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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2018 Volume 16 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Emerging function of N6‑methyladenosine in cancer (Review)

Kwonho Hong
Pages: 5519-5524
Published online on: 04 September 2018

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Article Open Access

Upregulation of stem cell markers ALDH1A1 and OCT4 as potential biomarkers for the early detection of cervical carcinoma

Wuniqiemu Tulake, Reziwanguli Yuemaier, Lei Sheng, Mingfang Ru, Dilare Lidifu, Abulizi Abudula
Pages: 5525-5534
Published online on: 03 September 2018

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Article Open Access

MicroRNA‑217 functions as a tumor suppressor in cervical cancer cells through targeting Rho‑associated protein kinase 1 Retraction in /10.3892/ol.2024.14657

Jing Dong, Maoxiu Wang, Donghua Ni, Lixin Zhang, Wen Wang, Xiujuan Cui, Shijie Fu, Shujuan Yao
Pages: 5535-5542
Published online on: 20 August 2018

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Article

Effects of let‑7c on the proliferation of ovarian carcinoma cells by targeted regulation of CDC25a gene expression

Wei Zhang, Qingru Zeng, Zhenying Ban, Jing Cao, Tianjiao Chu, Dongmei Lei, Chi Liu, Wentao Guo, Xianxu Zeng
Pages: 5543-5550
Published online on: 20 August 2018

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Article Open Access

Overexpression of circ‑0067934 is associated with increased cellular proliferation and the prognosis of non‑small cell lung cancer

Qinguang Zou, Tiejun Wang, Bai Li, Guanghu Li, Lixin Zhang, Bao Wang, Shaolin Sun
Pages: 5551-5556
Published online on: 23 August 2018

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Article Open Access

Puerarin 6''‑O‑xyloside possesses significant antitumor activities on colon cancer through inducing apoptosis

Xiao‑Lan Zhang, Bin‑Bin Wang, Jian‑Shu Mo
Pages: 5557-5564
Published online on: 24 August 2018

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Article Open Access

Gastric cancer with breast metastasis: Clinical features and prognostic factors

Yue Ma, Wenwen Liu, Junjian Li, Yingchun Xu, Hongxia Wang
Pages: 5565-5574
Published online on: 03 September 2018

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Article Open Access

Effects and mechanism of STAT3 silencing on the growth and apoptosis of colorectal cancer cells

Jing Li, You‑Yu Liu, Xue‑Feng Yang, Dao‑Fu Shen, Hong‑Zhi Sun, Ke‑Qiang Huang, Hua‑Chuan Zheng
Pages: 5575-5582
Published online on: 29 August 2018

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Article Open Access

Aberrant cystatin‑C expression in blood from patients with breast cancer is a suitable marker for monitoring tumor burden

Woo Sun Kwon, Tae Soo Kim, Chung Hyun Nahm, Yeonsook Moon, Jin Ju Kim
Pages: 5583-5590
Published online on: 03 September 2018

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Article Open Access

Elevated expression of POLD1 is associated with poor prognosis in breast cancer

Qinghong Qin, Qixing Tan, Jinyuan Li, Weiping Yang, Bin Lian, Qinguo Mo, Changyuan Wei
Pages: 5591-5598
Published online on: 04 September 2018

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Article Open Access

Complete endoscopic radical resection of thyroid cancer via an oral vestibule approach

Cong Bian, Hui Liu, Xi‑Yu Yao, Shu‑Ping Wu, Yu Wu, Chang Liu, Tian‑Shun Huang
Pages: 5599-5606
Published online on: 29 August 2018

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Article Open Access

Apatinib suppresses cell growth and metastasis and promotes antitumor activity of temozolomide in glioma

Chao Wang, Man Jiang, Helei Hou, Qiang Lin, Zhiyong Yan, Xiaochun Zhang
Pages: 5607-5614
Published online on: 23 August 2018

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Article Open Access

Analysis of correlation between HP infection and activation of PI3K/Akt pathway in mucosal tissues of gastric cancer and precancerous lesions

Yi Xie, Li Liu
Pages: 5615-5620
Published online on: 20 August 2018

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Article Open Access

Poly(ADP‑ribose) polymerase‑3 overexpression is associated with poor prognosis in patients with breast cancer following chemotherapy

Zhiguo Song, Yong Wang, Qinghuan Xia, Zhaojin Yu, Lin Zhao, Huizhe Wu, Mingli Sun, Zhangguo Chai, Ping Hou, Xiaoqiang Geng, Wensi Liu, Minjie Wei
Pages: 5621-5630
Published online on: 05 September 2018

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Article Open Access

Interaction of polymorphisms in xeroderma pigmentosum group C with cigarette smoking and pancreatic cancer risk

Xiao‑Hui Liang, Dong Yan, Jia‑Xing Zhao, Wei Ding, Xin‑Jian Xu, Xi‑Yan Wang
Pages: 5631-5638
Published online on: 23 August 2018

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Article Open Access

The LINC01186 suppresses cell proliferation and invasion ability in papillary thyroid carcinoma

Nanpeng Wang, Haisong Duan, Chen Zhang, Yan Zhou, Rongjun Gao
Pages: 5639-5644
Published online on: 22 August 2018

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Article Open Access

Inhibition of Ep3 attenuates migration and promotes apoptosis of non‑small cell lung cancer cells via suppression of TGF‑β/Smad signaling

Lei Li, Yanping Lv, Dengfeng Yan
Pages: 5645-5654
Published online on: 04 September 2018

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Article Open Access

Association of CD117 and HLA‑DR expression with shorter overall survival and/or progression‑free survival in patients with multiple myeloma treated with bortezomib and thalidomide combination treatment without transplantation

Huan Wang, Xin Zhou, Jian‑Wei Zhu, Jian‑Nan Ye, Hong‑Feng Guo, Chao Sun
Pages: 5655-5666
Published online on: 24 August 2018

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Article Open Access

Correlation of nm 23 expression with pharyngeal cancer and patient prognoses Retraction in /10.3892/ol.2025.15061

Wenzhong Wei, Xin Wei, Xiao Liang
Pages: 5667-5672
Published online on: 31 August 2018

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Article Open Access

Tumor suppression by Tegafur combined with Barbadian in S‑180 tumor‑bearing mice

Enning Zhang, Aiqin Fu, Weijun Chen, Xiaojie Wang
Pages: 5673-5678
Published online on: 30 August 2018

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Article Open Access

microRNA‑214 suppresses the growth of cervical cancer cells by targeting EZH2

Yanling Yang, Yang Liu, Guilin Li, Lei Li, Peng Geng, Hongjuan Song
Pages: 5679-5686
Published online on: 24 August 2018

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Article Open Access

Antitumor effect of ginsenoside Rg3 on gallbladder cancer by inducing endoplasmic reticulum stress‑mediated apoptosis in vitro and in vivo

Keren Wu, Jie Huang, Ning Li, Tao Xu, Wenyu Cai, Zhipeng Ye
Pages: 5687-5696
Published online on: 20 August 2018

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Article Open Access

Identification of ceRNA network based on a RNA‑seq shows prognostic lncRNA biomarkers in human lung adenocarcinoma

Xing Li, Bing Li, Pixin Ran, Lanying Wang
Pages: 5697-5708
Published online on: 21 August 2018

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Article Open Access

Hepatitis B virus X protein promotes epithelial‑mesenchymal transition and metastasis in hepatocellular carcinoma cell line HCCLM3 by targeting HMGA2

