancer cell proliferation. BJU Int.
97:634–639. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Sonier B, Arseneault M, Lavigne C,
Ouellette RJ and Vaillancourt C: The 5-HT2A serotoninergic receptor
is expressed in the MCF-7 human breast cancer cell line and reveals
a mitogenic effect of serotonin. Biochem Biophys Res Commun.
343:1053–1059. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Tutton PJ and Barkla DH: The influence of
serotonin on the mitotic rate in the colonic crypt epithelium and
in colonic adenocarcinoma in rats. Clin Exp Pharmacol Physiol.
5:91–94. 1978. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Ataee R, Ajdary S, Rezayat M, Shokrgozar
MA, Shahriari S and Zarrindast MR: Study of 5HT3 and HT4 receptor
expression in HT29 cell line and human colon adenocarcinoma
tissues. Arch Iran Med. 13:120–125. 2010.PubMed/NCBI
|
|
21
|
Rinaldi A, Chiaravalli AM, Mian M, Zucca
E, Tibiletti MG, Capella C and Bertoni F: Serotonin receptor 3A
expression in normal and neoplastic B cells. Pathobiology.
77:129–135. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Gaedcke J, Grade M, Jung K, Camps J, Jo P,
Emons G, Gehoff A, Sax U, Schirmer M, Becker H, et al: Mutated KRAS
results in overexpression of DUSP4, a MAP-kinase phosphatase, and
SMYD3, a histone methyltransferase, in rectal carcinomas. Genes
Chromosomes Cancer. 49:1024–1034. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Hong Y, Downey T, Eu KW, Koh PK and Cheah
PY: A ‘metastasis-prone’ signature for early-stage mismatch-repair
proficient sporadic colorectal cancer patients and its implications
for possible therapeutics. Clin Exp Metastasis. 27:83–90. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Notterman DA, Alon U, Sierk AJ and Levine
AJ: Transcriptional gene expression profiles of colorectal adenoma,
adenocarcinoma, and normal tissue examined by oligonucleotide
arrays. Cancer Res. 61:3124–3130. 2001.PubMed/NCBI
|
|
25
|
Sabates-Bellver J, van der Flier LG, de
Palo M, Cattaneo E, Maake C, Rehrauer H, Laczko E, Kurowski MA,
Bujnicki JM, Menigatti M, et al: Transcriptome profile of human
colorectal adenomas. Mol Cancer Res. 5:1263–1275. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2−ΔΔCT method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Park H, Oh CM, Park J, Park H, Cui S, Kim
HS, Namkung J, Park SK, Pak HN, Lee MH, et al: Deletion of the
serotonin receptor type 3A in mice leads to sudden cardiac death
during pregnancy. Circ J. 79:1807–1815. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Oh CM, Namkung J, Go Y, Shong KE, Kim K,
Kim H, Park BY, Lee HW, Jeon YH, Song J, et al: Regulation of
systemic energy homeostasis by serotonin in adipose tissues. Nat
Commun. 6:67942015. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Murthy S, Niquille M, Hurni N, Limoni G,
Frazer S, Chameau P, van Hooft JA, Vitalis T and Dayer A: Serotonin
receptor 3A controls interneuron migration into the neocortex. Nat
Commun. 5:55242014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Hanahan D and Weinberg R: Hallmarks of
cancer: The next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Malumbres M and Barbacid M: Cell cycle,
CDKs and cancer: A changing paradigm. Nat Rev Cancer. 9:153–166.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Kastan MB and Bartek J: Cell-cycle
checkpoints and cancer. Nature. 432:316–323. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Liu Y, Tian HY, Yan XL, Fan FL, Wang WP,
Han JL, Zhang JB, Ma Q, Meng Y and Wei F: Serotonin inhibits
apoptosis of pulmonary artery smooth muscle cell by pERK1/2 and PDK
through 5-HT 1B receptors and 5-HT transporters. Cardiovasc Pathol.
22:451–457. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Ataee R, Ajdary S, Zarrindast M, Rezayat M
and Hayatbakhsh MR: Anti-mitogenic and apoptotic effects of 5-HT1B
receptor antagonist on HT29 colorectal cancer cell line. J Cancer
Res Clin Oncol. 136:1461–1469. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Hejazi SH, Ahangari G and Deezagi A:
Alternative view point against breast cancer based on selective
serotonin receptors 5HTR3A and 5HTR2A antagonists that can mediate
apoptosis in MCF-7 cell line. Curr Drug Discov Technol. 12:240–249.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Ataee R, Ajdary S, Zarrindast M, Rezayat
M, Shokrgozar MA and Ataee A: Y25130 hydrochloride, a selective
5HT3 receptor antagonist has potent antimitogenic and apoptotic
effect on HT29 colorectal cancer cell line. Eur J Cancer Prev.
19:138–143. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Cory S, Huang DC and Adams JM: The Bcl-2
family: Roles in cell survival and oncogenesis. Oncogene.
22:8590–8607. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Story M and Kodym R: Signal transduction
during apoptosis; implications for cancer therapy. Front Biosci.
3:d365–d375. 1998. View
Article : Google Scholar : PubMed/NCBI
|
|
39
|
Cory S and Adams JM: The Bcl2 family:
Regulators of the cellular life-or-death switch. Nat Rev Cancer.
2:647–656. 2002. View
Article : Google Scholar : PubMed/NCBI
|
|
40
|
Johnston KD, Lu Z and Rudd JA: Looking
beyond 5-HT3 receptors: A review of the wider role of
serotonin in the pharmacology of nausea and vomiting. Eur J
Pharmacol. 722:13–25. 2014. View Article : Google Scholar : PubMed/NCBI
|