Yong Zha, Qian Yao, Jin‑Sheng Liu, Yuan‑Yuan Wang, Wei‑Ming Sun
Pages: 5709-5714
Published online on: 23 August 2018

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Article Open Access

CDH13 promoter methylation regulates cisplatin resistance of non-small cell lung cancer cells

Yan Wang, Lei Zhang, Jiasheng Yang, Bin Li, Jun Wang
Pages: 5715-5722
Published online on: 20 August 2018

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Article Open Access

Genetic expression profile‑based screening of genes and pathways associated with papillary thyroid carcinoma

Shubin Li, Yihang Yin, Hong Yu
Pages: 5723-5732
Published online on: 21 August 2018

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Article Open Access

Effects of TACE combined with precise RT on p53 gene expression and prognosis of HCC patients

Yupeng Liu, Jingchen Yan, Feng Wang
Pages: 5733-5738
Published online on: 30 August 2018

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Article Open Access

Effects of PLK1 on proliferation, invasion and metastasis of gastric cancer cells through epithelial-mesenchymal transition

Rui Song, Ge Hou, Jun Yang, Jinjin Yuan, Cheng Wang, Ting Chai, Zongwen Liu
Pages: 5739-5744
Published online on: 05 September 2018

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Article Open Access

PAR4 overexpression promotes colorectal cancer cell proliferation and migration

Hongshan Zhang, Ping Jiang, Chuanrao Zhang, Siman Lee, Wei Wang, Hao Zou
Pages: 5745-5752
Published online on: 05 September 2018

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Article Open Access

Combined expression of protein disulfide isomerase and endoplasmic reticulum oxidoreductin 1‑α is a poor prognostic marker for non‑small cell lung cancer

Kyoung Min Kim, Ae Ri An, Ho Sung Park, Kyu Yun Jang, Woo Sung Moon, Myoung Jae Kang, Yong Chul Lee, Ja Hong Ku, Myoung Ja Chung
Pages: 5753-5760
Published online on: 21 August 2018

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Article Open Access

Expression of PD‑L1 and SOX2 during rectal tumourigenesis: Potential mechanisms for immune escape and tumour cell invasion

Tim J. Miller, Melanie J. Mccoy, Christine Hemmings, Barry Iacopetta, Cameron F. Platell
Pages: 5761-5768
Published online on: 21 August 2018

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Article Open Access

Expression and significance of miR‑24 and miR‑101 in patients with advanced gastric cancer

Xuetao Dong, Yandi Liu
Pages: 5769-5774
Published online on: 17 August 2018

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Article Open Access

A prospective study to examine the accuracies and efficacies of prediction systems for response to neoadjuvant chemotherapy for muscle invasive bladder cancer

Yoichiro Kato, Hitoshi Zembutsu, Ryo Takata, Tomohiko Matsuura, Renpei Kato, Mitsugu Kanehira, Kazuhiro Iwasaki, Noriyuki Yamada, Toyomasa Katagiri, Tamotsu Sugai, Tomoaki Fujioka, Yusuke Nakamura, Wataru Obara
Pages: 5775-5784
Published online on: 20 August 2018

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Article Open Access

miR‑339‑5p inhibits lung adenocarcinoma invasion and migration by directly targeting BCL6

Peng Li, Huaqing Liu, Yanmeng Li, Yan Wang, Lin Zhao, Hui Wang
Pages: 5785-5790
Published online on: 31 August 2018

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Article Open Access

Trends of incidence and survival in patients with gastrointestinal mucinous adenocarcinoma

Zhen Zong, Yonghui Luo, Houqun Ying, Anan Wang, Hui Li, Chenghao Yi
Pages: 5791-5798
Published online on: 04 September 2018

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Article Open Access

DNMTs inhibitor SGI‑1027 induces apoptosis in Huh7 human hepatocellular carcinoma cells

Ning Sun, Jialin Zhang, Chengshuo Zhang, Bochao Zhao, Ao Jiao
Pages: 5799-5806
Published online on: 04 September 2018

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Article Open Access

A study of the application of fiberoptic bronchoscopy combined with liquid‑based cytology test in the early diagnosis of lung cancer

Songyan Han, Weihua Yang, Hongwei Li
Pages: 5807-5812
Published online on: 30 August 2018

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Article Open Access

Intra‑tumoral treatment with oxygen‑ozone in glioblastoma: A systematic literature search and results of a case series

Richard Megele, Markus J. Riemenschneider, Frank Dodoo‑Schittko, Matthias Feyrer, Andrea Kleindienst
Pages: 5813-5822
Published online on: 05 September 2018

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Article Open Access

Promoter methylation of Wrap53α, an antisense transcript of p53, is associated with the poor prognosis of patients with non‑small cell lung cancer

Dong Sun Kim, Won Kee Lee, Jae Yong Park
Pages: 5823-5828
Published online on: 05 September 2018

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Article Open Access

Downregulated SIRT6 and upregulated NMNAT2 are associated with the presence, depth and stage of colorectal cancer

Jia Qi, Chunhui Cui, Quanwen Deng, Lifeng Wang, Rihong Chen, Duanyang Zhai, Lang Xie, Jinlong Yu
Pages: 5829-5837
Published online on: 05 September 2018

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Article Open Access

Leptin and its receptor in glucose metabolism of T‑cell lymphoma

Tian‑Jie Han, Hong‑Zhi Xu, Jun‑Shan Li, Ling‑Yun Geng, Xin‑Yu Li, Xiang‑Xiang Zhou, Xin Wang
Pages: 5838-5846
Published online on: 23 August 2018

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Article Open Access

Identification of eight key miRNAs associated with renal cell carcinoma: A meta‑analysis

Guanghui Ying, Ruilan Wu, Min Xia, Xiapei Fei, Qi En He, Chenqin Zha, Fuquan Wu
Pages: 5847-5855
Published online on: 03 September 2018

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Article Open Access

Expression of circ_001569 is upregulated in osteosarcoma and promotes cell proliferation and cisplatin resistance by activating the Wnt/β‑catenin signaling pathway

Hongfei Zhang, Jiapeng Yan, Xujian Lang, Yuesheng Zhuang
Pages: 5856-5862
Published online on: 06 September 2018

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Case Report Open Access

Gastric cancer initially presenting as bone metastasis: Two case reports and a literature review

Daisuke Gomi, Toshirou Fukushima, Takashi Kobayashi, Nodoka Sekiguchi, Akiyuki Sakamoto, Keiko Mamiya, Tomonobu Koizumi
Pages: 5863-5867
Published online on: 04 September 2018

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Article Open Access

ATP‑binding cassette transporter A7 accelerates epithelial‑to‑mesenchymal transition in ovarian cancer cells by upregulating the transforming growth factor‑β signaling pathway Retraction in /10.3892/ol.2024.14483

Xia Liu, Qing Li, Jing Zhou, Su Zhang
Pages: 5868-5874
Published online on: 24 August 2018

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Article Open Access

miR‑124 regulates STAT3‑mediated cell proliferation, migration and apoptosis in bladder cancer

Shengxing Wang, Gang Wu, Yinan Han, Peng Song, Jinhuo Chen, Yaoxi Wu, Jie Yang, Peiyu Liang
Pages: 5875-5881
Published online on: 21 August 2018

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Article Open Access

Hepatectomy plus adjuvant transcatheter arterial chemoembolization improves the survival rate of patients with multicentric occurrence of hepatocellular carcinoma

Da Xu, Xiaofeng Liu, Lijun Wang, Baocai Xing
Pages: 5882-5890
Published online on: 20 August 2018

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Article Open Access

A 20(S)‑protopanaxadiol derivative PPD12 reverses ABCB1‑mediated multidrug resistance with oral bioavailability and low toxicity

Shunfeng Wei, Wantao Chen, Lihong Hu, Jinsong Pan, Xu Wang
Pages: 5891-5899
Published online on: 21 August 2018

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Article Open Access

Never‑in‑mitosis A‑related kinase 8, a novel target of von‑Hippel‑Lindau tumor suppressor protein, promotes gastric cancer cell proliferation

Xiao‑Fei Ding, Jie Chen, Jun Zhou, Guang Chen, Ying‑Liang Wu
Pages: 5900-5906
Published online on: 20 August 2018

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Article Open Access

A‑kinase anchoring protein 12 is downregulated in human hepatocellular carcinoma and its deficiency in mice aggravates thioacetamide‑induced liver injury

Hye Shin Lee, Jinhyeok Choi, Taekwon Son, Eun Ji Lee, Jeong‑Gyun Kim, Soo Hyung Ryu, Danbi Lee, Myoung Kuk Jang, Eunsil Yu, Young‑Hwa Chung, Irwin H. Gelman, Kyu‑Won Kim
Pages: 5907-5915
Published online on: 04 September 2018

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Article Open Access

SERINC2‑knockdown inhibits proliferation, migration and invasion in lung adenocarcinoma

Yuan Zeng, Dakai Xiao, Huiming He, Jiaxi He, Hui Pan, Wei Yang, Yaoqi Chen, Jianxing He
Pages: 5916-5922
Published online on: 05 September 2018

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Article Open Access

Doxorubicin resistance induces IL6 activation in the colon cancer cell line LS180

Xiao‑Yun Li, Xiao‑Feng Liao, Hong‑Bo Wang, Jian Zhang
Pages: 5923-5929
Published online on: 23 August 2018

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Article Open Access

Expression of TRPM8 in human reactive lymphoid tissues and mature B‑cell neoplasms

Akinori Hirai, Naing Ye Aung, Rintaro Ohe, Akiko Nishida, Tomoya Kato, Hongxue Meng, Kenichi Ishizawa, Junichi Fujii, Mitsunori Yamakawa
Pages: 5930-5938
Published online on: 03 September 2018

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Article Open Access

Feasibility of 2D‑conformal radiotherapy for pancreatic carcinoma

Milly Buwenge, Savino Cilla, Silvia Cammelli, Gabriella Macchia, Alessandra Arcelli, Eleonora Farina, Rezarta Frakulli, Valeria Panni, Tigeneh Wondemagegnhu, A. F. M. Kamal Uddin, Mostafa A. Sumon, Francesco Deodato, Alessio G. Morganti
Pages: 5939-5945
Published online on: 04 September 2018

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Article Open Access

MicroRNA‑206 suppresses proliferation and predicts poor prognosis of HR‑HPV-positive cervical cancer cells by targeting G6PD

Jinpeng Cui, Yinghua Pan, Jianhua Wang, Yan Liu, Hongyan Wang, Hongyan Li
Pages: 5946-5952
Published online on: 20 August 2018

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Article Open Access

Pyk2 promotes tumor progression in renal cell carcinoma

Tangliang Zhao, Yi Bao, Xin Lu, Yi He, Xinxin Gan, Jianchao Wang, Bing Liu, Linhui Wang
Pages: 5953-5959
Published online on: 06 September 2018

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Article Open Access

Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China

Ying Liu, Lulu Xu, Hongliang Wu, Na Zhao, Yanchun Tang, Xiaoping Li, Ying Liang
Pages: 5960-5968
Published online on: 05 September 2018

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Article Open Access

Iodine‑125 interstitial brachytherapy reduces tumor growth via Warburg effect inhibition in non‑small cell lung cancer A549 xenografts

Jun Zhang, Yangjun Zhu, Mengjie Dong, Jun Yang, Wanwen Weng, Lisong Teng
Pages: 5969-5977
Published online on: 21 August 2018

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Article Open Access

Role of nutritional support for postoperative recovery of respiratory function in patients with primary lung cancer

Jinhong Yang, Qianqian Zhang, Xiaoli Wang
Pages: 5978-5982
Published online on: 22 August 2018

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Article Open Access

Hepatocyte growth factor‑induced mesenchymal‑epithelial transition factor activation leads to insulin‑like growth factor 1 receptor inhibitor unresponsiveness in gastric cancer cells

Rujiao Liu, Wenbo Tang, Xiaotian Han, Ruixuan Geng, Chenchen Wang, Zhe Zhang
Pages: 5983-5991
Published online on: 06 September 2018

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Article Open Access

Crizotinib induces apoptosis of lung cancer cells through JAK-STAT pathway

Hongmin Lu, Shibo Wu, Huafei Chen, Ying Huang, Guoqin Qiu, Lingxiang Liu, Yong Li
Pages: 5992-5996
Published online on: 04 September 2018

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Article

Expression and significance of quantum dots in RAW 264.7 macrophages

Chong Li, Panpan Zhang, Yanming Hao, Dawei He, Yixin Shen, Rongzhu Lu
Pages: 5997-6002
Published online on: 24 August 2018

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Article

Somatic mutation profiling of liver and biliary cancer by targeted next generation sequencing

Bo‑Lun Zhang, Xu Ji, Ling‑Xiang Yu, Yuan Gao, Chao‑Hui Xiao, Jia Liu, De‑Xi Zhao, Yi Le, Guang‑Hao Diao, Jia‑Yi Sun, Gao‑Hua Li, Guang‑Lin Lei, Peng Yu, Rui‑Lan Wang, Jian‑Zhong Wu, Peng‑Hui Yang, Jin Yan, Jing‑Yu Li, Jia‑Jia Xu, Shao‑Geng Zhang, Hu Tian
Pages: 6003-6012
Published online on: 29 August 2018

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Article

Prognostic impact of soluble intercellular adhesion molecule‑1 in hepatocellular carcinoma

Tatsuo Shimura, Masahiko Shibata, Kenji Gonda, Yasuhide Kofunato, Teruhide Ishigame, Ryo Okada, Naoya Sato, Takashi Kimura, Akira Kenjo, Shigeru Marubashi
Pages: 6013-6018
Published online on: 24 August 2018

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Article

β‑elemene induced anticancer effect in bladder cancer through upregulation of PTEN and suppression of AKT phosphorylation

Bo Cai, Limin Ma, Shaojun Nong, You Wu, Xin Guo, Jinxian Pu
Pages: 6019-6025
Published online on: 05 September 2018

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Article

Differential expression profiles of microRNAs in highly and weakly invasive/metastatic pancreatic cancer cells

Xiaodong Tan, Lei Zhou, Huaitao Wang, Yifan Yang, Yang Sun, Zhaoping Wang, Xiaobo Zhang, Feng Gao, Hansi Li
Pages: 6026-6038
Published online on: 23 August 2018

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Article

Antitumorigenic effect of damnacanthal on melanoma cell viability through p53 and NF‑κB/caspase‑3 signaling pathways

Xin Zhang, Ping Fang, Zigang Zhao, Xiangyu Ding, Fang Xie, Yilin Wang, Chengxin Li
Pages: 6039-6044
Published online on: 03 September 2018

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Article

MicroRNA‑133a downregulated EGFR expression in human non‑small cell lung cancer cells via AKT/ERK signaling

Nannan Guo, Yingnan Zhao, Wen Zhang, Shaojun Li, Shanshan Li, Jianqi Yu
Pages: 6045-6050
Published online on: 05 September 2018

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Article Open Access

Long noncoding RNA Z38 promotes cell proliferation and metastasis and inhibits cell apoptosis in human gastric cancer

Yang Wang, Chunhui Zheng, Teng Li, Rui Zhang, Jiaxin Zhang, Qingsi He, Zuocheng Sun, Xinsheng Wang
Pages: 6051-6058
Published online on: 21 August 2018

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Article

AQP9 promotes astrocytoma cell invasion and motility via the AKT pathway

Yao Lv, Qiang Huang, Weimin Dai, Yuanqing Jie, Guofeng Yu, Xiaofeng Fan, An Wu, Qian Miao
Pages: 6059-6064
Published online on: 23 August 2018

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Article

Serum vascular endothelial growth factor‑C levels predict lymph node metastasis and prognosis of patients with gallbladder cancer

Lei Jiang, Minchao Liu, Xinran Cai, Lijun Xie, Feifei She, Yanling Chen
Pages: 6065-6070
Published online on: 23 August 2018

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Article

Metformin reverses the resistance mechanism of lung adenocarcinoma cells that knocks down the Nrf2 gene

Jiacui Zhang, Keping Jiao, Jing Liu, Yu Xia
Pages: 6071-6080
Published online on: 03 September 2018

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Article

TM4SF1 inhibits apoptosis and promotes proliferation, migration and invasion in human gastric cancer cells

Yunhai Wei, Xiaoying Shen, Liqin Li, Guoliang Cao, Xuhua Cai, Yan Wang, Hua Shen
Pages: 6081-6088
Published online on: 06 September 2018

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Case Report

Genomic profiling of synchronous triple primary tumors of the lung, thyroid and kidney in a young female patient: A case report

Ling Peng, Zhu Zeng, Xiaodong Teng, Zhen Chen, Lili Lin, Hua Bao, Yang W. Shao, Yina Wang, Yongquan Dong, Qiong Zhao
Pages: 6089-6094
Published online on: 20 August 2018

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Article

Effects of NOTCH1 signaling inhibitor γ‑secretase inhibitor II on growth of cancer stem cells

Xiaodong Ding, Changqing Ding, Fei Wang, Wenshuai Deng, Mingming Yu, Qinghai Meng, Peng Sun
Pages: 6095-6099
Published online on: 03 September 2018

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Article

Downregulation of 5‑hydroxytryptamine receptor 3A expression exerts an anticancer activity against cell growth in colorectal carcinoma cells in vitro

Jian Tang, Zheng Wang, Jiahua Liu, Chao Zhou, Jinxian Chen
Pages: 6100-6108
Published online on: 23 August 2018

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Article

Long non‑coding RNA SUMO1P3 may promote cell proliferation, migration, and invasion of pancreatic cancer via EMT signaling pathway

Chuang Tian, Yong Jin, Songshan Shi
Pages: 6109-6115
Published online on: 03 September 2018

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Case Report

Bulky primary tibia mantle cell lymphoma achieved complete remission with CHOP and DHAP plus rituximab: A case report

Si Chen, Meng Ye
Pages: 6116-6120
Published online on: 29 August 2018

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Case Report

The novel three‑way variant t(6;17;15)(p21;q21;q22) in acute promyelocytic leukemia with an FLT3‑ITD mutation: A case report

Yong‑Lu Zhang, Mei Jiang, Shu‑Qing Luan, Shu‑Yuan Liu, Jin‑Hua Wan, La‑Gen Wan, Zhang‑Lin Zhang
Pages: 6121-6125
Published online on: 06 September 2018

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Article

A dosimetric study on radiation‑induced hypothyroidism following intensity‑modulated radiotherapy in patients with nasopharyngeal carcinoma

Yumei Xu, Zhiying Shao, Tianyou Tang, Guihong Liu, Yuanhu Yao, Jianshe Wang, Longzhen Zhang
Pages: 6126-6132
Published online on: 20 August 2018

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Article

Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells

Tao Tian, Jinpeng Sun, Jianxin Wang, Yanchun Liu, Haitao Liu
Pages: 6133-6139
Published online on: 21 August 2018

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Article

CHSY1 promoted proliferation and suppressed apoptosis in colorectal cancer through regulation of the NFκB and/or caspase‑3/7 signaling pathway

Lifeng Zeng, Jinrong Qian, Xiaojiang Luo, Aiqun Zhou, Zhiyong Zhang, Quangang Fang
Pages: 6140-6146
Published online on: 03 September 2018

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Article

The role of protein p16INK4a in non‑oropharyngeal head and neck squamous cell carcinoma in Southern China

Hang Yang, Ye Cao, Zhi‑Ming Li, Ya‑Jun Li, Wen‑Qi Jiang, Yan‑Xia Shi
Pages: 6147-6155
Published online on: 23 August 2018

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Article

Anti‑IL‑20 monoclonal antibody suppresses hepatocellular carcinoma progression

Wen‑Zhou Ding, Guo‑Yong Han, Hui‑Han Jin, Chuan‑Fei Zhan, Yuan Ji, Xin‑Li Huang
Pages: 6156-6162
Published online on: 05 September 2018

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Article

Potential function of CTLA‑4 in the tumourigenic capacity of melanoma stem cells

Bingyu Zhang, Jianzhong Dang, Diandian Ba, Cencen Wang, Juan Han, Fang Zheng
Pages: 6163-6170
Published online on: 23 August 2018

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Article

Serum thymidine kinase 1 is associated with Gleason score of patients with prostate carcinoma

Shujing Li, Jianping Zhou, Yu Wang, Keqin Zhang, Junjie Yang, Xinling Zhang, Chunmei Wang, Hongbo Ma, Ji Zhou, Ellen He, Sven Skog
Pages: 6171-6180
Published online on: 21 August 2018

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Article

Viability of glioblastoma stem cells is effectively reduced by diisothiocyanate‑derived mercapturic acids

Kamila Cwiklowska, Mike‑Andrew Westhoff, Simon Freisinger, Annika Dwucet, Marc‑Eric Halatsch, Uwe Knippschild, Klaus‑Michael Debatin, Reinhold Schirmbeck, Lukasz Winiarski, Jozef Oleksyszyn, Christian Rainer Wirtz, Timo Burster
Pages: 6181-6187
Published online on: 21 August 2018

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Article

EPA significantly improves anti‑EGFR targeted therapy by regulating miR‑378 expression in colorectal cancer

Wen‑Hui Weng, Wai‑Hung Leung, Yeu Jye Pang, Li‑Wei Kuo, Hsi‑Hsien Hsu
Pages: 6188-6194
Published online on: 05 September 2018

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Article

Kaempferol, a natural dietary flavonoid, suppresses 17β‑estradiol‑induced survivin expression and causes apoptotic cell death in endometrial cancer

Agapiti Hipoliti Chuwa, Kenbun Sone, Katsutoshi Oda, Michihiro Tanikawa, Asako Kukita, Machiko Kojima, Shinya Oki, Tomohiko Fukuda, Makoto Takeuchi, Aki Miyasaka, Tomoko Kashiyama, Yuji Ikeda, Kazunori Nagasaka, Mayuyo Mori‑Uchino, Yoko Matsumoto, Osamu Wada‑Hiraike, Hiroyuki Kuramoto, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii
Pages: 6195-6201
Published online on: 21 August 2018

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Article

Histone deacetylase inhibitors sensitize 5‑fluorouracil‑resistant MDA‑MB‑468 breast cancer cells to 5‑fluorouracil

Tetsuya Minegaki, Ai Suzuki, Misato Mori, Shiori Tsuji, Satoshi Yamamoto, Airi Watanabe, Tomoyo Tsuzuki, Takaki Tsunoda, Asuka Yamamoto, Masayuki Tsujimoto, Kohshi Nishiguchi
Pages: 6202-6208
Published online on: 04 September 2018

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Retraction Open Access

[Retracted] Analysis of YAP1 and TAZ expression by immunohistochemical staining in malignant mesothelioma and reactive mesothelial cells

Yusuke Takehara, Toshiko Yamochi, Tasuku Nagumo, Tomonari Cho, Fumihiko Urushibara, Kohei Ono, Tomonori Fujii, Naoko Okamoto, Yosuke Sasaki, Sakiko Tazawa, Mayumi Honma, Tomoko Norose, Eisuke Shiozawa, Genshu Tate, Masafumi Takimoto
Pages: 6209-6209
Published online on: 05 September 2018

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Review Open Access

Th17 response in patients with cervical cancer (Review)

Jayra Juliana Paiva Alves, Thales Allyrio Araújo de Medeiros Fernandes, Josélio Maria Galvão de Araújo, Ricardo Ney Oliveira Cobucci, Daniel Carlos Ferreira Lanza, Fabiana Lima Bezerra, Vânia Sousa Andrade, José Veríssimo Fernandes
Pages: 6215-6227
Published online on: 21 September 2018

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Review

Progress in the chemotherapeutic treatment of osteosarcoma (Review)

Ya Zhang, Jingqing Yang, Na Zhao, Cao Wang, Santosh Kamar, Yonghong Zhou, Zewei He, Jifei Yang, Bin Sun, Xiaoqian Shi, Lei Han, Zuozhang Yang
Pages: 6228-6237
Published online on: 12 September 2018

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Article Open Access

High concordance of TMPRSS‑ERG fusion between primary prostate cancer and its lymph node metastases

Franziska Brandi, Katharina Grupp, Claudia Hube‑Magg, Martina Kluth, Dagmar Lang, Sarah Minner, Christina Möller‑Koop, Markus Graefen, Hans Heinzer, Maria Christina Tsourlakis, Corinna Wittmer, Frank Jacobsen, Hartwig Huland, Stefan Steurer, Patrick Lebok, Andrea Hinsch, Waldemar Wilczak, Thorsten Schlomm, Ronald Simon
Pages: 6238-6244
Published online on: 07 September 2018

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Article Open Access

Long non‑coding RNA, CHRF, predicts poor prognosis of lung adenocarcinoma and promotes cell proliferation and migration

Xiaowei Xie, Wei Zhao, Jinglin Pang, Xiaomiao Xiong, Haiyan Wang, Lingyun Ma
Pages: 6245-6252
Published online on: 07 September 2018

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Article Open Access

MicroRNA‑195 as a diagnostic biomarker in human cancer detection: A meta‑analysis

Baoer Liu, Yuhan Liu, Xueying Luo, Yue Pan, Liping Yang, Feng Li, Rui Gao, Weicai Chen, Jinsong He
Pages: 6253-6260
Published online on: 24 September 2018

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Article Open Access

Filamin A inhibits tumor progression through regulating BRCA1 expression in human breast cancer

Yundi Guo, Ming Li, Guanghui Bai, Xiaoning Li, Zhongwen Sun, Jie Yang, Lu Wang, Jing Sun
Pages: 6261-6266
Published online on: 20 September 2018

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Article Open Access

Arsenic trioxide induces the apoptosis and decreases NF‑κB expression in lymphoma cell lines

Lu Zhong, Fei Xu, Fangyuan Chen
Pages: 6267-6274
Published online on: 07 September 2018

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Article Open Access

Synergistic antitumor effect of the combination of a dual cancer‑specific oncolytic adenovirus and cisplatin on lung cancer cells

Jing Jin, Yilong Zhu, Fei Sun, Zhifei Chen, Shuang Chen, Yiquan Li, Wenjie Li, Min Li, Chuanxin Cui, Yingli Cui, Xunzhi Yin, Shanzhi Li, Jin Zhao, Guo Yan, Xiao Li, Ningyi Jin
Pages: 6275-6282
Published online on: 20 September 2018

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Article Open Access

A gene mutation in RNA‑binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis

Lin‑Lin Yin, Xin‑Mian Wen, Ming Li, Yan‑Mei Xu, Xiao‑Feng Zhao, Jing Li, Xiu‑Wen Wang
Pages: 6283-6292
Published online on: 24 September 2018

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Article Open Access

MicroRNA‑661 expression is upregulated in pancreatic ductal adenocarcinoma and promotes cell proliferation

Feifei Lv, Kehong Zheng, Jinlong Yu, Zonghai Huang
Pages: 6293-6298
Published online on: 18 September 2018

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Article Open Access

Hesperidin exhibits in vitro and in vivo antitumor effects in human osteosarcoma MG‑63 cells and xenograft mice models via inhibition of cell migration and invasion, cell cycle arrest and induction of mitochondrial‑mediated apoptosis Retraction in /10.3892/ol.2023.13703

Guang‑Yu Du, Sheng‑Wei He, Lu Zhang, Chuan‑Xiu Sun, Li‑Dong Mi, Zue‑Gang Sun
Pages: 6299-6306
Published online on: 14 September 2018

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Article Open Access

High expression of GALNT7 promotes invasion and proliferation of glioma cells

Shi Hua, Hongyan Li, Yuguang Liu, Jian Zhang, Yanhao Cheng, Chao Dai
Pages: 6307-6314
Published online on: 25 September 2018

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Article Open Access

Regulating glioma stem cells by hypoxia through the Notch1 and Oct3/4 signaling pathway

Fei Zeng, Hong Chen, Zhaohui Zhang, Tao Yao, Guan Wang, Qingxing Zeng, Shenhan Duan, Yanqiang Zhan
Pages: 6315-6322
Published online on: 17 September 2018

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Article Open Access

Synergistic inhibitory effects of cetuximab and curcumin on human cisplatin‑resistant oral cancer CAR cells through intrinsic apoptotic process

Chin‑Fu Chen, Chi‑Cheng Lu, Jo‑Hua Chiang, Hong‑Yi Chiu, Jai‑Sing Yang, Chao‑Ying Lee, Tzong‑Der Way, Hao‑Jen Huang
Pages: 6323-6330
Published online on: 07 September 2018

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Article Open Access

Fractional uptake of circulating tumor cells into liver‑lung compartments during curative resection of periampullary cancer

Caroline Vilhav, Cecilia Engström, Peter Naredi, Ann Novotny, Johan Bourghardt‑Fagman, Britt‑Marie Iresjö, Annika G. Asting, Kent Lundholm
Pages: 6331-6338
Published online on: 12 September 2018

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Article Open Access

Imbalanced expression pattern of steroid receptor coactivator‑1 and ‑3 in liver cancer compared with normal liver: An immunohistochemical study with tissue microarray

Shan Li, Huiyan Zhang, Yanlan Yu, Mengying Liu, Deyu Guo, Xuqing Zhang, Jiqiang Zhang
Pages: 6339-6348
Published online on: 17 September 2018

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Application of novel targeted molecular imaging probes in the early diagnosis of upper urinary tract epithelial carcinoma

Guodong Liao, Lijiang Wang, Weiwen Yu
Pages: 6349-6354
Published online on: 11 September 2018

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Article Open Access

miR-145-5p inhibits the proliferation and migration of bladder cancer cells by targeting TAGLN2

Haijian Zhang, Meijuan Jiang, Qingjun Liu, Zhixing Han, Yuqian Zhao, Shiqi Ji
Pages: 6355-6360
Published online on: 12 September 2018

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Article

The SOX2OT/miR‑194‑5p axis regulates cell proliferation and mobility of gastric cancer through suppressing epithelial‑mesenchymal transition

Ruqiong Wei, Can Ding, Raquel Alarcòn Rodrìguez, Marìa del Mar Requena Mullor
Pages: 6361-6368
Published online on: 12 September 2018

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Article Open Access

MicroRNA‑140‑5p suppresses cell proliferation and invasion in gastric cancer by targeting WNT1 in the WNT/β‑catenin signaling pathway

Yinlian Cha, Ying He, Kaobin Ouyang, Hailin Xiong, Jun Li, Xia Yuan
Pages: 6369-6376
Published online on: 21 September 2018

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Article Open Access

Knockdown of LETM1 inhibits proliferation and metastasis of human renal cell carcinoma cells

Jie Xu, Bisheng Huang, Saiyang Li, Xiaolu Zhang, Tiancheng Xie, Yunfei Xu
Pages: 6377-6382
Published online on: 18 September 2018

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Article Open Access

Outcomes following liver resection for multinodular Barcelona Clinic Liver Cancer‑B hepatocellular carcinoma

Satoshi Matsukuma, Kazuhiko Sakamoto, Yoshihiro Tokuhisa, Yukio Tokumitsu, Hiroto Matsui, Shinsuke Kanekiyo, Shinobu Tomochika, Michihisa Iida, Nobuaki Suzuki, Shigeru Takeda, Tomio Ueno, Hiroshi Wada, Shogo Kobayashi, Issei Saeki, Hidetoshi Eguchi, Masato Sakon, Isao Sakaida, Hiroaki Nagano
Pages: 6383-6392
Published online on: 07 September 2018

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Article Open Access

MicroRNA‑143 regulates cell migration and invasion by targeting GOLM1 in cervical cancer

Meiying Zhou, Xiaohong Chen, Jian Wu, Xiaoyan He, Rui Ren
Pages: 6393-6400
Published online on: 17 September 2018

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Article Open Access

Identification of novel long non‑coding RNA in diffuse intrinsic pontine gliomas by expression profile analysis

Yuehui Liu, Haiping Liu, Dongwei Zhang
Pages: 6401-6406
Published online on: 19 September 2018

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Screening of differentially methylated genes in breast cancer and risk model construction based on TCGA database

Liang Feng, Feng Jin
Pages: 6407-6416
Published online on: 19 September 2018

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Article Open Access

Aclidinium inhibits proliferation and metastasis of ovarian cancer SKOV3 cells via downregulating PI3K/AKT/mTOR signaling pathway

Juan Qiao, Wei-Jing Wang, Yuan Zhang
Pages: 6417-6422
Published online on: 19 September 2018

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Article Open Access

Cytoplasmic CD133 expression correlates with histologic differentiation and is a significant prognostic factor in extrahepatic bile duct cancer and gallbladder cancer

Tatsuzo Mizukami, Hirofumi Kamachi, Tomoko Mitsuhashi, Takahiro Einama, Yutaka Hatanaka, Toshiya Kamiyama, Akinobu Taketomi
Pages: 6423-6430
Published online on: 25 September 2018

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Case Report Open Access

A comprehensive gene mutation analysis of liquid biopsy samples from patients with metastatic colorectal cancer to the ovary: A case report

Naoyuki Iwahashi, Kazuko Sakai, Tomoko Noguchi, Tamaki Yahata, Saori Toujima, Kazuto Nishio, Kazuhiko Ino
Pages: 6431-6436
Published online on: 20 September 2018

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Article Open Access

Aberrant expression of glycogen synthase kinase‑3β in human breast and head and neck cancer

Andrey V. Ugolkov, Maria Matsangou, Timothy J. Taxter, Thomas V. O'Halloran, Vincent L. Cryns, Francis J. Giles, Andrew P. Mazar
Pages: 6437-6444
Published online on: 21 September 2018

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Article Open Access

Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF‑1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase‑3 signaling pathway in small cell lung cancer

Wenli Jiang, Linghong Meng, Guangming Xu, Cuiting Lv, Hongliang Wang, He Tian, Ruohua Chen, Binghua Jiao, Bingui Wang, Caiguo Huang
Pages: 6445-6457
Published online on: 24 September 2018

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Article Open Access

Lectin histochemical analysis of uterine natural killer cells in normal, hydatidiform molar and invasive molar pregnancy

Ting Zhong, Xingxing Xie, Teng Zong, Xiaochun Yu, Yan Ling, Haibin Kuang
Pages: 6458-6464
Published online on: 20 September 2018

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Article Open Access

EMT induced by loss of LKB1 promotes migration and invasion of liver cancer cells through ZEB1‑induced YAP signaling

Bijun Qiu, Wei Wei, Jianwen Zhu, Guangshun Fu, Dahai Lu
Pages: 6465-6471
Published online on: 18 September 2018

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Article Open Access

miR‑491‑5p inhibits osteosarcoma cell proliferation by targeting PKM2

Ting Chen, Yuyang Li, Wenliang Cao, Yadong Liu
Pages: 6472-6478
Published online on: 18 September 2018

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Article Open Access

MicroRNA 141 represses nasopharyngeal carcinoma growth through inhibiting BMI1

Fei Liu, Wenjuan Wang, Shuo Li, Qiong Yang, Jing Hu, Nan Zeng, Chunsheng Gao
Pages: 6479-6487
Published online on: 18 September 2018

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Article Open Access

Barrier‑to‑autointegration factor 1: A novel biomarker for gastric cancer

Junjun Li, Bingbing Hu, Lei Fang, Yang Gao, Shuai Shi, Haoyu He, Xiaomei Liu, Caijun Yuan
Pages: 6488-6494
Published online on: 11 September 2018

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Article Open Access

Upregulation of circRNA_0000285 serves as a prognostic biomarker for nasopharyngeal carcinoma and is involved in radiosensitivity

Mingxia Shuai, Jangwei Hong, Donghai Huang, Xin Zhang, Yongquan Tian
Pages: 6495-6501
Published online on: 20 September 2018

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Article Open Access

Osteosarcoma in patients below 25 years of age: An observational study of incidence, metastasis, treatment and outcomes

Zhigang Nie, Hao Peng
Pages: 6502-6514
Published online on: 18 September 2018

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Article Open Access

Ganoderic acid A exerts antitumor activity against MDA‑MB‑231 human breast cancer cells by inhibiting the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway

Yuguang Yang, Hongfeng Zhou, Wenming Liu, Jin Wu, Xiaolong Yue, Jincai Wang, Lina Quan, Hang Liu, Li Guo, Zhipeng Wang, Xin Lian, Qingyuan Zhang
Pages: 6515-6521
Published online on: 21 September 2018

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Article Open Access

Synthesis and pharmacological evaluation of novel epidermal growth factor receptor inhibitors against prostate tumor cells

Yi Zhi, Xiaojun Wu, Wenhao Shen, Yongquan Wang, Xiaozhou Zhou, Peng He, Jinhong Pan, Zhiwen Chen, Weibing Li, Zhansong Zhou
Pages: 6522-6530
Published online on: 14 September 2018

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Article Open Access

Low expression of miR‑199 in hepatocellular carcinoma contributes to tumor cell hyper‑proliferation by negatively suppressing XBP1

Zheng Lou, Yong‑Qiang Gong, Xing Zhou, Guo‑Huang Hu
Pages: 6531-6539
Published online on: 21 September 2018

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Article Open Access

Lipid rafts regulate the lamellipodia formation of melanoma A375 cells via actin cytoskeleton‑mediated recruitment of β1 and β3 integrin

Jiajia Bi, Ruifei Wang, Xianlu Zeng
Pages: 6540-6546
Published online on: 20 September 2018

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Article Open Access

Effect of anesthetic methods on postoperative CD3+, CD4+ and CD4+CD25+ in patients with lung cancer undergoing radical operation

Shuang Fu, Pi-Sheng Qu, Shu-Nv Cai
Pages: 6547-6551
Published online on: 07 September 2018

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HDAC inhibitor apicidin suppresses murine oral squamous cell carcinoma cell growth in vitro and in vivo via inhibiting HDAC8 expression

Mee‑Young Ahn
Pages: 6552-6560
Published online on: 20 September 2018

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Short‑term curative effect and safety of propranolol combined with laser in the treatment of infantile hemangiomas

Xinjun Sun, Xiang Liu, Nan Lu, Shulan Yao, Xiguang Xu, Lili Niu
Pages: 6561-6565
Published online on: 24 September 2018

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miR-34a targets BCL-2 to suppress the migration and invasion of sinonasal squamous cell carcinoma

Yigang Zhao, Xianzhi Wang
Pages: 6566-6572
Published online on: 11 September 2018

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Therapeutic effects of lenvatinib in combination with rAd‑p53 for the treatment of non‑small cell lung cancer

Renzhi Yu, Minghuan Wang, Xiuli Zhu, Zhe Sun, Aiying Jiang, Huixin Yao
Pages: 6573-6581
Published online on: 11 September 2018

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Invasive bronchial fibroblasts derived from asthmatic patients activate lung cancer A549 cells in vitro

Damian Ryszawy, Filip Rolski, Karolina Ryczek, Jessica Catapano, Tomasz Wróbel, Marta Michalik, Jarosław Czyż
Pages: 6582-6588
Published online on: 19 September 2018

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Article Open Access

Retrospective study of regorafenib and trifluridine/tipiracil efficacy as a third‑line or later chemotherapy regimen for refractory metastatic colorectal cancer

Akira Tanaka, Sotaro Sadahiro, Toshiyuki Suzuki, Kazutake Okada, Gota Saito, Hiroshi Miyakita
Pages: 6589-6597
Published online on: 07 September 2018

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Article Open Access

Relationship between CT signs and the expression of miR‑146a in colon cancer

Zijian Liu, Yuzhu Li, Quanxiang Luo
Pages: 6598-6602
Published online on: 07 September 2018

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Article Open Access

Ethnicity based variation in expression of E‑cadherin in patients with squamous cell carcinoma of the oral tongue

Nicola Sgaramella, Torben Wilms, Linda Boldrup, Lotta Loljung, Xiaolian Gu, Philip J. Coates, Petra Hassellöf, Luigi Califano, Lorenzo Lo Muzio, Robin Fåhraeus, Lena Norberg Spaak, Renato Franco, Gianpaolo Tartaro, Giuseppe Colella, Mario Santagata, Giovanni Dell'Aversana Orabona, Fabrizio Chirico, Karin Danielsson, Giuseppe Troiano, Fatima Ardito, Karin Nylander
Pages: 6603-6607
Published online on: 18 September 2018

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Low dose dinaciclib enhances doxorubicin‑induced senescence in myeloma RPMI8226 cells by transformation of the p21 and p16 pathways

Hailong Tang, Li Xu, Xue Liang, Guangxun Gao
Pages: 6608-6614
Published online on: 20 September 2018

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Butein induces apoptotic cell death of human cervical cancer cells

Pei‑Yu Yang, Dan‑Ning Hu, Ying‑Hsien Kao, I‑Ching Lin, Fu‑Shing Liu
Pages: 6615-6623
Published online on: 07 September 2018

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Case Report Open Access

Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review

Xiaorui Fu, Yufeng Shang, Lei Zhang, Ling Li, Xin Li, Xinhua Wang, Zhenchang Sun, Mingzhi Zhang
Pages: 6624-6632
Published online on: 18 September 2018

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Association of PTEN expression with liver function and inflammatory changes in patients with liver cancer after chemotherapy

Jixiang Zhou, Xiaoli Li
Pages: 6633-6637
Published online on: 19 September 2018

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Expression of miRNA‑206 and miRNA‑145 in breast cancer and correlation with prognosis

Yan Quan, Xianxi Huang, Xiaoxiang Quan
Pages: 6638-6642
Published online on: 17 September 2018

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Serum levels of candidate microRNA diagnostic markers differ among the stages of non‑small‑cell lung cancer

Toshiko Aiso, Kouki Ohtsuka, Makiko Ueda, Shin Karita, Takuma Yokoyama, Saori Takata, Naoko Matsuki, Haruhiko Kondo, Hajime Takizawa, Annabelle A. Okada, Takashi Watanabe, Hiroaki Ohnishi
Pages: 6643-6651
Published online on: 20 September 2018

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A potential common role of the Jumonji C domain‑containing 1A histone demethylase and chromatin remodeler ATRX in promoting colon cancer

Xiaomeng Li, Sangphil Oh, Hoogeun Song, Sook Shin, Bin Zhang, Willard M. Freeman, Ralf Janknecht
Pages: 6652-6662
Published online on: 24 September 2018

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Identification of the key genes and pathways in prostate cancer

Shutong Fan, Zumu Liang, Zhiqin Gao, Zhiwei Pan, Shaojie Han, Xiaoying Liu, Chunling Zhao, Weiwei Yang, Zhifang Pan, Weiguo Feng
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Published online on: 24 September 2018

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Mapping of new skin tumor susceptibility loci by a phenotype‑driven congenic approach

Kyoko Fujiwara, Yoshinori Inagaki, Masayoshi Soma, Toshinori Ozaki, Hiroki Nagase
Pages: 6670-6676
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Evaluation of positive ductal margins of biliary tract cancer in intraoperative histological examination

Junji Ueda, Hiroshi Yoshida, Yasuhiro Mamada, Nobuhiko Taniai, Masato Yoshioka, Atsushi Hirakata, Youichi Kawano, Yoshiaki Mizuguchi, Tetsuya Shimizu, Tomohiro Kanda, Hideyuki Takata, Ryota Kondo, Eiji Uchida
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Published online on: 21 September 2018

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Nitric oxide functions in stromal cell‑derived factor‑1‑induced cytoskeleton changes and the migration of Jurkat cells

Jixian Luo, Dan Wei, Dingyun Li, Lan Wang
Pages: 6685-6690
Published online on: 11 September 2018

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Case Report

Precursor B cell lymphoid blast crisis of chronic myeloid leukemia with novel chromosomal abnormalities: A case report

Hamoud Al‑Khallaf, Hani Alali, Adil Alkhatti
Pages: 6691-6696
Published online on: 25 September 2018

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miR‑221 regulates proliferation and apoptosis of ovarian cancer cells by targeting BMF

Xinping Xie, Yuxiu Huang, Lihong Chen, Jinhua Wang
Pages: 6697-6704
Published online on: 18 September 2018

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Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer

Jinling Zhang, Xueyuan Heng, Yi Luo, Luning Li, Haiyan Zhang, Fengyuan Che, Baosheng Li
Pages: 6705-6712
Published online on: 18 September 2018

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Increased expression of Na+/H+ exchanger isoform 1 predicts tumor aggressiveness and unfavorable prognosis in epithelial ovarian cancer

Haixia Wang, Xingtao Long, Dong Wang, Meng Lou, Dongling Zou, Rui Chen, Weiqi Nian, Qi Zhou
Pages: 6713-6720
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The effect of centromere protein U silencing by lentiviral mediated RNA interference on the proliferation and apoptosis of breast cancer

Shuang‑Yan Lin, Yan‑Bo Lv, Gen‑Xiang Mao, Xu‑Jiao Chen, Fang Peng
Pages: 6721-6728
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Gene networks in basal cell carcinoma of the eyelid, analyzed using gene expression profiling

Tatsuya Yunoki, Yoshiaki Tabuchi, Tetsushi Hirano, Shigeharu Miwa, Johji Imura, Atsushi Hayashi
Pages: 6729-6734
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Acidosis promotes cell apoptosis through the G protein‑coupled receptor 4/CCAAT/enhancer‑binding protein homologous protein pathway

Biao Dong, Xiaolu Zhang, Yafeng Fan, Songqiang Cao, Xuepei Zhang
Pages: 6735-6741
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Hyperthermia enhances the sensitivity of pancreatic cancer SW1990 cells to gemcitabine through ROS/JNK signaling

Hangbin Jin, Yanyan Zhao, Jianfeng Yang, Xiaofeng Zhang, Shenglin Ma
Pages: 6742-6748
Published online on: 18 September 2018

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High levels of glioma tumor suppressor candidate region gene 1 predicts a poor prognosis for prostate cancer

Xiaoming Ma, Tao Du, Dingjun Zhu, Xianju Chen, Yiming Lai, Wanhua Wu, Qiong Wang, Chunhao Lin, Zean Li, Leyuan Liu, Hai Huang
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Anticancer effects of curcumin on nude mice bearing lung cancer A549 cell subsets SP and NSP cells

Xiaojiang Li, Shaojun Ma, Peiying Yang, Binxu Sun, Ying Zhang, Yuehong Sun, Meimei Hao, Ruiyu Mou, Yingjie Jia
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Overexpression of sigma‑1 receptor in MCF‑7 cells enhances proliferation via the classic protein kinase C subtype signaling pathway

Yuqi Wu, Xueyan Bai, Xiaoyang Li, Chang Zhu, Zachary P. Wu
Pages: 6763-6769
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Cross regulation of signaling pathways in gastrointestinal stromal tumor Corrigendum in /10.3892/ol.2023.14103

Yijun Qi, Wendi Zhao, Zhengguang Wang, Qingsong Xie, Jing Cao, Xiangling Meng
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Intervenolin suppresses gastric cancer cell growth through the induction of TSP‑1 secretion from fibroblast‑like stromal cells

Junjiro Yoshida, Hikaru Abe, Takumi Watanabe, Manabu Kawada
Pages: 6777-6785
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Hsa‑miR‑376c‑3p targets Cyclin D1 and induces G1‑cell cycle arrest in neuroblastoma cells

Swapnil Parashram Bhavsar, Cecilie Løkke, Trond Flægstad, Christer Einvik
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Potential role of nuclear magnetic resonance spectroscopy to identify salivary metabolite alterations in patients with head and neck cancer

Jopi J.W. Mikkonen, Surya P. Singh, Ramin Akhi, Tuula Salo, Reijo Lappalainen, Wilfredo A. González‑Arriagada, Márcio Ajudarte Lopes, Arja M. Kullaa, Sami Myllymaa
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Article

Plk1 promotes the migration of human lung adenocarcinoma epithelial cells via STAT3 signaling

Weijuan Yan, Huijie Yu, Wei Li, Fengsheng Li, Sinian Wang, Nan Yu, Qisheng Jiang
Pages: 6801-6807
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Article

Effect of five novel 5‑substituted tetrandrine derivatives on P‑glycoprotein‑mediated inhibition and transport in Caco‑2 cells

Zhonglian Cao, Dan Li, Li Liu, Ping Yang
Pages: 6808-6814
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Article

MicroRNA‑9‑5p functions as a tumor suppressor in papillary thyroid cancer via targeting BRAF

Feng Guo, Xinming Hou, Qinghui Sun
Pages: 6815-6821
Published online on: 07 September 2018

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Article

Effects of FOXM1 inhibition and ionizing radiation on melanoma cells

Vivienne S. Lee, Lucinda S. McRobb, Vaughan Moutrie, Estavam D. Santos, Timothy L. Siu
Pages: 6822-6830
Published online on: 21 September 2018

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Article

Carcinogenesis‑related changes in iron metabolism in chronic obstructive pulmonary disease subjects with lung cancer

Kamil Brzóska, Teresa Bartłomiejczyk, Barbara Sochanowicz, Magdalena Cymerman, Jacek Grudny, Jacek Kołakowski, Marcin Kruszewski, Paweł Śliwiński, Kazimierz Roszkowski‑Śliż, Lucyna Kapka‑Skrzypczak
Pages: 6831-6837
Published online on: 19 September 2018

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Article

Dihydroartemisinin triggers c‑Myc proteolysis and inhibits protein kinase B/glycogen synthase kinase 3β pathway in T‑cell lymphoma cells

Wenwen Wei, Xindong Zhao, Shaoling Wu, Chunting Zhao, Hongguo Zhao, Lingjie Sun, Yujiao Cui
Pages: 6838-6846
Published online on: 18 September 2018

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Article

Transition of serum cytokines following pancreaticoduodenectomy: A subsidiary study of JAPAN‑PD

Hiromichi Maeda, Ken‑Ichi Okada, Tsutomu Fujii, Mari S. Oba, Manabu Kawai, Seiko Hirono, Yasuhiro Kodera, Masayuki Sho, Takahiro Akahori, Yasuhiro Shimizu, Yoshiyasu Ambo, Naru Kondo, Yoshiaki Murakami, Jiro Ohuchida, Hidetoshi Eguchi, Hiroaki Nagano, Junichi Sakamoto, Hiroki Yamaue
Pages: 6847-6853
Published online on: 07 September 2018

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Article

Utilizing ethacrynic acid and ciclopirox olamine in liver cancer

Ahmad M. Al‑Dali, Hans Weiher, Ingo G.H. Schmidt‑Wolf
Pages: 6854-6860
Published online on: 20 September 2018

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Article

Oncological and renal outcomes of segmental ureterectomy vs. radical nephroureterectomy for upper tract urothelial carcinoma

Tomonori Kato, Ryo Nakayama, Tomomi Haba, Makoto Kawaguchi, Akira Komiya, Hiroshi Koike
Pages: 6861-6867
Published online on: 19 September 2018

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Article

Genetic polymorphisms in CDH1 are associated with endometrial carcinoma susceptibility among Chinese Han women

Yue‑Hang Geng, Zi‑Fan Wang, Yu‑Mian Jia, Li‑Yuan Zheng, Lan Chen, Dong‑Ge Liu, Xiang‑Hong Li, Xin‑Xia Tian, Wei‑Gang Fang
Pages: 6868-6878
Published online on: 20 September 2018

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June-2026 Volume 31 Issue 6

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Review
Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Article Open Access

Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Article Open Access

Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Article Open Access

Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Article Open Access

Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Review Open Access

Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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Article Open Access

METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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July-2026 Volume 32 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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